recettore 5-HT
I recettori 5-HT, noti anche come recettori della serotonina, sono un gruppo di recettori accoppiati alle proteine G (GPCR) che mediano gli effetti della serotonina, un neurotrasmettitore coinvolto nella regolazione dell'umore, dell'ansia, del sonno, dell'appetito e di altri processi fisiologici. Questi recettori sono suddivisi in diversi sottotipi, ciascuno con funzioni e proprietà farmacologiche distinte. I modulatori dei recettori 5-HT sono ampiamente studiati per il loro ruolo nel trattamento della depressione, dei disturbi d'ansia e di altre condizioni neuropsichiatriche. Presso CymitQuimica, offriamo una gamma di modulatori dei recettori 5-HT di alta qualità per supportare la tua ricerca in neurofarmacologia, disturbi dell'umore e segnalazione GPCR.
Trovati 942 prodotti di "recettore 5-HT"
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Pimethixene maleate
CAS:<p>Pimethixene maleate (Pimetixene maleate) is a 5-HT2B receptor antagonist with sedative activity that can be used to study dry cough in children.</p>Formula:C23H23NO4SPurezza:99.55%Colore e forma:SolidPeso molecolare:409.5Ecopipam
CAS:<p>Ecopipam: orally active, selective dopamine D1/D5 antagonist (Ki: 1.2 nM/2.0 nM). 40x more selective over D2/D4/5-HT/α2a. For schizophrenia, obesity research.</p>Formula:C19H20ClNOPurezza:99.68%Colore e forma:SolidPeso molecolare:313.82PNU-282987 free base
CAS:<p>PNU-282987 is an α7 nAChR agonist (EC50=154 nM) and a 5-HT3 antagonist (IC50=4541 nM) for nervous system research.</p>Formula:C14H17ClN2OPurezza:99.64%Colore e forma:SolidPeso molecolare:264.75Adoprazine
CAS:<p>Adoprazine (SLV313) is a potential atypical antipsychotic bearing potent D2 receptor antagonist and 5-HT1A receptor agonist properties.</p>Formula:C24H24FN3O2Purezza:99.83%Colore e forma:SolidPeso molecolare:405.46Lesopitron
CAS:<p>Lesopitron: anxiolytic, 5-HT1A agonist, treats rodent anxiety, counters benzodiazepine withdrawal, low toxicity, no alcohol/barbiturate interaction.</p>Formula:C15H21ClN6Purezza:99.15% - 99.38%Colore e forma:SolidPeso molecolare:320.82Ricasetron
CAS:<p>Ricasetron (Brl 46470) is a 5-HT3 receptor antagonist with pro-axonal lysing properties and is used in the study of anxiety disorders and anxiety disorders.</p>Formula:C19H27N3OPurezza:99.52%Colore e forma:SolidPeso molecolare:313.44Anpirtoline hydrochloride
CAS:<p>Anpirtoline hydrochloride (D-16949 hydrochloride) is a 5-HT1B receptor agonist and 5-HT3 receptor antagonist used in the study of dyskinesia.</p>Formula:C10H14Cl2N2SPurezza:>99.99% - >99.99%Colore e forma:SolidPeso molecolare:265.20Rilapine
CAS:<p>Rilapine (Rilapinum) is an antipsychotic compound that shows high affinity for 5-HT6 receptors and can be used to study neurological disorders.</p>Formula:C22H20ClN3Purezza:97.76% - 99.20%Colore e forma:SolidPeso molecolare:361.87Sarizotan HCl
CAS:<p>Sarizotan HCl (EMD 128130 HCl) is a 5-HT1A receptor and dopamine receptor agonist and an hERG channel inhibitor used in Parkinson;s disease research.</p>Formula:C22H22ClFN2OPurezza:96%Colore e forma:SolidPeso molecolare:384.87Agomelatine hydrochloride
CAS:<p>Agomelatine HCl is a MT1/MT2 receptor agonist (Ki: 0.1-0.27 nM) and a 5-HT2C antagonist (pKi: 6.2-6.4).</p>Formula:C15H18ClNO2Purezza:99.57%Colore e forma:SolidPeso molecolare:279.76R 59-022 hydrochloride
CAS:<p>R 59-022 hydrochloride is a 5-HT antagonist, PKC activator, DGK inhibitor (IC50: 2.8 µM), and modulates lipid production in platelets and neutrophils.</p>Formula:C27H27ClFN3OSPurezza:97.7%Colore e forma:SolidPeso molecolare:496.04DA-6886
CAS:<p>DA-6886 is a 5-HT4 agonist, relaxes rat oesophagus, with 1000x selectivity over hERG channels, pIC50: 4.3.</p>Formula:C19H28Cl2N6O2Purezza:99.28% - 99.91%Colore e forma:SolidPeso molecolare:443.37Fananserin
CAS:<p>Fananserin: Oral 5-HT2A antagonist (Ki=0.37 nM, rat), blocks human D4 receptor (Ki=2.93 nM).</p>Formula:C23H24FN3O2SPurezza:99.88%Colore e forma:SolidPeso molecolare:425.52cis-Urocanic acid
CAS:<p>cis-Urocanic acid ((E)-Urocanic acid) is a 5-HT2A receptor agonist (Kd: 4.6 nM).</p>Formula:C6H6N2O2Purezza:99.81%Colore e forma:SolidPeso molecolare:138.12Repinotan
CAS:<p>Repinotan (BAY x 3702 free base) is a 5-HT1A receptor agonist used in acute ischemic stroke studies.</p>Formula:C21H24N2O4SPurezza:99%Colore e forma:SolidPeso molecolare:400.49NAS181
CAS:<p>rat 5-HT1B receptor antagonist</p>Formula:C21H34N2O10S2Purezza:98%Colore e forma:SolidPeso molecolare:538.63LY320954
CAS:<p>LY320954 is an antagonist of 5-HT2A receptor.</p>Formula:C21H26N4O3Purezza:98%Colore e forma:SolidPeso molecolare:382.46LY-426965
CAS:<p>LY-426965 is a selective, potent, orally bioavailable 5-HT1A antagonist.</p>Formula:C28H38N2O2Colore e forma:SolidPeso molecolare:434.61UNC9994
CAS:<p>UNC9994 is a β-arrestin-biased dopamine D₂ receptor agonist (β-arrestin EC50 = 50 nM; Emax = 97%) with robust in vivo antipsychotic drug-like activities.</p>Formula:C21H22Cl2N2OSColore e forma:SolidPeso molecolare:421.38SB 258719
CAS:<p>SB 258719 is a selective antagonist of 5-HT7 receptor with pKi of 7.5.</p>Formula:C18H30N2O2SPurezza:99.73%Colore e forma:SolidPeso molecolare:338.51Wf-516
CAS:<p>Wf-516 is a 5-HT reuptake inhibitor (Kis: 5 nM and 40 nM for 5-HT1A receptor and 5-HT2A receptor in humans, respectively), and with potent antidepressant</p>Formula:C25H25Cl2N3O4Purezza:98%Colore e forma:SolidPeso molecolare:502.39Befiradol
CAS:<p>Befiradol (NLX-112) is an agonist of 5-HT1A receptor.</p>Formula:C20H22ClF2N3OColore e forma:SolidPeso molecolare:393.865-HT2A antagonist 1
CAS:<p>5-HT2A antagonist 1, from US5728835A & JP 1007727, may treat gastrointestinal and circulatory issues.</p>Formula:C26H28N4O2Purezza:98%Colore e forma:SolidPeso molecolare:428.53Osemozotan Free Base
CAS:<p>Osemozotan Free Base is a 5-HT(1A) receptor agonist.</p>Formula:C19H21NO5Colore e forma:SolidPeso molecolare:343.37Mesembrine
CAS:<p>Mesembrine is an alkaloid, a 5-HT transporter inhibitor (K i 1.4 nM), and inhibits PDE4B (IC50 7.8 μM).</p>Formula:C17H23NO3Colore e forma:SolidPeso molecolare:289.37Robalzotan
CAS:<p>Robalzotan is a selective 5-HT1A receptor antagonist.</p>Formula:C18H23FN2O2Purezza:98%Colore e forma:SolidPeso molecolare:318.39Facinicline hydrochloride
CAS:<p>Facinicline hydrochloride (RG3487) is both a novel nicotinic alpha-7 receptor (alpha7nAChR) partial agonist (Ki = 6 nM) and an antagonist of 5-HT3(Ki = 1.2 nM).</p>Formula:C15H19ClN4OPurezza:98.70%Colore e forma:SolidPeso molecolare:306.79NAS-181
CAS:<p>NAS-181 is a potent and selective rat 5-hydroxytryptamine 1B (r5-HT1B) antagonist (Ki: 47 nM).NAS-181 enhances the accumulation of 5-HTP in rat brain regions.</p>Formula:C20H30N2O7SColore e forma:SolidPeso molecolare:442.53Cyanopindolol fumarate
CAS:<p>Cyanopindolol fumarate is a 5-HT receptor antagonist [1].</p>Formula:C16H21N3O2C4H4O4Colore e forma:SolidPeso molecolare:345.45-HT2C agonist-3 free base
CAS:<p>5-HT2C agonist-3 ((+)-19) free base, a selective 5-HT2C agonist (EC50: 24 nM, Ki: 78 nM), exhibits antipsychotic drug-like activity and inhibits Amphetamine-</p>Formula:C19H22FNO2Purezza:98%Colore e forma:SolidPeso molecolare:315.38(S)-Bexicaserin
CAS:<p>(S)-Bexcaserin (compound 2) serves as a 5-HT2C receptor agonist, presenting research possibilities in obesity and psychiatric disorders [1].</p>Formula:C15H19F2N3OPurezza:98%Colore e forma:SolidPeso molecolare:295.33Nemonapride
CAS:<p>Nemonapride is a dopamine D2-like receptor antagonist.</p>Formula:C21H26ClN3O2Purezza:98%Colore e forma:SolidPeso molecolare:387.95-HT2A&5-HT2C agonist-1
CAS:<p>5-HT2A&5-HT2C agonist-1 (Example 2) is a dual-acting agent targeting the 5-HT2A and 5-HT2C receptors with respective IC50 values of 196 nM and 0.9 nM.</p>Formula:C14H20N2OPurezza:98%Colore e forma:SolidPeso molecolare:232.32CP-122288
CAS:<p>CP-122288: potent, selective 5-HT1B/D/F agonist; inhibits plasma protein extravasation, neurogenic inflammation.</p>Formula:C16H23N3O2SPurezza:98%Colore e forma:SolidPeso molecolare:321.44Gentisein
CAS:<p>Gentisein (NSC-329491), a primary metabolite of Mangiferin, exhibits significant inhibition of serotonin uptake, demonstrating potency with an IC50 value of 4.7</p>Formula:C13H8O5Purezza:96.89%Colore e forma:SolidPeso molecolare:244.2MIN-117
CAS:<p>MIN-117, a SSRI/5-HT receptor antagonist, is potentially used for the treatment of depression.</p>Formula:C25H26Cl3N3O4Purezza:98%Colore e forma:SolidPeso molecolare:538.85Dothiepin
CAS:<p>Dothiepin (Dosulepin; Dothep), an antidepressant with sedative/anxiolytic properties, preferentially inhibits noradrenaline over serotonin uptake, enhancing</p>Formula:C19H21NSPurezza:98%Colore e forma:SolidPeso molecolare:295.44L-772,405
CAS:<p>L-772,405 is a highly selective agonists of h5-HT(1D) receptor.</p>Formula:C26H31FN6OPurezza:98%Colore e forma:SolidPeso molecolare:462.564-Chloro-L-phenylalanine
CAS:<p>4-Chloro-L-phenalanine (L-PCPA) is an inhibitor of 5-HT biosynthesis and a non-specific antagonist of tryptophan hydroxylases (TPH1 and TPH2).</p>Formula:C9H10ClNO2Purezza:99.76% - 99.96%Colore e forma:SolidPeso molecolare:199.635-HT2 agonist-1
CAS:<p>Compound 24, a 5-HT2 agonist-1, selectively activates 5-HT2A, 5-HT2B, and 5-HT2C receptors with IC50 values of 10 nM, 8.3 nM, and 1.6 nM, respectively.</p>Formula:C19H23ClN2O2Purezza:98%Colore e forma:SolidPeso molecolare:346.85DU-125530
CAS:<p>DU-125530 is a 5-HT1A receptor antagonist.</p>Formula:C23H26ClN3O5SColore e forma:SolidPeso molecolare:491.99Velusetrag
CAS:<p>Velusetrag(TD-5108), a potent 5-HT4 agonist, is in development for gastroparesis, constipation, and IBS.</p>Formula:C25H36N4O5SColore e forma:SolidPeso molecolare:504.64LY108742
CAS:<p>LY108742 is an antagonist of 5-HT2.</p>Formula:C21H28N2O3Purezza:98%Colore e forma:SolidPeso molecolare:356.46GR-127935
CAS:<p>GR-127935 is a potent and selective 5-HT1B/1D receptor antagonist.</p>Formula:C29H31N5O3Colore e forma:SolidPeso molecolare:497.59GYKI-46903 HCl
CAS:<p>GYKI-46903 is a noncompetitive 5-HT3 receptor antagonist.</p>Formula:C17H21ClFNO2Colore e forma:SolidPeso molecolare:325.81PZ-1190
CAS:<p>PZ-1190, a multitarget ligand for serotonin and dopamine receptors, exhibits potential antipsychotic activity in rodents [1].</p>Formula:C27H30N4O2S2Purezza:98%Colore e forma:SolidPeso molecolare:506.68(±)-Fabesetron hydrochloride
CAS:<p>FK1052 hydrochloride is a potent 5-HT3 and 5-HT4 receptor dual antagonist.</p>Formula:C18H20ClN3OPurezza:98%Colore e forma:SolidPeso molecolare:329.82Flesinoxan
CAS:<p>Flesinoxan is a hypotensive agent and is an effective, high affinity, and selective 5-hydroxytryptamine1A receptor agonist (EC50: 24 nM).</p>Formula:C22H26FN3O4Colore e forma:SolidPeso molecolare:415.46(S)-Renzapride
<p>(S)-Renzapride (BRL 24924), 5-HT4 agonist (Ki 115 nM), 5HT2b/5HT3 antagonist, for C-IBS study.</p>Formula:C16H22ClN3O2Colore e forma:SolidPeso molecolare:323.825-HT2 agonist-1 free base
CAS:<p>Compound 24 (5-HT2 agonist-1 free base) is a potent agonist for 5-HT2A, 5-HT2B, and 5-HT2C receptors, exhibiting IC50 values of 10 nM, 8.3 nM, and 1.6 nM,</p>Formula:C19H22N2O2Purezza:98%Colore e forma:SolidPeso molecolare:310.39
