Beta amiloide
Gli inibitori del beta-amiloide sono composti che mirano specificamente a inibire la formazione o l'aggregazione dei peptidi beta-amiloidi, coinvolti in modo critico nella patogenesi della malattia di Alzheimer. L'accumulo di placche di beta-amiloide nel cervello è uno dei tratti patologici distintivi della malattia, contribuendo alla disfunzione neuronale e al declino cognitivo. Inibendo l'aggregazione del beta-amiloide, questi inibitori sono studiati come potenziali agenti terapeutici per rallentare o prevenire la progressione della malattia di Alzheimer. Presso CymitQuimica, offriamo una gamma di inibitori del beta-amiloide di alta qualità per supportare la tua ricerca nella neurodegenerazione, nell'aggregazione proteica e nella terapia dell'Alzheimer.
Trovati 227 prodotti di "Beta amiloide"
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AC 253
CAS:Amylin (AMY3) receptor antagonist; blocks cAMP, Ca2+, PKA, MAPK, Akt, and cFOS activity; prevents Aβ-induced neuronal death. Cyclic AC 253 variant exists.Formula:C122H196N40O39Purezza:98%Colore e forma:SolidPeso molecolare:2847.11Cu(II)GTSM
CAS:Cu(II)GTSM is a cell permeable copper complex inhibits GSK3β activity and suppresses levels of neurotoxic amyloid β-trimers and phosphorylated tau.Formula:C6H10CuN6S2Purezza:99.21%Colore e forma:SolidPeso molecolare:293.86Ref: TM-T40792
1mg38,00€5mg80,00€10mg126,00€25mg277,00€50mg472,00€100mg790,00€200mg1.074,00€1mL*10mM (DMSO)87,00€AZD4694
CAS:Flutafuranol (AZD4694/NAV4694) binds beta-amyloid, potential PET tracer for Alzheimer's. Non-F18 version supplied.Formula:C14H11FN2O2Colore e forma:SolidPeso molecolare:258.25TH-237A
CAS:TH-237A is a novel neuroprotective agent exhibiting favorable permeation across the blood-brain barrier.Formula:C18H17F2NO3Purezza:98%Colore e forma:SolidPeso molecolare:333.335(Rac)-Z-Phe-Phe-FMK
CAS:(Rac)-Z-Phe-Phe-FMK (Cathepsin L-IN-2) is a cathepsin L inhibitor that inhibits the tendency of β-amyloid to induce apoptotic changes .Formula:C27H27FN2O4Purezza:98.27%Colore e forma:SolidPeso molecolare:462.51Begacestat
CAS:Begacestat (GSI-953) is a potent and selective gamma-secretase inhibitor that inhibits Amyloid-beta, inhibits cleavage of APP,,Alzheimer's disease.Formula:C9H8ClF6NO3S2Colore e forma:SolidPeso molecolare:391.74ARN2966
CAS:ARN2966 is an inhibitor of amyloid precursor protein (APP)and amyloid-β (Aβ) secretion.Formula:C12H12N2OPurezza:99.52% - 99.86%Colore e forma:SolidPeso molecolare:200.24Ref: TM-T7490
1mg37,00€5mg79,00€10mg119,00€25mg235,00€50mg378,00€100mg560,00€500mg1.216,00€1mL*10mM (DMSO)87,00€Anle138b
CAS:Anle138b: a novel oligomer modulator for disease-modifying therapy of neurodegenerative diseases such as prion and Parkinson's diseaseFormula:C16H11BrN2O2Purezza:98.88% - 99.82%Colore e forma:SolidPeso molecolare:343.17Frentizole
CAS:Frentizole, an immunosuppressive agent, is an inhibitor of the Aβ-ABAD interactionFormula:C15H13N3O2SPurezza:99.82%Colore e forma:SolidPeso molecolare:299.35TAE-1
CAS:<p>TAE-1 is an inhibitor of amyloid-β fibril formation and aggregation. It inhibits cholinesterases AChE and BuChE with IC50 of 0.3 μM and 3.9 μM, respectively.</p>Formula:C39H51I3N6O9Purezza:94.58%Colore e forma:SolidPeso molecolare:1128.57JLK6
CAS:JLK6 was a gamma-secretase inhibitor that does not interfere with Notch signallingFormula:C10H8ClNO3Purezza:96.50%Colore e forma:SolidPeso molecolare:225.63Ref: TM-T21890
1mg88,00€5mg160,00€10mg224,00€25mg374,00€50mg532,00€100mg723,00€200mg938,00€1mL*10mM (DMSO)169,00€PBD-150
CAS:PBD-150 is an inhibitor of human glutaminyl cyclase (hQC) Y115E-Y117E variant( ki : 490 nM)Formula:C15H20N4O2SPurezza:99.68%Colore e forma:SolidPeso molecolare:320.41CRANAD 2
CAS:CRANAD-2, a near-infrared probe, detects amyloid-beta in vivo, increasing fluorescence 70x and shifting blue 90 nm upon binding.Formula:C23H25BF2N2O2Purezza:99.44%Colore e forma:Dark Blue To Black PowderPeso molecolare:410.271,1'-Methylenedi-2-naphthol
CAS:1,1'-Methylenedi-2-naphthol target CYP2C19 - cytochrome P450 family 2 subfamily C member 19 (human).Formula:C21H16O2Purezza:98.91%Colore e forma:Light Pink To Light Brown Crystalline PowderPeso molecolare:300.35Azeliragon HCl
CAS:Azeliragon: potent oral RAGE inhibitor, blocks Alzheimer's-linked amyloid brain entry.Formula:C32H40Cl3N3O2Colore e forma:SolidPeso molecolare:605.04Semagacestat
CAS:Semagacestat (LY450139) (LY450139) is a γ-secretase blocker for Aβ42/Aβ40/Aβ38 (IC50: 10.9/12.1/12.0 nM) and also inhibits Notch signaling (IC50: 14.1 nM).Formula:C19H27N3O4Purezza:97.1% - 99.9%Colore e forma:SolidPeso molecolare:361.44FPS-ZM1
CAS:FPS-ZM1 is a high-affinity RAGE specific inhibitor that blocks Aβ binding to the V domain of RAGE.Formula:C20H22ClNOPurezza:99.32% - 99.52%Colore e forma:SolidPeso molecolare:327.85Ref: TM-T3259
5mg50,00€10mg57,00€25mg92,00€50mg147,00€100mg220,00€200mg350,00€500mg590,00€1mL*10mM (DMSO)52,00€Dihydroergocristine mesylate
CAS:DHEC mesylate is a vasodilator and α-adrenergic antagonist used for vascular dementia and as a geroprotector.Formula:C36H45N5O8SPurezza:98.9% - 99.79%Colore e forma:SolidPeso molecolare:707.84Miridesap
CAS:Miridesap (GSK2315698) rapidly depletes SAP in blood, cerebrospinal fluid, and amyloid deposits via liver clearance.Formula:C16H24N2O6Purezza:≥95%Colore e forma:SolidPeso molecolare:340.37Pyridoxal 5'-phosphate hydrate
CAS:Pyridoxal 5'-phosphate hydrate (PLP)(1:x), the active form of vitamin B6, is a cofactor for many different enzymes involved in transamination reactions,Formula:C8H10NO6PPurezza:97.52%Colore e forma:SolidPeso molecolare:247.14
