Fosfolipasi
Le fosfolipasi sono un gruppo di enzimi che idrolizzano i fosfolipidi in acidi grassi e altre sostanze lipofile, svolgendo un ruolo critico nella biologia delle membrane e nella generazione di molecole segnalatrici. Gli inibitori delle fosfolipasi vengono utilizzati per studiare il loro ruolo nelle malattie infiammatorie, nei disturbi cardiovascolari e nella neurodegenerazione. Questi inibitori sono anche preziosi per esplorare le vie di segnalazione lipidica e le loro implicazioni nei meccanismi delle malattie. Presso CymitQuimica, offriamo una varietà di inibitori delle fosfolipasi per supportare la tua ricerca in infiammazione, metabolismo lipidico e segnalazione cellulare.
Trovati 83 prodotti di "Fosfolipasi"
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CAY10594
CAS:CAY10594, a PLD2 inhibitor, mitigates acetaminophen liver damage via the p-GSK-3β/JNK pathway.Formula:C26H28N4O2Purezza:98%Colore e forma:SolidPeso molecolare:428.53trans-Benzylideneacetone
CAS:trans-Benzylideneacetone (Acetocinnamone) is used in various synthetic preparations.Formula:C10H10OPurezza:97.48%Colore e forma:Light Yellow Low Melting Crystalline MassPeso molecolare:146.19Aristolochic acid C
CAS:<p>Aristolochic acid C is a derivative of Aristolochic acid which is a phospholipase A2 inhibitor.</p>Formula:C16H9NO7Purezza:99.8%Colore e forma:White PowderPeso molecolare:327.25CAY10650
CAS:CAY10650 is an effective inhibitor of cytosolic phospholipase A2α (cPLA2α, IC50: 12 nM).Formula:C28H25NO6Purezza:97.33%Colore e forma:SolidPeso molecolare:471.5Ref: TM-TQ0105
1mg51,00€5mg120,00€10mg175,00€25mg354,00€50mg494,00€100mg655,00€1mL*10mM (DMSO)125,00€U-73122
CAS:U-73122 (U73122) , an effective PLC inhibitor, reduces agonist-induced Ca2+ increases in platelets and PMN.Formula:C29H40N2O3Purezza:97.50%Colore e forma:Solid Off-WhitePeso molecolare:464.64m-3M3FBS
CAS:m-3M3FBS is a phospholipase C (PLC) activator.Formula:C16H16F3NO2SPurezza:99.66%Colore e forma:SolidPeso molecolare:343.36Melittin
CAS:Melittin: principal bee venom toxin, 26 amino acids, activates low-weight PLA2, not high-weight PLA2.Formula:C131H229N39O31Purezza:98.37% - 99.92%Colore e forma:SolidPeso molecolare:2846.46Neomycin sulfate
CAS:Neomycin sulfate (Framycin sulfate) is a broad-spectrum aminoglycoside antibiotic that blocks the synthesis of bacterial proteins in order to exertFormula:C23H46N6O13·3H2SO4Purezza:99.4% - 99.88%Colore e forma:Tan PowderPeso molecolare:908.87VU0155056
CAS:VU0155056 is a dual PLD1/2 inhibitor with IC50 < 1 µM in cellular assays, inhibits breast cancer cell invasion.Formula:C25H26N4O2Purezza:98.6% - 99.15%Colore e forma:SolidPeso molecolare:414.5LCL521
CAS:LCL521 inhibits lysosomal acid sphingomyelinase (ASMase).LCL521 is an acid ceramidase (ACDase) inhibitor.Formula:C31H52N4O7Purezza:98%Colore e forma:SolidPeso molecolare:592.77Omeprazole Sodium
CAS:Omeprazole Sodium is a proton pump inhibitor(PPI) and suppresses gastric acid secretion.Formula:C17H18N3NaO3SPurezza:99.84%Colore e forma:Clear In WaterPeso molecolare:367.42-(E-2-decenoylamino)ethyl 2-(cyclohexylethyl) sulfide
CAS:2-Decenoylaminoethyl cyclohexylethyl sulfide prevents stress ulcers, stabilizes phospholipase A2 and prostaglandin E2.Formula:C20H37NOSPurezza:98%Colore e forma:SolidPeso molecolare:339.58ML299
CAS:ML299 (VU0463568) is a dual PLD1/2 inhibitor (PLD1 and PLD2, IC50 of 6 nM, 20 nM, respectively).Formula:C23H26BrFN4O2Purezza:98%Colore e forma:SolidPeso molecolare:489.38Lp-PLA2-IN-3
CAS:Lp-PLA2-IN-3: Potent oral inhibitor of human Lp-PLA2 with a 14 nM IC50.Formula:C20H13ClF3N3O3SPurezza:99.84%Colore e forma:SolidPeso molecolare:467.85Ref: TM-T11874
1mg96,00€2mg139,00€5mg227,00€10mg359,00€25mg595,00€50mg842,00€100mg1.121,00€500mg2.262,00€1mL*10mM (DMSO)233,00€ASM-IN-1
CAS:ASM-IN-1: Oral acid sphingomyelinase inhibitor, IC50 = 1.5 µM; reduces lipid plaques, plasma ceramide, Ox-LDL.Formula:C16H12BrN3O4Purezza:98%Colore e forma:SolidPeso molecolare:390.19GK187
CAS:GK187 is a selective and potent Group VIA calcium-independent phospholipase A2 (GVIA iPLA2) inhibitor, used in the study of neurological disorders.Formula:C14H15F5O2Colore e forma:SolidPeso molecolare:310.26Ref: TM-T37221
1mg84,00€5mg175,00€10mg283,00€25mg538,00€50mg847,00€100mg1.378,00€1mL*10mM (DMSO)188,00€Halopemide
CAS:Halopemide is a potent inhibitor of PLD (IC50 = 220 and 310 nM for human PLD1 and PLD2).Formula:C21H22ClFN4O2Purezza:96.57%Colore e forma:SolidPeso molecolare:416.88Giripladib
CAS:<p>Giripladib (PLA695/PLX-695) blocks radiation-boosted phosphorylation of ERK and Akt in endothelial cells.</p>Formula:C41H36ClF3N2O4SPurezza:99.64%Colore e forma:SolidPeso molecolare:745.25VU0155069
CAS:VU0155069, a selective PLD1 inhibitor (IC50: 46 nM), halts cancer cell migration in transwell assays.Formula:C26H27ClN4O2Purezza:99.5%Colore e forma:SolidPeso molecolare:462.97VU0364739
CAS:VU0364739, a selective phospholipase D2 (PLD2) inhibitor with an IC50 of 22 nM, effectively reduces cancer cell proliferation [1].Formula:C26H27FN4O2Purezza:98%Colore e forma:SolidPeso molecolare:446.52Lp-PLA2-IN-13
CAS:Lp-PLA2-IN-13 (compound 15), a potent Lp-PLA2 inhibitor, holds potential for research in neurodegenerative-related diseases [1].Formula:C22H17F5N4O4Purezza:98%Colore e forma:SolidPeso molecolare:496.39Lp-PLA2-IN-2
CAS:Lp-PLA2-IN-2 is a selective and potent lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitor, with an IC50 0f 120 nM for recombinant human Lp-PLA2.Formula:C19H23FN2O4SPurezza:98%Colore e forma:SolidPeso molecolare:394.46Lp-PLA2-IN-14
CAS:Lp-PLA2-IN-14 (Compound 19), an inhibitor of rhLp-PLA2, exhibits a potent inhibitory effect with a pIC50 value of 8.4.Formula:C16H14F3N3O3Purezza:98%Colore e forma:SolidPeso molecolare:353.37,7-Dimethyl-(5Z,8Z)-eicosadienoic acid
CAS:7,7-Dimethyl-(5Z,8Z)-eicosadienoic acid (DEDA, 5 μM) significantly impacts the response to βA(25-35) stimulation. It reduces the formation of ROS.Formula:C22H40O2Colore e forma:SolidPeso molecolare:336.55Varespladib methyl
CAS:Varespladib methyl (LY333013), a bioavailable prodrug of Varespladib, is a selective group II secretory phospholipase A2 inhibitor.Formula:C22H22N2O5Purezza:99.42% - 99.97%Colore e forma:SolidPeso molecolare:394.42Ref: TM-T17218
1mg87,00€2mg130,00€5mg210,00€10mg338,00€25mg557,00€50mg770,00€100mg1.054,00€200mg1.406,00€1mL*10mM (DMSO)233,00€Ecopladib
CAS:<p>Ecopladib inhibits cPLA2α with IC50 of 0.15 μM (micelles) & 0.11 μM (rat blood).</p>Formula:C39H33Cl3N2O5SPurezza:95.15%Colore e forma:SolidPeso molecolare:748.11Rilapladib
CAS:Rilapladib (SB 659032) is a selective inhibitor of Lipoprotein-Associated Phospholipase A2(Lp-PLA2, IC50 = 230 pM) and an antagonist of the platelet activatingFormula:C40H38F5N3O3SPurezza:99.92%Colore e forma:SolidPeso molecolare:735.8Ref: TM-T16751
1mg93,00€5mg227,00€10mg369,00€25mg567,00€50mg787,00€100mg1.169,00€200mg1.586,00€1mL*10mM (DMSO)368,00€MAFP
CAS:MAFP (Methyl Arachidonyl Fluorophosphonate) is an effective irreversible inhibitor of anandamide amidase.Formula:C21H36FO2PColore e forma:SolidPeso molecolare:370.48GK420
CAS:GK420 (AVX420) is a potent inhibitor of cytoplasmic phospholipase A2α (cPLA2α), with an XI(50) value of 0.0016. It effectively inhibits the release of arachidonic acid, with an EC50 of 0.09 μM. GK420 plays a significant role in cancer research.Formula:C20H25NO5SColore e forma:SolidPeso molecolare:391.481Ro 23-9358
CAS:Ro 23-9358 is a potent inhibitor of secretory phospholipase A2, exhibiting anti-inflammatory properties.Formula:C30H51NO6Colore e forma:SolidPeso molecolare:521.729Lp-PLA2-IN-16
CAS:<p>Lp-PLA2-IN-16 (Example 1) is an inhibitor of lipoprotein-associated phospholipase A2 (Lp-PLA2) with potential applications in Alzheimer's disease research [1].</p>Formula:C22H17F5N4O3Purezza:98%Colore e forma:SolidPeso molecolare:480.39Ref: TM-T79076
Prodotto fuori produzioneLp-PLA2-IN-12
CAS:<p>Lp-PLA2-IN-12 (compound 19), an Lp-PLA2 inhibitor, is utilized in researching neurodegenerative diseases including Alzheimer's disease (AD), glaucoma, age-</p>Formula:C24H23F2N5O3Purezza:98%Colore e forma:SolidPeso molecolare:467.47Ref: TM-T79010
Prodotto fuori produzioneLp-PLA2-IN-15
CAS:<p>Lp-PLA2-IN-15 (example 2) is an inhibitor of lipoprotein-associated phospholipase A2 (Lp-PLA2) with potential application in Alzheimer's disease research [1].</p>Formula:C22H17F5N4O3Purezza:98%Colore e forma:SolidPeso molecolare:480.39Ref: TM-T79075
Prodotto fuori produzione
