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GluR

GluR

Gli inibitori dei recettori del glutammato sono composti che bloccano l'attività dei recettori del glutammato, i principali recettori dei neurotrasmettitori eccitatori nel cervello. Questi recettori svolgono un ruolo cruciale nella trasmissione sinaptica, nella plasticità, nell'apprendimento e nella memoria. La disregolazione della segnalazione del glutammato è associata a vari disturbi neurologici, come l'epilessia, l'ictus e le malattie neurodegenerative. Gli inibitori dei recettori del glutammato sono essenziali per studiare i meccanismi dell'eccitotossicità e sviluppare strategie neuroprotettive. Presso CymitQuimica, offriamo una gamma di inibitori dei recettori del glutammato per supportare la vostra ricerca sulla funzione sinaptica, la neuroprotezione e i disturbi cognitivi.

Trovati 263 prodotti per "GluR".

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  • Talaglumetad hydrochloride

    CAS:
    Talaglumetad hydrochloride, a prodrug of Eglumegad, targets mGluR2/3 to treat psychiatric disorders.
    Formula:C11H17ClN2O5
    Colore e forma:Solid
    Peso molecolare:292.72

    Ref: TM-T60611

    25mg
    1.369,00€
    50mg
    1.783,00€
    100mg
    2.250,00€
  • MGS-0039

    CAS:
    MGS-0039: Group II mGluR2/3 antagonist, non-serotonergic antidepressant-like effect, AMPA involvement, regulates dopamine in NAc.
    Formula:C15H14Cl2FNO5
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:378.18

    Ref: TM-T28034

    25mg
    1.773,00€
    50mg
    2.322,00€
    100mg
    3.060,00€
  • MFZ 10-7

    CAS:
    MFZ 10-7 is anegative allosteric modulator of the mGluR5.
    Formula:C15H9FN2
    Purezza:99.80%
    Colore e forma:Yellow Solid
    Peso molecolare:236.24

    Ref: TM-T22976

    1mg
    38,00€
    2mg
    52,00€
    5mg
    75,00€
    10mg
    110,00€
    25mg
    245,00€
    50mg
    354,00€
    100mg
    515,00€
    200mg
    700,00€
  • Philanthotoxin 74 dihydrochloride

    CAS:
    Philanthotoxin 74 dihydrochloride is an antagonist of AMPAR with IC50s of 263 and 296 nM for GluR3 and GluR1.
    Formula:C24H44Cl2N4O3
    Purezza:99.75%
    Colore e forma:White Solid
    Peso molecolare:507.54

    Ref: TM-T16524

    50mg
    Prezzo su richiesta
    1mg
    49,00€
    5mg
    139,00€
    1mL*10mM (DMSO)
    180,00€
  • VU6004909

    CAS:
    VU6004909 is an mGlu5 receptor orthosteric modulator that reverses MK801-induced increased cortical activity and cognitive dysfunction.
    Formula:C21H15FN2O4
    Purezza:96.68% - 98.44%
    Colore e forma:Solid
    Peso molecolare:378.35

    Ref: TM-T79784

    2mg
    Prezzo su richiesta
    5mg
    49,00€
    10mg
    79,00€
    25mg
    138,00€
    50mg
    215,00€
    100mg
    344,00€
  • Azotomycin

    CAS:
    Azotomycin is an antagonist of L-glutamine and may be used as an immunosuppressant.
    Formula:C17H23N7O8
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:453.41

    Ref: TM-T26729

    25mg
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    50mg
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    100mg
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  • STAT3-IN-36

    CAS:
    STAT3-IN-36 (compound 11g) is a tritarget inhibitor that selectively targets LRPPRC, STAT3, and CDK1, exhibiting potent anticancer activity. This compound binds to LRPPRC, STAT3, and CDK1, demonstrating more effective anticancer effects than those of TMF or Capecitabine. Additionally, STAT3-IN-36 exhibits an IC50 value of 1.8 μM in HGC27 cells.
    Formula:C30H24F2N2O9S2
    Colore e forma:Solid
    Peso molecolare:658.65

    Ref: TM-T201706

    10mg
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    50mg
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  • BTB01303

    CAS:
    BTB01303 is a glutamate release inhibitor that targets the high levels of glutamate released by cancer cells, which disrupts normal bone turnover and can lead to cancer-induced bone pain. BTB01303 has the potential to improve cancer-induced bone pain [1].
    Formula:C15H11Cl2NO3
    Colore e forma:Solid
    Peso molecolare:324.16

    Ref: TM-T85920

    10mg
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    50mg
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  • YM-202074

    CAS:
    YM-202074: Selective mGlu1 antagonist, binds allosteric site (Ki=4.8 nM), inhibits mGlu1 (IC50=8.6 nM).
    Formula:C22H30N4O2S
    Colore e forma:Solid
    Peso molecolare:414.56

    Ref: TM-T69489

    25mg
    2.043,00€
    50mg
    2.682,00€
    100mg
    3.600,00€
  • CVN636

    CAS:
    CVN636, a potent and selective allosteric agonist for the mGluR7 receptor, exhibits oral activity and CNS permeability [1], with an EC50 of 7 nM for human
    Formula:C19H20FNO4S
    Colore e forma:Solid
    Peso molecolare:377.43

    Ref: TM-T78090

    25mg
    2.538,00€
    50mg
    3.132,00€
    100mg
    3.960,00€
  • LY367385 hydrochloride

    CAS:
    LY367385 hydrochloride: selective mGluR1a antagonist, IC50 = 8.8 μM, neuroprotective, anticonvulsant, antiepileptic.
    Formula:C10H12ClNO4
    Colore e forma:Solid
    Peso molecolare:245.66

    Ref: TM-T60355

    500mg
    1.788,00€
  • LY-2979165

    CAS:
    LY-2979165 is a metabotropic glutamate receptor agonist prodrug.
    Formula:C13H17N5O5S
    Colore e forma:Solid
    Peso molecolare:355.37

    Ref: TM-T70998

    25mg
    2.853,00€
    50mg
    3.763,00€
    100mg
    5.220,00€
  • FP0429

    CAS:
    FP0429 is an agonist of mGlu4.
    Formula:C10H12N2O7
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:272.21

    Ref: TM-T27355

    25mg
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    50mg
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    100mg
    Prezzo su richiesta
  • CPPG

    CAS:
    CPPG: potent group II/III mGlu receptor antagonist, 20x more selective for group III (IC50: 2.2 nM) than II (46.2 nM) in rat cortex.
    Formula:C11H14NO5P
    Colore e forma:Solid
    Peso molecolare:271.21

    Ref: TM-T10880

    1mg
    124,00€
    5mg
    349,00€
    10mg
    623,00€
    25mg
    1.431,00€
  • LY 541850

    CAS:
    LY541850 is a selective orthosteric mGlu2 agonist and mGlu3 antagonist with IC50 values of 0.161 μM and 0.038 μM, respectively.LY 541850 is claimed from human
    Formula:C9H13NO4
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:199.2

    Ref: TM-T11906

    25mg
    2.313,00€
    50mg
    3.042,00€
    100mg
    4.140,00€
  • YM 202074

    CAS:
    metabotropic glutamate receptor type 1 (mGlu1) antagonist
    Formula:C56H72N8O16S2
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:1177.34

    Ref: TM-T23544

    25mg
    2.178,00€
    50mg
    2.862,00€
    100mg
    3.870,00€
  • LY3020371 hydrochloride

    CAS:
    LY3020371 HCl: potent mGlu2/3 antagonist, antidepressant-like; Ki: 5.3/2.5 nM, IC50: 16.2 nM for cAMP inhibition.
    Formula:C15H16ClF2NO5S
    Colore e forma:Solid
    Peso molecolare:395.81

    Ref: TM-T11911

    25mg
    Prezzo su richiesta
    50mg
    Prezzo su richiesta
    100mg
    Prezzo su richiesta
  • Pomaglumetad methionil

    CAS:
    Pomaglumetad methionil is an oral methionine prodrug of the potent specific agonist of mGlu2/3 receptor LY404039.
    Formula:C12H20N2O8S2
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:384.43

    Ref: TM-T12520

    25mg
    Prezzo su richiesta
    50mg
    Prezzo su richiesta
    100mg
    Prezzo su richiesta
  • LY2794193

    CAS:
    LY2794193, a potent and selective mGlu3 receptor agonist, reduces akathisia seizures and increases GAT1, GLAST and GLT-1 protein levels in rats.
    Formula:C16H18N2O6
    Purezza:98.15%
    Colore e forma:White Solid
    Peso molecolare:334.32

    Ref: TM-T15807

    5mg
    1.259,00€
  • PF470

    CAS:
    PF470 (PF-06297470) is a negative allosteric modulator of the metabotropic glutamate receptor 5 (mGluR5), which demonstrated significant therapeutic effects in Parkinson's disease models. However, its clinical development was halted due to potential issues identified in toxicological studies.
    Formula:C18H16N6O
    Colore e forma:Solid
    Peso molecolare:332.36

    Ref: TM-T200534

    25mg
    1.369,00€
    50mg
    1.783,00€
    100mg
    2.250,00€