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COX

COX

Gli inibitori della cicloossigenasi (COX) sono composti che bloccano l'attività degli enzimi COX, coinvolti nella produzione di prostaglandine, mediatori chiave dell'infiammazione e del dolore. In neuroscienze, gli inibitori della COX sono studiati per il loro potenziale nel ridurre la neuroinfiammazione, implicata in varie malattie neurodegenerative come l'Alzheimer, il Parkinson e la sclerosi multipla. Inibendo la COX, questi composti possono aiutare a mitigare i processi infiammatori nel cervello e a proteggere dai danni neuronali. Presso CymitQuimica, offriamo una gamma di inibitori della COX per supportare la tua ricerca sulla neuroinfiammazione, la gestione del dolore e le malattie neurodegenerative.

Trovati 562 prodotti di "COX"

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  • SC57666
    Targetmol
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    SC57666

    CAS:
    <p>SC57666 is a highly selective COX2 inhibitor (IC50 at 26 nM) that shows no activity against COX1.</p>
    Formula:C18H17FO2S
    Purezza:98.83%
    Colore e forma:Solid
    Peso molecolare:316.39

    Ref: TM-T12860

  • FR-188582
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    FR-188582

    CAS:
    <p>FR-188582 is a highly selective cyclooxygenase (COX)-2 inhibitor (IC50: 17 nM).</p>
    Formula:C16H13ClN2O2S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:332.8

    Ref: TM-T15345

  • Anti-inflammatory agent 56
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    Anti-inflammatory agent 56

    CAS:
    <p>Anti-inflammatory agent 56 (Compound 9), a selective COX-2 inhibitor with an IC50 of 0.54 μM, exhibits anti-oxidant and anti-inflammatory properties by</p>
    Formula:C21H15F3N4O4S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:476.43

    Ref: TM-T79670

  • COX/5-LO-IN-1
    Targetmol
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    COX/5-LO-IN-1

    CAS:
    <p>COX/5-LO-IN-1 is a cyclooxygenase and 5-lipoxygenase (5-LO) inhibitor, and used for inflammatory and allergic disease states.</p>
    Formula:C16H15FN2O2S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:318.37

    Ref: TM-T13263

  • MK-0703
    Targetmol
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    MK-0703

    CAS:
    <p>MK-0703 is a selective cyclooxygenase-2 inhibitor.</p>
    Formula:C17H22O5S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:338.42

    Ref: TM-T28052

  • COX-2/15-LOX-IN-1
    Targetmol
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    COX-2/15-LOX-IN-1

    CAS:
    <p>COX-2/15-LOX-IN-1 is a dual inhibitor for COX-2/15-LOX with anti-inflammatory properties (IC50: COX-1 10.65μM, COX-2 0.075μM, 15-LOX 2.98μM).</p>
    Formula:C21H21N7S3
    Colore e forma:Solid
    Peso molecolare:467.63

    Ref: TM-T62998

  • COX-2-IN-17
    Targetmol
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    COX-2-IN-17

    CAS:
    <p>COX-2-IN-17 is a potent, blood-brain barrier permeable COX-2 (cyclooxygenase-2) inhibitor (IC50: 0.02 μM) with anti-inflammatory and analgesic activity.</p>
    Formula:C20H23ClN6O2
    Colore e forma:Solid
    Peso molecolare:414.89

    Ref: TM-T62142

  • COX-2-IN-23
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    COX-2-IN-23

    CAS:
    <p>COX-2-IN-23 selectively inhibits COX-2 (IC50=0.28μM), weakly affects COX-1 (IC50=20.14μM), and has anti-inflammatory and low ulcerogenic properties.</p>
    Formula:C24H25N5O3S2
    Colore e forma:Solid
    Peso molecolare:495.62

    Ref: TM-T63348

  • COX-1/2-IN-3
    Targetmol
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    COX-1/2-IN-3

    CAS:
    <p>COX-1/2-IN-3 (Compound 7a) is a dual inhibitor of COX-1 and COX-2. COX-1/2-IN-3 has anti-inflammatory activity with low toxicity [1].</p>
    Formula:C14H8N2O8
    Colore e forma:Solid
    Peso molecolare:332.22

    Ref: TM-T60992

  • COX-1/2-IN-1
    Targetmol
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    COX-1/2-IN-1

    CAS:
    <p>"COX-1/2-IN-2: Strong dual inhibitor of COX-1 (IC50 = 13.9 μM) and COX-2 (IC50 = 6.4 μM)."</p>
    Formula:C15H10BrClN2O
    Colore e forma:Solid
    Peso molecolare:349.61

    Ref: TM-T61196

  • K-80001
    Targetmol
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    K-80001

    CAS:
    <p>K-80001 is a selective RXRα ligand and a COX-1/2 inhibitor, exhibiting IC50 values of 82.9μM for RXRα, 3.4μM for COX-1, and 1.2μM for COX-2, respectively [1].</p>
    Formula:C20H17FO2
    Colore e forma:Solid
    Peso molecolare:308.35

    Ref: TM-T79181

  • Anti-inflammatory agent 8
    Targetmol
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    Anti-inflammatory agent 8

    CAS:
    <p>Anti-inflammatory agent 8 targets COX-2 over COX-1, IC50 of 0.09 nM, orally bioavailable.</p>
    Formula:C18H15N5OS2
    Colore e forma:Solid
    Peso molecolare:381.47

    Ref: TM-T61637

  • Apricoxib
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    Apricoxib

    CAS:
    <p>Apricoxib: oral NSAID with antiangiogenic, antineoplastic properties; inhibits COX-2, may reduce tumor growth and angiogenesis.</p>
    Formula:C19H20N2O3S
    Colore e forma:Solid
    Peso molecolare:356.44

    Ref: TM-T70018

  • COX-2/sEH-IN-1
    Targetmol
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    COX-2/sEH-IN-1

    CAS:
    <p>COX-2/sEH-IN-1, oral dual inhibitor: COX-2 (IC50=1.24 μM), sEH (IC50=0.40 μM); boosts anti-inflammatory action, cuts heart risk.</p>
    Formula:C23H18F3N5O3S
    Colore e forma:Solid
    Peso molecolare:501.48

    Ref: TM-T63398

  • Naproxen glucuronide
    Targetmol
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    Naproxen glucuronide

    CAS:
    <p>Naproxen glucuronide: NSAID, propionic class, eases pain, fever, inflammation. Nonselective COX blocker.</p>
    Formula:C20H22O9
    Colore e forma:Solid
    Peso molecolare:406.38

    Ref: TM-T69267

  • AL-8417
    Targetmol
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    AL-8417

    CAS:
    <p>AL-8417 is an enzyme inhibitor with antioxidant, anti-inflammatory, and cytostatic properties; prevents vitrectomy-induced lens alterations.</p>
    Formula:C29H34O5
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:462.58

    Ref: TM-T23697

  • PD 127443
    Targetmol
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    PD 127443

    CAS:
    <p>PD 127443 is a Leukotriene B4 antagonist, it is also a dual inhibitor of cyclooxygenase and 5-lipoxygenase.</p>
    Formula:C20H28N2O
    Colore e forma:Solid
    Peso molecolare:312.45

    Ref: TM-T28325

  • COX-2-IN-32
    Targetmol
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    COX-2-IN-32

    CAS:
    <p>COX-2-IN-32 (Compound 2f) is a dual inhibitor of iNOS and COX-2, known to downregulate NF-κB expression.</p>
    Formula:C25H24O6
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:420.45

    Ref: TM-T79130

  • Thiazolinobutazone
    Targetmol
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    Thiazolinobutazone

    CAS:
    <p>Thiazolinobutazone is the 2-amino-2-thiazoline salt of phenylbutazone.</p>
    Formula:C22H26N4O2S
    Colore e forma:Solid
    Peso molecolare:410.53

    Ref: TM-T34846

  • ASP-6537
    Targetmol
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    ASP-6537

    CAS:
    <p>ASP-6537 is a selective and reversible inhibitor of cyclooxygenase-1.</p>
    Formula:C17H17N3O3
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:311.34

    Ref: TM-T23758

  • COX/5-LOX-IN-1
    Targetmol
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    COX/5-LOX-IN-1

    CAS:
    <p>Compound 6b is a potent dual inhibitor of COX/5-LOX with IC50s: 1.07μM (COX-1), 0.55μM (COX-2), 0.28μM (5-LOX) for inflammation research.</p>
    Formula:C18H30O3
    Colore e forma:Solid
    Peso molecolare:294.43

    Ref: TM-T60630

  • Pifoxime
    Targetmol
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    Pifoxime

    CAS:
    <p>Pifoxime: a NSAID with COX-1/2 inhibition, used in anti-inflammatory treatment and neuropsychiatric studies.</p>
    Formula:C15H20N2O3
    Colore e forma:Solid
    Peso molecolare:276.33

    Ref: TM-T69473

  • COX-2-IN-16
    Targetmol
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    COX-2-IN-16

    CAS:
    <p>COX-2-IN-16: potent, selective oral COX-2 blocker, IC50=102 μM, reduces NO, anti-inflammatory.</p>
    Formula:C19H12BrN3O2
    Colore e forma:Solid
    Peso molecolare:394.22

    Ref: TM-T61821

  • COX-2/5-LOX-IN-3
    Targetmol
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    COX-2/5-LOX-IN-3

    CAS:
    <p>COX-2/5-LOX-IN-3 inhibits COX-2/5-LOX with IC50s: COX-1 45.73μM, COX-2 5.45μM, 5-LOX 4.33μM; promising for inflammation research.</p>
    Formula:C17H16ClN3O2S
    Colore e forma:Solid
    Peso molecolare:361.85

    Ref: TM-T61352

  • ATB-337
    Targetmol
    + Info

    ATB-337

    CAS:
    <p>S-Diclofenac, an NSAID with H2S-releasing moiety, protects gastric mucosa while inhibiting prostaglandins.</p>
    Formula:C23H15Cl2NO2S3
    Colore e forma:Solid
    Peso molecolare:504.47

    Ref: TM-T21939

  • Flosulide
    Targetmol
    + Info

    Flosulide

    CAS:
    <p>Flosulide is an effective selective COX-2 inhibitor for the treatment of inflammatory diseases.</p>
    Formula:C16H13F2NO4S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:353.34

    Ref: TM-T11296

  • AHR-6293
    Targetmol
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    AHR-6293

    CAS:
    <p>AHR-6293 is used to distinguishing the effect of anti-platelet aggregating drug properties and the effect of anti-inflammatory properties.</p>
    Formula:C15H12ClNO3
    Colore e forma:Solid
    Peso molecolare:289.71

    Ref: TM-T23684

  • NCX 466
    Targetmol
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    NCX 466

    CAS:
    <p>cyclooxygenase (COX)-inhibiting nitric oxide (NO) donor</p>
    Formula:C20H24N2O9
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:436.41

    Ref: TM-T23062

  • Etoricoxib HCl
    Targetmol
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    Etoricoxib HCl

    CAS:
    <p>Etoricoxib HCl is a synthetic NSAID that inhibits COX-2, blocking prostaglandin production.</p>
    Formula:C18H16Cl2N2O2S
    Colore e forma:Solid
    Peso molecolare:395.30

    Ref: TM-T1574L

  • Lobeglitazone Sulfate
    Targetmol
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    Lobeglitazone Sulfate

    CAS:
    <p>Lobeglitazone Sulfate (CKD-501) is an anti-inflammatory thiazolidinedione that prevents NLRP3 inflammasome activation and is used in T2DM research.</p>
    Formula:C24H26N4O9S2
    Purezza:98.69%
    Colore e forma:Solid
    Peso molecolare:578.61

    Ref: TM-T27841

  • LY 25648
    Targetmol
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    LY 25648

    CAS:
    <p>LY 25648 is an antagonist of leukotriene B4.</p>
    Formula:C19H27NO2S
    Colore e forma:Solid
    Peso molecolare:333.49

    Ref: TM-T27906

  • ZXX2-77
    Targetmol
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    ZXX2-77

    CAS:
    <p>ZXX2-77 is a cyclooxygenase-1 inhibitor.</p>
    Formula:C13H13ClN2O2S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:296.77

    Ref: TM-T24464

  • LY 150310
    Targetmol
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    LY 150310

    CAS:
    <p>LY 150310, a histamine H1-receptor antagonist, can alter prostanoid concentrations in vitro and in vivo.</p>
    Formula:C13H14N2
    Colore e forma:Solid
    Peso molecolare:198.26

    Ref: TM-T27875

  • PC407-ws
    Targetmol
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    PC407-ws

    CAS:
    <p>PC407-ws is a water-soluble novel COX-2 inhibitor.</p>
    Formula:C24H18F3N3Na2O5S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:563.46

    Ref: TM-T24600

  • Isonixin
    Targetmol
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    Isonixin

    CAS:
    <p>Isonixin is used for the treatment of inflammation and pain associated with musculoskeletal and joint disorders.</p>
    Formula:C14H14N2O2
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:242.27

    Ref: TM-T27633

  • Prostaglandin G/H synthase 1 inhibitor
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    Prostaglandin G/H synthase 1 inhibitor

    CAS:
    <p>Prostaglandin G/H synthase 1 inhibitor (CP 74006) is a selective D5D inhibitor with an IC(50) value of 20 nM.</p>
    Formula:C13H11ClN2O
    Purezza:99.76%
    Colore e forma:Solid
    Peso molecolare:246.69

    Ref: TM-T27066

  • Tenosal
    Targetmol
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    Tenosal

    CAS:
    <p>Tenosal obtained by esterifying salicylic acid with 2-thiophene-carboxylic acid, and with analgesic and antipyretic properties, anti-inflammatory.</p>
    Formula:C12H8O4S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:248.25

    Ref: TM-T13122

  • LY 178002
    Targetmol
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    LY 178002

    CAS:
    <p>LY 178002 inhibits 5-LPO (IC50: 0.6 μM), PLA2, and LTB4 production; weak on cyclooxygenase.</p>
    Formula:C18H25NO2S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:319.46

    Ref: TM-T15825

  • L 748780
    Targetmol
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    L 748780

    CAS:
    <p>L 748780 is a selective inducible COX-2 inhibitor.</p>
    Formula:C19H14Cl3NO4
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:426.68

    Ref: TM-T24360

  • Eicosatetraynoic acid
    Targetmol
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    Eicosatetraynoic acid

    CAS:
    <p>ETYA activates PPARα/γ at 10μM, inhibits cyclooxygenase (ID50=8μM) and lipoxygenase (ID50=4μM).</p>
    Formula:C20H24O2
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:296.4

    Ref: TM-T11169

  • COX-2-IN-20
    Targetmol
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    COX-2-IN-20

    CAS:
    <p>COX-2-IN-20 (Compound 5d) is a selective and orally active inhibitor of COX-2 (IC 50 = 17.9 nM) with anti-inflammatory activity [1].</p>
    Formula:C11H9ClFN3O2
    Colore e forma:Solid
    Peso molecolare:269.66

    Ref: TM-T60464

  • Feprazone
    Targetmol
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    Feprazone

    CAS:
    <p>Feprazone (DA-2370) possesses anti-inflammatory and antiadipogenic properties. Feprazone can be used in studies about the treatment of joint and muscular pain.</p>
    Formula:C20H20N2O2
    Purezza:99.6% - 99.89%
    Colore e forma:Solid
    Peso molecolare:320.39

    Ref: TM-T7722

  • Tilmacoxib
    Targetmol
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    Tilmacoxib

    CAS:
    <p>Tilmacoxib is a highly selective, time-dependent, and irreversible inhibitor of human COX-2 ( IC50: 85 nM in an enzyme assay).</p>
    Formula:C16H19FN2O3S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:338.4

    Ref: TM-T15630

  • COX-2-IN-1
    Targetmol
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    COX-2-IN-1

    CAS:
    <p>COX-2-IN-1 is a potent and selective COX-2 inhibitor (IC50: 3.9 μM).</p>
    Formula:C18H14ClF3N4O2S
    Purezza:>99.99%
    Colore e forma:Solid
    Peso molecolare:442.84

    Ref: TM-T10033

  • Carpro-AM1
    Targetmol
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    Carpro-AM1

    CAS:
    <p>Carpro-AM1, dual FAAH/COX inhibitor, IC50: 94 nM.</p>
    Formula:C21H18ClN3O
    Colore e forma:Solid
    Peso molecolare:363.84

    Ref: TM-T61380

  • Enflicoxib
    Targetmol
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    Enflicoxib

    CAS:
    <p>Enflicoxib is an effective treatment for canine osteoarthritis pain and inflammation, with faster onset than mavacoxib, improving veterinary outcomes.</p>
    Formula:C16H12F5N3O2S
    Purezza:99.88%
    Colore e forma:Solid
    Peso molecolare:405.34

    Ref: TM-T27233

  • Insulin levels modulator
    Targetmol
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    Insulin levels modulator

    CAS:
    <p>Insulin level regulators can be used to treat diabetes.</p>
    Formula:C21H23N7OS
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:421.52

    Ref: TM-T11660

  • SC58451
    Targetmol
    + Info

    SC58451

    CAS:
    <p>SC58451 is a novel potent, orally active and selective COX-2 inhibitor.SC58451 showed anti-inflammatory activity in a rat model of arthritis.</p>
    Formula:C20H19FO2S
    Purezza:>99.99%
    Colore e forma:Solid
    Peso molecolare:342.43

    Ref: TM-T12862

  • COX-2-IN-21
    Targetmol
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    COX-2-IN-21

    CAS:
    <p>COX-2-IN-21 (Compound 5c) is an orally active, selective COX-2 inhibitor (IC50: 0.039 μM). COX-2-IN-21 has good anti-inflammatory potential.</p>
    Formula:C21H22N6O4
    Colore e forma:Solid
    Peso molecolare:422.44

    Ref: TM-T62259

  • APHS
    Targetmol
    + Info

    APHS

    CAS:
    <p>APHS is a cyclooxygenase-2 (COX-2) inhibitor with anti-inflammatory action. It also more potent than aspirin in the inhibition of COX-1.</p>
    Formula:C15H18O2S
    Colore e forma:Solid
    Peso molecolare:262.37

    Ref: TM-T69926