AChR
Gli inibitori del recettore dell'acetilcolina (AChR) sono composti che bloccano l'attività dei recettori dell'acetilcolina, fondamentali per la neurotrasmissione nei sistemi nervoso centrale e periferico. Gli AChR svolgono un ruolo cruciale nella contrazione muscolare, nella memoria e nelle funzioni cognitive. Gli inibitori degli AChR vengono utilizzati per studiare condizioni come la miastenia grave, l'Alzheimer e altri disturbi neurologici. Modulando l'attività degli AChR, questi inibitori possono aiutare a svelare le complessità della segnalazione colinergica nel cervello. Presso CymitQuimica, offriamo una gamma di inibitori degli AChR per supportare la tua ricerca in neuroscienze, farmacologia e malattie neurodegenerative.
Trovati 618 prodotti di "AChR"
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Ethybenztropine HCl
CAS:Ethybenztropine HCl is an anticholinergic which is used as an antiparkinsonian agent. Ethybenztropine may also act as a dopamine reuptake inhibitor.Formula:C22H28ClNOColore e forma:SolidPeso molecolare:357.92Esoxybutynin Chloride
CAS:(S)-oxybutynin, with antimuscarinic effects, is being developed for urinary incontinence.Formula:C22H32ClNO3Colore e forma:SolidPeso molecolare:393.95AR-R 17779 hydrochloride
CAS:AR-R17779 hydrochloride: potent α7 nAChR agonist; K i : 92 nM (α7), 16,000 nM (α4β2); enhances rat cognition; anxiolytic; anti-inflammatory.Formula:C9H15ClN2O2Colore e forma:SolidPeso molecolare:218.68Elucaine
CAS:Elucaine is an antagonist of the muscarinic acetylcholine receptor. It has anti-ulcerative activity.Formula:C19H23NO2Purezza:98%Colore e forma:SolidPeso molecolare:297.39(R,R)-Glycopyrrolate
CAS:(R,R)-Glycopyrrolate is an agent of anticholinergic, has the ability to reduce the frequency of drooling in vivo with developmental disabilities.Formula:C19H28BrNO3Purezza:98%Colore e forma:SolidPeso molecolare:398.34SIB 1508Y maleate
CAS:neuronal nicotinic ACh receptor agonistFormula:C16H18N2O4Purezza:98%Colore e forma:SolidPeso molecolare:302.33LRE1
CAS:<p>LRE1 is a specific and allosteric soluble adenylyl cyclase inhibitor.</p>Formula:C12H13ClN4SPurezza:>99.99%Colore e forma:SolidPeso molecolare:280.78Terodiline
CAS:Terodiline is an orally available selective muscarinic M1 receptor and calcium channel antagonist for the study of diseases caused by abnormal bladder function.Formula:C20H27NPurezza:98.20% - 99.59%Colore e forma:SolidPeso molecolare:281.44Methacholine bromide
CAS:Methacholine bromide is a potent M3 agonist for diagnosing asthma by identifying bronchial hyperresponsiveness.Formula:C8H18BrNO2Colore e forma:SolidPeso molecolare:240.141Nuvenzepine
CAS:Nuvenzepine is an antagonist of mAChR. It has the potential for gastrospasm treatment.Formula:C19H20N4O2Purezza:98%Colore e forma:SolidPeso molecolare:336.39DA 4626
CAS:DA 4626 is an H2-receptor antagonist with KB values akin to those in standard assays.Formula:C14H18N4Purezza:98%Colore e forma:SolidPeso molecolare:242.32PQCA
CAS:<p>PQCA is a selective M1 receptor modulator with EC50s of 49 nM (monkey) and 135 nM (human), potential for Alzheimer's treatment.</p>Formula:C22H20N4O3Purezza:99.88%Colore e forma:SolidPeso molecolare:388.42Telenzepine
CAS:Telenzepine is a potent and selective M1 antimuscarinic.Formula:C19H22N4O2SPurezza:98%Colore e forma:SolidPeso molecolare:370.47AC260584
CAS:AC260584 is an M1 muscarinic receptor allosteric agonist (pEC50: 7.6).Formula:C20H29FN2O2Colore e forma:SolidPeso molecolare:348.45Neramexane Mesylate
CAS:<p>Neramexane: NMDA & nicotinic receptor blocker with neuroprotective, antidepressant, and cognitive-enhancing effects.</p>Formula:C12H27NO3SPurezza:98%Colore e forma:SolidPeso molecolare:265.41ML381
CAS:ML381 is a M5-orthosteric antagonist with a high selectivity of muscarinic subtype.Formula:C21H21N3O4Colore e forma:SolidPeso molecolare:379.41ML169
CAS:ML169 is a selective and brain penetrant M1 positive allosteric modulator (PAM).Formula:C21H17BrFN3O4SPurezza:98%Colore e forma:SolidPeso molecolare:506.34Zamifenacin
CAS:Zamifenacin obviously decreases colonic motility in irritable bowel syndrome. Zamifenacin is an effective gut-selective muscarinic M3 receptor antagonist.Formula:C27H29NO3Purezza:98%Colore e forma:SolidPeso molecolare:415.52BNC375
CAS:BNC375 is a α7 nAChRs type I positive allosteric modulator (EC50: 1.9 μM).Formula:C19H23ClN2O3SPurezza:98%Colore e forma:SolidPeso molecolare:394.92(R,R)-Reboxetine mesylate
CAS:(R,R)-Reboxetine mesylate: Antidepressant, high bioavailability, (R,R) enantiomer, selective for noradrenaline, low toxicity.Formula:C20H27NO6SColore e forma:SolidPeso molecolare:409.5M1 ligand 1
CAS:Compound 3b-b: N-desmethyl arecoline derivative, muscarinic M1 ligand, potential PET radiotracer.Formula:C20H21NO2Colore e forma:SolidPeso molecolare:307.39Benzatropine
CAS:Benzatropine: Central muscarinic blocker, inhibits dopamine uptake, treats Parkinson's symptoms.Formula:C21H25NOPurezza:98%Colore e forma:SolidPeso molecolare:307.43Muscarine iodide
CAS:Muscarinic acetylcholine receptor agonistFormula:C9H20INO2Purezza:98%Colore e forma:SolidPeso molecolare:301.17Penehyclidine hydrochloride
CAS:<p>Penehyclidine hydrochloride: M1/M3 antagonist, activates NF-κB, anti-inflammatory, anticholinergic.</p>Formula:C20H30ClNO2Purezza:99.79%Colore e forma:SolidPeso molecolare:351.91Tridihexethyl chloride
CAS:Tridihexethyl is an anticholinergic, antimuscarinic, and antispasmolytic drug, which can be used to treat acquired nystagmus or peptic ulcer disease.Formula:C21H36ClNOColore e forma:SolidPeso molecolare:353.97TC 2559 difumarate
CAS:partial agonist of α4β2 nicotinic acetylcholine receptorFormula:C12H18N2OC4H404Purezza:98%Colore e forma:SolidPeso molecolare:380.39TC299423
CAS:TC299423 is a novel agonist for nicotinic acetylcholine receptors (nAChRs). TC299423 modestly selectively targets α6β2 subtype.Formula:C11H15N3Colore e forma:SolidPeso molecolare:189.26SM-21 maleate
CAS:Increases release of acetylcholine,σ2 antagonistFormula:C22H28ClNO7Purezza:98%Colore e forma:SolidPeso molecolare:453.91TC 1698 dihydrochloride
CAS:nicotinic α7 receptor agonistFormula:C13H18N2Purezza:98%Colore e forma:SolidPeso molecolare:202.3Beperidium iodide
CAS:Beperidium iodide is a competitive antagonist of the acetylcholine receptor (pA2: 7.93).Formula:C23H34IN3O3Colore e forma:SolidPeso molecolare:527.44WIN 62,577
CAS:WIN 62,577 is a allosteric antagonist of mAChR.Formula:C29H31N3OPurezza:98%Colore e forma:SolidPeso molecolare:437.58Sulfoxaflor
CAS:Sulfoxaflor (GF 2032) is an agonist of nAChR1 and nAChR2 subtypes and a systemic insecticide. Cost-effective and quality-assured.Formula:C10H10F3N3OSPurezza:99.56%Colore e forma:SolidPeso molecolare:277.27Benzamide Derivative 1
CAS:Benzamide Derivative 1 Benzamide derivative with gastrokinetic activity.Benzamide Derivative 1 can be used in the study of gastrointestinal diseases.Formula:C22H34ClN3O3Purezza:>99.99%Colore e forma:SolidPeso molecolare:423.98Alvameline
CAS:Alvameline (Lu25-109) is a partial M1 agonist. Alvameline (Lu25-109) also is a M2/M3 antagonist.Formula:C9H15N5Purezza:98%Colore e forma:SolidPeso molecolare:193.25Muscarine chloride
CAS:Muscarine chloride is a toxic alkaloid found in Amanita muscaria and other fungi of the Inocybe species.Formula:C9H20ClNO2Colore e forma:SolidPeso molecolare:209.71Quifenadine
CAS:Quifenadine, an H1-histamine receptor blocker, has antiarrhythmic properties.Formula:C20H23NOPurezza:98%Colore e forma:SolidPeso molecolare:293.4DAU 5884 hydrochloride
CAS:muscarinic M3 receptor antagonistFormula:C17H22ClN3O3Purezza:98%Colore e forma:SolidPeso molecolare:351.83Nelonicline
CAS:Nelonicline is a selective agonist of neuronal nicotinic receptors.Formula:C17H19N3OSPurezza:98%Colore e forma:SolidPeso molecolare:313.42SIB-1553A hydrochloride
CAS:SIB-1553A hydrochloride is a nicotinic acetylcholine receptor agonist and a selective neuronal nAChR ligandFormula:C13H20ClNOSPurezza:99.56% - 99.73%Colore e forma:SolidPeso molecolare:273.82BTM-1086
CAS:BTM-1086 is a potent gastric secretory inhibitor and an anti-ulcer agent.Formula:C21H25N3OSPurezza:98%Colore e forma:SolidPeso molecolare:367.51GSK233705
CAS:GSK233705, a muscarinic antagonist, is used to prevent/treat COPD and asthma.Formula:C24H29BrN2Purezza:99.87% - 99.98%Colore e forma:SolidPeso molecolare:425.4SCH-900271
CAS:SCH-900271 treats dyslipidemia by targeting nicotinic acid receptors, addressing hyperlipidaemia.Formula:C14H16N2O4Purezza:98.82% - 99.93%Colore e forma:SolidPeso molecolare:276.29Xanomeline oxalate
CAS:Xanomeline oxalate (LY246708), a potent SMRA, boosts phosphoinositide hydrolysis; key for Alzheimer's research.Formula:C16H25N3O5SPurezza:99.1%Colore e forma:SolidPeso molecolare:371.45Posatirelin
CAS:Posatirelin, a synthetic peptide, modulates and nourishes brain systems, aiding in vascular dementia research.Formula:C17H28N4O4Purezza:99.43% - 99.95%Colore e forma:SolidPeso molecolare:352.43CP-810123
CAS:CP-810123 is an α7 nAChR agonist used to treat cognitive deficits associated with psychiatric or neurological disorders such as schizophrenia.Formula:C14H18N4OPurezza:98.63% - 99.60%Colore e forma:SolidPeso molecolare:258.32Desformylflustrabromine hydrochloride
CAS:Desformylflustrabromine hydrochloride (dFBr hydrochloride) is a selective agonist of nicotinic acetylcholine receptor (nAChR) in α4β2 neurons, with pEC50 of 6.Formula:C17H12INO5Purezza:99.79%Colore e forma:SolidPeso molecolare:437.19PF-03635659
CAS:PF-03635659: potent M3 antagonist, Ki=0.2 nM, long half-life, potential COPD treatment.Formula:C28H32N2O3Purezza:98.39% - 99.85%Colore e forma:SolidPeso molecolare:444.57Thonzylamine hydrochloride
CAS:Thonzylamine hydrochloride (Resistab) is an anticholinergic and antihistamine used as an antipruritic.Formula:C16H23ClN4OPurezza:99.67%Colore e forma:White Crystalline PowderPeso molecolare:322.83NKY80
CAS:NKY80 regulates the adenylyl cyclase catalytic activity in heart and lung tissues.Formula:C12H11N3O2Purezza:99.88%Colore e forma:SolidPeso molecolare:229.23Xanomeline
CAS:<p>Xanomeline: orally active, M1/M4 selective activator for neurological disorders; promising in trials, crosses blood-brain barrier, liver metabolized.</p>Formula:C14H23N3OSPurezza:99.61%Colore e forma:SolidPeso molecolare:281.42
