Lipossigenasi
Le lipossigenasi sono una famiglia di enzimi che catalizzano l'ossigenazione degli acidi grassi polinsaturi, portando alla produzione di mediatori lipidici bioattivi come i leucotrieni e le lipossine. Questi mediatori svolgono ruoli critici nell'infiammazione, nelle risposte immunitarie e nel cancro. Gli inibitori della lipossigenasi sono utilizzati per studiare il loro ruolo nelle malattie infiammatorie, nell'asma e nel cancro. Presso CymitQuimica, offriamo una varietà di inibitori della lipossigenasi per supportare la tua ricerca in infiammazione, oncologia e metabolismo lipidico.
Trovati 132 prodotti per "Lipossigenasi".
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Setileuton tosylate
CAS:Setileuton (MK0633): a potent 5-lipoxygenase inhibitor, researched for asthma and atherosclerosis treatment.Formula:C29H25F4N3O7SColore e forma:SolidPeso molecolare:635.58PF-4191834
CAS:PF-4191834: Non-iron, non-redox 5-LOX inhibitor, IC50 = 229 nM, 300x selective over 12/15-LOX, inactive on COX enzymes.Formula:C22H23N3O2SPurezza:99.83% - 99.98%Colore e forma:White SolidPeso molecolare:393.5Ref: TM-T16503
5mg50,00€1mL*10mM (DMSO)55,00€10mg79,00€25mg146,00€50mg245,00€100mg355,00€500mg772,00€Lonapalene
CAS:Lonapalene is a topically effective inhibitor of 5-lipoxygenase.Formula:C16H15ClO6Purezza:98.67% - 99.33%Colore e forma:SolidPeso molecolare:338.74Ref: TM-T16802
1mg100,00€2mg160,00€5mg290,00€1mL*10mM (DMSO)318,00€10mg424,00€25mg642,00€50mg858,00€100mg1.153,00€200mg1.558,00€Butibufen
CAS:Butibufen (FF-106) is a non-steroidal anti-inflammatory compound and LOX inhibitor with analgesic and antipyretic activity for the study of rheumatic diseases.Formula:C14H20O2Purezza:98.11% - 98.95%Colore e forma:SolidPeso molecolare:220.315-LOX-IN-1
CAS:5-LOX-IN-1 is a 5-Lipoxygenase (5-LOX) inhibitor (IC50: 2.3 μM).5-LOX-IN-1 can be used for cancer research.Formula:C20H18N2O2SPurezza:97.09%Colore e forma:SolidPeso molecolare:350.43A-69412
CAS:A-69412 is a reversible 5-lipoxygenase inhibitor, potentially treating ulcerative colitis and asthma.Formula:C7H10N2O3Purezza:99.54%Colore e forma:SolidPeso molecolare:170.17Benoxaprofen
CAS:Benoxaprofen (NSC-299582) is a non-steroidal anti-inflammatory drug.Formula:C16H12ClNO3Purezza:98.87%Colore e forma:SolidPeso molecolare:301.72Ref: TM-T19679
1mg192,00€1mL*10mM (DMSO)444,00€5mg447,00€10mg670,00€25mg982,00€50mg1.243,00€100mg1.575,00€L 670630
CAS:L 670630 is a potent and orally active 5-lipoxygenase inhibitor.Formula:C25H26O3Purezza:98%Colore e forma:SolidPeso molecolare:374.47AA 863
CAS:AA 863 is a 5-lipoxygenase inhibitor, it inhibits the proliferation of human glioma cell lines in dose-dependent.Formula:C21H26O5Purezza:98%Colore e forma:SolidPeso molecolare:358.43A 79175
CAS:A 79175 is a 5-lipoxygenase inhibitor that increases bone formation.Formula:C15H13FN2O4Purezza:98%Colore e forma:SolidPeso molecolare:304.2715(S)-HEDE
CAS:15(S)-HEDE is produced from 11Z,14Z-eicosadienoic acid by 15-LO. 15(S)-HEDE is an inhibitor of RBL-1 cell 5-LO with an IC50 value of 26 μM.Formula:C20H36O3Colore e forma:SolidPeso molecolare:324.5A 78773
CAS:A 78773: potent reversible 5-lipoxygenase inhibitor; active in cells/tissues; targets inflammation, asthma, IBD.Formula:C15H13FN2O4Colore e forma:SolidPeso molecolare:304.275,6-dehydro Arachidonic Acid
CAS:5,6-dehydro Arachidonic acid, an arachidonic acid analog with a 5,6 acetylene, inhibits 5-LO; Ki=15 μM in RBL cells, IC50=10 μM in guinea pig leukocytes.Formula:C20H30O2Colore e forma:SolidPeso molecolare:302.45h15-LOX-2 inhibitor 1
CAS:Compound 105 (h15-LOX-2 inhibitor 1) is a potent inhibitor of human epithelial 15-lipoxygenase-2 (h15-LOX-2), exhibiting an IC50 of 0.34 μM [1].Formula:C17H13F3N2SPurezza:98%Colore e forma:SolidPeso molecolare:334.36CMI-392
CAS:CMI-392 is a dual 5-lipoxygenase inhibitor and platelet-activating factor (PAF) receptor antagonist (IC50s: 100 and 10 nM).Formula:C31H37ClN2O8SPurezza:98%Colore e forma:SolidPeso molecolare:633.15TA-270
CAS:TA-720, a 5-lipoxygenase inhibitor, is used potentially for the treatment of asthma.Formula:C29H36N2O7Colore e forma:SolidPeso molecolare:524.615-Lipoxygenase-In-1
CAS:5-Lipoxygenase-In-1 (compound example 4.10) is a 5-Lipoxygenase inhibitor.Formula:C23H28N4O2SColore e forma:SolidPeso molecolare:424.56MLS000545091
CAS:MLS000545091 is a potent and selective human epithelial 15-lipoxygenase-2 mixed-type inhibitor.Formula:C14H15ClN2OPurezza:99.84%Colore e forma:SolidPeso molecolare:262.7317(S)-HpDHA
CAS:17(S)-HpDHA, primarily produced by the 15-Lipoxygenase (LOX) isoenzymes h15-LOX-1 and h15-LOX-2 from docosahexaenoic acid (DHA), is a key regulator in epoxide synthesis through allosteric modulation. Additionally, it effectively inhibits platelet aggregation, demonstrating an EC50 of approximately 1 μM [1].Formula:C22H32O4Colore e forma:SolidPeso molecolare:360.49(2E,9Z)-Octadeca-2,9-dienoic acid
CAS:(2E,9Z)-Octadeca-2,9-dienoic acid, a polyunsaturated fatty acid, is utilized in the study of lipoxygenase-dependent metabolism [1].Formula:C18H32O2Colore e forma:SolidPeso molecolare:280.45
