
GluR
Gli inibitori dei recettori del glutammato sono composti che bloccano l'attività dei recettori del glutammato, i principali recettori dei neurotrasmettitori eccitatori nel cervello. Questi recettori svolgono un ruolo cruciale nella trasmissione sinaptica, nella plasticità, nell'apprendimento e nella memoria. La disregolazione della segnalazione del glutammato è associata a vari disturbi neurologici, come l'epilessia, l'ictus e le malattie neurodegenerative. Gli inibitori dei recettori del glutammato sono essenziali per studiare i meccanismi dell'eccitotossicità e sviluppare strategie neuroprotettive. Presso CymitQuimica, offriamo una gamma di inibitori dei recettori del glutammato per supportare la vostra ricerca sulla funzione sinaptica, la neuroprotezione e i disturbi cognitivi.
Trovati 263 prodotti di "GluR"
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HexylHIBO
CAS:HexylHIBO is a type I mGluR antagonist that inhibits mGlu1a and mGlu5a, with Kb values of 140 and 110 μM, respectively.HexylHIBO decreases sEPSC in rats.Formula:C12H20N2O4Purezza:99.55%Colore e forma:SolidPeso molecolare:256.3(S)-MCPG
CAS:(S)-MCPG is the active isomer of (RS)-MCPG, non-selective group I/group II metabotropic glutamate receptor antagonist.Formula:C10H11NO4Purezza:98.72%Colore e forma:SolidPeso molecolare:209.20DMeOB
CAS:DMeOB (3,3'-Dimethoxybenzaldazine) is a negative regulator with mGluR5 agonist activity and is used in the study of neurological disorders.Formula:C16H16N2O2Purezza:98.34%Colore e forma:SolidPeso molecolare:268.31Ref: TM-T22736
2mg35,00€5mg52,00€10mg85,00€25mg154,00€50mg235,00€100mg376,00€200mg550,00€1mL*10mM (DMSO)56,00€A-794282
CAS:A-794282 is a selective antagonist of mGluR1.Formula:C19H18N4OSPurezza:99.87%Colore e forma:SolidPeso molecolare:350.44CBiPES hydrochloride
CAS:CBiPES hydrochloride (CBiPES HCl) is an orthosteric modulator of the mGlu2 receptor and is used to study neurological disorders like epilepsy.Formula:C21H20ClN3O2SPurezza:99.66%Colore e forma:SolidPeso molecolare:413.92CPCCOEt
CAS:CPCCOEt is a low affinity, selective, non-competitive and reversible antagonist of mGluR1bFormula:C13H13NO4Purezza:99.91%Colore e forma:SolidPeso molecolare:247.25S 18986
CAS:S 18986 is a selective, orally active, brain penetrant positive allosteric modulator of AMPA-type receptors, showcasing cognitive-enhancing properties inFormula:C10H12N2O2SPurezza:99.64%Colore e forma:SolidPeso molecolare:224.28VU 0285683
CAS:VU 0285683 is a specific negative allosteric modulator of mGluR5 with a high affinity for the MPEP binding site. VU 0285683 shows anxiolytic-like activity.Formula:C14H7FN4OPurezza:99.98%Colore e forma:SolidPeso molecolare:266.23Ref: TM-T23509
2mg42,00€5mg64,00€10mg79,00€25mg118,00€50mg170,00€100mg235,00€200mg319,00€1mL*10mM (DMSO)71,00€Dasolampanel
CAS:Dasolampanel (NGX-426) is an ionotropic glutamate receptor AMPA and Kainate receptor antagonist for the study of chronic pain disorders.Formula:C17H20ClN5O3Purezza:98.70%Colore e forma:SolidPeso molecolare:377.83AZD6538
CAS:AZD6538 is an mGluR5 negative allosteric modulator used in the study of CNS-related diseases such as Alzheimer's disease.Formula:C15H6FN5OPurezza:98.68%Colore e forma:SolidPeso molecolare:291.24Dipraglurant
CAS:Dipraglurant: a blood-brain permeable mGluR5 NAM, orally active, selective, IC50 = 21 nM, treats PD-LID.Formula:C16H12FN3Purezza:98.7%Colore e forma:SolidPeso molecolare:265.29Ref: TM-T15134
1mg97,00€5mg227,00€10mg329,00€25mg723,00€50mg1.064,00€100mg1.415,00€1mL*10mM (DMSO)274,00€Troriluzole
CAS:Troriluzole is a glutamate modulator with anticancer activity and is used in the study of spinocerebellar ataxia.Formula:C15H16F3N5O4SPurezza:97.14%Colore e forma:SolidPeso molecolare:419.38Ref: TM-T17174
1mg99,00€5mg235,00€10mg376,00€25mg692,00€50mg1.103,00€100mg1.644,00€1mL*10mM (DMSO)259,00€Valiglurax
CAS:Valiglurax (VU2957), potent mGlu4 PAM, crosses blood-brain barrier, orally available; promising for Parkinson's treatment.Formula:C16H10F3N5Purezza:98.29%Colore e forma:SolidPeso molecolare:329.28LSN2463359
CAS:LSN2463359 is a positive allosteric modulators of the mGlu5 receptor.Formula:C16H15N3OPurezza:99.26%Colore e forma:SolidPeso molecolare:265.31Ref: TM-T27854
2mg35,00€5mg52,00€10mg85,00€25mg170,00€50mg259,00€100mg383,00€200mg545,00€1mL*10mM (DMSO)58,00€AZD 9272
CAS:AZD 9272 is a brain-permeable mGluR5 antagonist for the study of gastroesophageal reflux.Formula:C14H6F2N4OPurezza:98.29%Colore e forma:SolidPeso molecolare:284.22MNI 137
CAS:<p>MNI 137 is a negative allosteric modulator of mGlu2. MNI 137 inhibits glutamate-induced calcium mobilization with IC50s of 8.3 and 12.6 nM for human and rat.</p>Formula:C15H9BrN4OPurezza:97.49%Colore e forma:SolidPeso molecolare:341.16ABP688
CAS:ABP688 is a non-competitive and selective mGluR5 antagonist(Ki = 1.7 nM). ABP688 can be used as a PET tracer for clinical imaging.Formula:C15H16N2OPurezza:98.63%Colore e forma:SolidPeso molecolare:240.3LY-2300559
CAS:<p>LY-2300559 is an agonist of metabotropic glutamate receptor 2 (mGluR2) and can be used in studies about the treatment of migraine.</p>Formula:C26H26O6Purezza:99.51%Colore e forma:SolidPeso molecolare:434.48Ref: TM-T27932
1mg333,00€5mg787,00€10mg1.074,00€25mg1.510,00€50mg1.882,00€100mg2.375,00€500mg4.655,00€(E/Z)-SIB-1893
CAS:(E/Z)-SIB-1893 (SIB 1893) is the racemate of (E)-SIB-1893 and (Z)-SIB-1893.Formula:C14H13NPurezza:99.96%Colore e forma:SolidPeso molecolare:195.26VU0029251
CAS:VU0029251 serves as a partial antagonist of mGluR5, exhibiting a binding affinity with a K i of 1.07 μM.Formula:C10H11N3S2Colore e forma:SolidPeso molecolare:237.34
