CaMK
Gli inibitori della Protein-Chinasi Dipendente dal Calcio/Calmodulina (CaMK) sono composti specializzati che inibiscono l'attività della CaMK, una chinasi critica coinvolta in una varietà di processi cellulari, in particolare nel sistema nervoso. La CaMK è essenziale per tradurre i segnali di calcio in varie risposte cellulari, tra cui la plasticità sinaptica, la formazione della memoria e l'espressione genica. La disregolazione dell'attività della CaMK è associata a numerosi disturbi neurologici, rendendo questi inibitori strumenti preziosi per lo studio della segnalazione sinaptica, dell'apprendimento e della memoria. Presso CymitQuimica, offriamo inibitori della CaMK di alta qualità per supportare la tua ricerca sulla plasticità sinaptica, la funzione cognitiva e la neurofarmacologia.
Trovati 73 prodotti di "CaMK"
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Trifluoperazine dihydrochloride
CAS:Trifluoperazine dihydrochloride (SKF5019) is a potent dopamine D2 receptor inhibitor used as an antipsychotic and an antiemetic.Formula:C21H26Cl2F3N3SPurezza:99.57% - 99.96%Colore e forma:Cream Fine PowderPeso molecolare:480.43Y-33075 dihydrochloride
CAS:Y-33075 dihydrochloride is a selective inhibitor of ROCK(IC50 of 3.6 nM).Formula:C16H18Cl2N4OPurezza:98.88% - 99.89%Colore e forma:SolidPeso molecolare:353.25Ref: TM-T13384L
1mg35,00€5mg70,00€10mg107,00€25mg202,00€50mg360,00€100mg538,00€200mg772,00€1mL*10mM (DMSO)82,00€A-3 hydrochloride
CAS:A-3 hydrochloride: potent, reversible kinase antagonist; permeable; inhibits PKC, CKI, PKA, CKII, MLCK; Ki: 4.3-80 μM.
Formula:C12H14Cl2N2O2SPurezza:99.32%Colore e forma:SolidPeso molecolare:321.22Elziverine
CAS:Elziverine: oral calmodulin antagonist, inhibits Ca-induced acanthocyte formation, potential for neurological and cognitive disorder treatment.
Formula:C32H37N3O5Purezza:99.79%Colore e forma:SolidPeso molecolare:543.65Fasciculic acid A
CAS:Fasciculic acid A is a calmodulin antagonist isolated from mushroom Naematoloma fasciculare.Formula:C36H60O8Colore e forma:SolidPeso molecolare:620.868TAT-CN21 (scrambled)
TAT-CN21(scrambled) is a control peptide lacking specific targeting activity and serves as a negative control for TatCN21. TatCN21 is an effective and selective inhibitory peptide for calcium/calmodulin-dependent protein kinase II (CaMKII).Colore e forma:Odour SolidFasciculic acid B
CAS:Fasciculic acid B: ester of fasciculol B, 3-hydroxy-methylglutaric acid; a calmodulin antagonist from Naematoloma fasciculare.Formula:C36H60O9Purezza:98%Colore e forma:SolidPeso molecolare:636.86Encecalinol
CAS:Encecalinol, a compound isolated from the aerial parts of Ageratina grandifolia, acts as a potent inhibitor of calmodulin [1].Formula:C14H18O3Colore e forma:SolidPeso molecolare:234.29CALP2 TFA
CALP2 TFA, a CaM antagonist with 7.9 µM Kd, blocks CaM-dependent enzymes, boosts Ca2+ levels, and activates macrophages.Formula:C70H105F3N14O15SColore e forma:SolidPeso molecolare:1471.72Calmodulin-Dependent Protein Kinase II 290-309 acetate
Calmodulin-Dependent Protein Kinase II 290-309 acetate is an effective antagonist of Ca2+/calmodulin-dependent protein kinase II (IC50 = 52 nM).Formula:C105H189N31O26SPurezza:96.7%Colore e forma:SolidPeso molecolare:2333.88Cloxacepride
CAS:cloxacepride is a CaM antagonist that is used to treat asthma disease.Formula:C22H27Cl2N3O4Purezza:99.76%Colore e forma:SolidPeso molecolare:468.37Beauverolide Ja
CAS:Beauverolide Ja: cyclotetradepsipeptide, CaM inhibitor; Kd 0.078 μM, Ki 0.39 μM; from Isaria fumosorosea.Formula:C35H46N4O5Colore e forma:SolidPeso molecolare:602.76CALP2
CAS:CALP2 is a CaM antagonist blocking EF-hand/Ca2+ site; inhibits CaM phosphodiesterase, raises Ca2+, and activates alveolar macrophages.Formula:C68H104N14O13SPurezza:98%Colore e forma:SolidPeso molecolare:1357.72Calmodulin-Dependent Protein Kinase II (281-309)
CAS:Calmodulin-Dependent Protein Kinase II (281-309) is a synthetic peptide that can be phosphorylated at Thr286 by PKC and inhibits CaM kinase II (IC50 = 80 nM).Formula:C146H254N46O39S3Purezza:98%Colore e forma:SolidPeso molecolare:3374.06TAT-CN21
TatCN21, with an IC 50 of 77 nM, serves as a potent and selective inhibitor peptide of the calcium/calmodulin-dependent protein kinase II (CaMKII), a ubiquitously-expressed multifunctional serine/threonine protein kinase. It is particularly useful in research pertaining to ischemia and neurodegenerative diseases.Formula:C169H303N69O43Colore e forma:SolidPeso molecolare:3989.65Calmodulin Binding Peptide 1
CAS:Calmodulin Binding Peptide 1, a high-affinity MLCK-derived inhibitor, blocks IP3-induced Ca2+ release.Formula:C231H373N69O70S2Purezza:98%Colore e forma:SolidPeso molecolare:5301.1Acremonidin A
CAS:Acremonidin A, from Purpureocillium lilacinum, is a strong CaM inhibitor binding to hCaM M124C-mBBr with a Kd of 19.40 nM.Formula:C33H26O12Colore e forma:SolidPeso molecolare:614.55Fasciculic acid C
CAS:Fasciculic acid C is a calmodulin antagonist isolated from mushroom Naematoloma fasciculare.Formula:C38H63NO11Purezza:98%Colore e forma:SolidPeso molecolare:709.91RA306
RA306 is an orally active CAMK2 inhibitor that effectively disrupts the PEAK1/CAMK2 signaling pathway. It demonstrates anti-tumor activity by inhibiting proliferation, migration, and invasion of breast cancer cells. Additionally, RA306 shows potential in cardiac disease research, as it improves dilated cardiomyopathy in mice.Colore e forma:Odour SolidFluphenazine-N-2-chloroethane (hydrochloride)
CAS:Fluphenazine: antipsychotic, binds dopamine D2 (Ki=0.55nM), inhibits calmodulin. Its derivative adds irreversible D2 antagonism and anticancer potential.Formula:C22H27Cl3F3N3SColore e forma:SolidPeso molecolare:528.89
