COX
Gli inibitori della cicloossigenasi (COX) sono composti che bloccano l'attività degli enzimi COX, coinvolti nella produzione di prostaglandine, mediatori chiave dell'infiammazione e del dolore. In neuroscienze, gli inibitori della COX sono studiati per il loro potenziale nel ridurre la neuroinfiammazione, implicata in varie malattie neurodegenerative come l'Alzheimer, il Parkinson e la sclerosi multipla. Inibendo la COX, questi composti possono aiutare a mitigare i processi infiammatori nel cervello e a proteggere dai danni neuronali. Presso CymitQuimica, offriamo una gamma di inibitori della COX per supportare la tua ricerca sulla neuroinfiammazione, la gestione del dolore e le malattie neurodegenerative.
Trovati 562 prodotti di "COX"
Ordinare per
Purezza (%)
0
100
|
0
|
50
|
90
|
95
|
100
(-)-Epicatechin
CAS:<p>(-)-Epicatechin (Epicatechin) is an inhibitor of cyclooxygenase-1 (COX-1), inhibiting the IL-1β-induced expression of iNOS by blocking the nuclear localization</p>Formula:C15H14O6Purezza:98.55% - 98.80%Colore e forma:SolidPeso molecolare:290.27Licofelone
CAS:<p>Licofelone (ML-3000) is a dual COX/LOX inhibitor potentially for the treatment of osteoarthritis.</p>Formula:C23H22ClNO2Purezza:99.25%Colore e forma:Yellowish SolidPeso molecolare:379.88SC-236
CAS:<p>SC-236 (Sc 236) is an orally active and selective inhibitor of COX-2 (IC50 of 0.005 μM and 17.8 μM for COX-2 and COX-1, respectively).</p>Formula:C16H11ClF3N3O2SPurezza:99.74%Colore e forma:SolidPeso molecolare:401.79Chebulagic acid
CAS:<p>Chebulagic acid, isolated from the Terminalia chebula Retz, is a COX-LOX dual inhibitor.</p>Formula:C41H30O27Purezza:97.82% - 99.8%Colore e forma:SolidPeso molecolare:954.66(-)-Epicatechin gallate
CAS:<p>(-)-Epicatechin gallate, a catechin isomer and strong antioxidant, affects membrane proteins and alters gA channel function in bilayers.</p>Formula:C22H18O10Purezza:99.16% - 99.93%Colore e forma:SolidPeso molecolare:442.37Flurbiprofen Axetil
CAS:<p>Flurbiprofen Axetil (Lipfen) is an anti-inflammatory used as an analgesic.</p>Formula:C19H19FO4Purezza:97.58% - 98%Colore e forma:SolidPeso molecolare:330.35Phenidone
CAS:<p>Phenidone inhibits COX/LOX, reducing rat autoimmune paralysis and lowering blood pressure in hypertensive rats.</p>Formula:C9H10N2OPurezza:97.24%Colore e forma:White Solid Solid CrystallinePeso molecolare:162.19Ataquimas
CAS:<p>Ataquimast inhibits IL-5 secretion along with that of TNF-a, IL-4 and GM-CSF from human cells.</p>Formula:C11H13N3OPurezza:99.96%Colore e forma:SolidPeso molecolare:203.24Neochlorogenic acid
CAS:<p>Neochlorogenic acid (trans-5-O-Caffeoylquinic acid) is an antioxidant compound used in the treatment of oxidative stress and related afflictions.</p>Formula:C16H18O9Purezza:99.12% - 99.54%Colore e forma:White PowderPeso molecolare:354.31Ibuprofen Lysine
CAS:<p>Ibuprofen Lysine (Neoprofen) is a non-steroidal anti-inflammatory drug.</p>Formula:C19H32N2O4Purezza:99.26%Colore e forma:CoaPeso molecolare:352.473-TERT-BUTYL-4-HYDROXYANISOLE
CAS:<p>3-tert-Butyl-p-hydroxyanisole is an antioxidant which is produced via water chlorination.</p>Formula:C11H16O2Purezza:99.65%Colore e forma:White Solid WaxyPeso molecolare:180.24Diclofenac Epolamine
CAS:<p>Diclofenac Epolamine (DHEP) is a non-steroidal anti-inflammatory agent (NSAID) with analgesic and antipyretic actions.</p>Formula:C20H24Cl2N2O3Purezza:99.56%Colore e forma:SolidPeso molecolare:411.32SC-560
CAS:<p>SC-560 is a member of the diaryl heterocycle class of cyclooxygenase (COX) inhibitors.</p>Formula:C17H12ClF3N2OPurezza:99.97%Colore e forma:SolidPeso molecolare:352.74Prim-O-glucosylcimifugin
CAS:<p>Prim-O-glucosylcimifugin (Cimifugin 7-glucoside) can inhibit the proliferation of SMC stimulated by TNF-alpha, increase the proportion of G0/G1 phase.</p>Formula:C22H28O11Purezza:98.57% - 99.92%Colore e forma:SolidPeso molecolare:468.45RHC 80267
CAS:<p>RHC 80267 (U-57908) is a selective inhibitor of DAGL (IC50 : 4 μM in canine platelets)</p>Formula:C20H34N4O4Purezza:99.54%Colore e forma:White SolidPeso molecolare:394.51ETHYL CAFFEATE
CAS:<p>Ethyl Caffeate (ETHYL 3,4-DIHYDROXYCINNAMATE) suppressed the differentiation of naive CD4+ T cells into Th1 in vitro.</p>Formula:C11H12O4Purezza:97.79%Colore e forma:SolidPeso molecolare:208.21Ufenamate
CAS:<p>Ufenamate (Flufenamic acid butyl ester) is an anthranilic acid-based anti-inflammatory drug developed for skin diseases</p>Formula:C18H18F3NO2Purezza:99.89%Colore e forma:SolidPeso molecolare:337.34Veratric acid
CAS:<p>Veratric acid (3,4-Dimethoxybenzoic acid) is a simple benzoic acid derived from plants and fruits with anti-oxidant, anti-inflammation and blood pressure-</p>Formula:C9H10O4Purezza:99.44%Colore e forma:SolidPeso molecolare:182.17Indomethacin farnesil
CAS:<p>Indomethacin farnesil (Infree) is a prodrug of indomethacin. It acts as a nonsteroidal anti-inflammatory drug (NSAID) and disease-modifying anti-rheumatic drug.</p>Formula:C34H40ClNO4Purezza:97.29%Colore e forma:SolidPeso molecolare:562.14N-trans-Feruloyltyramine
CAS:<p>NTF is hepatoprotective, antioxidant, inhibits COX, prevents platelet aggregation, and reduces melanin by downregulating tyrosinase.</p>Formula:C18H19NO4Purezza:99.56% - >99.99%Colore e forma:SolidPeso molecolare:313.35Phenethyl ferulate
CAS:<p>Phenethyl ferulate is a chemopreventive against colon cancer, enhancing apoptosis in tumors and inhibiting COX/5-LOX (IC50: 4.35/5.75 μM).</p>Formula:C18H18O4Purezza:99.88% - 99.91%Colore e forma:SolidPeso molecolare:298.33(S)-Flurbiprofen
CAS:<p>Esflurbiprofen is an inhibitor of COX-1 and COX-2.</p>Formula:C15H13FO2Purezza:99.99%Colore e forma:White To Yellowish Crystalline PowderPeso molecolare:244.26Dehydrodiisoeugenol
CAS:<p>Dehydrodiisoeugenol suppresses COX-2 expression and NF-κB activity, reducing inflammation in LPS-stimulated murine macrophages.</p>Formula:C20H22O4Purezza:99.97%Colore e forma:SolidPeso molecolare:326.39Ketorolac
CAS:<p>Ketorolac (Acuvail) is an NSAID that blocks prostaglandin synthesis, related to heterocyclic acetic acids.</p>Formula:C15H13NO3Purezza:99.68%Colore e forma:White Crystalline Or White PowderPeso molecolare:255.27Xanthohumol
CAS:<p>Xanthohumol, also known as 2', 4, 4'-trihydroxy-6'-methoxy-3'-prenylchalcone or desmethylxanthohumol, is a member of the class of compounds known as 3-</p>Formula:C21H22O5Purezza:98.19% - 99.67%Colore e forma:Orange PowderPeso molecolare:354.4Loxoprofen sodium (dihydrate)
CAS:<p>Loxoprofen sodium dihydrate: Non-steroidal anti-inflammatory with analgesic, antipyretic, antitumor effects; COX-1/COX-2 inhibitor. IC50: 6.5/13.5 μM.</p>Formula:C15H21NaO5Colore e forma:SolidPeso molecolare:304.318Tenidap
CAS:<p>Tenidap (CP-66248) is a selective COX-1 and SLC26A3 inhibitor with anti-inflammatory, analgesic, and anti-rheumatic activities.</p>Formula:C14H9ClN2O3SPurezza:98.56% - 99.42%Colore e forma:SolidPeso molecolare:320.75NF-κB/MAPK-IN-1
CAS:<p>NF-κB/MAPK-IN-1 is an NF-κB and MAPK pathway inhibitor. NF-κB/MAPK-IN-1 is used to prevent rheumatoid arthritis (RA).</p>Formula:C27H27NO7Purezza:97.03%Colore e forma:SolidPeso molecolare:477.51Bromfenac sodium hydrate
CAS:<p>Bromfenac sodium hydrate (Bromfenac monosodium salt sesquihydrate) is the sodium salt form of bromfenac, a NSAID with analgesic and anti-inflammatory effects.</p>Formula:C15H12BrNO3H2O·NaPurezza:91.85% - 99.65%Colore e forma:SolidPeso molecolare:383.17Oxyphenbutazone
CAS:<p>Oxyphenbutazone: Non-selective COX inhibitor, anti-inflammatory, kills dormant Mycobacterium tuberculosis.</p>Formula:C19H20N2O3Purezza:99.41% - 99.88%Colore e forma:White To Yellowish White Crystalline Powder SolidPeso molecolare:324.37Meloxicam
CAS:<p>Meloxicam (Metacam) is a Nonsteroidal Anti-inflammatory Drug.</p>Formula:C14H13N3O4S2Purezza:97.09% - 99.60%Colore e forma:Light Yellow SolidPeso molecolare:351.40Fenoprofen
CAS:<p>Fenoprofen (LILLY-5385) is a non-steroidal anti-inflammatory compound and a modifier enhancer of the melanocortin receptor, increasing ERK1/2 activation.</p>Formula:C15H14O3Purezza:98.4%Colore e forma:SolidPeso molecolare:242.27(S)-(+)-Ibuprofen
CAS:<p>(S)-(+)-Ibuprofen (Dexibuprofen) , is a non-steroidal anti-inflammatory drug (NSAID), inhibiting cyclooxygenase (COX).</p>Formula:C13H18O2Purezza:99.51% - 99.86%Colore e forma:Colourless Crystalline SolidPeso molecolare:206.28Paradol
CAS:<p>Paradol, a spicy compound in ginger, offers anti-cancer, anti-inflammatory, antioxidant, and neuroprotective benefits.</p>Formula:C17H26O3Purezza:98.4% - 98.98%Colore e forma:SolidPeso molecolare:278.39Fontolizumab
CAS:<p>Fontolizumab (HuZAF) is a humanised IgG1 monoclonal anti-IFN-gamma (IFN-γ) antibody for the study of Crohn's disease.</p>Purezza:95%Colore e forma:LiquidPeso molecolare:150 (kDa)Aspirin DL-lysine
CAS:<p>Aspirin DL-lysine: a water-soluble, injectable NSAID that may also hinder cancer growth.</p>Formula:C15H22N2O6Colore e forma:Crystalline SolidPeso molecolare:326.35Cadonilimab
CAS:<p>Cadonilimab (AK104) is a tetravalent PD-1/CTLA-4 bispecific humanised antibody that activates T cells by enhancing IL-2 and IFN-γ secretion.</p>Purezza:95% - 95%Colore e forma:LiquidImidazole Salicylate
CAS:<p>Imidazole Salicylate, a non-steroidal anti-inflammatory drug, has limited inhibitory effects on prostaglandin synthesis.</p>Formula:C10H10N2O3Purezza:98%Colore e forma:SolidPeso molecolare:206.2Indometacin Farnesil
CAS:Formula:C34H40ClNO4Purezza:>98.0%(HPLC)Colore e forma:Light yellow to Yellow to Orange clear liquidPeso molecolare:562.15Ketorolac-d5
CAS:<p>Ketorolac-d5 is a deuterated compound of ketorolac for isotope tracing. Ketorolac is a non-steroidal anti-inflammatory agent and inhibitor of COX-1 and COX-2.</p>Formula:C15H8D5NO3Purezza:98.99%Colore e forma:SolidPeso molecolare:260.3Nepafenac-d5
CAS:<p>Nepafenac D5 is the deuterium labeled Nepafenac, which is a selective inhibitor of COX-2 .</p>Formula:C15H14N2O2Purezza:98%Colore e forma:SolidPeso molecolare:259.31AHR-10037
CAS:<p>AHR-10037, a NSAID, offers pain relief, fever reduction, safety, and low stomach risk, acting as a prodrug for COX inhibitors.</p>Formula:C15H13ClN2O2Purezza:98%Colore e forma:SolidPeso molecolare:288.73Amfenac
CAS:<p>Amfenac promotes apoptosis in ARPE-19 cell culture.</p>Formula:C15H13NO3Colore e forma:SolidPeso molecolare:255.27Pelubiprofen
CAS:<p>Pelubiprofen is a non-steroidal anti-inflammatory agent and a COX-2 inhibitor, which effectively reduces PGE(2) production by inhibiting COX activity.</p>Formula:C16H18O3Purezza:99.69%Colore e forma:SolidPeso molecolare:258.31COX-2-IN-2
CAS:<p>COX-2-IN-2 selectively inhibits COX2 (IC50: 0.24 μM); COX-2-IN-1 offers anti-inflammatory and pain relief.</p>Formula:C17H12FN3O2SPurezza:97.62%Colore e forma:SolidPeso molecolare:341.36COX-2-IN-26
CAS:<p>COX-2-IN-26: Oral, selective COX-2 inhibitor, low IC50s; anti-inflammatory with GI safety.</p>Formula:C23H21N7OS3Colore e forma:SolidPeso molecolare:507.65Loxoprofenol-SRS tromethamine
CAS:<p>Loxoprofenol-SRS tromethamine (HR1405-01), a metabolite of Loxoprofen, is a safe IV NSAID with strong anti-inflammatory and pain relief properties.</p>Formula:C19H31NO6Colore e forma:SolidPeso molecolare:369.45COX-2-IN-24
CAS:<p>COX-2-IN-24 is an orally active COX-2 inhibitor (IC50: 0.17 μM) with anti-inflammatory and hypo-ulcerogenic effects.</p>Formula:C24H24BrN5O3S2Colore e forma:SolidPeso molecolare:574.51COX-2-IN-18
CAS:<p>COX-2-IN-18 is a potent COX-2 inhibitor similar to Celecoxib, showing promise in cancer research. IC50=0.775μM.</p>Formula:C18H19N3O3S2Colore e forma:SolidPeso molecolare:389.49COX-2-IN-14
CAS:<p>COX-2-IN-14 (2a) is a potent, selective COX-2 inhibitor with high affinity and notable anti-inflammatory effects in mice.</p>Formula:C18H18N4O6Colore e forma:SolidPeso molecolare:386.364
