AChR
Gli inibitori del recettore dell'acetilcolina (AChR) sono composti che bloccano l'attività dei recettori dell'acetilcolina, fondamentali per la neurotrasmissione nei sistemi nervoso centrale e periferico. Gli AChR svolgono un ruolo cruciale nella contrazione muscolare, nella memoria e nelle funzioni cognitive. Gli inibitori degli AChR vengono utilizzati per studiare condizioni come la miastenia grave, l'Alzheimer e altri disturbi neurologici. Modulando l'attività degli AChR, questi inibitori possono aiutare a svelare le complessità della segnalazione colinergica nel cervello. Presso CymitQuimica, offriamo una gamma di inibitori degli AChR per supportare la tua ricerca in neuroscienze, farmacologia e malattie neurodegenerative.
Trovati 619 prodotti di "AChR"
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R-(+)-Cotinine
CAS:<p>R-(+)-Cotinine, an inactive nicotine metabolite, boosts Ach-induced current in human α7 nAChRs.</p>Formula:C10H12N2OColore e forma:SolidPeso molecolare:176.22Hydroxybupropion
CAS:Hydroxybupropion is the major active metabolite of Bupropion and an antagonist of nACh receptor. Hydroxybupropion inhibits norepinephrine uptake (IC50 = 1.7 μM).Formula:C13H18ClNO2Purezza:99.73%Colore e forma:Off-White SolidPeso molecolare:255.74Irsogladine maleate
CAS:Compound PDK0375, with CAS No. 84504-69-8, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0375 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.Formula:C9H7Cl2N5Colore e forma:SolidPeso molecolare:256.09M 8218
CAS:M 8218 is a bioactive chemical.Formula:C20H29NO2Colore e forma:SolidPeso molecolare:315.45Imidafenacin Metabolite M4
CAS:Imidafenacin M4 is a CYP3A4-formed metabolite of the muscarinic antagonist imidafenacin.Formula:C18H19N3O3Colore e forma:SolidPeso molecolare:325.368Epiboxidine
CAS:Epiboxidine: Potent, selective nAChR agonist; Ki 0.46/1.2 nM for rat/human α4β2; analogous to Epibatidine and ABT 418.Formula:C10H14N2OColore e forma:SolidPeso molecolare:178.23Migrastatin
CAS:Migrastatin is a bacterial metabolite that has been found inStreptomyceswith antimuscarinic and anticancer activities.1,2It binds to M1-5muscarinicFormula:C27H39NO7Colore e forma:SolidPeso molecolare:489.6093-hydroxy Darifenacin
CAS:3-hydroxy Darifenacin, darifenacin metabolite, blocks M1-5 muscarinic receptors with varying potency (Kis: 2.24-79.43 nM) in CHO cells.Formula:C28H30N2O3Colore e forma:SolidPeso molecolare:442.559bPiDDB
CAS:<p>bPiDDB (N,N'-Dodecylbis-Picolinium Bromide) is a nicotinic receptor (nAChR) antagonist.</p>Formula:C24H38Br2N2Purezza:98.72%Colore e forma:SolidPeso molecolare:514.38Epiboxidine hydrochloride
CAS:Epiboxidine HCl: potent α4β2 nAChR agonist; Ki 0.46 nM (rat), 1.2 nM (human); Epibatidine analog.Formula:C10H15ClN2OColore e forma:SolidPeso molecolare:214.695-AMAM-2-CP
CAS:5-AMAM-2-CP, a significant metabolite of Acetamiprid, serves as a global insecticide within the neonicotinoid class and acts as an nAChR agonist [1] [2].Formula:C9H11ClN2OColore e forma:SolidPeso molecolare:198.65Anabaseine
CAS:Anabaseine is a broad nicotinic agonist, favoring alpha-7 AChRs in muscle/brain, and weakly stimulates alpha-4 beta-2 nAChRs.Formula:C10H12N2Colore e forma:SolidPeso molecolare:160.22trans-Cevimeline hydrochloride
CAS:<p>AF 102A hydrochloride is a biochemical.</p>Formula:C10H18ClNOSColore e forma:SolidPeso molecolare:235.77PDE4-IN-4
CAS:PDE4-IN-4 is a compound acting as both a potent M3 antagonist (p IC 50 = 10.2) and a PDE4 inhibitor (p IC 50 = 8.8), designed for inhalation-based treatment ofFormula:C36H37Cl2N3O7SColore e forma:SolidPeso molecolare:726.67PF-06827443
PF-06827443 is a orally bioavailable, CNS-penetrant M1-selective PAM with minimal agonist activity.Formula:C24H24N2O4Colore e forma:SolidPeso molecolare:404.47nAChR agonist CMPI hydrochloride
CAS:CMPI hydrochloride: Potent α4:α4 nAChR PAM; EC50 0.26 μM for (α4)3(β2)2 response to ACh; may aid nicotine dependence, neuropsychiatric research.Formula:C18H20Cl2N4OColore e forma:SolidPeso molecolare:379.29MK-0969
CAS:MK-0969 (J-104135) is a possible M3 antagonist for the treatment of chronic obstructive pulmonary disease.Formula:C24H30F2N4O2Colore e forma:SolidPeso molecolare:444.52Mant-GTPγS
CAS:<p>Mant-GTPγS, an effective GTP analog, displays strong competitive inhibition of adenylyl cyclase (AC). Additionally, it acts as a potent inhibitor of YdeH.</p>Formula:C18H23N6O14P3SColore e forma:SolidPeso molecolare:672.39ANQ-9040
CAS:ANQ-9040 is a nondepolarizing neuromuscular relaxant of the steroid class.Formula:C36H58N2O5SColore e forma:SolidPeso molecolare:630.92Guanylyl Imidodiphosphate (lithium salt)
CAS:Guanylyl Imidodiphosphate (lithium salt) is a non-hydrolyzable GTP analog that increases adenylate cyclase activity.Formula:C10H13Li4N6O13P3Colore e forma:SolidPeso molecolare:545.93
