recettore 5-HT
I recettori 5-HT, noti anche come recettori della serotonina, sono un gruppo di recettori accoppiati alle proteine G (GPCR) che mediano gli effetti della serotonina, un neurotrasmettitore coinvolto nella regolazione dell'umore, dell'ansia, del sonno, dell'appetito e di altri processi fisiologici. Questi recettori sono suddivisi in diversi sottotipi, ciascuno con funzioni e proprietà farmacologiche distinte. I modulatori dei recettori 5-HT sono ampiamente studiati per il loro ruolo nel trattamento della depressione, dei disturbi d'ansia e di altre condizioni neuropsichiatriche. Presso CymitQuimica, offriamo una gamma di modulatori dei recettori 5-HT di alta qualità per supportare la tua ricerca in neurofarmacologia, disturbi dell'umore e segnalazione GPCR.
Trovati 942 prodotti di "recettore 5-HT"
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4-Butyl-α-agarofuran
CAS:<p>4-Butyl-alpha-agarofuran, a Gharu-wood derivative, is an anxiolytic, antidepressant, and aids neurological research.</p>Formula:C18H30OColore e forma:SolidPeso molecolare:262.43Oxatomide
CAS:<p>Oxatomide: Dual H1/P2X7 antagonist, antihistamine, anti-allergic, treats immune diseases, IC50: 0.95 μM (P2X7), 0.43 μM (5-HT).</p>Formula:C27H30N4OPurezza:98.82% - 99.72%Colore e forma:White PowderPeso molecolare:426.552-Methyl-N,N-dimethyltryptamine
CAS:<p>2-Methyl-N,N-dimethyltryptamine (2,N,N-TMT, compound 15) exhibits binding affinity for the serotonin (5-HT) receptor, with a pA2 value of 6.04. It plays a significant role in neurological disease research.</p>Formula:C13H18N2Colore e forma:SolidPeso molecolare:202.3Dipentylone hydrochloride
CAS:<p>Dipentylone hydrochloride (Bk-dmbdp HCl) is a psychoactive synthetic cathinone and sympathomimetic stimulant. Its inhibitory activity towards the dopamine transporter (IC50=0.233µM) is tenfold higher than that towards NET and SERT, inhibiting dopamine uptake and stimulating locomotor activity in mice.</p>Formula:C14H20ClNO3Purezza:99.94%Colore e forma:SolidPeso molecolare:285.77Naratriptan D3 Hydrochloride
CAS:Naratriptan D3 Hydrochloride is the deuterium labeled Naratriptan, is a selective agonist of 5-HT1 receptor subtype.Formula:C17H26ClN3O2SPurezza:98%Colore e forma:SolidPeso molecolare:374.946-Fluoro-N,N-diethyltryptamine
CAS:<p>6-Fluoro-N,N-diethyltryptamine (6-F-DET) exhibits affinity for the 5-HT2A receptor.</p>Formula:C14H19FN2Colore e forma:SolidPeso molecolare:234.3125N-NBOMe hydrochloride
CAS:<p>25N-NBOMe hydrochloride is a derivative of 2C-N and acts as an agonist for the 5-HT2A and 5-HT2C receptors, with Ki values of 0.144 nM and 1.06 nM, respectively. It has minimal effect on the release of preloaded neurotransmitters from recombinant dopamine, serotonin, and norepinephrine transporters.</p>Formula:C18H23ClN2O5Colore e forma:SolidPeso molecolare:382.84DSP-1053
CAS:<p>Dsp-1053 is a powerful SERT (Ki=1.02 nM) inhibitor with partial 5-HT1A receptor (Ki=5.05 nM) agonizing activity.</p>Formula:C26H32BrNO4Purezza:98%Colore e forma:SolidPeso molecolare:502.44LY-426965 hydrochloride
CAS:LY-426965 hydrochloride is a bioactive chemical.Formula:C28H39ClN2O2Colore e forma:SolidPeso molecolare:471.07Fabesetron
CAS:<p>Fabesetron (FK1052): oral dual antagonist for 5-HT3/5-HT4 receptors. Aids in managing acute and delayed chemo-induced emesis.</p>Formula:C18H19N3OColore e forma:SolidPeso molecolare:293.37AL 34662
CAS:<p>AL 34662 is a selective and potent 5-HT2A receptor agonist with IC50s of 0.77 nM and 1.5 nM for rat and human 5-HT2 receptors, respectively.AL 34662 is also a</p>Formula:C10H13N3OPurezza:99.77%Colore e forma:SolidPeso molecolare:191.23Jatrorrhizine hydroxide
CAS:<p>Jatrorrhizine hydroxide: alkaloid from Coptis chinensis; neuroprotective, antimicrobial, antiplasmodial, antioxidant; AChE inhibitor, affects 5-HT/NE uptake.</p>Formula:C20H21NO5Colore e forma:SolidPeso molecolare:355.385-HT5AR/5-HT6R ligand-1
<p>5-HT5AR/5-HT6R ligand-1 (Compound PP10) is a ligand for serotonin receptors, exhibiting high affinity for the 5-HT5A and 5-HT6 receptors with Ki values of 59 nM and 96 nM, respectively. It possesses some antiproliferative activity against tumor cells and can be utilized in cancer research.</p>Formula:C25H30N4O2SColore e forma:SolidPeso molecolare:450.6SB 258585
CAS:<p>SB 258585: Selective 5-HT6 antagonist, binds human receptors, used in cognitive and antipsychotic assays.</p>Formula:C18H22IN3O3SPurezza:99.8%Colore e forma:SoildPeso molecolare:487.36Tetrahydro-β-carboline
CAS:<p>Compound Fr12161, with CAS No. 16502-01-5, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound Fr12161 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.</p>Formula:C11H12N2Purezza:96.31%Colore e forma:Tan SolidPeso molecolare:172.22645-MeO-pyr-T
CAS:<p>5-MeO-pyr-T (5-Methoxy pyrrolidinyltryptamine) acts as a 5-HT1AR agonist, exhibiting Ki values of 0.577 μM and 373 μM for 5-HT1AR and 5-HT2AR, respectively. It inhibits the reuptake of 5-HT and triggers its release. Additionally, 5-MeO-pyr-T can induce reduced motor activity.</p>Formula:C15H20N2OColore e forma:SolidPeso molecolare:244.33Antipsychotic agent-2
<p>Compound 11: potent antipsychotic, binds 5-HT1A/2A/2C, D2, H1 receptors; K is 56.6-1140 nM, BBB permeable.</p>Formula:C22H26FN5OColore e forma:SolidPeso molecolare:395.47(Iso)-Landipirdine
CAS:<p>(Iso)-Landipirdine((Iso)-RO5025181) is a selective and potent 5-HT6R antagonist.</p>Formula:C18H19FN2O3SPurezza:98.50%Colore e forma:SoildPeso molecolare:362.42Pellotine
CAS:<p>Pellotine is an alkaloid isolated from Lophophora. It acts as an inverse agonist of the 5-HT7 receptor (5-HT7 receptor), with an EC50 of 291 nM. Pellotine shows strong affinity for the 5-HT1DR and 5-HT6R, with Ki values of 117 nM and 170 nM, respectively. Additionally, Pellotine reduces intracellular cAMP levels, thereby decreasing neuronal excitability and neurotransmitter release.</p>Formula:C13H19NO3Colore e forma:SolidPeso molecolare:237.2955-HT6R antagonist 6
<p>5-HT6R antagonist 6 (Compound PP15) exhibits high affinity and selectivity for the 5-HT6R receptor, with a Ki of 42 nM. It demonstrates weak antiproliferative activity on tumor cells and low toxicity toward normal cells. 5-HT6R antagonist 6 is applicable in tumor research.</p>Formula:C24H26N4O2SColore e forma:SolidPeso molecolare:434.55pCPA methyl ester hydrochloride
CAS:<p>pCPA methyl ester HCl inhibits tryptophan hydroxylase, 5-HT synthesis, crosses blood-brain barrier, lowers central 5-HT.</p>Formula:C10H13Cl2NO2Purezza:99.73% - 99.88%Colore e forma:SolidPeso molecolare:250.12Galanin (1-15) (porcine, rat)
CAS:<p>N-terminal galanin fragment used to mediate central cardiovascular effects</p>Formula:C72H105N19O20Purezza:98%Colore e forma:SolidPeso molecolare:1556.72Quetiapine-d4 fumarate
CAS:<p>Deuterium-labeled Quetiapine fumarate; an antidepressant and anxiolytic 5-HT agonist, dopamine antagonist.</p>Formula:C25H29N3O6SPurezza:98%Colore e forma:SolidPeso molecolare:503.614-fluoro MBZP
CAS:<p>4-fluoro MBZP is a novel psychoactive substance in the phenylpiperazine class, utilized for studies on the 5-HT2 receptors in the central nervous system.</p>Formula:C12H17FN2Colore e forma:SolidPeso molecolare:208.28Mirtazapine N-oxide
CAS:<p>Mirtazapine N-oxide, a mirtazapine metabolite, is produced by CYP1A2 and CYP3A4 in human liver.</p>Formula:C17H19N3OColore e forma:SolidPeso molecolare:281.359FFN246
CAS:<p>FFN246, a fluorescent probe, concurrently targets the serotonin transporter (SERT) and vesicular monoamine transporter 2 (VMAT2), exhibiting excitation and</p>Formula:C15H13FN2OPurezza:98%Colore e forma:SolidPeso molecolare:256.27ALEPH hydrochloride
CAS:<p>ALEPH (hydrochloride) acts as a partial agonist of h5-HT2A and h5-HT2B receptors, with EC50 values of 10.3 nM and 19.2 nM, respectively. It can induce head twitch responses in mice, with an ED50 of 0.80 mg/kg.</p>Formula:C12H20ClNO2SColore e forma:SolidPeso molecolare:277.81LY 344864 racemate
CAS:<p>LY 344864 racemate is a 5-HT1F receptor agonist.</p>Formula:C21H22FN3OPurezza:99.75%Colore e forma:SoildPeso molecolare:351.42Xylamidine
CAS:<p>Xylamidine is a biochemical.</p>Formula:C19H24N2O2Colore e forma:SolidPeso molecolare:312.41BMY-14802
CAS:<p>BMY-14802 (alpha-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazine butanol) is a selective and orally active sigma-1 antagonist with an IC50 of 112 nM.</p>Formula:C18H22F2N4OPurezza:99.84%Colore e forma:SoildPeso molecolare:348.39Donitriptan hydrochloride
CAS:<p>Donitriptan hydrochloride (Donitriptan monohydrochloride) is a potent, high efficacy agonist of 5-HT1B/1D receptors with pKis of 9.4 and 9.3, respectively</p>Formula:C23H26ClN5O2Purezza:99.8% - 99.86%Colore e forma:SolidPeso molecolare:439.94isomer-Cilansetron
CAS:<p>isomer-Cilansetron is an isomer of Cilansetron.</p>Formula:C20H21N3OPurezza:99.92% - 99.96%Colore e forma:SoildPeso molecolare:319.45-HT2C agonist-4
CAS:<p>Compound 3i, a 5-HT2C agonist-4, acts as an agonist for the 5-HT2C receptor with an EC50 of 5.7 nM. It is capable of reducing locomotor activity in zebrafish larvae.</p>Formula:C24H25N5OColore e forma:SolidPeso molecolare:399.49Imipramine N-oxide
CAS:<p>Imipramine N-oxide is a tricyclic antidepressant (TCA) and imipramine analogue used to treat depression.</p>Formula:C19H24N2OPurezza:99.80%Colore e forma:SolidPeso molecolare:296.41Alverine hydrochloride
CAS:<p>Alverine hydrochloride is a parasympatholytic.</p>Formula:C20H28ClNColore e forma:SolidPeso molecolare:317.95-methoxy-α-Ethyltryptamine
CAS:<p>5-Methoxy-alpha-ethyltryptamine is a psychoactive substance that can cause various effects. It belongs to the tryptamine chemical class and can be used for various psychoactive and stimulant effects. </p>Formula:C13H18N2OPurezza:98.25%Colore e forma:SolidPeso molecolare:218.29HDAC6-IN-49
<p>HDAC6-IN-49 (Compound 3) is an inhibitor of HDAC, with IC50 values of 0.012 and 0.735 µM against HDAC6 and HDAC1, respectively. Additionally, it inhibits MAO-B, cholinesterase (ChE), histamine receptor (H3R), and serotonin 6 receptor (5-HT6R). HDAC6-IN-49 exhibits neuroprotective effects in SH-SY5Y cells and enhances cognitive functions and motor abilities in fruit fly models of Parkinson's disease and C. elegans models of Alzheimer's disease.</p>Colore e forma:Odour Solid4-Chloromethamphetamine hydrochloride
CAS:<p>4-Chloromethamphetamine hydrochloride is a novel psychoactive substance belonging to the amphetamine class.</p>Formula:C10H15Cl2NColore e forma:SolidPeso molecolare:220.141,8-Cineole
CAS:<p>Eucalyptol, a natural monoterpenoid and cyclic ether found in eucalyptus species, effectively controls excessive airway mucus secretion and asthma by inhibiting pro-inflammatory cytokines. It serves as an efficacious treatment for non-purulent sinusitis, reducing inflammation and pain when applied topically, and demonstrating leukemic cell-killing capabilities in vitro.</p>Formula:C10H18OPurezza:97.44% - 97.44%Colore e forma:SolidPeso molecolare:154.25Mosapride citrate dihydrate
CAS:<p>Mosapride Citrate, a 5-HT4 agonist, boosts gut movement by enhancing acetylcholine release.</p>Formula:C27H35ClFN3O11Purezza:98%Colore e forma:SolidPeso molecolare:632.04Tiflucarbine
CAS:<p>Tiflucarbine is a potential non-selective 5-HT agonist with antidepressant activity.Tiflucarbine dose-dependently increased the specific activity of soluble</p>Formula:C16H17FN2SPurezza:>99.99%Colore e forma:SolidPeso molecolare:288.38LEK 8804
CAS:<p>LEK 8804 is a 5-HT(2) receptor antagonist and 5-HT(1A) receptor agonist.</p>Formula:C19H19N3OColore e forma:SolidPeso molecolare:305.37DOAM
CAS:<p>DOAM is an antagonist of the 5-HT2 receptor.</p>Formula:C16H27NO2Colore e forma:SolidPeso molecolare:265.39R 50595
CAS:<p>R 50595 is a selective non-competitive cisapride antagonist.</p>Formula:C30H35Cl2F2N3O3Purezza:98%Colore e forma:SolidPeso molecolare:594.52Desmethyl Mirtazapine (hydrochloride)
CAS:<p>Desmethyl mirtazapine is a metabolite of the antidepressant mirtazapine.1It is formed from mirtazapine by the cytochrome P450 (CYP) isoform CYP3A4.</p>Formula:C16H18ClN3Colore e forma:SolidPeso molecolare:287.79SB 216641
CAS:<p>SB 216641 is a 5-HT (1B/1D) antagonist with anxiolytic activity for the study of anxiety disorders and depression.</p>Formula:C28H30N4O4Purezza:98.09%Colore e forma:SolidPeso molecolare:486.56MR33317
<p>MR33317 is an inhibitor of acetylcholinesterase with an IC50 value of 41 nM. Additionally, it acts as an agonist for brain 5-HT4 receptors.</p>Formula:C22H28ClN3O2Peso molecolare:401.187PF-03382792
CAS:<p>PF-03382792 is a small molecule 5-HT4 receptor activator for the study of Alzheimer's disease.</p>Formula:C23H32FN3O4Purezza:99.64%Colore e forma:SolidPeso molecolare:433.524-Hydroxy MET
CAS:4-Hydroxy MET (4-HO-MET) is a tryptamine-based new psychoactive substance (NPS), structurally similar to the endogenous neurotransmitter serotonin. It has hallucinogenic properties that affect mood, movement, and cognitive functions.Formula:C13H18N2OColore e forma:SolidPeso molecolare:218.3HTR2A antagonist 1
<p>HTR2A antagonist 1 (Compound 15f) is an HTR2A antagonist with an IC50 of 42.79 nM. It induces sub-G1 cell cycle arrest and apoptosis in colorectal cancer cells by activating the p53/p21/caspase 3 signaling pathway. HTR2A antagonist 1 exhibits good liver microsomal stability and is useful for colorectal cancer research.</p>Formula:C35H43Cl2F2N5O4Colore e forma:SolidPeso molecolare:706.65
