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GluR

GluR

Gli inibitori dei recettori del glutammato sono composti che bloccano l'attività dei recettori del glutammato, i principali recettori dei neurotrasmettitori eccitatori nel cervello. Questi recettori svolgono un ruolo cruciale nella trasmissione sinaptica, nella plasticità, nell'apprendimento e nella memoria. La disregolazione della segnalazione del glutammato è associata a vari disturbi neurologici, come l'epilessia, l'ictus e le malattie neurodegenerative. Gli inibitori dei recettori del glutammato sono essenziali per studiare i meccanismi dell'eccitotossicità e sviluppare strategie neuroprotettive. Presso CymitQuimica, offriamo una gamma di inibitori dei recettori del glutammato per supportare la vostra ricerca sulla funzione sinaptica, la neuroprotezione e i disturbi cognitivi.

Trovati 263 prodotti di "GluR"

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  • HexylHIBO

    CAS:
    HexylHIBO is a type I mGluR antagonist that inhibits mGlu1a and mGlu5a, with Kb values of 140 and 110 μM, respectively.HexylHIBO decreases sEPSC in rats.
    Formula:C12H20N2O4
    Purezza:99.55%
    Colore e forma:Solid
    Peso molecolare:256.3

    Ref: TM-T22840

    1mg
    66,00€
    5mg
    144,00€
    10mg
    207,00€
    25mg
    487,00€
  • (S)-MCPG

    CAS:
    (S)-MCPG is the active isomer of (RS)-MCPG, non-selective group I/group II metabotropic glutamate receptor antagonist.
    Formula:C10H11NO4
    Purezza:98.72%
    Colore e forma:Solid
    Peso molecolare:209.20

    Ref: TM-T13452

    1mg
    35,00€
    5mg
    Prezzo su richiesta
  • DMeOB

    CAS:
    DMeOB (3,3'-Dimethoxybenzaldazine) is a negative regulator with mGluR5 agonist activity and is used in the study of neurological disorders.
    Formula:C16H16N2O2
    Purezza:98.34%
    Colore e forma:Solid
    Peso molecolare:268.31

    Ref: TM-T22736

    2mg
    35,00€
    5mg
    52,00€
    10mg
    85,00€
    25mg
    154,00€
    50mg
    235,00€
    100mg
    376,00€
    200mg
    550,00€
    1mL*10mM (DMSO)
    56,00€
  • A-794282

    CAS:
    A-794282 is a selective antagonist of mGluR1.
    Formula:C19H18N4OS
    Purezza:99.87%
    Colore e forma:Solid
    Peso molecolare:350.44

    Ref: TM-T26486

    1mg
    167,00€
    5mg
    411,00€
    10mg
    562,00€
    25mg
    867,00€
    50mg
    1.121,00€
    100mg
    1.501,00€
  • CBiPES hydrochloride

    CAS:
    CBiPES hydrochloride (CBiPES HCl) is an orthosteric modulator of the mGlu2 receptor and is used to study neurological disorders like epilepsy.
    Formula:C21H20ClN3O2S
    Purezza:99.66%
    Colore e forma:Solid
    Peso molecolare:413.92

    Ref: TM-T22638

    1mg
    60,00€
    5mg
    127,00€
    10mg
    188,00€
    25mg
    393,00€
    50mg
    628,00€
    100mg
    998,00€
    200mg
    1.349,00€
  • CPCCOEt

    CAS:
    CPCCOEt is a low affinity, selective, non-competitive and reversible antagonist of mGluR1b
    Formula:C13H13NO4
    Purezza:99.91%
    Colore e forma:Solid
    Peso molecolare:247.25

    Ref: TM-T22692

    5mg
    52,00€
    10mg
    73,00€
    25mg
    134,00€
    50mg
    212,00€
    100mg
    313,00€
    1mL*10mM (DMSO)
    52,00€
  • S 18986

    CAS:
    S 18986 is a selective, orally active, brain penetrant positive allosteric modulator of AMPA-type receptors, showcasing cognitive-enhancing properties in
    Formula:C10H12N2O2S
    Purezza:99.64%
    Colore e forma:Solid
    Peso molecolare:224.28

    Ref: TM-T16816

    1mg
    35,00€
    5mg
    64,00€
    10mg
    97,00€
    25mg
    Prezzo su richiesta
    50mg
    Prezzo su richiesta
  • VU 0285683

    CAS:
    VU 0285683 is a specific negative allosteric modulator of mGluR5 with a high affinity for the MPEP binding site. VU 0285683 shows anxiolytic-like activity.
    Formula:C14H7FN4O
    Purezza:99.98%
    Colore e forma:Solid
    Peso molecolare:266.23

    Ref: TM-T23509

    2mg
    42,00€
    5mg
    64,00€
    10mg
    79,00€
    25mg
    118,00€
    50mg
    170,00€
    100mg
    235,00€
    200mg
    319,00€
    1mL*10mM (DMSO)
    71,00€
  • Dasolampanel

    CAS:
    Dasolampanel (NGX-426) is an ionotropic glutamate receptor AMPA and Kainate receptor antagonist for the study of chronic pain disorders.
    Formula:C17H20ClN5O3
    Purezza:98.70%
    Colore e forma:Solid
    Peso molecolare:377.83

    Ref: TM-T31208

    1mg
    723,00€
    5mg
    1.510,00€
    25mg
    2.745,00€
    50mg
    3.591,00€
    100mg
    4.940,00€
  • AZD6538

    CAS:
    AZD6538 is an mGluR5 negative allosteric modulator used in the study of CNS-related diseases such as Alzheimer's disease.
    Formula:C15H6FN5O
    Purezza:98.68%
    Colore e forma:Solid
    Peso molecolare:291.24

    Ref: TM-T26719

    5mg
    46,00€
    10mg
    70,00€
    25mg
    126,00€
    50mg
    182,00€
    100mg
    269,00€
  • Dipraglurant

    CAS:
    Dipraglurant: a blood-brain permeable mGluR5 NAM, orally active, selective, IC50 = 21 nM, treats PD-LID.
    Formula:C16H12FN3
    Purezza:98.7%
    Colore e forma:Solid
    Peso molecolare:265.29

    Ref: TM-T15134

    1mg
    97,00€
    5mg
    227,00€
    10mg
    329,00€
    25mg
    723,00€
    50mg
    1.064,00€
    100mg
    1.415,00€
    1mL*10mM (DMSO)
    274,00€
  • Troriluzole

    CAS:
    Troriluzole is a glutamate modulator with anticancer activity and is used in the study of spinocerebellar ataxia.
    Formula:C15H16F3N5O4S
    Purezza:97.14%
    Colore e forma:Solid
    Peso molecolare:419.38

    Ref: TM-T17174

    1mg
    99,00€
    5mg
    235,00€
    10mg
    376,00€
    25mg
    692,00€
    50mg
    1.103,00€
    100mg
    1.644,00€
    1mL*10mM (DMSO)
    259,00€
  • Valiglurax

    CAS:
    Valiglurax (VU2957), potent mGlu4 PAM, crosses blood-brain barrier, orally available; promising for Parkinson's treatment.
    Formula:C16H10F3N5
    Purezza:98.29%
    Colore e forma:Solid
    Peso molecolare:329.28

    Ref: TM-T35028

    10mg
    37,00€
    25mg
    72,00€
    50mg
    111,00€
    1mL*10mM (DMSO)
    34,00€
  • LSN2463359

    CAS:
    LSN2463359 is a positive allosteric modulators of the mGlu5 receptor.
    Formula:C16H15N3O
    Purezza:99.26%
    Colore e forma:Solid
    Peso molecolare:265.31

    Ref: TM-T27854

    2mg
    35,00€
    5mg
    52,00€
    10mg
    85,00€
    25mg
    170,00€
    50mg
    259,00€
    100mg
    383,00€
    200mg
    545,00€
    1mL*10mM (DMSO)
    58,00€
  • AZD 9272

    CAS:
    AZD 9272 is a brain-permeable mGluR5 antagonist for the study of gastroesophageal reflux.
    Formula:C14H6F2N4O
    Purezza:98.29%
    Colore e forma:Solid
    Peso molecolare:284.22

    Ref: TM-T14389

    2mg
    42,00€
    5mg
    65,00€
    10mg
    94,00€
    25mg
    202,00€
    50mg
    304,00€
    100mg
    447,00€
    200mg
    627,00€
  • MNI 137

    CAS:
    <p>MNI 137 is a negative allosteric modulator of mGlu2. MNI 137 inhibits glutamate-induced calcium mobilization with IC50s of 8.3 and 12.6 nM for human and rat.</p>
    Formula:C15H9BrN4O
    Purezza:97.49%
    Colore e forma:Solid
    Peso molecolare:341.16

    Ref: TM-T23010

    1mg
    52,00€
    5mg
    100,00€
    10mg
    123,00€
    25mg
    197,00€
    50mg
    290,00€
    100mg
    393,00€
    200mg
    520,00€
  • ABP688

    CAS:
    ABP688 is a non-competitive and selective mGluR5 antagonist(Ki = 1.7 nM). ABP688 can be used as a PET tracer for clinical imaging.
    Formula:C15H16N2O
    Purezza:98.63%
    Colore e forma:Solid
    Peso molecolare:240.3

    Ref: TM-T26520

    10mg
    44,00€
    25mg
    86,00€
    50mg
    120,00€
    1mL*5mM (DMSO)
    Prezzo su richiesta
  • LY-2300559

    CAS:
    <p>LY-2300559 is an agonist of metabotropic glutamate receptor 2 (mGluR2) and can be used in studies about the treatment of migraine.</p>
    Formula:C26H26O6
    Purezza:99.51%
    Colore e forma:Solid
    Peso molecolare:434.48

    Ref: TM-T27932

    1mg
    333,00€
    5mg
    787,00€
    10mg
    1.074,00€
    25mg
    1.510,00€
    50mg
    1.882,00€
    100mg
    2.375,00€
    500mg
    4.655,00€
  • (E/Z)-SIB-1893

    CAS:
    (E/Z)-SIB-1893 (SIB 1893) is the racemate of (E)-SIB-1893 and (Z)-SIB-1893.
    Formula:C14H13N
    Purezza:99.96%
    Colore e forma:Solid
    Peso molecolare:195.26

    Ref: TM-T23353

    5mg
    73,00€
    10mg
    116,00€
    25mg
    235,00€
    50mg
    373,00€
    100mg
    562,00€
    500mg
    1.216,00€
  • VU0029251

    CAS:
    VU0029251 serves as a partial antagonist of mGluR5, exhibiting a binding affinity with a K i of 1.07 μM.
    Formula:C10H11N3S2
    Colore e forma:Solid
    Peso molecolare:237.34

    Ref: TM-T78600

    1mg
    93,00€
    5mg
    399,00€
    10mg
    685,00€
    25mg
    1.311,00€