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GluR

GluR

Gli inibitori dei recettori del glutammato sono composti che bloccano l'attività dei recettori del glutammato, i principali recettori dei neurotrasmettitori eccitatori nel cervello. Questi recettori svolgono un ruolo cruciale nella trasmissione sinaptica, nella plasticità, nell'apprendimento e nella memoria. La disregolazione della segnalazione del glutammato è associata a vari disturbi neurologici, come l'epilessia, l'ictus e le malattie neurodegenerative. Gli inibitori dei recettori del glutammato sono essenziali per studiare i meccanismi dell'eccitotossicità e sviluppare strategie neuroprotettive. Presso CymitQuimica, offriamo una gamma di inibitori dei recettori del glutammato per supportare la vostra ricerca sulla funzione sinaptica, la neuroprotezione e i disturbi cognitivi.

Trovati 263 prodotti per "GluR".

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  • ADX-47273

    CAS:
    ADX-47273 (BA 94673139) is a positive and selective allosteric modulator for the metabotropic glutamate receptor subtype mGluR5(EC50=170 nM).
    Formula:C20H17F2N3O2
    Purezza:97% - 99.22%
    Colore e forma:White Solid
    Peso molecolare:369.36

    Ref: TM-T2053

    2mg
    37,00€
    5mg
    52,00€
    1mL*10mM (DMSO)
    56,00€
    10mg
    82,00€
    25mg
    158,00€
    50mg
    284,00€
    100mg
    512,00€
  • AZD-8529

    CAS:
    AZD-8529: selective, oral mGluR2 modulator, EC50 285 nM; inactive on mGluR1,3-8 at 20-25 M.
    Formula:C24H24F3N5O3
    Colore e forma:Solid
    Peso molecolare:487.47

    Ref: TM-T10432

    25mg
    1.603,00€
    50mg
    2.088,00€
    100mg
    3.168,00€
  • VU0361737

    CAS:
    VU0361737 (ML-128) is a mGlu4 PAM; EC50 is 240 nM (human) and 110 nM (rat), weak at mGlu5/8, inactive at mGlu1/2/3/6/7, CNS-penetrant.
    Formula:C13H11ClN2O2
    Purezza:99.60% - 99.85%
    Colore e forma:Solid
    Peso molecolare:262.69

    Ref: TM-T6726

    1mL*10mM (DMSO)
    33,00€
    25mg
    44,00€
    50mg
    69,00€
    100mg
    100,00€
    500mg
    236,00€
  • CX614

    CAS:
    CX614 is a positive allosteric modulator of the AMPA receptor concerning AMPA.
    Formula:C13H13NO4
    Purezza:97.37%
    Colore e forma:White Solid
    Peso molecolare:247.25

    Ref: TM-T19698

    5mg
    52,00€
    1mL*10mM (DMSO)
    55,00€
    10mg
    78,00€
    25mg
    119,00€
    50mg
    172,00€
    100mg
    259,00€
    200mg
    388,00€
  • LY-404187

    CAS:
    LY404187 is a positive allosteric modulator of AMPA receptors
    Formula:C19H22N2O2S
    Purezza:99.34%
    Colore e forma:White Solid
    Peso molecolare:342.46

    Ref: TM-T7706

    2mg
    34,00€
    5mg
    50,00€
    1mL*10mM (DMSO)
    55,00€
    10mg
    86,00€
    25mg
    156,00€
    50mg
    225,00€
    100mg
    321,00€
    200mg
    447,00€
  • NBQX

    CAS:
    NBQX (FG9202) is a potent, selective and competitive AMPA receptor antagonist. Neuroprotective and anticonvulsant; active in vivo.
    Formula:C12H8N4O6S
    Purezza:97.66% - 99.93%
    Colore e forma:Solid
    Peso molecolare:336.28

    Ref: TM-T4113

    1mg
    38,00€
    2mg
    50,00€
    5mg
    84,00€
    1mL*10mM (DMSO)
    92,00€
    10mg
    114,00€
    25mg
    222,00€
    50mg
    334,00€
    100mg
    497,00€
    200mg
    717,00€
  • trans-ACPD

    CAS:
    trans-ACPD ((±)-trans-ACPD) is an equimolecular mixture of (1S, 3R)- and (1R, 3S)-ACPD.
    Formula:C7H11NO4
    Purezza:99.98%
    Colore e forma:White Solid
    Peso molecolare:173.17

    Ref: TM-T3484

    1mg
    46,00€
    2mg
    59,00€
    1mL*10mM (DMSO)
    71,00€
    5mg
    94,00€
    10mg
    140,00€
    25mg
    264,00€
    50mg
    477,00€
    100mg
    692,00€
  • MPEP

    CAS:
    MPEP is a selective mGlu5 receptor antagonist with IC50 of 36 nM, exhibits no appreciable activity at mGlu1b/2/3/4a/7b/8a/6 receptors.
    Formula:C14H11N
    Purezza:99.54%
    Colore e forma:White Solid
    Peso molecolare:193.24

    Ref: TM-T6598

    10mg
    46,00€
    25mg
    80,00€
    50mg
    130,00€
    100mg
    200,00€
    200mg
    295,00€
    500mg
    497,00€
  • HBT1

    CAS:
    HBT1 is an AMPA receptor potentiator that induces production of brain-derived neurotrophic factor (BDNF) and exhibits little agonistic effect in primary neurons
    Formula:C16H17F3N4O2S
    Purezza:99.52%
    Colore e forma:White Solid
    Peso molecolare:386.39

    Ref: TM-T8779

    1mL*10mM (DMSO)
    33,00€
    25mg
    49,00€
    50mg
    73,00€
    100mg
    111,00€
  • VU0364770

    CAS:
    VU0364770 (VU 0364770)(EC50=1.1 μM), a positive allosteric modulator(PAM) of mGlu4, shows insignificant activity at 68 other receptors, including other mGlu
    Formula:C12H9ClN2O
    Purezza:99.65% - 99.96%
    Colore e forma:White Solid
    Peso molecolare:232.67

    Ref: TM-T6727

    1mL*10mM (DMSO)
    33,00€
    10mg
    34,00€
    25mg
    44,00€
    50mg
    73,00€
    100mg
    103,00€
    500mg
    245,00€
  • TCN238

    CAS:
    TCN238 is an orally bioavailable positive allosteric modulator of the metabotropic glutamate receptor 4 (mGluR4with an EC50 of 1 μM).
    Formula:C12H11N3
    Purezza:99.9% - 99.92%
    Colore e forma:White Solid
    Peso molecolare:197.24

    Ref: TM-T7494

    5mg
    34,00€
    1mL*10mM (DMSO)
    38,00€
    10mg
    55,00€
    25mg
    104,00€
    50mg
    172,00€
    100mg
    299,00€
    200mg
    432,00€
  • pep2-EVKI acetate(1315378-67-6 free base)


    Pep2-EVKI acetate, a cell-permeable peptide, disrupts PICK1-GluR2 AMPA receptor binding.
    Formula:C64H99N13O21
    Purezza:99.85%
    Colore e forma:White Solid
    Peso molecolare:1386.55

    Ref: TM-TP1943L1

    1mg
    94,00€
    5mg
    193,00€
    10mg
    290,00€
    25mg
    469,00€
    50mg
    637,00€
    100mg
    858,00€
  • CTEP

    CAS:
    CTEP (RO 4956371) (RO4956371) is a novel, long-acting, orally bioavailable allosteric antagonist of mGlu5 receptor with IC50 of 2.2 nM, shows >1000-fold
    Formula:C19H13ClF3N3O
    Purezza:99.17%
    Colore e forma:Solid
    Peso molecolare:391.77

    Ref: TM-T6457

    2mg
    34,00€
    5mg
    50,00€
    1mL*10mM (DMSO)
    55,00€
    10mg
    88,00€
    25mg
    138,00€
    50mg
    244,00€
    100mg
    330,00€
    200mg
    470,00€
  • Lu AF21934

    CAS:
    Lu AF21934 is a brain-penetrant and selective mGlu4 receptor positive allosteric modulator (IC50: 500 nM, human).
    Formula:C14H16Cl2N2O2
    Purezza:99.01%
    Colore e forma:Solid
    Peso molecolare:315.2

    Ref: TM-T3539

    1mg
    35,00€
    5mg
    74,00€
    1mL*10mM (DMSO)
    74,00€
    10mg
    120,00€
    25mg
    219,00€
    50mg
    349,00€
    100mg
    557,00€
  • IDRA-21

    CAS:
    IDRA-21 is a positive AMPA receptor modulator.
    Formula:C8H9ClN2O2S
    Purezza:99.73%
    Colore e forma:White Solid
    Peso molecolare:232.69

    Ref: TM-T7823

    1mL*10mM (DMSO)
    33,00€
    100mg
    34,00€
    500mg
    84,00€
    1g
    110,00€
    2g
    161,00€
  • Ro0711401

    CAS:
    Ro0711401 is an agonist of mGlu1 receptor.
    Formula:C18H11F3N2O3
    Purezza:97.57%
    Colore e forma:Solid
    Peso molecolare:360.29

    Ref: TM-T9021

    2mg
    34,00€
    5mg
    49,00€
    1mL*10mM (DMSO)
    50,00€
    10mg
    75,00€
    25mg
    145,00€
    50mg
    225,00€
    100mg
    371,00€
  • VU 0357121

    CAS:
    VU0357121, a positive allosteric modulator of mGlu5 (EC50: 33 nM), is inactive or very weakly antagonizing at other mGlu receptor subtypes.
    Formula:C17H17F2NO2
    Purezza:99% - 99.98%
    Colore e forma:Solid
    Peso molecolare:305.32

    Ref: TM-T6725

    2mg
    39,00€
    5mg
    56,00€
    1mL*10mM (DMSO)
    56,00€
    10mg
    90,00€
    25mg
    172,00€
    50mg
    266,00€
    100mg
    416,00€
  • YM90K

    CAS:
    YM90K (6-(1H-imidazol-1-yl)-7-nitro-2,3(1H,4H)-) hydrochloride is an antagonist of AMPA receptor.
    Formula:C11H8ClN5O4
    Purezza:98.23%
    Colore e forma:Solid
    Peso molecolare:309.66

    Ref: TM-T8435

    1mg
    73,00€
    5mg
    160,00€
    1mL*10mM (DMSO)
    170,00€
    10mg
    245,00€
    25mg
    404,00€
    50mg
    567,00€
    100mg
    767,00€
    200mg
    1.018,00€
  • FITM

    CAS:
    FITM is a potent negative allosteric modulator of mGlu1 receptor(Ki : 2.5 nM).
    Formula:C18H18FN5OS
    Purezza:97.25% - 99.23%
    Colore e forma:White Solid
    Peso molecolare:371.43

    Ref: TM-T7292

    1mg
    34,00€
    2mg
    44,00€
    1mL*10mM (DMSO)
    62,00€
    5mg
    66,00€
    10mg
    92,00€
    25mg
    177,00€
    50mg
    268,00€
    100mg
    394,00€
  • CX516

    CAS:
    CX516 (Ampalex), an ampakine and nootropic, acts as an AMPA receptor positive allosteric modulator as a therapy for Alzheimer's disease, schizophrenia and MCI.
    Formula:C14H15N3O
    Purezza:99.57% - ≥95%
    Colore e forma:White Solid
    Peso molecolare:241.29

    Ref: TM-T1884

    10mg
    33,00€
    1mL*10mM (DMSO)
    33,00€
    25mg
    43,00€
    50mg
    62,00€
    100mg
    79,00€
    200mg
    126,00€