recettore 5-HT
I recettori 5-HT, noti anche come recettori della serotonina, sono un gruppo di recettori accoppiati alle proteine G (GPCR) che mediano gli effetti della serotonina, un neurotrasmettitore coinvolto nella regolazione dell'umore, dell'ansia, del sonno, dell'appetito e di altri processi fisiologici. Questi recettori sono suddivisi in diversi sottotipi, ciascuno con funzioni e proprietà farmacologiche distinte. I modulatori dei recettori 5-HT sono ampiamente studiati per il loro ruolo nel trattamento della depressione, dei disturbi d'ansia e di altre condizioni neuropsichiatriche. Presso CymitQuimica, offriamo una gamma di modulatori dei recettori 5-HT di alta qualità per supportare la tua ricerca in neurofarmacologia, disturbi dell'umore e segnalazione GPCR.
Trovati 942 prodotti di "recettore 5-HT"
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Frovatriptan
CAS:<p>Frovatriptan, potent 5-HT 1B/D agonist, shows high cerebroselectivity and efficacy for migraine with aura.</p>Formula:C14H17N3OColore e forma:SolidPeso molecolare:243.3YM348
CAS:<p>YM348 is an effective and orally active 5-HT2C receptor agonist. YM348 also shows a high affinity for the cloned human 5-HT2C receptor (Ki: 0.89 nM).</p>Formula:C14H17N3OPurezza:98%Colore e forma:SolidPeso molecolare:243.35-HT2C agonist-3
CAS:<p>5-HT2C agonist-3 ((+)-19), a selective 5-HT2C agonist (EC 50: 24 nM, Ki: 78 nM), exhibits antipsychotic-like activity by blocking amphetamine-induced</p>Formula:C19H23ClFNO2Purezza:98%Colore e forma:SolidPeso molecolare:351.84Capeserod HCl
CAS:<p>Capeserod HCl, a 5-hydroxytriptamine 4 (5-HT4) receptor agonist, is used potentially for the treatment of Alzheimer's disease.</p>Formula:C23H26Cl2N4O4Purezza:98%Colore e forma:SolidPeso molecolare:493.38Abaperidone
CAS:<p>Abaperidone is an atypical antipsychotic, antagonizes 5-HT2A (IC50=6.2 nM) and D2 receptors (IC50=17 nM), reduces hsp70 mRNA in rat brains.</p>Formula:C25H25FN2O5Purezza:98.22%Colore e forma:SolidPeso molecolare:452.47Indeloxazine hydrochloride
CAS:<p>Indeloxazine HCl: Serotonin releaser, NE reuptake inhibitor, NMDA antagonist; antidepressant that boosts acetylcholine in rats.</p>Formula:C14H18ClNO2Purezza:98%Colore e forma:SolidPeso molecolare:267.75UNC9994 hydrochloride
CAS:<p>UNC9994 hydrochloride is a selective β-arrestin-biased D2R agonist, Ki of 79 nM, that stimulates β-arrestin and modulates cAMP.</p>Formula:C21H23Cl3N2OSColore e forma:SolidPeso molecolare:457.84GR 127935 hydrochloride
CAS:<p>5-HT1B/1D receptor antagonist</p>Formula:C29H32ClN5O3Purezza:98%Colore e forma:SolidPeso molecolare:534.05FPPQ
CAS:<p>FPPQ blocks 5-HT3 and 5-HT6 receptors (Ki: 0.9 & 3 nM) and may improve psychosis and cognition.</p>Formula:C21H19FN4O2SColore e forma:SolidPeso molecolare:410.46GR 125487 sulfamate
CAS:<p>GR 125487 sulfamate is a 5-HT4 receptor antagonist.</p>Formula:C19H29FN4O8S2Purezza:98%Colore e forma:SolidPeso molecolare:524.58SB 649915
CAS:SB 649915 is a serotonin reuptake inhibitor and 5-HT1A and 5-HT1B receptor antagonist.Formula:C26H29N3O3Colore e forma:SolidPeso molecolare:431.53NAD 299 hydrochloride
CAS:<p>Selective, high affinity 5-HT1A receptor antagonist</p>Formula:C18H24ClFN2O2Purezza:98%Colore e forma:SolidPeso molecolare:354.855-HT3 antagonist 1
CAS:<p>5-HT3 antagonist 1 is a potent and selective antagonist of 5-HT3 receptor.</p>Formula:C22H27N5OPurezza:98%Colore e forma:SolidPeso molecolare:377.48R-96544
CAS:<p>R-96544 is an orally active antagonist of the 5-HT2A receptor that has demonstrated the ability to inhibit platelet aggregation in vitro [1].</p>Formula:C22H30ClNO3Colore e forma:SolidPeso molecolare:391.935-HT2A receptor agonist-3
CAS:<p>5-HT2A receptor agonist-3 represents the highest selectivity for the human 5-HT2A receptor currently identified, exhibiting a K i of 2.5 nM.</p>Formula:C21H26BrNO3Purezza:98%Colore e forma:SolidPeso molecolare:420.34Brilaroxazine
CAS:<p>Brilaroxazine (RP5063): multimodal dopamine/5-HT modulator, partial agonist at D2/D3/D4, 5-HT1A/2A, and antagonist at 5-HT2B/7.</p>Formula:C22H25Cl2N3O3Purezza:99.36%Colore e forma:SolidPeso molecolare:450.36LY 53857
CAS:<p>LY 53857 is a potent and selective antagonist of 5-HT2 serotonin receptor.</p>Formula:C27H36N2O7Colore e forma:SolidPeso molecolare:500.5925-HT3-In-1
CAS:<p>5-HT3-In-1 (compound example 8) exhabits with 5-HT3 inhibition activity.</p>Formula:C16H21ClN4O3Purezza:98%Colore e forma:SolidPeso molecolare:352.82PNU109291
CAS:<p>PNU109291, a potent and selective agonist of the 5-HT1D receptor, effectively mitigates dural plasma extravasation induced by trigeminal ganglion stimulation.</p>Formula:C24H31N3O3Purezza:98%Colore e forma:SolidPeso molecolare:409.52Gepirone
CAS:<p>Gepirone is a 5-HT1A receptor agonist belonging to the buspirone family. Gepirone HCl possesses greater selectivity for the 5-HT1A receptor than SSRIs.</p>Formula:C19H29N5O2Purezza:99.35% - 99.89%Colore e forma:SolidPeso molecolare:359.472-Methyl-5-HT
CAS:<p>2-Methyl-5-HT (2-Methyl-5-hydroxytryptamine) is a potent and selective 5-HT3 receptor agonist with anti-depressive-like effects.</p>Formula:C11H14N2OPurezza:97.18%Colore e forma:SolidPeso molecolare:190.24Didesmethyl cariprazine
CAS:<p>Didesmethyl cariprazine, Cariprazine's active metabolite, treats schizophrenia/bipolar with D3/D2 affinity; half-life 1-3 weeks.</p>Formula:C19H28Cl2N4OPurezza:99.52%Colore e forma:SolidPeso molecolare:399.36SB 216641 hydrochloride
CAS:<p>SB 216641 hydrochloride (SB-216641A) is a 5-HT1B/D receptor antagonist with anxiolytic properties.</p>Formula:C28H31ClN4O4Purezza:98.06% - 99.23%Colore e forma:SolidPeso molecolare:523.02Osemozotan HCl
CAS:<p>Osemozotan is a 5-HT1A receptor agonist potentially for the treatment of generalized anxiety disorder.</p>Formula:C19H22ClNO5Purezza:98.87% - 99.63%Colore e forma:SolidPeso molecolare:379.84WAY-607695
CAS:<p>WAY-607695 is a potential 5-HT1A receptor agonist.</p>Formula:C13H12FNO2Purezza:99.82%Colore e forma:SolidPeso molecolare:233.24Lumateperone
CAS:<p>Lumateperone (ITI 722) is a 5HT2A receptor antagonist and a dopamine receptor phosphoprotein modulator (DPPM).</p>Formula:C24H28FN3OPurezza:99.68% - 99.91%Colore e forma:SolidPeso molecolare:393.5SB-616234-A
CAS:<p>SB-616234-A is a selective and orally bioavailable antagonist of 5-HT1B receptor, with anxiolytic and antidepressant activity.</p>Formula:C32H36ClN5O3Purezza:99.72%Colore e forma:SolidPeso molecolare:574.115-HT6/5-HT2AR antagonist-1
<p>Potent 5-HT6/5-HT2A receptors dual antagonist with K i of 11 nM & 39 nM.</p>Formula:C21H26N6SColore e forma:SolidPeso molecolare:394.54Tiprenolol hydrochloride
CAS:<p>Tiprenolol hydrochloride is a β-adrenoceptor (β-adrenoceptor) antagonist. This compound is effective in eliminating ventricular arrhythmias in dogs caused by intravenous administration of adrenaline, following inhalation of halothane.</p>Formula:C13H22ClNO2SColore e forma:SolidPeso molecolare:291.84ASP-2205
CAS:<p>ASP-2205, a 5-HT2C receptor agonist (human 5-HT2C receptor, EC50=0.85 nM; rat 5-HT2C receptor, EC50=2.5 nM), enhances the urethral closure reflex mediated by the genital nerve, thereby preventing urinary incontinence.</p>Formula:C19H28N2OColore e forma:SolidPeso molecolare:300.44Flucopride
CAS:<p>Flucopride (Compound 4a) acts as an acetylcholinesterase inhibitor (AChE) with an IC50 value of 24 nM and serves as a partial agonist for the human 5-HT4 receptor (5-HT4R) with a Ki of 9.6 nM for (h)5-HT4R. It promotes non-amyloidogenic processing of APP in COS-7 cells transiently expressing (h)5-HT4R with an EC50 of 23.0 nM. Flucopride is also likely to exhibit significant gastrointestinal tract (GIT) penetration and blood-brain barrier (BBB) permeability, as determined in PAMPA experiments.</p>Formula:C22H33FN2O2Colore e forma:SolidPeso molecolare:376.51Sulamserod hydrochloride
CAS:<p>Sulamserod hydrochloride is a 5-HT4 receptor antagonist. It is utilized in research related to gastrointestinal disorders.</p>Formula:C19H29Cl2N3O5SColore e forma:SolidPeso molecolare:482.42Rodatristat
CAS:<p>Rodatristat is an effective tryptophan hydroxylase 1 and TPH2 inhibitor (IC50s: 33 nM and 7 nM, respectively).</p>Formula:C27H27ClF3N5O3Purezza:98%Colore e forma:SolidPeso molecolare:561.98Elzasonan hydrochloride
CAS:<p>Elzasonan hydrochloride is a serotonin 1B and serotonin 1D receptor antagonist. It is utilized in the study of depression.</p>Formula:C22H24Cl3N3OSColore e forma:SolidPeso molecolare:484.87Tipindole
CAS:<p>Tipindole is a serotonin antagonist utilized in research related to depression.</p>Formula:C16H20N2O2SColore e forma:SolidPeso molecolare:304.41AAZ-A 154 mesylate
CAS:<p>AAZ-A 154 mesylate mesylate is a selective, competitive, and non-hallucinogenic antagonist of 5-HT2AR. It enhances neuronal growth in rodents and produces enduring beneficial behavioral effects.</p>Formula:C15H24N2O4SColore e forma:SolidPeso molecolare:328.4325B-NBOH hydrochloride
CAS:<p>25B-NBOH hydrochloride is a phenethylamine that exhibits high affinity for serotonin (5-HT) receptors 5-HT2A and 5-HT2C, with pKi values of 8.3 and 9.4, respectively.</p>Formula:C17H21BrClNO3Colore e forma:SolidPeso molecolare:402.711D3/5-HT receptor modulator-1
CAS:<p>D3/5-HT receptor modulator-1 (compound 5i) is a selective antagonist of the dopamine D3 and 5-HT2A receptors, and a partial agonist at the 5-HT1A receptor. It exhibits Ki values of 4.5 nM, 11.9 nM, and 15.3 nM for the dopamine D3, 5-HT2A, and 5-HT1A receptors respectively. The compound shows lower affinity for the dopamine D2 receptor, 5-HT2C receptor, and hERG channel. D3/5-HT receptor modulator-1 possesses atypical antipsychotic properties.</p>Formula:C24H29N3O2Colore e forma:SolidPeso molecolare:391.506Etoperidone
CAS:<p>Etoperidone is an antidepressant that acts as an orally active reuptake inhibitor for serotonin (serotonin) and noradrenaline (nor-adrenaline). It demonstrates specific binding affinities (Kd) for several receptors: 36 nM at the 5-HT2 receptor, 38 nM at the α1-adrenergic receptor (α1-adrenergic receptor), 85 nM at the 5-HT1A receptor, and 570 nM at the α2-adrenergic receptor (α2-adrenergic receptor).</p>Formula:C19H28ClN5OColore e forma:SolidPeso molecolare:377.91AM9405
<p>AM9405: peripheral CB1/5-HT3 agonist, suppresses gut motility, relieves GI disorder symptoms in mice.</p>Formula:C24H33BrN2O2Purezza:98%Colore e forma:SolidPeso molecolare:461.44SB 258741 hydrochloride
<p>SB 258741 hydrochloride is a potent antagonist of the 5-HT 7 receptor, designed specifically for studying schizophrenia [1].</p>Formula:C19H31ClN2O2SColore e forma:SolidPeso molecolare:386.985-IAI hydrochloride
CAS:<p>5-IAI hydrochloride is a psychoactive analog of para-iodoamphetamine. 5-IAI hydrochloride significantly reduces serotonin uptake sites and hippocampal serotonin levels in rats.</p>Formula:C9H11ClINColore e forma:SolidPeso molecolare:295.548Mesulergine hydrochloride
CAS:<p>5-HT2A and 2C receptor antagonist</p>Formula:C18H27ClN4O2SPurezza:98%Colore e forma:SolidPeso molecolare:398.95Rodatristat ethyl
CAS:<p>Rodatristat ethyl is an oral TPH1 inhibitor reducing 5-HT levels & lowering PAH at low doses.</p>Formula:C29H31ClF3N5O3Purezza:98%Colore e forma:SolidPeso molecolare:590.045-HT7R antagonist 3
CAS:<p>Compound 6.4, also known as 5-HT7R antagonist 3, is a selective antagonist of the 5-HT7R with a Ki of 8 nM. It exhibits significantly less affinity towards D2R, 5-HT1AR, and 5-HT2AR with Ki values of 511 nM, 8930 nM, and 5786 nM, respectively. In mice, 5-HT7R antagonist 3 demonstrates anti-depressant and anti-anxiety activities.</p>Formula:C30H33FN4O3Colore e forma:SolidPeso molecolare:516.61U92016A hydrochloride
CAS:<p>U92016A hydrochloride: potent, orally active 5-HT1A agonist, metabolically stable, high intrinsic activity, Ki=0.2 nM.</p>Formula:C19H26ClN3Colore e forma:SolidPeso molecolare:331.89Befiradol hydrochloride
CAS:<p>Befiradol HCl (NLX-112) is a selective 5-HT1A receptor agonist with anxiolytic effects and prevents ATXN3 aggregation.</p>Formula:C20H23Cl2F2N3OPurezza:99.1%Colore e forma:SolidPeso molecolare:430.325-HT1A antagonist 1
<p>Compound 6f is a potent, selective 5-HT1A receptor blocker (Ki: 35 nM), useful in CNS disorder research.</p>Formula:C23H29ClN6O2Colore e forma:SolidPeso molecolare:456.97SB 243213 dihydrochloride
CAS:<p>SB 243213 dihydrochloride is an orally active, selective and high-affinity antagonist of 5-hydroxytryptamine (5-HT)2C receptor(pKi of 9.37 and a pKb of 9.8 for</p>Formula:C22H21Cl2F3N4O2Purezza:98%Colore e forma:SolidPeso molecolare:501.33AAZ-A 154
CAS:<p>AAZ-A 154 is a selective, competitive, and non-hallucinogenic antagonist of the 5-HT2AR. It promotes neuronal growth in rodents and results in lasting beneficial behavioral effects.</p>Formula:C14H20N2OColore e forma:SolidPeso molecolare:232.32
