Fosfolipasi
Le fosfolipasi sono un gruppo di enzimi che idrolizzano i fosfolipidi in acidi grassi e altre sostanze lipofile, svolgendo un ruolo critico nella biologia delle membrane e nella generazione di molecole segnalatrici. Gli inibitori delle fosfolipasi vengono utilizzati per studiare il loro ruolo nelle malattie infiammatorie, nei disturbi cardiovascolari e nella neurodegenerazione. Questi inibitori sono anche preziosi per esplorare le vie di segnalazione lipidica e le loro implicazioni nei meccanismi delle malattie. Presso CymitQuimica, offriamo una varietà di inibitori delle fosfolipasi per supportare la tua ricerca in infiammazione, metabolismo lipidico e segnalazione cellulare.
Trovati 84 prodotti per "Fosfolipasi".
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Lansoprazole
CAS:Lansoprazole (A-65006) is a 2, 2, 2-trifluoroethoxypyridyl derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISONFormula:C16H14F3N3O2SPurezza:99.18% - 99.84%Colore e forma:Yellow SolidPeso molecolare:369.36Tris(2,4-di-tert-butylphenyl)phosphate
CAS:Tris(2,4-di-tert-butylphenyl)phosphate (TDTBPP) inhibits secretory phospholipase A2 (sPLA2) with anti-inflammatory effect. Cost-effective and quality-assured.Formula:C42H63O4PPurezza:99.73%Colore e forma:SolidPeso molecolare:662.92Lp-PLA2-IN-1
CAS:Lp-PLA2-IN-1 suppresses Lp-PLA2, aiding in treating atherosclerosis and Alzheimer's.Formula:C21H17F5N4O3Purezza:99.60%Colore e forma:White SolidPeso molecolare:468.38Omeprazole
CAS:Omeprazole (Losec) is a proton pump inhibitor (PPI), Omeprazole(Losec) is a potent brain penetrant neutral sphingomyelinase (N-SMase) inhibitor.Formula:C17H19N3O3SPurezza:98.43% - 98.48%Colore e forma:Brown SolidPeso molecolare:345.42ML349
CAS:ML349 is an inhibitor of LYPLA2 (IC50: 144 nM). ML349 is an effective and specific acyl protein thioesterase 2 (APT-2) inhibitor (Ki: 120 nM).Formula:C23H22N2O4S2Purezza:99.59% - 99.88%Colore e forma:SolidPeso molecolare:454.56A4333
A4333, a biotinylated derivative of A3373, selectively inhibits Phospholipase D1 (PLD1) while sparing PLD2.Purezza:98%Colore e forma:Odour SolidASM-IN-3
CAS:ASM-IN-3 (Compound 21b) is a selective acid sphingomyelinase (ASM) inhibitor that can penetrate the blood-brain barrier, with an IC50 of 3.37 μM against purified human ASM. By inhibiting ASM activity in the hippocampus and promoting neurogenesis, ASM-IN-3 alleviates depressive-like behavior in reserpine-induced depressive rats.Formula:C17H13ClN2O4Colore e forma:SolidPeso molecolare:344.751-Myristoyl-2-Linoleoyl-sn-glycero-3-PC
CAS:1-Myristoyl-2-Linoleoyl-sn-glycero-3-PC is a phospholipid identified in human plasma, characterized by the presence of Myristic acid and Linoleic acid at the sn-1 and sn-2 positions, respectively.Formula:C40H76NO8PColore e forma:SolidPeso molecolare:730.01SB-435495
CAS:SB-435495 is a compound characterized by its potent, selective, reversible, and non-covalent inhibition of Lp-PLA2, demonstrating an IC50 value of 0.06 nM.Formula:C38H40F4N6O2SPurezza:99.07%Colore e forma:White SolidPeso molecolare:720.821,2-Bis(heptanoylthio)-sn-glycero-3-PG sodium
1,2-Bis(heptanoylthio)-sn-glycero-3-PG [1,2-Bis(heptanoylthio) glycerophosphatidylglycerol] sodium is a thioesterified phosphatidylglycerol derivative. It can be utilized to mimic phospholipase activity or serve as a probe molecule in membrane fusion studies.Colore e forma:Odour SolidAACOCF3
CAS:AACOCF3 (Arachidonyl trifluoromethyl ketone) is a cell-permeable trifluoromethyl ketone analog of arachidonic acid.Formula:C21H31F3OPurezza:99% - 99%Colore e forma:SolidPeso molecolare:356.47Compound 48/80 trihydrochloride
CAS:Compound 48/80 trihydrochloride (C48/80 trihydrochloride) is a mixture of N-methyl-p-methoxyphenethylamine and formaldehyde produced via a condensation reaction.Formula:C32H48Cl3N3O3Purezza:98% - 99.24%Colore e forma:White SolidPeso molecolare:629.1DPTIP
CAS:DPTIP is an effective inhibitor of neutral sphingomyelinase 2 with an IC50 value of 30 nM.Formula:C21H18N2O3SPurezza:99.88%Colore e forma:SolidPeso molecolare:378.44Ref: TM-T60043
1mg46,00€2mg59,00€5mg90,00€1mL*10mM (DMSO)90,00€10mg144,00€25mg281,00€50mg462,00€100mg672,00€Melittin Acetate
Melittin Acetate, a PLA2 activator, enhances low-weight PLA2 activity but not high-weight PLA2.Formula:C133H233N39O33Purezza:99.65%Colore e forma:SolidPeso molecolare:2906.51sPLA2 inhibitor 2
sPLA2 inhibitor 2 (compound 6a) is an sPLA2 inhibitor with an IC50 value of 0.0475 μM, making it valuable for diabetes research.Formula:C20H18N6O4S2Colore e forma:SolidPeso molecolare:470.52LEI110
CAS:LEI110 inhibits PLA2G16 and HRASLS enzymes, Ki 20 nM, selectively targets related thiol hydrolases.Formula:C25H23F3N2O3Purezza:98.66% - 99.01%Colore e forma:SolidPeso molecolare:456.46VU533
CAS:VU533 is a NAPE-PLD activator, EC50=0.30 µM, boosts macrophage activity, potential in cardiometabolic diseases.Formula:C21H22FN3O3S2Purezza:99.87%Colore e forma:SolidPeso molecolare:447.55PLA2-IN-1
PLA2-IN-1 (Compound 7) is a potent and selective inhibitor of phospholipase A (PLA2) with an IC50 value of 1 nM. It effectively inhibits PLA2-induced coagulation disorders in vitro and shows potential for use as an antidote for snake bites caused by cobra venom.Colore e forma:Odour SolidA3373
CAS:A3373 is a novel inhibitor targeting both Phospholipase D1 (PLD1) and Phospholipase D2 (PLD2), demonstrating half maximal inhibitory concentrations (IC50) ofFormula:C17H9F7N2OPurezza:98%Colore e forma:SolidPeso molecolare:390.26nSMase2-IN-1
nSMase2-IN-1 is an orally active inhibitor of Neutral sphingomyelinase 2 (nSMase2) with a potent IC50 value of 0.13 ± 0.06 μM.Formula:C12H17N5OPurezza:98%Colore e forma:SolidPeso molecolare:247.3Varespladib sodium
CAS:Varespladib sodium is a potent sPLA2 inhibitor (IC50≈9 nM).Formula:C21H19N2NaO5Peso molecolare:402.38OBAA
CAS:OBAA is a broad-spectrum PLA2 inhibitor; anti-inflammatory agent; blocks arachidonic acid; inflammation research.Formula:C28H44O3Purezza:98%Colore e forma:White SolidPeso molecolare:428.65Difluprednate (Standard)
CAS:Difluprednate (Standard) is the standard substance of Difluprednate, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Difluprednate (Myser)(Durezol) is a corticosteroid, approved for the treatment of post-operative ocular inflammation and pain.Formula:C27H34F2O7Colore e forma:SolidPeso molecolare:508.55MJ33 lithium salt
CAS:MJ33 lithium salt is an inhibitor of NADPH oxidase type 2-mediated ROS generation, inhibits PLA2 activity, and can be used to study acute lung injury.Formula:C22H43F3LiO6PPurezza:99%Colore e forma:SolidPeso molecolare:498.48Phospholipase A2
CAS:Phospholipase A2 (PLA2) is an enzyme that hydrolyzes fatty acids present in the sn-2 position of phospholipids and is closely related to lipid metabolism.Colore e forma:SolidPACOCF3
CAS:PACOCF3, a phospholipase A2 inhibitor, hinders Ca2+ signaling with an IC50 of 3.8 μM in renal cells.Formula:C17H31F3OPurezza:99.93%Colore e forma:White SolidPeso molecolare:308.42Bromoenol lactone
CAS:NeurokininBromoenol lactone ((6E)-Bromoenol lactone) is an iPLA2β and serine protease inhibitor that attenuates nicotine-induced breast cancer cell proliferation.Formula:C16H13BrO2Purezza:99.98%Colore e forma:White SolidPeso molecolare:317.18LEI-401
CAS:LEI-401 is a NAPE-PLD inhibitor.LEI-401 reduces the level of n-acyl ethanolamines in the brain of free-ranging mice and modulates their emotional behaviour.Formula:C24H31N5O2Purezza:99.11% - 99.79%Colore e forma:SolidPeso molecolare:421.54BMS493
CAS:BMS493 is an inverse agonist of RAR that inhibits retinoic acid-induced differentiation and inhibits the increase in phospholipase A2 activity.Formula:C29H24O2Purezza:99.12% - >99.99%Colore e forma:SolidPeso molecolare:404.5BAPTA
CAS:BAPTA is a neuroprotective agent in cerebral ischemia, acting as an intercellular Ca2+ chelator.Formula:C22H24N2O10Purezza:97.21% - ≥95%Colore e forma:SolidPeso molecolare:476.43RHC 80267
CAS:RHC 80267 (U-57908) is a selective inhibitor of DAGL (IC50 : 4 μM in canine platelets)Formula:C20H34N4O4Purezza:99.54%Colore e forma:White SolidPeso molecolare:394.51GW4869
CAS:GW4869 (GW69A) is a selective and non-competitive inhibitor of neutral sphingomyelinase N-SMase (IC50=1 μM).Formula:C30H30Cl2N6O2Purezza:98.12% - 98.47%Colore e forma:SolidPeso molecolare:577.5Anti-Inflammatory Peptide 1 Acetate
Anti-Inflammatory Peptide 1 Acetate (C45H82N12O14S2) inhibits PLA2 to reduce inflammation and pain.Formula:C47H86N12O16S2Purezza:98.95%Colore e forma:White SolidPeso molecolare:1139.39Varespladib
CAS:Varespladib (LY315920) inhibits hnsPLA2 effectively (IC50=7 nM), studied for sickle cell, VOC, and acute coronary syndrome.Formula:C21H20N2O5Purezza:99.97%Colore e forma:White SolidPeso molecolare:380.39Ref: TM-T2044
1mg43,00€1mL*10mM (DMSO)77,00€5mg93,00€10mg137,00€25mg215,00€50mg319,00€100mg462,00€200mg668,00€FIPI
CAS:FIPI, a halopemide derivative, strongly blocks PLD1 and PLD2 (IC50s: 25 nM, 20 nM) and hinders PLD-mediated cell activity.Formula:C23H24FN5O2Purezza:97.21% - 98.68%Colore e forma:White SolidPeso molecolare:421.471-Linoleoyl Glycerol
CAS:1-Linoleoyl Glycerol (Monolinolein) is fatty acid glycerol that has been isolated from Saururus Chinensis roots.Formula:C21H38O4Purezza:98.95% - 99.15%Colore e forma:SolidPeso molecolare:354.52ML348
CAS:ML348 (GNF-Pf-1127) is a selective and reversible lysophospholipase 1 (LYPLA1) inhibitor (IC50 = 210 nM).Formula:C18H17ClF3N3O3Purezza:99% - 99.88%Colore e forma:SolidPeso molecolare:415.79Ref: TM-T3439
2mg44,00€5mg65,00€10mg92,00€25mg215,00€50mg334,00€100mg537,00€200mg750,00€500mg1.134,00€ONO-RS-082
CAS:ONO-RS-082 is a Ca2+-independent phospholipase A2 inhibitor.Formula:C21H22ClNO3Purezza:99.35%Colore e forma:SolidPeso molecolare:371.86AA26-9
CAS:AA26-9 is an effective and broad-spectrum inhibitor of serine hydrolase.Formula:C7H10N4OPurezza:99.88%Colore e forma:White SolidPeso molecolare:166.18Ref: TM-T3990
1mg34,00€2mg49,00€5mg74,00€1mL*10mM (DMSO)82,00€10mg113,00€25mg200,00€50mg333,00€100mg495,00€ML-211
CAS:ML-211 is a carbamate-based dual inhibitor of LYPLA1 (IC50 = 17 nM) and the related LYPLA2 (IC50 = 30 nM)Formula:C25H30N4O2Purezza:97.07%Colore e forma:SolidPeso molecolare:418.53Ref: TM-T8974
1mg114,00€1mL*10mM (DMSO)219,00€5mg222,00€10mg313,00€25mg497,00€50mg670,00€100mg888,00€1-Naphthaleneacetic acid potassium salt
CAS:1-Naphthaleneacetic acid potassium salt (1-NAA Potassium Salt) is a synthetic phytogrowth hormone that promotes plant growth and a PLA2 inhibitor.Formula:C12H9O2·KPurezza:97.68%Colore e forma:Off-White To Beige PowderPeso molecolare:224.3Difluprednate
CAS:Difluprednate (Myser)(Durezol) is a corticosteroid, approved for the treatment of post-operative ocular inflammation and pain.Formula:C27H34F2O7Purezza:99.23% - 99.86%Colore e forma:SolidPeso molecolare:508.55Cambinol
CAS:Cambinol is a SIRT1/2 inhibitor (IC50: 56/59 μM), non-competitive with NAD, weak on SIRT5, and prompts apoptosis in lymphoma cells.Formula:C21H16N2O2SPurezza:98.02% - 99.83%Colore e forma:SolidPeso molecolare:360.43Ref: TM-T4019
1mg38,00€2mg50,00€1mL*10mM (DMSO)63,00€5mg80,00€10mg117,00€25mg207,00€50mg333,00€100mg495,00€500mg1.071,00€CAY10594
CAS:CAY10594, a PLD2 inhibitor, mitigates acetaminophen liver damage via the p-GSK-3β/JNK pathway.Formula:C26H28N4O2Purezza:98%Colore e forma:White SolidPeso molecolare:428.53trans-Benzylideneacetone
CAS:trans-Benzylideneacetone (Acetocinnamone) is used in various synthetic preparations.Formula:C10H10OPurezza:97.48%Colore e forma:SolidPeso molecolare:146.19Aristolochic acid C
CAS:Aristolochic acid C is a derivative of Aristolochic acid which is a phospholipase A2 inhibitor.Formula:C16H9NO7Purezza:99.8%Colore e forma:Orange SolidPeso molecolare:327.25CAY10650
CAS:CAY10650 is an effective inhibitor of cytosolic phospholipase A2α (cPLA2α, IC50: 12 nM).Formula:C28H25NO6Purezza:97.33%Colore e forma:SolidPeso molecolare:471.5Ref: TM-TQ0105
1mg49,00€5mg114,00€1mL*10mM (DMSO)118,00€10mg172,00€25mg334,00€50mg467,00€100mg620,00€U-73122
CAS:U-73122 (U73122) , an effective PLC inhibitor, reduces agonist-induced Ca2+ increases in platelets and PMN.Formula:C29H40N2O3Purezza:97.50% - 98.66%Colore e forma:White SolidPeso molecolare:464.64m-3M3FBS
CAS:m-3M3FBS is a phospholipase C (PLC) activator.Formula:C16H16F3NO2SPurezza:99.66%Colore e forma:SolidPeso molecolare:343.36N-(p-amylcinnamoyl) Anthranilic Acid
CAS:N-(p-amylcinnamoyl) Anthranilic Acid (ACA) is a broad spectrum Phospholipase A2 (PLA2) inhibitor and TRP channel blocker.Formula:C21H23NO3Purezza:99.35% - 99.67%Colore e forma:White SolidPeso molecolare:337.41
