AChR
Gli inibitori del recettore dell'acetilcolina (AChR) sono composti che bloccano l'attività dei recettori dell'acetilcolina, fondamentali per la neurotrasmissione nei sistemi nervoso centrale e periferico. Gli AChR svolgono un ruolo cruciale nella contrazione muscolare, nella memoria e nelle funzioni cognitive. Gli inibitori degli AChR vengono utilizzati per studiare condizioni come la miastenia grave, l'Alzheimer e altri disturbi neurologici. Modulando l'attività degli AChR, questi inibitori possono aiutare a svelare le complessità della segnalazione colinergica nel cervello. Presso CymitQuimica, offriamo una gamma di inibitori degli AChR per supportare la tua ricerca in neuroscienze, farmacologia e malattie neurodegenerative.
Trovati 618 prodotti di "AChR"
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Epibatidine 2HCl
CAS:Epibatidine 2HCl is a potent nicotinic agonist.Formula:C11H15Cl3N2Purezza:98%Colore e forma:SolidPeso molecolare:281.61Flutropium Bromide
CAS:Flutropium Bromide is a competitive antagonist of acetylcholine. It is used to treat asthma and chronic obstructive pulmonary.Formula:C24H29BrFNO3Purezza:98%Colore e forma:SolidPeso molecolare:478.39Vesamicol
CAS:Vesamicol is an experimental drug. It acting presynaptically by inhibiting acetylcholine uptake into synaptic vesicles and reducing its release.Formula:C17H25NOPurezza:98%Colore e forma:SolidPeso molecolare:259.39Siltenzepine
CAS:Siltenzepine is an agent of anti-acid agent,and used in the treatment of peptic ulcers.Formula:C19H20ClN3O4Purezza:98%Colore e forma:SolidPeso molecolare:389.83L 858051
CAS:L 858051 activates adenylate cyclase. It also inhibits glucose transport in rat adipocytes.Formula:C29H48N2O7Colore e forma:SolidPeso molecolare:536.7S16961
CAS:S16961 (S169611) is an agonist of nicotinic receptor.Formula:C41H71NO6Purezza:99.69%Colore e forma:SolidPeso molecolare:674.01DBO-83
CAS:DBO-83, an agonist of nicotinic acetylcholine receptors (nAChRs), has anti-amnesic and antinociceptive activities.Formula:C10H15Cl3N4Purezza:98%Colore e forma:SolidPeso molecolare:297.61ADX-10061
CAS:ADX-10061 is a dopamine D1 receptor antagonist.Formula:C19H20N2O4Colore e forma:SolidPeso molecolare:340.37JN403
CAS:<p>JN403 is a selective agonist of nicotinic acetylcholine receptor alpha7.</p>Formula:C16H21FN2O2Colore e forma:SolidPeso molecolare:292.35Afacifenacin
CAS:Afacifenacin (SMP-986) fumarate is an M3-selective antagonist for ischemic heart disease and urinary disorders.Formula:C27H26F3N3O2Purezza:99.83%Colore e forma:SolidPeso molecolare:481.51Tebanicline tosylate
CAS:Tebanicline: synthetic, potent, non-opioid analgesic, less toxic than epibatidine; relieves neuropathic pain, acts on α3β4 and α4β2 nicotinic receptors.Formula:C16H19ClN2O4SPurezza:98%Colore e forma:SolidPeso molecolare:370.85Tarafenacin D-tartrate
CAS:Tarafenacin D-tartrate is a highly selective M3 muscarinic receptor antagonist (Ki= 0.19 nM), ~200 fold selectivity over the M2 receptor.Formula:C25H26F4N2O8Purezza:99.86%Colore e forma:SolidPeso molecolare:558.48Terodiline hydrochloride
CAS:<p>Terodiline hydrochloride is an antagonist of M1-selective muscarinic receptor (mAChR)(Kbs of 15, 160, 280, and 198 nM in rabbit vas deferens (M1), atria (M2),</p>Formula:C20H28ClNPurezza:98%Colore e forma:SolidPeso molecolare:317.9YM-46303
CAS:YM-46303 is a selective and potent muscarinic receptor antagonist that exhibits high affinity for the M3 receptor.YM-46303 can be used to study bradycardia inFormula:C20H23ClN2O2Purezza:>99.99%Colore e forma:SolidPeso molecolare:358.86CHF5407
CAS:CHF5407（SVT-47060） is a potent and selective muscarinic M3 receptor antagonist with prolonged action at muscarinic receptors.CHF5407 has an effect onFormula:C27H25BrF4N2O3SPurezza:99.54% - >99.99%Colore e forma:SolidPeso molecolare:613.46UP202-56
CAS:UP202-56 is an adenosinergic agonist and is an adenosine analog.Formula:C33H37N7O4Purezza:98%Colore e forma:SolidPeso molecolare:595.69CB-7921220
CAS:<p>CB-7921220 (6-[2-(4-Aminophenyl)vinyl]-2-pyridinecarboxylic acid) is an inhibitor of adenylate cyclase.</p>Formula:C14H12N2O2Purezza:99.59%Colore e forma:SolidPeso molecolare:240.26KL8604166
CAS:KL8604166 (UCB-11056) is a potential puzzle compound.UCB-11056 amplifies the formation of inducible cyclic AMP in rat brain tissue.Formula:C12H21N5O2Purezza:99.21%Colore e forma:SolidPeso molecolare:267.33PF-06767832
CAS:PF-06767832: selective M1 PAM (EC50=60 nM), no M2-M5 activity, good CNS penetration, but has GI and cardiovascular risks.Formula:C22H23N3O3SColore e forma:SolidPeso molecolare:409.5Hadacidin
CAS:Hadacidin is an inhibitor of AMP synthesis. Hadacidin and hadacidin analogues have anticancer activity and activity against adenylosuccinate synthetase.Formula:C3H5NO4Colore e forma:SolidPeso molecolare:119.08Glucagon Receptor Antagonist I
CAS:Glucagon antagonist I blocks the GCGR (IC50=181 nM), stops glucagon-induced glycogenolysis, and lowers glucose in glucagon-treated humanized mice.Formula:C20H30N2OSColore e forma:SolidPeso molecolare:346.53RJR-2429
CAS:RJR-2429 is a potent AChR agonist.Formula:C12H16N2Colore e forma:SolidPeso molecolare:188.27CC4
CAS:Selective α6β2/α4β2 partial agonist; Ki: 12/26nM (rat); poor α3β4/α7 affinity; stimulates dopamine release; reduces nicotine self-admin in rats.Formula:C24H30N4O2Colore e forma:SolidPeso molecolare:406.52Hadacidin sodium
CAS:Hadacidin sodium is an inhibitor of AMP synthesis. Hadacidin and hadacidin analogues have anticancer activity and activity against adenylosuccinate synthetase.Formula:C3H4NNaO4Colore e forma:SolidPeso molecolare:141.06Dexetimide HCl
CAS:Dexetimide HCl is a muscarinic antagonist that has been used to treat neuroleptic-induced parkinsonism. Benzetimide is the (-)-enantimorph of dexetimide.Formula:C23H27ClN2O2Colore e forma:SolidPeso molecolare:398.93(E/Z)-VU0029767
CAS:VU0029767 enhances M1 muscarinic receptor function, increasing acetylcholine potency and efficacy.Formula:C21H21N3O3Colore e forma:SolidPeso molecolare:363.41Octamylamine sulfamate
CAS:Octamylamine sulfamate is a P450 inhibitor.Formula:C13H32N2O3SColore e forma:SolidPeso molecolare:296.47Cimetropium Bromide
CAS:Cimetropium Bromide is a mAChR antagonist used for long-term treatment of irritable bowel syndrome.Formula:C21H28BrNO4Colore e forma:SolidPeso molecolare:438.36Metanicotine
CAS:Metanicotine is a selective nicotinic agonist with antinociceptive properties.Formula:C10H14N2Colore e forma:SolidPeso molecolare:162.23Caramiphen hydrochloride
CAS:Caramiphen hydrochloride: antimuscarinic, anticholinergic, NMDA receptor antagonist salt.Formula:C18H28ClNO2Colore e forma:SolidPeso molecolare:325.88TC-1698 dihydrochloride
CAS:TC-1698 dihydrochloride: selective α7 nicotinic agonist, with some β-receptor activity; neuroprotectant.Formula:C13H20Cl2N2Colore e forma:SolidPeso molecolare:275.22Octamylamine hydrochloride
CAS:Octamylamine hydrochloride is a P450 inhibitor.Formula:C13H30ClNColore e forma:SolidPeso molecolare:235.84Neopterin, L-erythro-
CAS:Neopterin, L-erythro- can be used as a cholinergic receptor.Formula:C9H11N5O4Colore e forma:SolidPeso molecolare:253.21Methacholine iodide
CAS:Methacholine iodide is a muscarinic acetylcholine receptor agonist.Formula:C8H18INO2Colore e forma:SolidPeso molecolare:287.14GP531
CAS:GP531, a second-gen adenosine regulator, is inactive at rest but boosts adenosine in ischemia.Formula:C16H21N5O4Colore e forma:SolidPeso molecolare:347.37Meseclazone
CAS:<p>Meseclazone has anti-inflammatory, analgesic, and antipyretic activity. Meseclazone shows inhibitory potency of secondary phase ADP aggregation.</p>Formula:C11H10ClNO3Purezza:98%Colore e forma:SolidPeso molecolare:239.65AQ-RA 721
CAS:AQ-RA 721 is a selective muscarinic antagonist with high affinity for M1- and M3-receptors. AQ-RA 721 may be used as a bronchodilator.Formula:C22H23N3O2Colore e forma:SolidPeso molecolare:361.44AZD-9164 bromide
CAS:AMG-221, a selective 11β-HSD1 inhibitor, suppresses enzyme activity, lowers glucose/insulin, and reduces weight in obese mice.Formula:C29H38BrFN2O2Colore e forma:SolidPeso molecolare:545.53UH-AH 37
CAS:UH-AH 37 is a antagonist of human muscarinic acetylcholine receptor.Formula:C21H23Cl2N3O2Purezza:98%Colore e forma:SolidPeso molecolare:420.33DAU 5884 HCl
CAS:DAU 5884 HCl is an M3 receptor antagonistFormula:C17H21N3O3Colore e forma:SolidPeso molecolare:315.37Ethybenztropine HBr
CAS:Ethybenztropine HBr is an anticholinergic which is used as an antiparkinsonian agent. Ethybenztropine may also act as a dopamine reuptake inhibitor.Formula:C22H28BrNOColore e forma:SolidPeso molecolare:402.37Atropine Oxide Hydrochloride
CAS:Atropine Oxide, a derivative of anticholinergic Atropine, treats poisonings, slow heart rate, and reduces saliva during surgery.Formula:C17H24ClNO4Colore e forma:SolidPeso molecolare:341.83YM-58790
CAS:YM-58790 is a potent mAChR blocker with Ki values of 28 nM (M1), 260 nM (M2), 15 nM (M3), and reduces bladder contractions in rats.Formula:C27H31N3O2Purezza:99.87%Colore e forma:SoildPeso molecolare:429.55UB 165 fumarate
CAS:<p>UB 165 fumarate is a nAChR agonist, α4β2 partial, α3β2 full, with a 0.27 nM Ki for [3H]-nicotine in rat brain.</p>Formula:C17H19ClN2O4Purezza:99.72%Colore e forma:SolidPeso molecolare:350.8Metixene hydrochloride
CAS:Metixene hydrochloride is an anticholinergic antiparkinsonian agent.Formula:C20H24ClNSPurezza:98%Colore e forma:SolidPeso molecolare:345.93CP-601932
CAS:CP-601932 (free base) is a selective base α( 4) β( 2) Nicotinic acetylcholine receptor agonist.Formula:C12H12F3NColore e forma:SolidPeso molecolare:227.23CDD0102
CAS:CDD0102 is a potent agonist of M1 Muscarinic receptor.Formula:C8H12N4OPurezza:98%Colore e forma:SolidPeso molecolare:180.215-Iodo-A-85380 dihydrochloride
CAS:α4β2 and α6β2 nicotinic acetylcholine receptors agonistFormula:C9H13Cl2IN2OPurezza:98%Colore e forma:SolidPeso molecolare:363.02Dimethyl-W84 (dibromide)
CAS:Dimethyl-W84, selective M2 muscarinic receptor modulator; slows N-methylscopolamine release, EC50=3 nM.Formula:C34H48Br2N4O4Colore e forma:SolidPeso molecolare:736.59LY 2087101
CAS:Allosteric potentiator of α7, α4β2 and α4β4 nAChRsFormula:C15H11FN2OS2Purezza:98%Colore e forma:SolidPeso molecolare:318.39
