recettore 5-HT
I recettori 5-HT, noti anche come recettori della serotonina, sono un gruppo di recettori accoppiati alle proteine G (GPCR) che mediano gli effetti della serotonina, un neurotrasmettitore coinvolto nella regolazione dell'umore, dell'ansia, del sonno, dell'appetito e di altri processi fisiologici. Questi recettori sono suddivisi in diversi sottotipi, ciascuno con funzioni e proprietà farmacologiche distinte. I modulatori dei recettori 5-HT sono ampiamente studiati per il loro ruolo nel trattamento della depressione, dei disturbi d'ansia e di altre condizioni neuropsichiatriche. Presso CymitQuimica, offriamo una gamma di modulatori dei recettori 5-HT di alta qualità per supportare la tua ricerca in neurofarmacologia, disturbi dell'umore e segnalazione GPCR.
Trovati 942 prodotti di "recettore 5-HT"
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Zicronapine
CAS:<p>Zicronapine (LU 31-130), an atypical antipsychotic with monoaminergic action, targets dopamine D1/D2 and serotonin 5HT2A.</p>Formula:C22H27ClN2Colore e forma:SolidPeso molecolare:354.92EMD 56551
CAS:<p>EMD 56551 is a selective small molecule 5-HT1A receptor agonist with anxiolytic activity for the study of anxiety disorders.</p>Formula:C24H31N3O2Purezza:95.64% - 99.39%Colore e forma:SolidPeso molecolare:393.522PF-04781340
CAS:PF-04781340 is an effective, selective, and CNS penetrant agonist of 5-HT2C receptor.Formula:C17H21N3Purezza:98%Colore e forma:SolidPeso molecolare:267.37FR260010
CAS:<p>FR260010 is a novel potent serotonin 5-HT2C receptor antagonist.</p>Formula:C22H19N5Colore e forma:SolidPeso molecolare:353.42TC-2153
CAS:<p>TC-2153 inhibits STEP, boosts BDNF, lowers MAOA/5-HT1A mRNA, and blocks 5-HT2A signaling with low toxicity.</p>Formula:C7H5ClF3NS5Colore e forma:SolidPeso molecolare:355.89Alaproclate
CAS:<p>Alaproclate is a non-competitive NMDA receptor antagonist and a new selective 5-HT uptake inhibitor for the study of depression and dementia.</p>Formula:C13H18ClNO2Purezza:98.29% - 98.64%Colore e forma:SolidPeso molecolare:255.74LP44 hydrochloride
CAS:<p>LP44 hydrochloride is a 5-HT7 agonist with analgesic effects on formalin-induced orofacial pain in mice and can be used to study neuroinflammation.</p>Formula:C27H38ClN3OSPurezza:98.06%Colore e forma:SolidPeso molecolare:488.13Belaperidone
CAS:<p>Belaperidone, an antipsychotic, resembles clozapine, binds D(4) and 5-HT(2A) receptors, minimally extends Q-T without causing arrhythmias.</p>Formula:C22H22FN3O2Colore e forma:SolidPeso molecolare:379.43CP 93129 dihydrochloride
CAS:<p>5-HT1B agonist, potent and highly selective</p>Formula:C12H14ClN3OPurezza:98%Colore e forma:SolidPeso molecolare:251.71CGS 12066B dimaleate
CAS:<p>5-HT1B full agonist</p>Formula:C25H25F3N4O8Purezza:98%Colore e forma:SolidPeso molecolare:566.485-HT6/5-HT2A receptor ligand-2
CAS:<p>Compound 42: brain-penetrant, dual 5-HT6/5-HT2A antagonist, Ki of 25 nM/32 nM, pro-cognitive.</p>Formula:C20H18FN3O2Colore e forma:SolidPeso molecolare:351.37CP 135807
CAS:<p>CP 135807 is a 5-HT1D receptor agonist.</p>Formula:C19H21N5O2Purezza:98%Colore e forma:SolidPeso molecolare:351.45-HT7 agonist 2
CAS:<p>Potent 5-HT7 agonist with 28.7 nM IC50; promising for CNS disorder research.</p>Formula:C23H29N3OColore e forma:SolidPeso molecolare:363.5Prucalopride hydrochloride
CAS:<p>Prucalopride hydrochloride is a selective agonist of the 5-HT4.</p>Formula:C18H27Cl2N3O3Purezza:98%Colore e forma:SolidPeso molecolare:404.33WAY208466 dihydrochloride
CAS:<p>WAY208466 dihydrochloride is a 5-HT6 receptor agonist (EC50=7.3 nM) with antidepressant and anxiolytic activity.</p>Formula:C17H20Cl2FN3O2SPurezza:98.43%Colore e forma:SolidPeso molecolare:420.33LY 302148
CAS:<p>LY 302148 , a 5-HT1F receptor agonist, inhibits neurogenic dural inflammation in guinea pigs. It has potential for migraine therapeutics.</p>Formula:C19H23FN4Purezza:98%Colore e forma:SolidPeso molecolare:326.41UCSF686
CAS:<p>UCSF686, a UCSF678 analog, lacks 5-HT5A potency but keeps affinity for 5-HT1A, 5-HT2B, 5-HT7, and serves as a control.</p>Formula:C14H19N3O2SColore e forma:SolidPeso molecolare:293.38ATC0065
CAS:<p>ATC0065 is a melanin-concentrating hormone receptor 1 antagonist with oral activity.</p>Formula:C25H29BrF3N5OColore e forma:SolidPeso molecolare:552.43ZM 169369
CAS:<p>ICI 169369, a 5-HT2/5-HT1C antagonist, can evoke endothelium-dependent relaxation in rabbit aorta.</p>Formula:C19H20N2SColore e forma:SolidPeso molecolare:308.44(R)-(+)-8-Hydroxy-DPAT hydrobromide
CAS:<p>5-HT1A serotonin receptor agonist</p>Formula:C16H26BrNOPurezza:98%Colore e forma:SolidPeso molecolare:328.29FG-5893
CAS:<p>FG-5893 is a 5-HT1A agonist and 5-HT2 antagonist with potential anxiolytic activity.</p>Formula:C27H29F2N3O2Purezza:98%Colore e forma:SolidPeso molecolare:465.53S 14063
CAS:<p>S 14063 is a potent 5-HT1A receptor antagonist devoid of beta-adrenoceptor blocking properties.</p>Formula:C22H29Cl2N3O2SColore e forma:SolidPeso molecolare:470.45Tertatolol
CAS:<p>Tertatolol is an effective antagonist of beta-adrenoceptor and 5-HT receptors.</p>Formula:C16H25NO2SPurezza:98%Colore e forma:SolidPeso molecolare:295.44Piclozotan
CAS:<p>Piclozotan (anhydrous), a 5-HT1A receptor agonist, demonstrated significant neuroprotective activity in a transient middle cerebral artery occlusion (t-MCAO)</p>Formula:C23H24ClN3O2Purezza:98.59%Colore e forma:SolidPeso molecolare:409.91Alniditan
CAS:<p>Alniditan is a receptors agonist of 5-HT1B/1D in HEK 293 cells (IC50: 1.7 and 1.3 nM). For 5-HT1B/1D receptors, the pKi values are 8.96 and 9.40, respectively.</p>Formula:C17H26N4OPurezza:98%Colore e forma:SolidPeso molecolare:302.415-HT2A receptor agonist-2
CAS:<p>Potent 5-HT2A receptor agonist-2 targets 5-HT2A/B/C with EC50 1.7, 0.58, 0.50 nM.</p>Formula:C20H21ClN2O3Colore e forma:SolidPeso molecolare:372.85AP-521 (Free base)
CAS:<p>AP-521, a 5-HT1A receptor antagonist, is used potentially for the treatment of anxiety.</p>Formula:C20H18N2O3SColore e forma:SolidPeso molecolare:366.43Bopindolol (malonate)
CAS:<p>Bopindolol is a non-selective β-adrenergic receptor antagonist.</p>Formula:C26H32N2O7Colore e forma:SolidPeso molecolare:484.549RS 39604
CAS:<p>potent and selective 5-HT4 antagonist</p>Formula:C26H37Cl2N3O6SPurezza:98%Colore e forma:SolidPeso molecolare:590.56Naronapride
CAS:<p>Naronapride (ATI-7505) is a potent agonist of the prokinetic 5-HT4receptor and can be used to study gastrointestinal disorders.</p>Formula:C27H41ClN4O5Colore e forma:SolidPeso molecolare:537.09Bifeprunox
CAS:Bifeprunox: potent antipsychotic, partial agonist at D2-like/5-HT1A receptors; treats schizophrenia.Formula:C24H23N3O2Purezza:98%Colore e forma:SolidPeso molecolare:385.46TMPPAA
CAS:<p>TMPPAA is an allosteric agonist of 5-HT3 receptor.</p>Formula:C15H21NO2Purezza:98%Colore e forma:SolidPeso molecolare:247.33Ziprasidone mesylate trihydrate
CAS:<p>Ziprasidone mesylate hydrate is an oral 5-HT/D2 antagonist with Ki: D2=4.8nM, 5-HT2A=0.42nM, 5-HT1A=3.4nM in rats.</p>Formula:C22H31ClN4O7S2Colore e forma:SolidPeso molecolare:563.085-HT7 agonist 1
CAS:<p>5-HT7 agonist 1 (4-[4-[(2-chlorophenyl)methyl]piperazin-1-yl]-1H-indole) is a selective agonist of 5-HT7 (IC50 = 222.93 nM).</p>Formula:C19H20ClN3Purezza:98.61%Colore e forma:SolidPeso molecolare:325.84Pruvanserin hydrochloride
CAS:<p>Pruvanserin hydrochloride (EMD 281014 HCl) is a selective 5-HT2A receptor antagonist, inhibits GTP-gamma-S accumulation and alleviates tactile allodynia.</p>Formula:C22H22ClFN4OPurezza:99.6%Colore e forma:SolidPeso molecolare:412.89Eplivanserin
CAS:<p>Eplivanserin (SR-46349) is an effective and selective antagonist of 5-HT2A receptor with a Kd of 1.14 nM and an IC50 value of 5.8 nM in rat cortical membrane.</p>Formula:C19H21FN2O2Purezza:97.04%Colore e forma:SolidPeso molecolare:328.38SB-737050A
CAS:<p>SB-737050A, a 5-HT antagonist, is used potentially for the treatment of schizophrenia.</p>Formula:C22H23ClN2O3S2Colore e forma:SolidPeso molecolare:463.01EMDT
CAS:<p>EMDT oxalate is a selective 5-HT6 agonist, and has antidepressant effects.</p>Formula:C15H22N2OPurezza:97.66% - 99.78%Colore e forma:SolidPeso molecolare:246.35GR 113808
CAS:<p>GR 113808 is a 5-HT4 receptor antagonist that inhibits 5-HT1B and 5-HT3 receptors and attenuates morphine-stimulated dopamine release in the rat striatum.</p>Formula:C19H27N3O4SPurezza:98.16%Colore e forma:SolidPeso molecolare:393.5PNU-142633
CAS:<p>PNU-142633: anti-migraine, selective 5-HT1D agonist, Ki=6 nM; >18,000 nM for 5-HT1B.</p>Formula:C24H30N4O3Purezza:98%Colore e forma:SolidPeso molecolare:422.52SB-221284
CAS:5-HT2C/2B receptor antagonistFormula:C16H14F3N3OSPurezza:98%Colore e forma:SolidPeso molecolare:353.36Adatanserin
CAS:<p>Adatanserin (WY 50324) is a mixed 5-HT1A receptor partial agonist and a 5-HT2A and 5-HT2C receptor antagonist.</p>Formula:C21H31N5OPurezza:99.33%Colore e forma:SolidPeso molecolare:369.5Alniditan dihydrochloride
CAS:<p>Alniditan dihydrochloride is a potent 5-HT1D agonist and migraine-abortive agent.</p>Formula:C17H28Cl2N4OColore e forma:SolidPeso molecolare:375.34TIK-301
CAS:<p>TIK-301 is a chlorinated melatonin derivative and a potent, high-affinity, and orally active melatonin MT1 and MT2 receptors agonist (Kis: 0.081 nM and 0.042 nM</p>Formula:C14H17ClN2O2Purezza:98%Colore e forma:SolidPeso molecolare:280.75LY 125180
CAS:LY 125180 is a serotonin antagonist.Formula:C18H24ClNOPurezza:98%Colore e forma:SolidPeso molecolare:305.84RS 56812 hydrochloride
CAS:<p>5-HT3 partial agonist</p>Formula:C18H22ClN3O2Purezza:98.62%Colore e forma:SolidPeso molecolare:347.84Iprindole
CAS:<p>Iprindole, a tricyclic indole antidepressant, is a dual weak inhibitor of noradrenaline and 5-HT uptake [1].</p>Formula:C19H28N2Purezza:99.54%Colore e forma:SolidPeso molecolare:284.44LY 334370 hydrochloride
CAS:5-HT1F receptor agonistFormula:C21H23ClFN3OPurezza:98%Colore e forma:SolidPeso molecolare:387.88Irindalone
CAS:<p>IrindaloneIrindalone is a potent serotonin (5-HT2) antagonist.</p>Formula:C24H29FN4OPurezza:98%Colore e forma:SolidPeso molecolare:408.51PNU-282987 S enantiomer hydrochloride
CAS:<p>(S)-PNU-282987, selective α7 nAChR agonist; Ki=26 nM (rat), weak on other receptors except 5-HT3; Ki=930 nM.</p>Formula:C14H18Cl2N2OPurezza:98%Colore e forma:SolidPeso molecolare:301.21
