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COX

COX

Gli inibitori della cicloossigenasi (COX) sono composti che bloccano l'attività degli enzimi COX, coinvolti nella produzione di prostaglandine, mediatori chiave dell'infiammazione e del dolore. In neuroscienze, gli inibitori della COX sono studiati per il loro potenziale nel ridurre la neuroinfiammazione, implicata in varie malattie neurodegenerative come l'Alzheimer, il Parkinson e la sclerosi multipla. Inibendo la COX, questi composti possono aiutare a mitigare i processi infiammatori nel cervello e a proteggere dai danni neuronali. Presso CymitQuimica, offriamo una gamma di inibitori della COX per supportare la tua ricerca sulla neuroinfiammazione, la gestione del dolore e le malattie neurodegenerative.

Trovati 562 prodotti di "COX"

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  • CAFESTOL

    CAS:
    <p>Cafestol, an ERK inhibitor, suppresses PGE2 and COX-2 by blocking NF-kB in LPS-stimulated RAW264.7 cells.</p>
    Formula:C20H28O3
    Purezza:97.06% - 99.08%
    Colore e forma:Solid
    Peso molecolare:316.43
  • RHC 80267

    CAS:
    <p>RHC 80267 (U-57908) is a selective inhibitor of DAGL (IC50 : 4 μM in canine platelets)</p>
    Formula:C20H34N4O4
    Purezza:99.54%
    Colore e forma:White Solid
    Peso molecolare:394.51
  • Revaprazan hydrochloride

    CAS:
    <p>Revaprazan hydrochloride (YH1885) is the hydrochloride salt form of a lipophilic, weak base with potassium-competitive acid blocking (P-CAB) activity.</p>
    Formula:C22H24ClFN4
    Purezza:99.62% - 99.91%
    Colore e forma:Solid
    Peso molecolare:398.9
  • Byakangelicol

    CAS:
    <p>Byakangelicol may reduce P-gp at BBB and has anti-inflammatory effects by hindering COX-2 and PGE2 in A549 cells.</p>
    Formula:C17H16O6
    Purezza:98.78% - 99.55%
    Colore e forma:Solid
    Peso molecolare:316.31
  • Pectolinarigenin

    CAS:
    <p>Pectolinarigenin has hepatoprotective and anti-inflammatory properties, acting through SOD and inhibiting eicosanoids.</p>
    Formula:C17H14O6
    Purezza:98.67% - 99.88%
    Colore e forma:Solid
    Peso molecolare:314.29
  • Compound Lup-20(29)-en-3-yl acetate


    <p>Lupeol acetate, a derivative of Lupeol, inhibits the progression of rheumatoid arthritis by downregulating TNF-α, IL-1β, MCP-1, COX-2, VEGF and granzyme B.</p>
    Formula:C32H52O2
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:468.75
  • N-tert-butyl-α-Phenylnitrone

    CAS:
    <p>N-tert-butyl-α-Phenylnitrone ((Z)-N-benzylidene-2-Methylpropan-2-aMine oxide) inhibits COX2 catalytic activity.</p>
    Formula:C11H15NO
    Purezza:99.46% - 99.84%
    Colore e forma:Solid
    Peso molecolare:177.24
  • CAY10404

    CAS:
    <p>CAY10404: potent COX-1/2 inhibitor; blocks PKB/Akt, MAPK pathways; triggers NSC-LC apoptosis; analgesic, anti-inflammatory, anti-cancer.</p>
    Formula:C17H12F3NO3S
    Purezza:99.02%
    Colore e forma:Solid
    Peso molecolare:367.34
  • Isofraxidin

    CAS:
    <p>Isofraxidin combats leukemia, ALI, and inflammation by modulating ROS, COX-2, PGE2, TNF-α, and p38/ERK1/2 pathways.</p>
    Formula:C11H10O5
    Purezza:99.51% - ≥95%
    Colore e forma:Solid
    Peso molecolare:222.19
  • Mofezolac

    CAS:
    <p>Mofezolac (formerly known as Disopain or N-22) is a highly selective COX-1 (cyclooxygenase-1) inhibitor with COXs selectivity index &gt; 6000</p>
    Formula:C19H17NO5
    Purezza:99.29%
    Colore e forma:Solid
    Peso molecolare:339.34
  • Firocoxib

    CAS:
    <p>Firocoxib (ML 1785713) is a selective non-steroidal inhibitor of cycooxygenase-2 (COX-2) (IC50 of 0.13 μM), with anti-inflammatory for use in dogs and horses.</p>
    Formula:C17H20O5S
    Purezza:99.84%
    Colore e forma:Solid
    Peso molecolare:336.4
  • Parecoxib

    CAS:
    <p>Parecoxib (SC 69124) is an effective and selective COX-2 inhibitor.</p>
    Formula:C19H18N2O4S
    Purezza:99.71% - 99.78%
    Colore e forma:Solid
    Peso molecolare:370.42
  • Prim-O-glucosylcimifugin

    CAS:
    <p>Prim-O-glucosylcimifugin (Cimifugin 7-glucoside) can inhibit the proliferation of SMC stimulated by TNF-alpha, increase the proportion of G0/G1 phase.</p>
    Formula:C22H28O11
    Purezza:98.57% - 99.92%
    Colore e forma:Solid
    Peso molecolare:468.45
  • Tazofelone

    CAS:
    <p>Tazofelone (LY-213829) is a NSAID used for the treatment of inflammatory bowel disease.</p>
    Formula:C18H27NO2S
    Purezza:99.89%
    Colore e forma:Solid
    Peso molecolare:321.48
  • (E)-Ethyl p-methoxycinnamate

    CAS:
    <p>1. (E)-Ethyl p-methoxycinnamate (EPMC) is an anticarcinogenic agent. 2. (E)-Ethyl p-methoxycinnamate (EPMC) is a glutathion S tranferase inhibitor.</p>
    Formula:C12H14O3
    Purezza:97.43%
    Colore e forma:Solid
    Peso molecolare:206.24
  • SC-560

    CAS:
    <p>SC-560 is a member of the diaryl heterocycle class of cyclooxygenase (COX) inhibitors.</p>
    Formula:C17H12ClF3N2O
    Purezza:99.97%
    Colore e forma:Solid
    Peso molecolare:352.74
  • RK33

    CAS:
    <p>"RK33 is a DDX3 inhibitor causing G1 arrest, apoptosis, and radiation sensitization in DDX3-overexpressing cells."</p>
    Formula:C23H20N6O3
    Purezza:99.04% - 99.72%
    Colore e forma:Solid
    Peso molecolare:428.44
  • Gnetol

    CAS:
    <p>Gnetol inhibits butyrylcholinesterase (IC50: 1.3 μM), tyrosinase, melanin synthesis in B16 cells, and AA-induced platelet aggregation.</p>
    Formula:C14H12O4
    Purezza:98.55% - ≥95%
    Colore e forma:Solid
    Peso molecolare:244.24
  • Columbin

    CAS:
    <p>Columbin: anti-inflammatory, prevents colon cancer, inhibits PLA2 in RBC dose-dependently.</p>
    Formula:C20H22O6
    Purezza:99.34% - 99.74%
    Colore e forma:Solid
    Peso molecolare:358.39
  • S-(+)-Marmesin

    CAS:
    <p>S-(+)-Marmesin (marmesin) is a coumarin originally isolated from the mature bark of A. marmelos,exhibiting COX-2/5-LOX dual inhibitory activity.</p>
    Formula:C14H14O4
    Purezza:98.00% - ≥98%
    Colore e forma:Solid
    Peso molecolare:246.26