CaMK
Gli inibitori della Protein-Chinasi Dipendente dal Calcio/Calmodulina (CaMK) sono composti specializzati che inibiscono l'attività della CaMK, una chinasi critica coinvolta in una varietà di processi cellulari, in particolare nel sistema nervoso. La CaMK è essenziale per tradurre i segnali di calcio in varie risposte cellulari, tra cui la plasticità sinaptica, la formazione della memoria e l'espressione genica. La disregolazione dell'attività della CaMK è associata a numerosi disturbi neurologici, rendendo questi inibitori strumenti preziosi per lo studio della segnalazione sinaptica, dell'apprendimento e della memoria. Presso CymitQuimica, offriamo inibitori della CaMK di alta qualità per supportare la tua ricerca sulla plasticità sinaptica, la funzione cognitiva e la neurofarmacologia.
Trovati 72 prodotti di "CaMK"
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Fasciculic acid B
CAS:Fasciculic acid B: ester of fasciculol B, 3-hydroxy-methylglutaric acid; a calmodulin antagonist from Naematoloma fasciculare.Formula:C36H60O9Purezza:98%Colore e forma:SolidPeso molecolare:636.86Calmodulin-Dependent Protein Kinase II 290-309 acetate
Calmodulin-Dependent Protein Kinase II 290-309 acetate is an effective antagonist of Ca2+/calmodulin-dependent protein kinase II (IC50 = 52 nM).Formula:C105H189N31O26SPurezza:96.7%Colore e forma:SolidPeso molecolare:2333.88CALP2 TFA
CALP2 TFA, a CaM antagonist with 7.9 µM Kd, blocks CaM-dependent enzymes, boosts Ca2+ levels, and activates macrophages.Formula:C70H105F3N14O15SColore e forma:SolidPeso molecolare:1471.72Purine riboside triphosphate
CAS:Purine riboside triphosphate resembles adenosine; inhibits cancer cell growth by blocking RNA/DNA synthesis.Formula:C10H15N4O13P3Colore e forma:SolidPeso molecolare:492.17Purine riboside-5'-O-triphosphate sodium
CAS:Purine riboside-5'-O-triphosphate sodium is an active metabolite of Nebularine (HY-103694) and acts as an inhibitor of DNA primase ATP and GTP polymerization activities, with IC50 values of 35 µM and 28 µM, respectively. It also inhibits calmodulin-dependent protein kinase II (CaMKII), with a Ki value of 590 µM.Formula:C10H11N4Na4O13P3Peso molecolare:580.09Syntide 2 TFA
Syntide 2 (TFA) is a CaMKII substrate that selectively hinders GA response without affecting other plant processes.Formula:C70H123N20F3O20Colore e forma:SolidPeso molecolare:1621.84CAMKIV Protein, Human, Recombinant (GST)
CAMKIV Protein, Human, Recombinant (GST) is expressed in Baculovirus insect cells with GST tag.Colore e forma:Lyophilized PowderPeso molecolare:79 kDa (predicted); 100 kDa (reducing conditions)KN-62
CAS:KN-62 is a potent and specific Ca2+/calmodulin-dependent protein kinase II (CaMKII) inhibitor with Ki of 0.9 μM.Formula:C38H35N5O6S2Purezza:99.80% - >99.99%Colore e forma:White SolidPeso molecolare:721.84Ref: TM-T2694
1mg35,00€2mg52,00€5mg74,00€10mg111,00€25mg217,00€50mg425,00€100mg625,00€1mL*10mM (DMSO)111,00€CALP2 acetate(261969-04-4 free base)
CALP2 acetate is an antagonist of calmodulin showing high affinity for binding to the CaM EF-hand/Ca2+-binding site with a Kd of 7.9 µM.Formula:C68H104N14O13SPurezza:97.43%Colore e forma:SolidPeso molecolare:1357.7Syntide 2 acetate(108334-68-5 free base)
Syntide-2 acetate is a synthetic peptide recognized as a substrate by Ca2+/calmodulin-dependent protein kinase II (CaMKII; Km = 12 μM).Formula:C70H126N20O20Purezza:99.74%Colore e forma:SolidPeso molecolare:1567.85Autocamtide-2-related inhibitory peptide
CAS:Autocamtide-2-related inhibitory peptide is a highly specific and potent inhibitor of CaMKII with an IC50 of 40 nM.Formula:C64H116N22O19Purezza:>99.99%Colore e forma:SolidPeso molecolare:1497.74Autocamtide 2 TFA(129198-88-5 free base)
<p>Autocamtide 2 TFA, selective CaMKII peptide substrate, used in its activity assay.</p>Formula:C67H119F3N22O22Purezza:98%Colore e forma:SolidPeso molecolare:1641.79CaMKP Inhibitor
CAS:<p>CaMKP Inhibitor can inhibit CaMKP.</p>Formula:C10H8NNaO7S2Purezza:96.55% - 99.98%Colore e forma:SolidPeso molecolare:341.28GSK3i XIII
CAS:GSK3i XIII (GSK3 inhibitor XIII) is a GSK-3 ATP-binding site inhibitor.Formula:C18H19N5Purezza:98.87%Colore e forma:SolidPeso molecolare:305.38Ref: TM-T24111
1mg66,00€5mg120,00€10mg175,00€25mg295,00€50mg429,00€100mg605,00€1mL*10mM (DMSO)135,00€IGS-1.76
CAS:IGS-1.76 binds strongly to hNCS-1, modulates its Ric8a interaction, and inhibits the hNCS-1/Ric8a complex.Formula:C22H18N2OSPurezza:98.18% - 98.56%Colore e forma:SolidPeso molecolare:358.46Ref: TM-T8784
1mg42,00€5mg88,00€10mg125,00€25mg216,00€50mg305,00€100mg425,00€200mg580,00€1mL*10mM (DMSO)87,00€KN-92
CAS:KN-92 is an inactive analog of the CaM kinase II inhibitor KN 93.Formula:C24H25ClN2O3SColore e forma:SolidPeso molecolare:456.98KN-93
CAS:KN-93 is a selective inhibitor of Ca2+/calmodulin-dependent kinase II (CaMKII), competitively blocking CaM binding to the kinase.Formula:C26H29ClN2O4SPurezza:99.56% - 99.86%Colore e forma:White SolidPeso molecolare:501.04Ref: TM-T2697
1mg57,00€2mg79,00€5mg113,00€10mg155,00€25mg305,00€50mg378,00€100mg552,00€1mL*10mM (DMSO)127,00€Trifluoperazine
CAS:Trifluoperazine (trifluoroperazine) is a Dopamine D2 receptor inhibitor(IC50 : 1.2 nM), and Treatment of schizophrenia.Formula:C21H24F3N3SPurezza:98.3% - 99.46%Colore e forma:White To Yellowish Crystalline PowderPeso molecolare:407.5NH125
CAS:NH125 is a selective eEF-2 kinase inhibitor with IC50 of 60 nM, >125-fold selectivity over PKC, PKA, and CaMKII, and also a potent histidine kinase inhibitor.Formula:C27H45IN2Purezza:98.60%Colore e forma:SolidPeso molecolare:524.56Ref: TM-T6605
1mg40,00€2mg52,00€5mg88,00€10mg119,00€25mg264,00€50mg454,00€100mg655,00€1mL*10mM (DMSO)87,00€CALP1 acetate
<p>CALP1 acetate is a calmodulin (CaM) agonist (Kd of 88 µM) that binds to the CaM EF-hand/Ca2+-binding site.</p>Formula:C42H79N9O12Purezza:99.63%Colore e forma:SolidPeso molecolare:902.13
