COX
Gli inibitori della cicloossigenasi (COX) sono composti che bloccano l'attività degli enzimi COX, coinvolti nella produzione di prostaglandine, mediatori chiave dell'infiammazione e del dolore. In neuroscienze, gli inibitori della COX sono studiati per il loro potenziale nel ridurre la neuroinfiammazione, implicata in varie malattie neurodegenerative come l'Alzheimer, il Parkinson e la sclerosi multipla. Inibendo la COX, questi composti possono aiutare a mitigare i processi infiammatori nel cervello e a proteggere dai danni neuronali. Presso CymitQuimica, offriamo una gamma di inibitori della COX per supportare la tua ricerca sulla neuroinfiammazione, la gestione del dolore e le malattie neurodegenerative.
Trovati 562 prodotti di "COX"
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Deracoxib
CAS:<p>Deracoxib (SC 46) is a selective COX-2 inhibitor, non-steroidal, non-narcotic anti-inflammatory drug with an IC50 of 70-150 μM for osteosarcoma cells.</p>Formula:C17H14F3N3O3SPurezza:98.94% - 99.81%Colore e forma:SolidPeso molecolare:397.37Guaiacol
CAS:<p>Guaiacol, a flavorant precursor, has medicinal uses and serves as an oxygen indicator turning yellow-brown at 470 nm.</p>Formula:C7H8O2Purezza:99.95%Colore e forma:Colourless To Pale Yellow Solid CrystallinePeso molecolare:124.14Ketorolac tromethamine salt
CAS:Formula:C19H24N2O6Purezza:98%Colore e forma:SolidPeso molecolare:376.4037Metamizole sodium hydrate
CAS:<p>Metamizole sodium hydrate (Analgin) is a potent analgesic drug that has been demonstrated to inhibit cyclooxygenase (COX).</p>Formula:C13H18N3NaO5SPurezza:99.69% - 99.89%Colore e forma:White Or Light Yellow Crystalline Powder Odorless Tiny BitterPeso molecolare:351.36(R)-Naproxen
CAS:<p>(R)-Naproxen: anti-inflammatory with antipyretic and analgesic effects; treats gout, dysmenorrhea, rheumatoid arthritis.</p>Formula:C14H14O3Purezza:99.62% - 99.94%Colore e forma:SolidPeso molecolare:230.262,3'-Bipyridine, 5-chloro-6'-methyl-3-[4-(methylsulfonyl)phenyl]-
CAS:Formula:C18H15ClN2O2SPurezza:99%Colore e forma:SolidPeso molecolare:358.8419Ref: IN-DA002878
1g28,00€5g69,00€10g128,00€15gPrezzo su richiesta1kgPrezzo su richiesta25g155,00€50gPrezzo su richiesta75gPrezzo su richiesta100g528,00€500gPrezzo su richiestaCatechin
CAS:<p>Catechin (Cianidanol) is a flavan-3-ol, a type of natural phenol and antioxidant.</p>Formula:C15H14O6Purezza:97.34% - 99.82%Colore e forma:SolidPeso molecolare:290.27Tebufelone
CAS:<p>Tebufelone is a potent NSAID, inhibits CO, has anti-inflammatory and analgesic properties, and blocks lipoxygenase products (IC50 ~20-22 microM).</p>Formula:C20H28O2Purezza:99.32%Colore e forma:SolidPeso molecolare:300.442-O-Sinapoyl makisterone A
<p>Compound 2, formally known as 2-O-Sinapoyl makisterone A, is a sinapinic acid-ecdysterone hybrid that acts as a selective inhibitor of COX-2, effectively</p>Formula:C39H56O11Purezza:98%Colore e forma:SolidPeso molecolare:700.8615-LOX-IN-2
<p>15-LOX-IN-2 (Compound 2a) is an orally active inhibitor of COX-2/15-LOX and a partial agonist of PPARγ. It exhibits anti-inflammatory activity by inhibiting levels of 20-HETE, IL-1β, and TNF-α in LPS-treated RAW 264.7 cells. Additionally, it significantly enhances glucose uptake without the presence of insulin and is applicable in metabolic disease research.</p>Colore e forma:Odour SolidCOX-1/2-IN-5
<p>COX-1/2-IN-5 (compound 2a) functions as a dual inhibitor of COX1/2, demonstrating inhibitory concentrations (IC50) of 2.650 μM and 0.958 μM, respectively, and</p>Formula:C21H22N2O5SPurezza:98%Colore e forma:SolidPeso molecolare:414.474-ACETAMIDOANTIPYRINE
CAS:<p>4-ACETAMIDOANTIPYRINE, with CAS No. 83-15-8, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 4-ACETAMIDOANTIPYRINE provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.</p>Formula:C13H15N3O2Colore e forma:SolidPeso molecolare:245.28COX-2-IN-33
<p>COX-2-IN-33 (compound 5f) is a selective COX-2 inhibitor with an IC50 value of 45.5 nM and exhibits potential as an anti-inflammatory agent.</p>Formula:C20H13ClF3N5O4Purezza:98%Colore e forma:SolidPeso molecolare:479.8Pemedolac
CAS:<p>Pemedolac (Dexpemedolac) is a small molecule COX inhibitor used to treat neurological disorders, skin and musculoskeletal disorders.</p>Formula:C22H23NO3Purezza:>99.99%Colore e forma:SolidPeso molecolare:349.42NF157
CAS:<p>NF157, a selective P2Y11 antagonist with pKi 7.35, lowers MMP-3/MMP-13, aiding OA treatment; IC50s: P2Y11 463 nM, P2Y1 1811 μM, P2Y2 170 μM.</p>Formula:C49H28F2N6Na6O23S6Purezza:98%Colore e forma:SolidPeso molecolare:1437.1COX-1/2-IN-4
<p>COX-1/2-IN-4 (compound 2b) is a dual COX-1 and COX-2 inhibitor with respective IC50 values of 0.239 μM for COX-1 and 0.191 μM for COX-2.</p>Formula:C22H24N2O2SPurezza:98%Colore e forma:SolidPeso molecolare:380.5Ketoprofen lysine salt
CAS:<p>Ketoprofen lysine salt is a lysine salt of ketoprofen, a Non-Steroidal Anti-Inflammatory Drug</p>Formula:C22H28N2O5Colore e forma:SolidPeso molecolare:400.48SARS-CoV-2 Mpro-IN-41
<p>SARS-CoV-2 Mpro-IN-41 (Compound 7e) is an orally active inhibitor targeting COX-2 and SARS-CoV-2 Mpro, with respective IC50 values of 9.66 μM and 13.24 μM. It also demonstrates inhibitory activity against COX-1 (IC50: 46.11 μM). This compound significantly suppresses the expression of inflammation-related cytokines such as TNF-α, IL-6, and IL-1β, exhibiting anti-inflammatory properties. By selectively inhibiting COX-2 and SARS-CoV-2 Mpro, SARS-CoV-2 Mpro-IN-41 exerts both anti-inflammatory and antiviral effects, making it a potential candidate for research in inflammation and COVID-19 treatment.</p>Formula:C27H23ClN4O3SColore e forma:SolidPeso molecolare:518.11794Anti-inflammatory agent 53
<p>Anti-inflammatory agent 52 (compound 7c) is an orally active, selective COX-2 inhibitor with demonstrated anti-HT29 metastatic activity, causing periodic arrest</p>Formula:C24H22N2O4SPurezza:98%Colore e forma:SolidPeso molecolare:434.51
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