COX
Gli inibitori della cicloossigenasi (COX) sono composti che bloccano l'attività degli enzimi COX, coinvolti nella produzione di prostaglandine, mediatori chiave dell'infiammazione e del dolore. In neuroscienze, gli inibitori della COX sono studiati per il loro potenziale nel ridurre la neuroinfiammazione, implicata in varie malattie neurodegenerative come l'Alzheimer, il Parkinson e la sclerosi multipla. Inibendo la COX, questi composti possono aiutare a mitigare i processi infiammatori nel cervello e a proteggere dai danni neuronali. Presso CymitQuimica, offriamo una gamma di inibitori della COX per supportare la tua ricerca sulla neuroinfiammazione, la gestione del dolore e le malattie neurodegenerative.
Trovati 602 prodotti per "COX".
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Roburic acid
CAS:Roburic acid and phenethyl-trans-ferulate inhibit COX-1 and COX-2.Formula:C30H48O2Purezza:98.76% - 99.98%Colore e forma:White SolidPeso molecolare:440.70Cadonilimab
CAS:Cadonilimab (AK104) is a tetravalent PD-1/CTLA-4 bispecific humanised antibody that activates T cells by enhancing IL-2 and IFN-γ secretion.Purezza:95% - 95%Colore e forma:Transparent LiquidPeso molecolare:198.64 kDaAspirin DL-lysine
CAS:Aspirin DL-lysine: a water-soluble, injectable NSAID that may also hinder cancer growth.Formula:C15H22N2O6Colore e forma:SolidPeso molecolare:326.35Anti-IL-12 p70 Antibody (20C2)
Anti-IL-12 p70 Antibody (20C2), an IgG1 monoclonal, suppresses interferon-gamma, IL-12-mediated inflammation, paired with a Rat IgG1 kappa control.Purezza:95%Colore e forma:Transparent LiquidPeso molecolare:150 kDaImidazole Salicylate
CAS:Imidazole Salicylate, a non-steroidal anti-inflammatory drug, has limited inhibitory effects on prostaglandin synthesis.Formula:C10H10N2O3Purezza:98%Colore e forma:SolidPeso molecolare:206.2Fontolizumab
CAS:Fontolizumab (HuZAF) is a humanised IgG1 monoclonal anti-IFN-gamma (IFN-γ) antibody for the study of Crohn's disease.Purezza:95%Colore e forma:Transparent LiquidPeso molecolare:~150 kDaClonixin
CAS:Formula:C13H11ClN2O2Purezza:>98.0%(T)(HPLC)Colore e forma:White to Light yellow powder to crystalPeso molecolare:262.69Ketorolac Tromethamine
CAS:Formula:C15H13NO3·C4H11NO3Purezza:>98.0%(T)(HPLC)Colore e forma:White to Light yellow powder to crystalPeso molecolare:376.41Indometacin Farnesil
CAS:Formula:C34H40ClNO4Purezza:>98.0%(HPLC)Colore e forma:Light yellow to Yellow to Orange clear liquidPeso molecolare:562.154-AcetaMido-D3-antipyrine
CAS:4-AcetaMido-D3-antipyrine is a deuterated compound of 4-AcetaMido-antipyrine. 4-AcetaMido-antipyrine (Fr213003) has a CAS number of 83-15-8.Formula:C13H12D3N3O2Colore e forma:SolidPeso molecolare:248.30Nepafenac-D5
CAS:Nepafenac D5 is the deuterium labeled Nepafenac, which is a selective inhibitor of COX-2 .Formula:C15H14N2O2Purezza:98%Colore e forma:SolidPeso molecolare:259.31Ketorolac-D5
CAS:Ketorolac-d5 is a deuterated compound of ketorolac for isotope tracing. Ketorolac is a non-steroidal anti-inflammatory agent and inhibitor of COX-1 and COX-2.Formula:C15H8D5NO3Purezza:98.99%Colore e forma:White SolidPeso molecolare:260.3AHR-10037
CAS:AHR-10037, a NSAID, offers pain relief, fever reduction, safety, and low stomach risk, acting as a prodrug for COX inhibitors.Formula:C15H13ClN2O2Purezza:98%Colore e forma:SolidPeso molecolare:288.73Sampeginterferon β-1a
CAS:Sampeginterferon beta-1a (BCD-054), a pegylated IFNβ-1a, is evaluated for its potential in research addressing remitting multiple sclerosis [1] [2].Colore e forma:LiquidAmfenac
CAS:Amfenac promotes apoptosis in ARPE-19 cell culture.Formula:C15H13NO3Colore e forma:SolidPeso molecolare:255.27Pelubiprofen
CAS:Pelubiprofen is a non-steroidal anti-inflammatory agent and a COX-2 inhibitor, which effectively reduces PGE(2) production by inhibiting COX activity.Formula:C16H18O3Purezza:99.79%Colore e forma:SolidPeso molecolare:258.31MK-0703
CAS:MK-0703 is a selective cyclooxygenase-2 inhibitor.Formula:C17H22O5SPurezza:98%Colore e forma:SolidPeso molecolare:338.42Prostaglandin G/H synthase 1 inhibitor
CAS:Prostaglandin G/H synthase 1 inhibitor (CP 74006) is a selective D5D inhibitor with an IC(50) value of 20 nM.Formula:C13H11ClN2OPurezza:99.76%Colore e forma:White SolidPeso molecolare:246.69APHS
CAS:APHS is a cyclooxygenase-2 (COX-2) inhibitor with anti-inflammatory action. It also more potent than aspirin in the inhibition of COX-1.Formula:C15H18O2SColore e forma:SolidPeso molecolare:262.37PD 127443
CAS:PD 127443 is a Leukotriene B4 antagonist, it is also a dual inhibitor of cyclooxygenase and 5-lipoxygenase.Formula:C20H28N2OColore e forma:SolidPeso molecolare:312.45Timegadine
CAS:Timegadine is a competitive inhibitor of COX and lipo-oxygenase, with IC50s ranging from 5 nM (washed rabbit platelets) to 20 μM (rat brain) for COX and 100 μMFormula:C20H23N5SPurezza:98%Colore e forma:SolidPeso molecolare:365.5Naproxen ethyl ester
CAS:Naproxen ethyl ester, an NSAID similar to ibuprofen, reduces pain, fever, and inflammation. It's a non-selective COX inhibitor.Formula:C16H18O3Colore e forma:SolidPeso molecolare:258.31AL-8417
CAS:AL-8417 is an enzyme inhibitor with antioxidant, anti-inflammatory, and cytostatic properties; prevents vitrectomy-induced lens alterations.Formula:C29H34O5Purezza:98%Colore e forma:SolidPeso molecolare:462.58Nitroflurbiprofen
CAS:Nitroflurbiprofen (Nitroxybutyl flurbiprofen) is a NO-releasing COX inhibitor and modulates the increased intrahepatic vascular tone in portal hypertensiveFormula:C19H20FNO5Purezza:99.88%Colore e forma:SolidPeso molecolare:361.36SC57666
CAS:SC57666 is a highly selective COX2 inhibitor (IC50 at 26 nM) that shows no activity against COX1.Formula:C18H17FO2SPurezza:98.83%Colore e forma:SolidPeso molecolare:316.39Ref: TM-T12860
1mg110,00€5mg231,00€1mL*10mM (DMSO)255,00€10mg370,00€25mg632,00€50mg827,00€100mg1.071,00€200mg1.431,00€LY 178002
CAS:LY 178002 inhibits 5-LPO (IC50: 0.6 μM), PLA2, and LTB4 production; weak on cyclooxygenase.Formula:C18H25NO2SPurezza:98%Colore e forma:SolidPeso molecolare:319.46K-80001
CAS:K-80001 is a selective RXRα ligand and a COX-1/2 inhibitor, exhibiting IC50 values of 82.9μM for RXRα, 3.4μM for COX-1, and 1.2μM for COX-2, respectively [1].Formula:C20H17FO2Colore e forma:SolidPeso molecolare:308.35COX-2-IN-21
CAS:COX-2-IN-21 (Compound 5c) is an orally active, selective COX-2 inhibitor (IC50: 0.039 μM). COX-2-IN-21 has good anti-inflammatory potential.Formula:C21H22N6O4Colore e forma:SolidPeso molecolare:422.44COX/5-LOX-IN-1
CAS:Compound 6b is a potent dual inhibitor of COX/5-LOX with IC50s: 1.07μM (COX-1), 0.55μM (COX-2), 0.28μM (5-LOX) for inflammation research.Formula:C18H30O3Colore e forma:SolidPeso molecolare:294.43SC58451
CAS:SC58451 is a novel potent, orally active and selective COX-2 inhibitor.SC58451 showed anti-inflammatory activity in a rat model of arthritis.Formula:C20H19FO2SPurezza:>99.99%Colore e forma:White SolidPeso molecolare:342.43Anti-inflammatory agent 56
CAS:Anti-inflammatory agent 56 (Compound 9), a selective COX-2 inhibitor with an IC50 of 0.54 μM, exhibits anti-oxidant and anti-inflammatory properties byFormula:C21H15F3N4O4SPurezza:98%Colore e forma:SolidPeso molecolare:476.43Enflicoxib
CAS:Enflicoxib is an effective treatment for canine osteoarthritis pain and inflammation, with faster onset than mavacoxib, improving veterinary outcomes.Formula:C16H12F5N3O2SPurezza:99.27% - 99.88%Colore e forma:White SolidPeso molecolare:405.34COX-2-IN-20
CAS:COX-2-IN-20 (Compound 5d) is a selective and orally active inhibitor of COX-2 (IC 50 = 17.9 nM) with anti-inflammatory activity [1].Formula:C11H9ClFN3O2Colore e forma:SolidPeso molecolare:269.66Pifoxime
CAS:Pifoxime: a NSAID with COX-1/2 inhibition, used in anti-inflammatory treatment and neuropsychiatric studies.Formula:C15H20N2O3Colore e forma:SolidPeso molecolare:276.33Feprazone
CAS:Feprazone (DA-2370) possesses anti-inflammatory and antiadipogenic properties. Feprazone can be used in studies about the treatment of joint and muscular pain.Formula:C20H20N2O2Purezza:99.89% - 99.90%Colore e forma:SolidPeso molecolare:320.39COX-2-IN-16
CAS:COX-2-IN-16: potent, selective oral COX-2 blocker, IC50=102 μM, reduces NO, anti-inflammatory.Formula:C19H12BrN3O2Colore e forma:SolidPeso molecolare:394.22Thiazolinobutazone
CAS:Thiazolinobutazone is the 2-amino-2-thiazoline salt of phenylbutazone.Formula:C22H26N4O2SColore e forma:SolidPeso molecolare:410.53COX-2-IN-14
CAS:COX-2-IN-14 (2a) is a potent, selective COX-2 inhibitor with high affinity and notable anti-inflammatory effects in mice.Formula:C18H18N4O6Colore e forma:SolidPeso molecolare:386.364COX-2-IN-2
CAS:COX-2-IN-2 selectively inhibits COX2 (IC50: 0.24 μM); COX-2-IN-1 offers anti-inflammatory and pain relief.Formula:C17H12FN3O2SPurezza:97.62%Colore e forma:SolidPeso molecolare:341.36Ref: TM-T10032
1mg163,00€5mg394,00€1mL*10mM (DMSO)401,00€10mg632,00€25mg1.260,00€50mg2.008,00€100mg2.665,00€COX-2-IN-26
CAS:COX-2-IN-26: Oral, selective COX-2 inhibitor, low IC50s; anti-inflammatory with GI safety.Formula:C23H21N7OS3Colore e forma:SolidPeso molecolare:507.65Loxoprofenol-SRS tromethamine
CAS:Loxoprofenol-SRS tromethamine (HR1405-01), a metabolite of Loxoprofen, is a safe IV NSAID with strong anti-inflammatory and pain relief properties.Formula:C19H31NO6Colore e forma:SolidPeso molecolare:369.45FR-188582
CAS:FR-188582 is a highly selective cyclooxygenase (COX)-2 inhibitor (IC50: 17 nM).Formula:C16H13ClN2O2SPurezza:98%Colore e forma:SolidPeso molecolare:332.8AHR-6293
CAS:AHR-6293 is used to distinguishing the effect of anti-platelet aggregating drug properties and the effect of anti-inflammatory properties.Formula:C15H12ClNO3Colore e forma:SolidPeso molecolare:289.71Glucametacine
CAS:Glucametacine is an anti-inflammatory agent.Formula:C25H27ClN2O8Colore e forma:SolidPeso molecolare:518.94Naproxen etemesil
CAS:Naproxen, a COX-1/2 inhibitor, has IC50s of 8.72/5.15 μM. Its prodrug, naproxen etemesil, is lipophilic and converts to active form upon absorption.Formula:C17H20O5SPurezza:98%Colore e forma:SolidPeso molecolare:336.4ASP-6537
CAS:ASP-6537 is a selective and reversible inhibitor of cyclooxygenase-1.Formula:C17H17N3O3Purezza:98%Colore e forma:SolidPeso molecolare:311.34Flosulide
CAS:Flosulide is an effective selective COX-2 inhibitor for the treatment of inflammatory diseases.Formula:C16H13F2NO4SPurezza:98%Colore e forma:SolidPeso molecolare:353.34NCX 466
CAS:cyclooxygenase (COX)-inhibiting nitric oxide (NO) donorFormula:C20H24N2O9Purezza:98%Colore e forma:SolidPeso molecolare:436.41Etoricoxib HCl
CAS:Etoricoxib HCl is a synthetic NSAID that inhibits COX-2, blocking prostaglandin production.Formula:C18H16Cl2N2O2SColore e forma:SolidPeso molecolare:395.30Carpro-AM1
CAS:Carpro-AM1, dual FAAH/COX inhibitor, IC50: 94 nM.Formula:C21H18ClN3OColore e forma:SolidPeso molecolare:363.84
