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COX

COX

Gli inibitori della cicloossigenasi (COX) sono composti che bloccano l'attività degli enzimi COX, coinvolti nella produzione di prostaglandine, mediatori chiave dell'infiammazione e del dolore. In neuroscienze, gli inibitori della COX sono studiati per il loro potenziale nel ridurre la neuroinfiammazione, implicata in varie malattie neurodegenerative come l'Alzheimer, il Parkinson e la sclerosi multipla. Inibendo la COX, questi composti possono aiutare a mitigare i processi infiammatori nel cervello e a proteggere dai danni neuronali. Presso CymitQuimica, offriamo una gamma di inibitori della COX per supportare la tua ricerca sulla neuroinfiammazione, la gestione del dolore e le malattie neurodegenerative.

Trovati 561 prodotti di "COX"

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  • Naproxen etemesil
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    Naproxen etemesil

    CAS:
    <p>Naproxen, a COX-1/2 inhibitor, has IC50s of 8.72/5.15 μM. Its prodrug, naproxen etemesil, is lipophilic and converts to active form upon absorption.</p>
    Formula:C17H20O5S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:336.4

    Ref: TM-T16272

  • ATB-337
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    ATB-337

    CAS:
    <p>S-Diclofenac, an NSAID with H2S-releasing moiety, protects gastric mucosa while inhibiting prostaglandins.</p>
    Formula:C23H15Cl2NO2S3
    Colore e forma:Solid
    Peso molecolare:504.47

    Ref: TM-T21939

  • COX-2-IN-1
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    COX-2-IN-1

    CAS:
    <p>COX-2-IN-1 is a potent and selective COX-2 inhibitor (IC50: 3.9 μM).</p>
    Formula:C18H14ClF3N4O2S
    Purezza:>99.99%
    Colore e forma:Solid
    Peso molecolare:442.84

    Ref: TM-T10033

  • Insulin levels modulator
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    Insulin levels modulator

    CAS:
    <p>Insulin level regulators can be used to treat diabetes.</p>
    Formula:C21H23N7OS
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:421.52

    Ref: TM-T11660

  • COX-2-IN-28
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    COX-2-IN-28

    CAS:
    <p>COX-2-IN-28 is a potent and selective COX-2 inhibitor capable of acting on COX-2 (IC50: 0.054 μM), 15-LOX (IC50: 2.14 μM) and COX-1 (IC50: 13.21 μM).</p>
    Formula:C30H27N7S3
    Colore e forma:Solid
    Peso molecolare:581.78

    Ref: TM-T64109

  • (-)-Ibuprofenamide
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    (-)-Ibuprofenamide

    CAS:
    <p>(-)-Ibuprofenamide is an amide prodrug of Ibuprofen with anti-inflammatory activity.</p>
    Formula:C13H19NO
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:205.3

    Ref: TM-T11605

  • Naproxcinod
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    Naproxcinod

    CAS:
    <p>Naproxcinod is a derivative of naproxen, analgesic and anti-inflammatory, a COX-inhibitory nitric oxide donor (CINOD), osteoarthritis and inflammatory.</p>
    Formula:C18H21NO6
    Colore e forma:Solid
    Peso molecolare:347.36

    Ref: TM-T33595

  • GW-406381
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    GW-406381

    CAS:
    <p>GW-406381 is a highly selective COX-2 inhibitor peripherally and centrally, reducing spontaneous ectopic discharges following chronic compressive injury.</p>
    Formula:C21H19N3O3S
    Purezza:99.54%
    Colore e forma:Solid
    Peso molecolare:393.46

    Ref: TM-T15449

  • ADU-S100
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    ADU-S100

    CAS:
    <p>ADU-S100 (MIW815) is a STING agonist that significantly induces the production of IFN-β,TNF-α,IL-6,and MCP-1,induces TBK1 and IRF3 phosphorylation,antitumour.</p>
    Formula:C20H24N10O10P2S2
    Purezza:99.83%
    Colore e forma:Solid
    Peso molecolare:690.54

    Ref: TM-T10252L3

  • Anti-inflammatory agent 56
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    Anti-inflammatory agent 56

    CAS:
    <p>Anti-inflammatory agent 56 (Compound 9), a selective COX-2 inhibitor with an IC50 of 0.54 μM, exhibits anti-oxidant and anti-inflammatory properties by</p>
    Formula:C21H15F3N4O4S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:476.43

    Ref: TM-T79670

  • LY 178002
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    LY 178002

    CAS:
    <p>LY 178002 inhibits 5-LPO (IC50: 0.6 μM), PLA2, and LTB4 production; weak on cyclooxygenase.</p>
    Formula:C18H25NO2S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:319.46

    Ref: TM-T15825

  • COX/5-LO-IN-1
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    COX/5-LO-IN-1

    CAS:
    <p>COX/5-LO-IN-1 is a cyclooxygenase and 5-lipoxygenase (5-LO) inhibitor, and used for inflammatory and allergic disease states.</p>
    Formula:C16H15FN2O2S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:318.37

    Ref: TM-T13263

  • COX-2-IN-16
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    COX-2-IN-16

    CAS:
    <p>COX-2-IN-16: potent, selective oral COX-2 blocker, IC50=102 μM, reduces NO, anti-inflammatory.</p>
    Formula:C19H12BrN3O2
    Colore e forma:Solid
    Peso molecolare:394.22

    Ref: TM-T61821

  • Thiazolinobutazone
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    Thiazolinobutazone

    CAS:
    <p>Thiazolinobutazone is the 2-amino-2-thiazoline salt of phenylbutazone.</p>
    Formula:C22H26N4O2S
    Colore e forma:Solid
    Peso molecolare:410.53

    Ref: TM-T34846

  • COX-2-IN-14
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    COX-2-IN-14

    CAS:
    <p>COX-2-IN-14 (2a) is a potent, selective COX-2 inhibitor with high affinity and notable anti-inflammatory effects in mice.</p>
    Formula:C18H18N4O6
    Colore e forma:Solid
    Peso molecolare:386.364

    Ref: TM-T61711

  • Apricoxib
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    Apricoxib

    CAS:
    <p>Apricoxib: oral NSAID with antiangiogenic, antineoplastic properties; inhibits COX-2, may reduce tumor growth and angiogenesis.</p>
    Formula:C19H20N2O3S
    Colore e forma:Solid
    Peso molecolare:356.44

    Ref: TM-T70018

  • Anti-inflammatory agent 8
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    Anti-inflammatory agent 8

    CAS:
    <p>Anti-inflammatory agent 8 targets COX-2 over COX-1, IC50 of 0.09 nM, orally bioavailable.</p>
    Formula:C18H15N5OS2
    Colore e forma:Solid
    Peso molecolare:381.47

    Ref: TM-T61637

  • SC57666
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    SC57666

    CAS:
    <p>SC57666 is a highly selective COX2 inhibitor (IC50 at 26 nM) that shows no activity against COX1.</p>
    Formula:C18H17FO2S
    Purezza:98.83%
    Colore e forma:Solid
    Peso molecolare:316.39

    Ref: TM-T12860

  • COX-2-IN-32
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    COX-2-IN-32

    CAS:
    <p>COX-2-IN-32 (Compound 2f) is a dual inhibitor of iNOS and COX-2, known to downregulate NF-κB expression.</p>
    Formula:C25H24O6
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:420.45

    Ref: TM-T79130

  • Naproxen glucuronide
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    Naproxen glucuronide

    CAS:
    <p>Naproxen glucuronide: NSAID, propionic class, eases pain, fever, inflammation. Nonselective COX blocker.</p>
    Formula:C20H22O9
    Colore e forma:Solid
    Peso molecolare:406.38

    Ref: TM-T69267