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AChR

AChR

Gli inibitori del recettore dell'acetilcolina (AChR) sono composti che bloccano l'attività dei recettori dell'acetilcolina, fondamentali per la neurotrasmissione nei sistemi nervoso centrale e periferico. Gli AChR svolgono un ruolo cruciale nella contrazione muscolare, nella memoria e nelle funzioni cognitive. Gli inibitori degli AChR vengono utilizzati per studiare condizioni come la miastenia grave, l'Alzheimer e altri disturbi neurologici. Modulando l'attività degli AChR, questi inibitori possono aiutare a svelare le complessità della segnalazione colinergica nel cervello. Presso CymitQuimica, offriamo una gamma di inibitori degli AChR per supportare la tua ricerca in neuroscienze, farmacologia e malattie neurodegenerative.

Trovati 617 prodotti di "AChR"

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  • 3-hydroxy Darifenacin

    CAS:
    3-hydroxy Darifenacin, darifenacin metabolite, blocks M1-5 muscarinic receptors with varying potency (Kis: 2.24-79.43 nM) in CHO cells.
    Formula:C28H30N2O3
    Colore e forma:Solid
    Peso molecolare:442.559
  • 8-Aminoadenine

    CAS:
    <p>8-Aminoadenine (7H-purine-6,8-diamine) is a ligand for Adenine Receptor with Ki of 0.0341 μM.</p>
    Formula:C5H6N6
    Purezza:99.82%
    Colore e forma:Solid
    Peso molecolare:150.14
  • Migrastatin

    CAS:
    Migrastatin is a bacterial metabolite that has been found inStreptomyceswith antimuscarinic and anticancer activities.1,2It binds to M1-5muscarinic
    Formula:C27H39NO7
    Colore e forma:Solid
    Peso molecolare:489.609
  • Cyclodrine

    CAS:
    <p>Cyclodrine (Cyclopent) is a cholinergic (muscarinic, nicotinic) (mAChR and nAChR) receptor antagonist.</p>
    Formula:C19H29NO3
    Purezza:97.62%
    Colore e forma:Soild
    Peso molecolare:319.44
  • VU6028418

    CAS:
    VU6028418 is a highly selective, potent, orally active M4mAChR antagonist that acts on hM4 (IC50: 4.1 nM).
    Colore e forma:Solid
  • DSPE-PEG5000-RVG29


    DSPE-PEG5000-RVG29 is a PEG compound comprised of DSPE and rabies virus glycoprotein 29 (RVG29). RVG29 specifically binds to nicotinic acetylcholine receptors (nAChR) at the blood-brain barrier (BBB) and facilitates passage through the BBB.
    Colore e forma:Odour Solid
  • [Ala2,8,9,11,19,22,24,25,27,28]-VIP

    CAS:
    [Ala2,8,9,11,19,22,24,25,27,28]-VIP can be used for related research in the field of life sciences. Its product number is T36637 and CAS number is 866552-34-3.
    Formula:C131H219N41O33S
    Colore e forma:Solid
    Peso molecolare:2928.51
  • Muscarinic toxin 3

    CAS:
    Muscarinic toxin 3 (MT3), a potent non-competitive antagonist of mAChR and adrenoceptors, exhibits pIC50 values of 6.71 for M1, 8.79 for M4, 8.86 for α1A, 7.57
    Formula:C319H489N89O97S8
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:7379.35
  • TC-2216

    CAS:
    <p>TC-2216 is a partial agonist at the neural nicotinic acetylcholine receptor and is used to treat anxiety and depression.</p>
    Formula:C12H17N3
    Purezza:99.33%
    Colore e forma:Solid
    Peso molecolare:203.28
  • Octamylamine

    CAS:
    Octamylamine is a bioactive chemical.
    Formula:C13H29N
    Colore e forma:Solid
    Peso molecolare:199.3761
  • nAChR modulator-2

    CAS:
    nAChR modulator-2, a insecticide, is a insect nAChR orthosteric modulator [1] .
    Formula:C12H8ClN3O2
    Colore e forma:Solid
    Peso molecolare:261.66
  • nAChR agonist 2

    CAS:
    Compound 8, identified as a selective alpha4beta2 (α4β2) neuronal acetylcholine receptor (nAChR) agonist, demonstrates a dissociation constant (Kd) of 26 nM,
    Formula:C11H16N2
    Colore e forma:Solid
    Peso molecolare:176.263
  • TIP 39, Tuberoinfundibular Neuropeptide

    CAS:
    TIP39 is a synthetic neuropeptide agonist for human and rat PTH2 receptors from the hypothalamus.
    Formula:C202H325N61O54S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:4504.2
  • PF-4348235 HCl


    <p>PF-4348235 HCl (β2AR/M-receptor agonist-2 HCl) is a muscarinic M3 receptor antagonist (Ki: 0.73 nM) and β2 adrenergic receptor agonist (MABA, EC50: 3.7 nM). PF-4348235 HCl is also a bronchial BM213 acetate is a bronchodilator used to study cardiovascular and respiratory diseases such as chronic obstructive pulmonary disease (COPD).</p>
    Formula:C36H50Cl2N4O7S
    Purezza:98.81%
    Colore e forma:Solid
    Peso molecolare:753.78
  • Lupanine hydrochloride

    CAS:
    Lupanine hydrochloride, a Sparteine derivative, binds to nAChR with a Ki of 500 nM and has ganglioplegic properties.
    Formula:C15H25ClN2O
    Colore e forma:Solid
    Peso molecolare:284.83
  • Imidafenacin Metabolite M4

    CAS:
    Imidafenacin M4 is a CYP3A4-formed metabolite of the muscarinic antagonist imidafenacin.
    Formula:C18H19N3O3
    Colore e forma:Solid
    Peso molecolare:325.368
  • M1/M4 muscarinic agonist 2


    Compound 40 is a selective M1/M4 muscarinic antagonist with an IC50 of 19 nM for M1 receptors and 42 nM for M4 receptors [1].
    Colore e forma:Odour Solid
  • Tropicamide

    CAS:
    Tropicamide (Ro 1-7683), a synthetic atropine-like muscarinic antagonist, dilates pupils and paralyzes eye muscles for diagnostic use.
    Formula:C17H20N2O2
    Purezza:99.78% - 99.94%
    Colore e forma:White Powder
    Peso molecolare:284.35
  • CDD0102 HCl

    CAS:
    CDD0102 HCl is a selective and potent M1 muscarinic receptor agonist for the treatment of Alzheimer's disease.
    Formula:C8H13ClN4O
    Purezza:99.7%
    Colore e forma:Soild
    Peso molecolare:216.67
  • sabcomeline

    CAS:
    Sabcomeline: potent, selective M1 agonist; boosts cognition; for Alzheimer's study.
    Formula:C10H15N3O
    Colore e forma:Solid
    Peso molecolare:193.25
  • Flupyradifurone

    CAS:
    <p>Flupyradifurone (flupyradifurone) is a systemic insecticide and nicotinic acetylcholine receptor (nAChR) agonist interfer nervous system of insects.</p>
    Formula:C12H11ClF2N2O2
    Purezza:99.83%
    Colore e forma:Solid
    Peso molecolare:288.68
  • [D-Trp7,9,10]-Substance P

    CAS:
    <p>Substance P analog that inhibits activation of Gq/11 by M1 muscarinic ACh receptors. Does not inhibit Gi/o activation by M2 ACh receptors.</p>
    Formula:C79H105N21O13S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:1588.89
  • Small Cardioactive Peptide B (SCPB)

    CAS:
    SCPB: neurally active peptide, boosts adenylate cyclase in heart/gills, EC50s: 0.1 μM (heart), 1.0 μM (gills).
    Formula:C52H80N14O11S2
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:1141.41
  • β2AR/M-receptor agonist-1

    CAS:
    β2AR/M-receptor agonist-1 (example 131), a muscarinic antagonist and β2 adrenoceptor agonist (MABA), exhibits dual potency towards β2 adrenoceptor and
    Formula:C43H56BrN3O7
    Colore e forma:Solid
    Peso molecolare:806.82
  • 5-AAM-2-CP

    CAS:
    5-AAM-2-CP is one of the major metabolites of Acetamiprid. Acetamiprid, a nAChR agonist, is a neonicotinoid insecticide used worldwide.
    Formula:C8H9ClN2O
    Purezza:99.58%
    Colore e forma:Solid
    Peso molecolare:184.62
  • Dicloromezotiaz

    CAS:
    Dicloromezotiaz: Potent insecticide targeting nAChRs, controls various lepidoptera.
    Formula:C19H12Cl3N3O2S
    Colore e forma:Solid
    Peso molecolare:452.74
  • (+)-Coclaurine hydrochloride

    CAS:
    (+)-Coclaurine hydrochloride, also known as (+)-(R)-Coclaurine, is a benzyltetrahydroisoquinoline alkaloid extracted from multiple plant species.
    Formula:C17H20ClNO3
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:321.8
  • Ebiratide

    CAS:
    Ebiratide is an analog of ACTH 4-9.
    Formula:C48H73N11O10S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:996.23
  • Destomycin A

    CAS:
    Destomycin A, an aminoglycoside antibiotic, exhibits activity against bacterial (Gram-positive and Gram-negative), antifungal, and anthelmintic agents. It inhibits peptide synthesis in Escherichia coli cells and stimulates adenylate cyclase in animal tissues.
    Formula:C20H37N3O13
    Colore e forma:Solid
    Peso molecolare:527.52
  • Proadrenomedullin (1-20), human

    CAS:
    Endogenous peptide; agonist of MRGPRX2 (EC50=251 nM); noncompetitive inhibitor of nicotinic receptors; reduces catecholamine secretion; antihypertensive.
    Formula:C112H178N36O27
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:2460.84
  • Mant-GTPγS

    CAS:
    <p>Mant-GTPγS, an effective GTP analog, displays strong competitive inhibition of adenylyl cyclase (AC). Additionally, it acts as a potent inhibitor of YdeH.</p>
    Formula:C18H23N6O14P3S
    Colore e forma:Solid
    Peso molecolare:672.39
  • Anabaseine

    CAS:
    Anabaseine is a broad nicotinic agonist, favoring alpha-7 AChRs in muscle/brain, and weakly stimulates alpha-4 beta-2 nAChRs.
    Formula:C10H12N2
    Colore e forma:Solid
    Peso molecolare:160.22
  • Fentonium bromide

    CAS:
    <p>Fentonium bromide is a biochemical.</p>
    Formula:C31H34BrNO4
    Colore e forma:Solid
    Peso molecolare:564.51
  • Pozanicline hydrochloride


    Pozanicline hydrochloride is an oral α4β2 nAChR agonist with a 16.7 nM Ki, insignificantly binding to α7 nAChR.
    Formula:C11H17ClN2O
    Purezza:97.13% - 99.81%
    Colore e forma:Solid
    Peso molecolare:228.72
  • Methyllycaconitine citrate

    CAS:
    <p>Methyllycaconitine citrate (MLA) is an α7 neuronal nicotinic acetylcholine receptor (α7nAChR) antagonist that crosses the blood-brain barrier.</p>
    Formula:C43H58N2O17
    Purezza:98.03% - 98.91%
    Colore e forma:Solid
    Peso molecolare:874.92
  • N,N-Dicyclohexylcarbodiimide

    CAS:
    N,N-Dicyclohexylcarbodiimide (Dicyclohexylcarbodiimide) is a cross-linking agent used in the synthesis of active ester-containing reagents.
    Formula:C13H22N2
    Purezza:98.28% - 99.73%
    Colore e forma:Solid
    Peso molecolare:206.33
  • TC-2559 difumarate

    CAS:
    TC-2559 difumarate: Oral α4β2 nAChR partial agonist, CNS-selective, EC50 0.18 μM, prefers α4β2 over α2β4/α4β4/α3β4, antinociceptive.
    Formula:C20H26N2O9
    Colore e forma:Solid
    Peso molecolare:438.43
  • Oxotremorine

    CAS:
    Oxotremorine acts as an agonist of mAChR, specifically activating the M1 and M3 acetylcholine receptors. In drug discrimination experiments with macaques, it exhibits effects similar to nicotine.
    Formula:C12H18N2O
    Colore e forma:Solid
    Peso molecolare:206.28
  • 5-Hydroxymethyl tolterodine formate

    CAS:
    <p>5-Hydroxymethyl tolterodine (formate) (PNU-200577 (formic)) is an active metabolite of the muscarinic acetylcholine receptor antagonists Tolterodine and Fesoterodine. It is synthesized by the cytochrome P450 (CYP) isoenzyme CYP2D6 and plasma esterases.</p>
    Formula:C23H33NO4
    Colore e forma:Solid
    Peso molecolare:387.51
  • 5-AMAM-2-CP

    CAS:
    <p>5-AMAM-2-CP, a significant metabolite of Acetamiprid, serves as a global insecticide within the neonicotinoid class and acts as an nAChR agonist [1] [2].</p>
    Formula:C9H11ClN2O
    Colore e forma:Solid
    Peso molecolare:198.65
  • Epiboxidine

    CAS:
    Epiboxidine: Potent, selective nAChR agonist; Ki 0.46/1.2 nM for rat/human α4β2; analogous to Epibatidine and ABT 418.
    Formula:C10H14N2O
    Colore e forma:Solid
    Peso molecolare:178.23
  • M4 mAChR agonist-1 

    CAS:
    <p>M4 mAChR agonist-1 (4-Piperidinecarboxamide, 1-(5,6-dimethylthieno[2,3-d]pyrimidin-4-yl)-) is an effective agonist of M4 mAChR (EC50 &gt;10 μM).</p>
    Formula:C14H18N4OS
    Purezza:99.14%
    Colore e forma:Solid
    Peso molecolare:290.38
  • bPiDDB

    CAS:
    <p>bPiDDB (N,N'-Dodecylbis-Picolinium Bromide) is a nicotinic receptor (nAChR) antagonist.</p>
    Formula:C24H38Br2N2
    Purezza:98.72%
    Colore e forma:Solid
    Peso molecolare:514.38
  • (Rac)-5-Hydroxymethyl Tolterodine hydrochloride

    CAS:
    <p>(Rac)-5-Hydroxymethyl Tolterodine HCl, or (Rac)-Desfesoterodine HCl, is a potent mAChR blocker researched for overactive bladder.</p>
    Formula:C22H32ClNO2
    Colore e forma:Solid
    Peso molecolare:377.95
  • Navafenterol saccharinate

    CAS:
    AZD-8871 saccharinate is a dual-acting bronchodilator which may be useful in the treatment of Chronic Obstructive Pulmonary Disease (COPD).
    Formula:C45H47N7O9S3
    Colore e forma:Solid
    Peso molecolare:926.09
  • Muscarine

    CAS:
    Muscarine is a toxic alkaloid found in Amanita muscaria and other fungi of the Inocybe species.
    Formula:C9H20NO2
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:174.26
  • (R)-(+)-Anatabine

    CAS:
    (R)-(+)-Anatabine is an less active R-enantiomer of Anatabine. Anatabine is a potent agonist of α4β2 nAChR.
    Formula:C10H12N2
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:160.22
  • Irsogladine maleate

    CAS:
    Compound PDK0375, with CAS No. 84504-69-8, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0375 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.
    Formula:C9H7Cl2N5
    Colore e forma:Solid
    Peso molecolare:256.09
  • trans-Cevimeline hydrochloride

    CAS:
    <p>AF 102A hydrochloride is a biochemical.</p>
    Formula:C10H18ClNOS
    Colore e forma:Solid
    Peso molecolare:235.77
  • (R)-Dinotefuran

    CAS:
    (R)-Dinotefuran, a neonicotinoid, is 1.7-2.4x more effective against pests like Aphis gossypii and safer for bees.
    Formula:C7H14N4O3
    Colore e forma:Solid
    Peso molecolare:202.21
  • Hydroxybupropion

    CAS:
    Hydroxybupropion is the major active metabolite of Bupropion and an antagonist of nACh receptor. Hydroxybupropion inhibits norepinephrine uptake (IC50 = 1.7 μM).
    Formula:C13H18ClNO2
    Purezza:99.73%
    Colore e forma:Off-White Solid
    Peso molecolare:255.74
  • DSPE-PEG2000-RVG29


    <p>DSPE-PEG2000-RVG29 is a PEG compound composed of DSPE and rabies virus glycoprotein 29 (RVG29). RVG29 specifically binds to nicotinic acetylcholine receptors (nAChR) at the blood-brain barrier (BBB) and can traverse the BBB.</p>
    Colore e forma:Odour Solid
  • NNC 11-1607

    CAS:
    NNC 11-1607 is a functionally selective agonist of M(1)/M(4) mAChR.
    Formula:C30H32N6O2S2
    Colore e forma:Solid
    Peso molecolare:572.74
  • Ebiratide TFA


    <p>Ebiratide (HOE-427) TFA is a derivative of ACTH4-9 that exerts its effect directly on the central nervous system, enhancing memory. Ebiratide TFA also promotes the metabolism of acetylcholine (ACh) in the rat brain.</p>
    Formula:C48H73N11O10S·xC2HF3O2
    Colore e forma:Solid
    Peso molecolare:996.23 (free base)
  • RuBi-Nicotine

    CAS:
    Nicotinic receptor agonist
    Formula:C40H44Cl2N8Ru
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:808.81
  • PF-06827443


    PF-06827443 is a orally bioavailable, CNS-penetrant M1-selective PAM with minimal agonist activity.
    Formula:C24H24N2O4
    Colore e forma:Solid
    Peso molecolare:404.47
  • Lobeline sulfate

    CAS:
    Lobeline sulfate, an alkaloid like nicotine, aids in smoking cessation, insomnia, and respiratory issues. Less potent on nicotinic receptors.
    Formula:C22H29NO6S
    Purezza:98%
    Colore e forma:White Powder
    Peso molecolare:435.54
  • (Rac)-5-Carboxy tolterodine

    CAS:
    <p>(Rac)-5-Carboxy tolterodine is an inactive metabolite of Tolterodine, which acts as a muscarinic acetylcholine receptor antagonist.</p>
    Formula:C22H29NO3
    Colore e forma:Solid
    Peso molecolare:355.47
  • Tiquizium

    CAS:
    <p>Tiquizium has effective Antimuscarinic effect, and causes significant bronchodilation in patients with chronic obstructive pulmonary disease.</p>
    Formula:C19H24NS2
    Purezza:99.82%
    Colore e forma:Solid
    Peso molecolare:330.53
  • Lu AE51090

    CAS:
    Lu AE51090 is a selective muscarinic M1 receptor agonist with minimal off-target effects, receptor function and selective pharmacological modulation.
    Formula:C24H29N3O3
    Purezza:99.57%
    Colore e forma:Solid
    Peso molecolare:407.51
  • Angiopeptin

    CAS:
    <p>Angiopeptin is a synthetic octapeptide analog of somatostatin; suppresses accelerated transplant atherosclerosis in rabbit heart arteries.</p>
    Formula:C54H71N11O10S2
    Colore e forma:Solid
    Peso molecolare:1098.34
  • R-(+)-Cotinine

    CAS:
    <p>R-(+)-Cotinine, an inactive nicotine metabolite, boosts Ach-induced current in human α7 nAChRs.</p>
    Formula:C10H12N2O
    Colore e forma:Solid
    Peso molecolare:176.22
  • Bensultap

    CAS:
    Bensultap is an agricultural chemical typically used as a pesticide.
    Formula:C17H21NO4S4
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:431.61
  • Perindoprilat

    CAS:
    Perindoprilat (Perindoprilate) is an angiotensin-converting enzyme inhibitor.
    Formula:C17H28N2O5
    Purezza:99.48%
    Colore e forma:Solid
    Peso molecolare:340.41
  • Aceclidine (hydrochloride)

    CAS:
    agonist of muscarinic receptors
    Formula:C9H16ClNO2
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:205.68
  • α-Conotoxin PIA

    CAS:
    Selective antagonist of α6-containing nicotinic receptors that discriminates between the closely related α6 and α3 subunits (IC50 values are 0.95 and 74.2 nM
    Formula:C79H125N27O25S4
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:1981.3
  • G-Protein antagonist peptide

    CAS:
    Peptide inhibits G protein-receptor binding; competitively blocks M2 and β-adrenoceptor-induced Gs/Gi/Go activation.
    Formula:C57H64N12O9S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:1093.27
  • α-Muricholic acid

    CAS:
    α-Muricholic acid is the most abundant primary bile acid in rodents.
    Formula:C24H40O5
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:408.57
  • GeX-2

    CAS:
    <p>GeX-2 is a truncated analogue of αO-conotoxin. It has the ability to activate GABAB receptors and inhibit α9α10nAChR as well as CaV2.2 channels. Additionally, GeX-2 is effective in alleviating pain in a rat model of chronic constriction injury.</p>
    Formula:C103H169N43O27
    Colore e forma:Solid
    Peso molecolare:2441.72
  • TDI-10229

    CAS:
    <p>TDI-10229: potent oral sAC inhibitor, IC50=195 nM. Good mouse pharmacokinetics for in vivo use.</p>
    Formula:C16H16ClN5
    Purezza:99.85% - 99.89%
    Colore e forma:Soild
    Peso molecolare:313.78
  • Soclenicant

    CAS:
    Soclenicant is a negative-altering modulator of α 7 -nAChR for anxiety, depression, and PTSD, due to its high selectivity, oral availability
    Formula:C24H26N4O3
    Purezza:99.57%
    Colore e forma:Soild
    Peso molecolare:418.49
  • M3/PDE4 modulator-1


    M3/PDE4 Modulator-1 (compound 10f) serves as a bifunctional entity functioning both as an M3 mAChR antagonist and a PDE4 inhibitor.
    Formula:C38H41Cl2N3O8S
    Colore e forma:Solid
    Peso molecolare:770.72
  • α-Conotoxin EI

    CAS:
    Selective antagonist of neuromuscular nicotinic receptors α1β1γδ
    Formula:C83H125N27O27S5
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:2093.37
  • Methylatropine (nitrate)

    CAS:
    Methylatropine: Muscarinic antagonist, <0.1 nM IC50, atropine derivative, lowers ACh's effect on BP, affects salivation, pupil dilation, heart rate.
    Formula:C18H26N2O6
    Colore e forma:Solid
    Peso molecolare:366.414
  • M 8218

    CAS:
    M 8218 is a bioactive chemical.
    Formula:C20H29NO2
    Colore e forma:Solid
    Peso molecolare:315.45
  • BTMPS

    CAS:
    <p>BTMPS is a usage-dependent nicotinic antagonist capable of reducing acute withdrawal symptoms associated with morphine use.</p>
    Formula:C28H52N2O4
    Purezza:98.1%
    Colore e forma:Solid
    Peso molecolare:480.72
  • Thiothixene

    CAS:
    Thiothixene has a wide range of applications in life science related research.
    Formula:C23H29N3O2S2
    Colore e forma:Solid
    Peso molecolare:443.62
  • LAS190792

    CAS:
    LAS190792 (AZD8999) is a dual muscarinic antagonist/β2-agonist, pIC50s (M1-M5, β1-β3): 8.9-5.6; used as a bronchodilator.
    Formula:C39H43ClN4O9S2
    Colore e forma:Solid
    Peso molecolare:811.36
  • Emraclidine

    CAS:
    Emraclidine (CVL-231) is a novel, highly selective allosteric modulator of the muscarinic M4 receptor positive receptor.Cost-effective and quality-assured.
    Formula:C20H21F3N4O
    Purezza:99.96%
    Colore e forma:Solid
    Peso molecolare:390.4
  • nAChR modulator-1

    CAS:
    nAChR modulator-1, a insecticide, is a insect nAChR orthosteric modulator [1] .
    Formula:C12H8ClN3O2
    Colore e forma:Solid
    Peso molecolare:261.66
  • Biperiden Hydrochloride

    CAS:
    <p>Biperiden HCl is an anti-Parkinson's drug, blocks M1 receptors, manages all Parkinson's types, and is FDA-approved. Non-toxic at 0.11 mg/kg to rats' cognition.</p>
    Formula:C21H30ClNO
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:347.92
  • Epiboxidine hydrochloride

    CAS:
    Epiboxidine HCl: potent α4β2 nAChR agonist; Ki 0.46 nM (rat), 1.2 nM (human); Epibatidine analog.
    Formula:C10H15ClN2O
    Colore e forma:Solid
    Peso molecolare:214.69
  • LtIA-F


    LtIA-F, a fluorescent LtIA derivative, aids study of α3β2 nAChR's structure, distribution, and binding domain.
    Formula:C86H121N25O22S4
    Colore e forma:Solid
    Peso molecolare:1985.31
  • ANQ-9040

    CAS:
    <p>ANQ-9040 is a nondepolarizing neuromuscular relaxant of the steroid class.</p>
    Formula:C36H58N2O5S
    Colore e forma:Solid
    Peso molecolare:630.92
  • (S)-Dinotefuran

    CAS:
    (S)-Dinotefuran, a neonicotinoid, more toxic to bees than its R-isomer, targets α8 nAChR.
    Formula:C7H14N4O3
    Colore e forma:Solid
    Peso molecolare:202.21
  • (rel)-Asperparaline A

    CAS:
    <p>Aspergillimide, from A. japonicus, inhibits silkworm neuron nAChRs (IC50s: 20.2/39.6 nM), not affecting chicken nAChRs, and paralyzes silkworm larvae.</p>
    Formula:C20H29N3O3
    Colore e forma:Solid
    Peso molecolare:359.47
  • (±)-Coniine

    CAS:
    (±)-Coniine, a piperidine alkaloid, is a toxin found in poison hemlock.
    Formula:C8H17N
    Colore e forma:Solid
    Peso molecolare:127.23
  • α-Conotoxin PIA TFA


    α-Conotoxin PIA TFA, targeting nicotinic acetylcholine receptor (nAChR) subtypes with α6 and α3 subunits, acts as an antagonist.
    Formula:C81H126F3N27O27S4
    Purezza:98.81%
    Colore e forma:Solid
    Peso molecolare:2095.3
  • (Rac)-Sabcomeline

    CAS:
    (Rac)-Sabcomeline ((Rac)-SB-202026) is an M1/M4 muscarinic agonist used in the study of neurologic disorders such as schizophrenia.
    Formula:C10H15N3O
    Purezza:99.14%
    Colore e forma:Solid
    Peso molecolare:193.25
  • NSC 23766

    CAS:
    NSC 23766 is a Rac1 GTPase inhibitor by targeting GEFs, inhibiting cell proliferation.NSC23766 competitively inhibits M2 mAChR-induced Rac1 activation.
    Formula:C24H35N7
    Purezza:99.49%
    Colore e forma:Solid
    Peso molecolare:421.58
  • Tolterodine

    CAS:
    Tolterodine ((R)-(+)-Tolterodine) is an mACh antagonist used in the treatment of detrusor instability and overactive bladder syndrome.
    Formula:C22H31NO
    Purezza:99.71%
    Colore e forma:White Like Or Light Brown Crystalline Powder
    Peso molecolare:325.49
  • Metixene hydrochloride hydrate

    CAS:
    Metixene HCl hydrate is a potential anticholinergic for Parkinson's with IC50 of 55 nM and Ki of 15 nM against muscarine receptors.
    Formula:C20H26ClNOS
    Purezza:99.99%
    Colore e forma:Solid
    Peso molecolare:363.95
  • NKH477

    CAS:
    NKH477 (Colforsin dapropate hydrochloride) is a derivative of forskolin with antidepressant activity.
    Formula:C27H44ClNO8
    Purezza:98% - 98%
    Colore e forma:Solid
    Peso molecolare:546.09
  • Fipexide hydrochloride

    CAS:
    Fipexide (hydrochloride) is a kind of psychoactive drug of the piperazine class.
    Formula:C20H22Cl2N2O4
    Colore e forma:Solid
    Peso molecolare:425.31
  • YM-58790 hydrochloride

    CAS:
    YM-58790 is a potent M3 muscarinic receptor antagonist(Ki of 15 nM).
    Formula:C27H32ClN3O2
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:466.02
  • Palmatine hydroxide

    CAS:
    <p>Palmatine hydroxide: oral IDO-1 inhibitor (IC50: 3-157μM), targets WNV protease, has anti-cancer/viral and neuroprotective properties.</p>
    Formula:C21H23NO5
    Colore e forma:Solid
    Peso molecolare:369.41
  • Cevimeline

    CAS:
    Cevimeline: muscarinic agonist, treats dry mouth & Sjögren's, boosts saliva post-cancer radiotherapy.
    Formula:C10H17NOS
    Colore e forma:Off-White Solid
    Peso molecolare:199.31
  • ABT-107

    CAS:
    ABT-107: α7 neuronal receptor agonist; protects rats' brains from 6-OHDA-induced damage.
    Formula:C19H20N4O
    Colore e forma:Solid
    Peso molecolare:320.396
  • Dexetimide

    CAS:
    Dexetimide, a muscarinic receptor antagonist, treats neuroleptic-induced parkinsonism.
    Formula:C23H26N2O2
    Colore e forma:Solid
    Peso molecolare:362.46
  • β2AR/M-receptor agonist-2

    CAS:
    <p>β2AR/M-receptor agonist-2 is a dual-function compound acting as a muscarinic antagonist and β2 adrenoceptor agonist (MABA).</p>
    Formula:C36H49ClN4O7S
    Colore e forma:Solid
    Peso molecolare:717.31