Beta amiloide
Gli inibitori del beta-amiloide sono composti che mirano specificamente a inibire la formazione o l'aggregazione dei peptidi beta-amiloidi, coinvolti in modo critico nella patogenesi della malattia di Alzheimer. L'accumulo di placche di beta-amiloide nel cervello è uno dei tratti patologici distintivi della malattia, contribuendo alla disfunzione neuronale e al declino cognitivo. Inibendo l'aggregazione del beta-amiloide, questi inibitori sono studiati come potenziali agenti terapeutici per rallentare o prevenire la progressione della malattia di Alzheimer. Presso CymitQuimica, offriamo una gamma di inibitori del beta-amiloide di alta qualità per supportare la tua ricerca nella neurodegenerazione, nell'aggregazione proteica e nella terapia dell'Alzheimer.
Trovati 227 prodotti di "Beta amiloide"
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TC-E 5006
CAS:γ-secretase modulatorFormula:C29H29F4NO2Purezza:98%Colore e forma:SolidPeso molecolare:499.54OAB-14
CAS:OAB-14, a Bexarotene derivative, enhances β-amyloid clearance and cognitive function in APP/PS1 mice, improving Alzheimer's symptoms.Formula:C32H46N4O2Colore e forma:SolidPeso molecolare:518.73q-FTAA
CAS:q-FTAA targets Aβ1-42 fibrils (330-630 nM) and ADPBC (300-500 nM), useful in Alzheimer's disease research.Formula:C21H14O6S4Colore e forma:SolidPeso molecolare:490.59YIAD-0205
CAS:YIAD-0205, an orally administered inhibitor of Aβ(1-42) aggregation, has exhibited in vivo efficacy in a 5XFAD transgenic mouse model that harbors five familialFormula:C26H16Br2ClN3Colore e forma:SolidPeso molecolare:565.69LC kinetic stabilizer-2
CAS:LC Kinetic Stabilizer-2 is a powerful stabilizer for amyloidogenic immunoglobulin light chains (LC), demonstrating significant efficacy with an EC50 of 24 nM.Formula:C28H31N3O3Colore e forma:SolidPeso molecolare:457.56K 01-162
CAS:K 01-162 binds and destabilizes AβO (β-amyloid), with an EC50 of 80 nM.Formula:C15H14BrNColore e forma:SolidPeso molecolare:288.18Chrysamine G
CAS:Chrysamine G, Congo red analog, blocks Aβ toxicity, probes Alzheimer's amyloid.Formula:C26H16N4Na2O6Colore e forma:SolidPeso molecolare:526.416Glutaminyl Cyclase Inhibitor 2
CAS:Glutaminyl Cyclase Inhibitor 2 is a glutaminyl cyclase inhibitor (IC50: 1.23 μM).Formula:C19H20FN3Purezza:98%Colore e forma:SolidPeso molecolare:309.38BTA-1
CAS:BTA-1 is an uncharged derivative of thioflavin-T that has high affinity for Aβ fibrils and shows very good brain entry and clearance [1].Formula:C14H12N2SColore e forma:SolidPeso molecolare:240.32CGP52411
CAS:CGP52411 is an orally active, and ATP-competitive inhibitor of EGFR (IC50: 0.3 μM).Formula:C20H15N3O2Purezza:99.78%Colore e forma:SolidPeso molecolare:329.35JNJ-40418677
CAS:JNJ-40418677 is a γ-secretase modulator that selectively blocks γ-site cleavage of the APP without affecting the processing of Notch.Formula:C26H22F6O2Purezza:98%Colore e forma:SolidPeso molecolare:480.44BuChE-IN-2
CAS:BuChE-IN-2 inhibits BuChE (IC50: 1.28 μM), NO (0.67 μM), Aβ, ROS, chelates Cu2+, penetrates BBB, used in Alzheimer's research.Formula:C28H20F4N6O3Colore e forma:SolidPeso molecolare:564.49TML-6
CAS:TML-6, an oral derivative of curcumin, may help in Alzheimer's research by targeting amyloid production and various molecular pathways.Formula:C30H37NO7Purezza:99.71%Colore e forma:SolidPeso molecolare:523.62Ref: TM-T37148
1mg94,00€5mg222,00€10mg356,00€25mg708,00€50mg1.063,00€100mg1.674,00€1mL*10mM (DMSO)256,00€SV5
CAS:SV5: potent anti-Alzheimer's, protects SHSY-5Y from Aβ1-42 death, stable with optimal pharmacology in plasma, antioxidant, neuroprotective.Formula:C21H30N2O4S2Colore e forma:SolidPeso molecolare:438.6Antioxidant agent-2
CAS:Antioxidant agent-2 (3c), BBB-permeable, selectively chelates metals; shows neuroprotection, fights liver damage in Alzheimer's research.Formula:C23H26N2O7Colore e forma:SolidPeso molecolare:442.46BACE1/2-IN-1
CAS:BACE1/2-IN-1 inhibits BACE1/2 with IC50s of 0.01μM/0.0053μM, has better permeability and lower Pgp efflux but reduced metabolic stability.Formula:C21H31N5OSColore e forma:SolidPeso molecolare:401.57SEN-1269
CAS:SEN-1269 prevents amyloid-β aggregation, shields neurons, and improves memory by hindering Aβ(1-42)-induced issues.Formula:C18H18N4O2Purezza:98%Colore e forma:SolidPeso molecolare:322.36AY1511
CAS:AY1511 is a low cytotoxic inhibitor of amyloid β (Aβ) aggregation [1].Formula:C17H14O6Colore e forma:SolidPeso molecolare:314.29Glutaminyl Cyclase Inhibitor 5
Glutaminyl Cyclase Inhibitor 5 is a potent, selective inhibitor of human glutaminyl cyclase (hQC), demonstrating an inhibition concentration half-max (IC 50) ofFormula:C22H30N6OColore e forma:SolidPeso molecolare:394.51Fenlean
CAS:"Fenlean (FLZ) in phase I trial at Chinese Academy's Institute of Pharmacy for Parkinson's treatment."Formula:C26H27NO6Purezza:98.99%Colore e forma:SolidPeso molecolare:449.5Ref: TM-T31773
1mg78,00€2mg103,00€5mg168,00€10mg311,00€25mg562,00€50mg843,00€100mg1.008,00€200mg1.359,00€
