Beta amiloide
Gli inibitori del beta-amiloide sono composti che mirano specificamente a inibire la formazione o l'aggregazione dei peptidi beta-amiloidi, coinvolti in modo critico nella patogenesi della malattia di Alzheimer. L'accumulo di placche di beta-amiloide nel cervello è uno dei tratti patologici distintivi della malattia, contribuendo alla disfunzione neuronale e al declino cognitivo. Inibendo l'aggregazione del beta-amiloide, questi inibitori sono studiati come potenziali agenti terapeutici per rallentare o prevenire la progressione della malattia di Alzheimer. Presso CymitQuimica, offriamo una gamma di inibitori del beta-amiloide di alta qualità per supportare la tua ricerca nella neurodegenerazione, nell'aggregazione proteica e nella terapia dell'Alzheimer.
Trovati 222 prodotti di "Beta amiloide"
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SCH-900229
CAS:SCH-900229, a potent presenilin 1 selective γ-secretase inhibitor, used to treat Alzheimer’s Disease.Formula:C21H21ClF2O6S2Colore e forma:SolidPeso molecolare:506.97mcK6A1
<p>mcK6A1 serves as an inhibitor of amyloid-β (Aβ) aggregation, selectively binding to the 16KLVFFA21 fragment of Aβ42, leading to the formation of an extended β-sheet structure and preventing the formation of Aβ42 oligomers. This compound is valuable for research into Alzheimer's disease and other amyloid-related disorders.</p>Formula:C71H99N17O16Colore e forma:SolidPeso molecolare:1446.65β-Amyloid (22-35)
CAS:β-Amyloid (22-35) is a 14-aa peptide, shows aggregates and induces neurotoxicity in the hippocampal cells.Formula:C59H102N16O21SPurezza:98%Colore e forma:SolidPeso molecolare:1403.62BSBM6
CAS:BSBM6 is an inhibitor of Aβ aggregation and neuronal toxicity that acts by reversing the aggregation and toxicity of amyloid-β peptides.Formula:C23H29N3O5Purezza:98%Colore e forma:SolidPeso molecolare:427.49(Glu20)-Amyloid β-Protein (1-42)
CAS:<p>(Glu20)-Amyloid β-Protein (1-42) represents a variant of amyloid β-protein (Aβ) that fibrillizes more slowly.</p>Formula:C199H309N55O62SColore e forma:SolidPeso molecolare:4495.98FITC-β-Ala-Amyloid β-Protein (1-42) (ammonium)
FITC-β-Ala-Amyloid β-Protein (1-42) (ammonium) is a FITC-labeled amyloid beta monomer, Alzheimer’s research, drug screening, and biomolecular studies.Formula:C227H330N58O66S2Colore e forma:SolidPeso molecolare:4991.53β-Amyloid (1-43)(human) TFA
β-Amyloid (1-43)(human) TFA exhibits greater aggregation tendencies and heightened toxicity compared to its well-established counterpart, Aβ1-42.Formula:C209H319F3N56O64SColore e forma:SolidPeso molecolare:4729.21(Met(O)35)-Amyloid β-Protein (1-42)
(Met(O)35)-Amyloid β-Protein (1-42) represents the oxidized form of Methionine 35 in Aβ42, capable of producing an oligomer size distribution akin to that ofFormula:C203H311N55O61SColore e forma:SolidPeso molecolare:4530.04RI-OR2-TAT
CAS:RI-OR2-TAT is a brain-penetrable inhibitor targeting β-amyloid (β-Amyloid) oligomerization. It is engineered by integrating the HIV protein transduction domain TAT into RI-OR2. RI-OR2-TAT binds to Aβ42 fibrils with a Kd value of 58-125 nM. It reduces Aβ aggregation and plaque levels, diminishes microglial activation and oxidative damage, and enhances the number of young neurons in the dentate gyrus.Formula:C117H201N49O23Colore e forma:SolidPeso molecolare:2662.16β-Amyloid (11-22)
CAS:β-Amyloid (11-22) is a peptide fragment of β-Amyloid.Beta-amyloid peptide (Abeta), the major constituent of amyloid plaques in the brains of Alzheimer’sFormula:C70H102N18O18Purezza:98%Colore e forma:SolidPeso molecolare:1483.677-Deoxy-trans-dihydronarciclasine
CAS:7-Deoxy-trans-dihydronarciclasine is an alkaloid that functions as a tobacco mosaic virus (TMV) inhibitor with an IC50 of 1.80 μM and also serves as an anti-Formula:C14H15NO6Colore e forma:SolidPeso molecolare:293.27β-Amyloid (13-27)
CAS:β-Amyloid (13-27) is a peptide consisting of amino acid of 13 to 27 of beta amyloid protein.Formula:C84H126N24O24Purezza:98%Colore e forma:SolidPeso molecolare:1856.05β-Amyloid (18-28)
CAS:Intracerebroventricular administration of synthetic peptides Beta-amyloid (12-20), (12-28), and (18-28) causes amnesia in mice.Formula:C55H81N13O18Purezza:98%Colore e forma:SolidPeso molecolare:1212.31β-Amyloid (33-40)
CAS:β-Amyloid (33-40) is a peptide comprising amino acids 33 to 40 of the beta-amyloid protein.Formula:C32H58N8O9SPurezza:98%Colore e forma:SolidPeso molecolare:730.92(Gln22)-Amyloid β-Protein (1-42)
CAS:(Gln22)-Amyloid β-Protein (1-42), a Dutch mutation (E22Q) variant of β-Amyloid (1-42), demonstrates increased fibrillogenic and pathogenic characteristics [1].Formula:C203H312N56O59SColore e forma:SolidPeso molecolare:4513.05β-Amyloid (1-16)
CAS:β-Amyloid (1-16) is an amyloidogenic protein fragment with a sequence derived from β-amyloid.Formula:C84H119N27O28Purezza:98%Colore e forma:SolidPeso molecolare:1955.041H-Indole-3-carboxylic acid, 5-[2-hydroxy-3-[[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]amino]propoxy]-2-methyl-1-(4-methylphenyl)-, ethyl ester
CAS:<p>Compound 5936-0108对β-淀粉样蛋白可能具有调节作用。</p>Formula:C26H34N2O7Purezza:99.44%Colore e forma:SoildPeso molecolare:486.56AC 253
CAS:Amylin (AMY3) receptor antagonist; blocks cAMP, Ca2+, PKA, MAPK, Akt, and cFOS activity; prevents Aβ-induced neuronal death. Cyclic AC 253 variant exists.Formula:C122H196N40O39Purezza:98%Colore e forma:SolidPeso molecolare:2847.11Chemerin-9 (149-157) TFA
Chemerin-9 (149-157) TFA is a peptide located at positions 149-157 of chemerin-9, acting as a ChemR23/CMKLR1 agonist.Formula:C56H67F3N10O15Purezza:99.77%Colore e forma:SolidPeso molecolare:1177.18CHF-5022
CAS:CHF-5022 is a nonsteroidal anti-inflammatory drug that selectively inhibits the production of beta-amyloid protein (1-42) (ABETA42).Formula:C17H12F4O2Colore e forma:SolidPeso molecolare:324.27β-Amyloid Protein Precursor 770 (135-155)
CAS:<p>Beta-Amyloid Protein Precursor 770 (135-155)Aβ Protein Precursor 770 (135-155)</p>Formula:C116H172N35O31S2Purezza:98%Colore e forma:SolidPeso molecolare:2617.962,3-Dehydrosilybin A
CAS:2,3-Dehydrosilybin A is a useful organic compound for research related to life sciences and the catalog number is T125202.Formula:C25H20O10Colore e forma:SolidPeso molecolare:480.43GSK-3β inhibitor 27
GSK-3β inhibitor27 (Compound 1c) is a reversible, competitive inhibitor of GSK-3β with an IC50 value of 2.2 μM. It inhibits tau hyperphosphorylation and reduces Aβ protein aggregation, demonstrating metal chelation and neuroprotective potential. GSK-3β inhibitor27 is promising for research into neurodegenerative diseases, such as Alzheimer's disease.Formula:C16H17ClN4O2Colore e forma:SolidPeso molecolare:332.79Anti-Amyloid β Antibody (scFv59)
Anti-Amyloid Beta Antibody (scFv59) is a human-derived antibody produced in CHO cells that targets Amyloid-β. For isotype control, please refer to Human IgG1 kappa, Isotype Control.Colore e forma:Odour Liquid5-FAM-β-Amyloid (1-28)
5-FAM-β-Amyloid (1-28) is a fluorescently-labeled peptide corresponding to the first 28 amino acids of the β-Amyloid protein.Formula:C166H219N41O52Colore e forma:SolidPeso molecolare:3620.76β-Amyloid (1-17)
CAS:This synthetic peptide consists of amino acids 1 to 17 of beta amyloid protein. This peptide can be employed in beta amyloid solubility studies.Formula:C90H130N28O29Purezza:98%Colore e forma:SolidPeso molecolare:2068.2Methoxy-X04
CAS:<p>Methoxy-X04, a derivative of Congo red and Chrysamine-G, is a brain-permeable fluorescent probe for amyloid-β (Aβ).</p>Formula:C23H20O3Purezza:98.96%Colore e forma:SolidPeso molecolare:344.4Aβ-IN-7
Aβ-IN-7 (compound 5a) acts as a potent inhibitor of Aβ aggregation, stabilizing Aβ monomers at 50 μM concentration to prevent them from forming larger oligomersFormula:C14H10N2SColore e forma:SolidPeso molecolare:238.31Biotin-β-Amyloid (1-42), human TFA
Biotin-β-Amyloid (1-42), human TFA, also known as Biotin-Amyloid β-Peptide (1-42) (human) TFA, is a biotin-labeled 42-amino acid peptide implicated in theFormula:C215H326F3N57O64S2Colore e forma:SolidPeso molecolare:4854.36Pep63
CAS:Pep63, a neuroprotective peptide (VFQVRARTVA), enhances synaptic plasticity and memory. It competitively binds with Aβ1-42 oligomers, thereby inhibiting the formation of Aβ fibrils. Pep63 is employed in research focused on Alzheimer's disease (AD).Formula:C51H87N17O13Peso molecolare:1146.34RAGE antagonist peptide
CAS:RAGE antagonist blocks S100P/A4, HMGB-1; hinders glioma growth, metastasis; reduces PDAC cell growth, NF-κB activity; counters TDI effects in mice.Formula:C57H101N13O17SPurezza:98%Colore e forma:SolidPeso molecolare:1272.56β-Amyloid (1-11)
CAS:Anionic interaction of Beta-amyloid (1-11) with Factor XII is suspected to cause massive activation of the C4 (complement 4) system in the cerebrospinal fluidFormula:C56H76N16O22Purezza:98%Colore e forma:SolidPeso molecolare:1325.3Merinetug
CAS:Merinetug is a humanized IgG1κ antibody that targets Amyloid Beta (Aβ). Its corresponding isotype control is Human IgG1 kappa, Isotype Control.Colore e forma:LiquidSabirnetug
CAS:Sabirnetug is a humanized IgG2κ monoclonal antibody that specifically targets the amyloid-β (A4) precursor protein.Colore e forma:LiquidSQ-3
SQ-3, a quinoline analogue, prefers α-syn (Ki=39.3nM) to Aβ (Ki=230nM), and [18F]SQ3 is a lead for α-syn probes. [1]Formula:C21H21FN2OColore e forma:SolidPeso molecolare:336.4Davunetide
CAS:<p>Davunetide: neuroprotective 8-amino acid peptide, improves daily function in schizophrenia, boosts memory in mild cognitive impairment.</p>Formula:C36H60N10O12Purezza:98%Colore e forma:SolidPeso molecolare:824.92BIBD-124
CAS:BIBD-124, with an IC50 value of 9.51 nM, effectively binds to amyloid beta (Aβ) plaques.Formula:C19H24FN3O3Colore e forma:SolidPeso molecolare:361.41β-Amyloid (1-40)
CAS:Amyloid β1-40 is one of the fragments generated after cleavage of the amyloid peptide precursor protein by β and γ secretases.Formula:C194H295N53O58SPurezza:98%Colore e forma:SolidPeso molecolare:4329.82β-Amyloid (1-34)
CAS:This is a fragment of beta-amyloid peptide. It has amino acids 1 through 34.Formula:C170H253N47O52Purezza:98%Colore e forma:SolidPeso molecolare:3787.2γ-Secretase Modulators
CAS:gamma-Secretase Modulators serves as a useful treatment for Alzheimer's disease by inhibiting the production of Amyloid-β.Formula:C26H24F3N3O3Purezza:98%Colore e forma:SolidPeso molecolare:483.48p-HTAA
CAS:Pentamer Hydrogen Thiophene Acetic Acid (p-HTAA) is a compound that specifically targets and labels amyloid-beta (Aβ) deposits in the brains of living mice [1].Formula:C24H16O4S5Colore e forma:SolidPeso molecolare:528.71β-Amyloid (1-20)
CAS:<p>This synthetic peptide consists of amino acids 1 to 20 of beta amyloid protein.</p>Formula:C113H157N31O32Purezza:98%Colore e forma:SolidPeso molecolare:2461.7β-Amyloid (12-20)
CAS:β-Amyloid (12-20) is a peptide fragment of β-Amyloid.Thsis peptide contain the amino acid residues VFF at position (18-20), suggesting that this triad hasFormula:C57H83N15O11Purezza:98%Colore e forma:SolidPeso molecolare:1154.36β-Amyloid (35-42)
CAS:β-Amyloid (35-42) is a peptide derived from the beta-amyloid protein, encompassing amino acids 35 through 42.Formula:C33H60N8O9SPurezza:98%Colore e forma:SolidPeso molecolare:744.94SLAFVDVLN
SLAFVDVLN is a peptide molecule that functions as a BACE-1 inhibitor, exhibiting a Ki value of 94 nM. Additionally, SLAFVDVLN is capable of reducing the production of Aβ42.Formula:C45H72N10O14Colore e forma:SolidPeso molecolare:977.11Aβ-IN-8
Aβ-IN-8, also known as compound 7e, is a potent inhibitor of Aβ aggregation [1].Formula:C22H16F3N3O3SColore e forma:SolidPeso molecolare:459.44β-Amyloid (1-38), mouse, rat
CAS:β-Amyloid (1-38), derived from mice and rats, is a chemical compound comprising 38 amino acids, specifically residues 1-38 of the Aβ peptide.Colore e forma:Solidβ-Amyloid (1-9)
CAS:This is an N-terminal fragment of beta amyloid.Formula:C42H60N14O17Purezza:98%Colore e forma:SolidPeso molecolare:1033.01LPYFD-NH2
CAS:neuroprotective peptide that binds to amyloid beta (Aβ)Formula:C33H44N6O8Purezza:98%Colore e forma:SolidPeso molecolare:652.74(Rac)-Z-Phe-Phe-FMK
CAS:(Rac)-Z-Phe-Phe-FMK (Cathepsin L-IN-2) is a cathepsin L inhibitor that inhibits the tendency of β-amyloid to induce apoptotic changes .Formula:C27H27FN2O4Purezza:98.27%Colore e forma:SolidPeso molecolare:462.51
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