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GluR

GluR

Gli inibitori dei recettori del glutammato sono composti che bloccano l'attività dei recettori del glutammato, i principali recettori dei neurotrasmettitori eccitatori nel cervello. Questi recettori svolgono un ruolo cruciale nella trasmissione sinaptica, nella plasticità, nell'apprendimento e nella memoria. La disregolazione della segnalazione del glutammato è associata a vari disturbi neurologici, come l'epilessia, l'ictus e le malattie neurodegenerative. Gli inibitori dei recettori del glutammato sono essenziali per studiare i meccanismi dell'eccitotossicità e sviluppare strategie neuroprotettive. Presso CymitQuimica, offriamo una gamma di inibitori dei recettori del glutammato per supportare la vostra ricerca sulla funzione sinaptica, la neuroprotezione e i disturbi cognitivi.

Trovati 263 prodotti di "GluR"

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  • Basimglurant

    CAS:
    <p>Basimglurant (CTEP Derivative) is a potent, selective and orally available modulator of mGlu5 negative allosteric(Kd of 1.1 nM).</p>
    Formula:C18H13ClFN3
    Purezza:98.35%
    Colore e forma:Solid
    Peso molecolare:325.77

    Ref: TM-T12717

    1mg
    74,00€
    5mg
    160,00€
    10mg
    235,00€
    25mg
    378,00€
    50mg
    562,00€
    100mg
    702,00€
    200mg
    949,00€
    1mL*10mM (DMSO)
    170,00€
  • Decoglurant

    CAS:
    <p>Decoglurant (RO4995819) is a negative allosteric modulator of mGluR2 and mGluR3 and it also is developed as an antidepressant.</p>
    Formula:C21H11F6N5
    Purezza:99.77%
    Colore e forma:Solid
    Peso molecolare:447.34

    Ref: TM-T15090

    1mg
    55,00€
    5mg
    117,00€
    10mg
    167,00€
    25mg
    309,00€
    50mg
    434,00€
    100mg
    605,00€
    200mg
    815,00€
  • VU0650786

    CAS:
    VU0650786: selective mGlu3 NAM, CNS-penetrant, IC50 392 nM, shows antidepressant/anxiolytic effects in rodents.
    Formula:C18H15ClFN5O2
    Purezza:99.09%
    Colore e forma:Solid
    Peso molecolare:387.8

    Ref: TM-T13318

    1mg
    96,00€
    5mg
    235,00€
    10mg
    329,00€
    25mg
    560,00€
    50mg
    800,00€
    100mg
    1.103,00€
    1mL*10mM (DMSO)
    259,00€
  • DHPG

    CAS:
    DHPG is a potent Group I mGluR agonist; doesn't affect Group II/III; linked to phospholipase D.
    Formula:C8H9NO4
    Purezza:99.55%
    Colore e forma:Solid
    Peso molecolare:183.16

    Ref: TM-T11032

    5mg
    50,00€
    10mg
    74,00€
    25mg
    125,00€
    50mg
    220,00€
  • Org-26576

    CAS:
    Org-26576 is a positive allosteric modulator of the AMPA receptor.
    Formula:C11H12N2O2
    Purezza:99.67%
    Colore e forma:Solid
    Peso molecolare:204.23

    Ref: TM-T16402

    5mg
    47,00€
    10mg
    70,00€
    25mg
    104,00€
    50mg
    150,00€
    100mg
    256,00€
    200mg
    379,00€
    1mL*10mM (DMSO)
    50,00€
  • LY339434 HCl


    LY339434 HCl is a low affinity GluR5 erythrocyte receptor agonist.LY339434 HCl causes rapid neuronal death primarily by affecting N-methyl-D-aspartate (NMDA)
    Formula:C18H20ClNO4
    Purezza:97.10% - 97.19%
    Colore e forma:Soild
    Peso molecolare:349.81

    Ref: TM-T27947L

    1mg
    185,00€
    5mg
    409,00€
    10mg
    605,00€
    25mg
    938,00€
    50mg
    1.293,00€
    100mg
    1.738,00€
    500mg
    3.496,00€
  • Piracetam

    CAS:
    Piracetam (UCB-6215), a cyclic derivative of the neurotransmitter gamma-aminobutyric acid (GABA), is used in therapy of the extensive cognitive disorders.
    Formula:C6H10N2O2
    Purezza:97.16%
    Colore e forma:Crystals From Isopropanol Solid
    Peso molecolare:142.16

    Ref: TM-T0426

    1g
    35,00€
    1mL*10mM (DMSO)
    55,00€
  • γ-DGG acetate(6729-55-1 free base)

    CAS:
    gamma-DGG acetate(6729-55-1 free base) (γ-D-Glutamylglycine) is a competitive blocker of AMPA receptor.
    Formula:C9H16N2O7
    Purezza:99.81%
    Colore e forma:Solid
    Peso molecolare:264.23

    Ref: TM-T15369L

    25mg
    47,00€
    50mg
    52,00€
  • (R)-ADX-47273

    CAS:
    <p>(R)-ADX-47273 is a potent mGluR5 positive allosteric modulator(EC50 of 168 nM for potentiation ).</p>
    Formula:C20H17F2N3O2
    Purezza:99.87%
    Colore e forma:Solid
    Peso molecolare:369.36

    Ref: TM-T13441

    2mg
    42,00€
    5mg
    65,00€
    10mg
    94,00€
    25mg
    170,00€
    50mg
    259,00€
    100mg
    391,00€
    200mg
    545,00€
  • (R)-3,4-DCPG HCl


    <p>(R)-3,4-DCPG HCl is a potent and selective mGlu8a receptor agonist that activates metabotropic glutamate receptors on primary afferent terminals in the neonatal</p>
    Formula:C10H10ClNO6
    Purezza:98.80% - 99.89%
    Colore e forma:Soild
    Peso molecolare:275.64

    Ref: TM-T23215L

    1mg
    115,00€
    5mg
    250,00€
    10mg
    369,00€
    25mg
    562,00€
  • AZD-8529 mesylate

    CAS:
    AZD-8529 mesylate is a highly selective, and orally bioavailable positive allosteric modulator of mGluR2 (EC50: 285 nM).
    Formula:C25H28F3N5O6S
    Purezza:99.19%
    Colore e forma:Solid
    Peso molecolare:583.58

    Ref: TM-T10432L

    1mg
    57,00€
    5mg
    120,00€
    10mg
    188,00€
    25mg
    432,00€
    50mg
    747,00€
    100mg
    1.093,00€
    200mg
    1.454,00€
    1mL*10mM (DMSO)
    156,00€
  • KM02894

    CAS:
    KM02894 inhibits glutamate release, potentially reducing cancer-induced bone pain in tumor studies.
    Formula:C7H9N3OS2
    Purezza:99.98%
    Colore e forma:Solid
    Peso molecolare:215.3

    Ref: TM-T77581

    25mg
    34,00€
  • NBQX disodium

    CAS:
    NBQX Disodium (FG9202 disodium) is a highly selective, competitive AMPA receptor antagonist with neuroprotective and anticonvulsant activity.
    Formula:C12H6N4Na2O6S
    Purezza:97.32% - 97.6%
    Colore e forma:Solid
    Peso molecolare:380.2415

    Ref: TM-T25853

    1mg
    42,00€
    5mg
    88,00€
    10mg
    120,00€
    25mg
    235,00€
    50mg
    354,00€
    100mg
    530,00€
    1mL*10mM (DMSO)
    96,00€
  • LY3027788

    CAS:
    LY3027788, potent oral prodrug of LY3020371, is a strong mGlu2/3 antagonist with notable antidepressant effects.
    Formula:C25H31F2NO11S
    Colore e forma:Solid
    Peso molecolare:591.58

    Ref: TM-T38792

    5mg
    922,00€
  • LY3027788 hydrochloride

    CAS:
    LY3027788 HCl, potent oral prodrug of LY3020371, targets mGlu2/3 with antidepressant effects.
    Formula:C25H32ClF2NO11S
    Colore e forma:Solid
    Peso molecolare:628.03

    Ref: TM-T38790

    5mg
    922,00€
  • LY2812223

    CAS:
    LY2812223: selective mGlu2 agonist; binds mGlu2/mGlu3 (Ki=144/156 nM).
    Formula:C10H12N4O4S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:284.29

    Ref: TM-T15809

    25mg
    Prezzo su richiesta
    50mg
    Prezzo su richiesta
    100mg
    Prezzo su richiesta
  • ML353


    ML353 activates TREK-1/2, binds mGlu5 SAM (Ki=18.2 nM), surpasses 5mpep, may address SAM activity/blocking.
    Formula:C19H15FN2O
    Purezza:99.98% - 99.98%
    Colore e forma:Soild
    Peso molecolare:306.33

    Ref: TM-T67917

    5mg
    49,00€
    10mg
    79,00€
    25mg
    120,00€
    50mg
    164,00€
    100mg
    230,00€
    200mg
    314,00€
    1mL*10mM (DMSO)
    52,00€
  • GYKI-47261 dihydrochloride

    CAS:
    <p>GYKI-47261 dihydrochloride is an AMPA receptor antagonist and CYP2E1 inducer, demonstrating broad-spectrum anticonvulsant and neuroprotective activities.</p>
    Formula:C18H17Cl3N4
    Purezza:98.32% - 99.14%
    Colore e forma:Solid
    Peso molecolare:395.71

    Ref: TM-T38601

    1mg
    302,00€
    5mg
    727,00€
    10mg
    999,00€
    25mg
    1.539,00€
  • mGluR5 modulator 1

    CAS:
    mGluR5 modulator 1 is a positive modulator for mGluR5, used in schizophrenia and cognitive research.
    Formula:C18H19ClFN3O2
    Colore e forma:Solid
    Peso molecolare:363.82

    Ref: TM-T38659

    5mg
    922,00€
  • JF-NP-26


    Releases pain-blocking raseglurant under 405 nm light. Inhibits Quisqualate. Analgesic in vivo. Quantum yield: 0.18.
    Colore e forma:Solid

    Ref: TM-T38229

    5mg
    379,00€