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COX

COX

Gli inibitori della cicloossigenasi (COX) sono composti che bloccano l'attività degli enzimi COX, coinvolti nella produzione di prostaglandine, mediatori chiave dell'infiammazione e del dolore. In neuroscienze, gli inibitori della COX sono studiati per il loro potenziale nel ridurre la neuroinfiammazione, implicata in varie malattie neurodegenerative come l'Alzheimer, il Parkinson e la sclerosi multipla. Inibendo la COX, questi composti possono aiutare a mitigare i processi infiammatori nel cervello e a proteggere dai danni neuronali. Presso CymitQuimica, offriamo una gamma di inibitori della COX per supportare la tua ricerca sulla neuroinfiammazione, la gestione del dolore e le malattie neurodegenerative.

Trovati 562 prodotti di "COX"

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  • Safrole oxide
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    Safrole oxide

    CAS:
    <p>Safrole oxide inhibits neuronal growth, induces apoptosis, elevates COX-2, IL-8, ROS, promoting endothelial-to-neuron-like cell transdifferentiation.</p>
    Formula:C10H10O3
    Purezza:100%
    Colore e forma:Solid
    Peso molecolare:178.18

    Ref: TM-T34627

  • (-)-Ibuprofenamide
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    (-)-Ibuprofenamide

    CAS:
    <p>(-)-Ibuprofenamide is an amide prodrug of Ibuprofen with anti-inflammatory activity.</p>
    Formula:C13H19NO
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:205.3

    Ref: TM-T11605

  • Piroxicam cinnamate
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    Piroxicam cinnamate

    CAS:
    <p>Cinnoxicam is a COX inhibitor used for bone/joint inflammation, rheumatic issues, and varicocele-related oligospermia.</p>
    Formula:C24H19N3O5S
    Colore e forma:Solid
    Peso molecolare:461.49

    Ref: TM-T62913

  • GW-406381
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    GW-406381

    CAS:
    <p>GW-406381 is a highly selective COX-2 inhibitor peripherally and centrally, reducing spontaneous ectopic discharges following chronic compressive injury.</p>
    Formula:C21H19N3O3S
    Purezza:99.54%
    Colore e forma:Solid
    Peso molecolare:393.46

    Ref: TM-T15449

  • COX-2/5-LOX-IN-2
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    COX-2/5-LOX-IN-2

    CAS:
    <p>COX-2/5-LOX-IN-2, a benzothiophen derivative, inhibits COX-1, COX-2, 5-LOX with IC50s of 5.40, 0.01, 1.78 μM. More effective than Celecoxib, Indomethacin.</p>
    Formula:C18H13N3O4S2
    Colore e forma:Solid
    Peso molecolare:399.44

    Ref: TM-T61910

  • COX-2-IN-19
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    COX-2-IN-19

    CAS:
    <p>COX-2-IN-19, a potent COX-2 inhibitor, IC50 of 1.76 μM, has strong anti-inflammatory effects in vivo.</p>
    Formula:C18H18N4O2S
    Colore e forma:Solid
    Peso molecolare:354.43

    Ref: TM-T61264

  • Timegadine
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    Timegadine

    CAS:
    <p>Timegadine is a competitive inhibitor of COX and lipo-oxygenase, with IC50s ranging from 5 nM (washed rabbit platelets) to 20 μM (rat brain) for COX and 100 μM</p>
    Formula:C20H23N5S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:365.5

    Ref: TM-T13160

  • ADU-S100
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    ADU-S100

    CAS:
    <p>ADU-S100 (MIW815) is a STING agonist that significantly induces the production of IFN-β,TNF-α,IL-6,and MCP-1,induces TBK1 and IRF3 phosphorylation,antitumour.</p>
    Formula:C20H24N10O10P2S2
    Purezza:99.83%
    Colore e forma:Solid
    Peso molecolare:690.54

    Ref: TM-T10252L3

  • COX-2/5-LOX-IN-1
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    COX-2/5-LOX-IN-1

    CAS:
    <p>COX-2/5-LOX-IN-1, a benzothiophen-2-yl pyrazole, inhibits COX-2 &amp; 5-LOX with IC50: COX-1 (12.13μM), COX-2 (0.4μM), 5-LOX (4.96μM). Better than Celecoxib.</p>
    Formula:C14H10ClN3O4S2
    Colore e forma:Solid
    Peso molecolare:383.83

    Ref: TM-T61674

  • Heterophdoid A
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    Heterophdoid A

    CAS:
    <p>Heterophdoid A is an anti-inflammatory agent that inhibits NO production in BV-2 cells (IC50: 5.93 μM).</p>
    Formula:C26H42O10
    Colore e forma:Solid
    Peso molecolare:514.61

    Ref: TM-T63570

  • Naproxcinod
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    Naproxcinod

    CAS:
    <p>Naproxcinod is a derivative of naproxen, analgesic and anti-inflammatory, a COX-inhibitory nitric oxide donor (CINOD), osteoarthritis and inflammatory.</p>
    Formula:C18H21NO6
    Colore e forma:Solid
    Peso molecolare:347.36

    Ref: TM-T33595

  • Nitroflurbiprofen
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    Nitroflurbiprofen

    CAS:
    <p>Nitroflurbiprofen (Nitroxybutyl flurbiprofen) is a NO-releasing COX inhibitor and modulates the increased intrahepatic vascular tone in portal hypertensive</p>
    Formula:C19H20FNO5
    Purezza:99.88%
    Colore e forma:Solid
    Peso molecolare:361.36

    Ref: TM-T16329

  • COX-2-IN-28
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    COX-2-IN-28

    CAS:
    <p>COX-2-IN-28 is a potent and selective COX-2 inhibitor capable of acting on COX-2 (IC50: 0.054 μM), 15-LOX (IC50: 2.14 μM) and COX-1 (IC50: 13.21 μM).</p>
    Formula:C30H27N7S3
    Colore e forma:Solid
    Peso molecolare:581.78

    Ref: TM-T64109

  • COX-2-IN-11
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    COX-2-IN-11

    CAS:
    <p>COX-2-IN-11 (compound 7b2) is a potent and selective COX-2 inhibitor. COX-2-IN-11 has the potential in inflammation disease research[1].</p>
    Formula:C12H12OS3
    Colore e forma:Solid
    Peso molecolare:268.42

    Ref: TM-T60457

  • Naproxen etemesil
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    Naproxen etemesil

    CAS:
    <p>Naproxen, a COX-1/2 inhibitor, has IC50s of 8.72/5.15 μM. Its prodrug, naproxen etemesil, is lipophilic and converts to active form upon absorption.</p>
    Formula:C17H20O5S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:336.4

    Ref: TM-T16272

  • Apyramide
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    Apyramide

    CAS:
    <p>Apyramide, an NSAID and prodrug of indomethacin, inhibits COX1/COX2 and permeates the blood-brain barrier.</p>
    Formula:C27H23ClN2O5
    Purezza:99.93%
    Colore e forma:Solid
    Peso molecolare:490.93

    Ref: TM-T10355

  • ABT-963
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    ABT-963

    CAS:
    <p>ABT-963: COX-2 inhibitor for osteoarthritis/pain with high selectivity, potency, and gastric safety.</p>
    Formula:C22H22F2N2O5S
    Purezza:98% - 99.85%
    Colore e forma:Solid
    Peso molecolare:464.48

    Ref: TM-T26531

  • ER-34122
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    ER-34122

    CAS:
    <p>ER-34122, a novel orally available dual 5-lipoxygenase/cyclooxygenase inhibitor with potent anti-inflammatory activity.</p>
    Formula:C27H26ClN3O5
    Purezza:>99.99%
    Colore e forma:Solid
    Peso molecolare:507.96

    Ref: TM-T70188

  • Eltenac
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    Eltenac

    CAS:
    <p>Eltenac, a cyclooxygenase (COX) inhibitor, is used potentially for the treatment of pain.</p>
    Formula:C12H9Cl2NO2S
    Purezza:98.53%
    Colore e forma:Solid
    Peso molecolare:302.18

    Ref: TM-T27254

  • Sudoxicam
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    Sudoxicam

    CAS:
    <p>Sudoxicam (4-Hydroxy-2-methyl-N-2-thiazolyl-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide) is a reversible antagonist of COX with anti-inflammatory, anti-edema</p>
    Formula:C13H11N3O4S2
    Purezza:99.93%
    Colore e forma:Solid
    Peso molecolare:337.37

    Ref: TM-T16950