AChR
Gli inibitori del recettore dell'acetilcolina (AChR) sono composti che bloccano l'attività dei recettori dell'acetilcolina, fondamentali per la neurotrasmissione nei sistemi nervoso centrale e periferico. Gli AChR svolgono un ruolo cruciale nella contrazione muscolare, nella memoria e nelle funzioni cognitive. Gli inibitori degli AChR vengono utilizzati per studiare condizioni come la miastenia grave, l'Alzheimer e altri disturbi neurologici. Modulando l'attività degli AChR, questi inibitori possono aiutare a svelare le complessità della segnalazione colinergica nel cervello. Presso CymitQuimica, offriamo una gamma di inibitori degli AChR per supportare la tua ricerca in neuroscienze, farmacologia e malattie neurodegenerative.
Trovati 617 prodotti di "AChR"
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Deschloroclozapine
CAS:Deschloroclozapine, a metabolite of Clozapine, is a highly potent muscarinic DREADDs agonist.Formula:C18H20N4Purezza:99.61% - 99.98%Colore e forma:SolidPeso molecolare:292.38Benactyzine hydrochloride
CAS:<p>Benactyzine hydrochloride (Neuroleptone) is a centrally acting muscarinic antagonist.</p>Formula:C20H26ClNO3Purezza:99.03% - 99.94%Colore e forma:SolidPeso molecolare:363.88Fipexide
CAS:Fipexide (Attentil, Vigilor), a psychoactive drug of the piperazine chemical class, was developed in Italy in 1983.Formula:C20H21ClN2O4Purezza:97.6% - 99.95%Colore e forma:SolidPeso molecolare:388.842',5'-Dideoxyadenosine
CAS:2',5'-Dideoxyadenosine is a potent and non-competitive adenylyl cyclase inhibitor via binding the P-site (IC50: 3 μM).Formula:C10H13N5O2Purezza:99.55%Colore e forma:White SolidPeso molecolare:235.24DL-trihexyphenidyl hydrochloride
CAS:DL-trihexyphenidyl hydrochloride (Trihexyphenidyl HCl) is a muscarinic antagonist.Formula:C20H32ClNOPurezza:99.63% - 99.71%Colore e forma:SolidPeso molecolare:337.93Pyrantel pamoate
CAS:<p>Pyrantel pamoate (Pyrantel embonate) is a depolarizing neuromuscular blocking agent.</p>Formula:C34H30N2O6SPurezza:99.71%Peso molecolare:594.69(Rac)-ABT-202 dihydrochloride
CAS:(Rac)-ABT-202 dihydrochloride is a racemate of ABT-202. ABT-202 is an nicotinic acetylcholine receptors (nAChRs) agonist and can be used as an analgesic.Formula:C9H15Cl2N3Purezza:97.4%Colore e forma:SolidPeso molecolare:236.142Primidone
CAS:Primidone (NCI-C56360) is a potent anticonvulsant agent.Formula:C12H14N2O2Purezza:99.91%Colore e forma:Crystals (Ntp 1992)Peso molecolare:218.25Nebracetam hydrochloride
CAS:Nebracetam HCl (WEB 1881 FU) is an M1-muscarinic agonist nootropic, increasing intracellular Ca2+ with an EC50 of 1.59 mM.Formula:C12H17ClN2OPurezza:99.23%Colore e forma:SolidPeso molecolare:240.729Pyrantel tartrate
CAS:Pyrantel tartrate (Banminth) is broad spectrum anthelmintic for livestock.Formula:C15H20N2O6SPurezza:99.96%Colore e forma:White CrystalsPeso molecolare:356.39(Rac)-Sabcomeline HCl
CAS:<p>Sabcomeline HCl is an M1 receptor agonist that can be used to study Alzheimer's disease.</p>Formula:C10H16ClN3OPurezza:99.58%Colore e forma:SoildPeso molecolare:229.71Carbachol
CAS:<p>Carbachol (Carbamoylcholine chloride), an analog of acetylcholine, serves as a valuable tool in the investigation of various physiological responses mediated by nicotinic (nAChR) and muscarinic (mAChR) acetylcholine receptors. These responses include smooth muscle contraction, gut motility, and neuronal signaling. Known for its agonistic properties, Carbachol activates both nAChR and mAChR, with reported Ki values ranging from 10 to 10,000 nM for different receptor types and experimental preparations.</p>Formula:C6H15ClN2O2Purezza:>99.99%Colore e forma:SolidPeso molecolare:182.65TAK-071
CAS:<p>TAK-071 is a potent, novel and highly selective modulator of muscarinic acetylcholine receptor 1 (M1R) positive allosteric(EC50 : 520 nM).</p>Formula:C24H24FN3O3Purezza:98.02%Colore e forma:SolidPeso molecolare:421.46Acetamiprid
CAS:Acetamiprid: nAChR agonist, global neonicotinoid insecticide linked to neuromuscular/reproductive issues.Formula:C10H11ClN4Purezza:99.66%Colore e forma:White PowderPeso molecolare:222.67Rocuronium bromide
CAS:Rocuronium bromide (ORG 9426) is a muscle relaxant or aminosteroid non-depolarizing neuromuscular blocker, which is used to provide skeletal muscle relaxation.Formula:C32H53BrN2O4Purezza:99.77% - >99.99%Colore e forma:White Or Off-White PowderPeso molecolare:609.68β2AR/M-receptor agonist-1
CAS:β2AR/M-receptor agonist-1 (example 131), a muscarinic antagonist and β2 adrenoceptor agonist (MABA), exhibits dual potency towards β2 adrenoceptor andFormula:C43H56BrN3O7Colore e forma:SolidPeso molecolare:806.82Methylatropine (nitrate)
CAS:Methylatropine: Muscarinic antagonist, <0.1 nM IC50, atropine derivative, lowers ACh's effect on BP, affects salivation, pupil dilation, heart rate.Formula:C18H26N2O6Colore e forma:SolidPeso molecolare:366.414Lupanine hydrochloride
CAS:Lupanine hydrochloride, a Sparteine derivative, binds to nAChR with a Ki of 500 nM and has ganglioplegic properties.Formula:C15H25ClN2OColore e forma:SolidPeso molecolare:284.83nAChR modulator-1
CAS:nAChR modulator-1, a insecticide, is a insect nAChR orthosteric modulator [1] .Formula:C12H8ClN3O2Colore e forma:SolidPeso molecolare:261.66Navafenterol saccharinate
CAS:AZD-8871 saccharinate is a dual-acting bronchodilator which may be useful in the treatment of Chronic Obstructive Pulmonary Disease (COPD).Formula:C45H47N7O9S3Colore e forma:SolidPeso molecolare:926.09Epiboxidine
CAS:Epiboxidine: Potent, selective nAChR agonist; Ki 0.46/1.2 nM for rat/human α4β2; analogous to Epibatidine and ABT 418.Formula:C10H14N2OColore e forma:SolidPeso molecolare:178.23Lobeline sulfate
CAS:Lobeline sulfate, an alkaloid like nicotine, aids in smoking cessation, insomnia, and respiratory issues. Less potent on nicotinic receptors.Formula:C22H29NO6SPurezza:98%Colore e forma:White PowderPeso molecolare:435.54trans-Cevimeline hydrochloride
CAS:<p>AF 102A hydrochloride is a biochemical.</p>Formula:C10H18ClNOSColore e forma:SolidPeso molecolare:235.77TC-2559 difumarate
CAS:TC-2559 difumarate: Oral α4β2 nAChR partial agonist, CNS-selective, EC50 0.18 μM, prefers α4β2 over α2β4/α4β4/α3β4, antinociceptive.Formula:C20H26N2O9Colore e forma:SolidPeso molecolare:438.43Perindoprilat
CAS:Perindoprilat (Perindoprilate) is an angiotensin-converting enzyme inhibitor.Formula:C17H28N2O5Purezza:99.48%Colore e forma:SolidPeso molecolare:340.41Dicloromezotiaz
CAS:Dicloromezotiaz: Potent insecticide targeting nAChRs, controls various lepidoptera.Formula:C19H12Cl3N3O2SColore e forma:SolidPeso molecolare:452.74Muscarine
CAS:Muscarine is a toxic alkaloid found in Amanita muscaria and other fungi of the Inocybe species.Formula:C9H20NO2Purezza:98%Colore e forma:SolidPeso molecolare:174.26(R)-Dinotefuran
CAS:(R)-Dinotefuran, a neonicotinoid, is 1.7-2.4x more effective against pests like Aphis gossypii and safer for bees.Formula:C7H14N4O3Colore e forma:SolidPeso molecolare:202.21(Rac)-5-Hydroxymethyl Tolterodine hydrochloride
CAS:<p>(Rac)-5-Hydroxymethyl Tolterodine HCl, or (Rac)-Desfesoterodine HCl, is a potent mAChR blocker researched for overactive bladder.</p>Formula:C22H32ClNO2Colore e forma:SolidPeso molecolare:377.95(rel)-Asperparaline A
CAS:<p>Aspergillimide, from A. japonicus, inhibits silkworm neuron nAChRs (IC50s: 20.2/39.6 nM), not affecting chicken nAChRs, and paralyzes silkworm larvae.</p>Formula:C20H29N3O3Colore e forma:SolidPeso molecolare:359.47DSPE-PEG1000-RVG29
DSPE-PEG1000-RVG29 is a PEG compound composed of DSPE and rabies virus glycoprotein 29 (RVG29). RVG29 can specifically bind to nicotinic acetylcholine receptors (nAChR) at the blood-brain barrier (BBB) and cross the BBB.Colore e forma:Odour SolidTMPH
CAS:TMPH is an inhibitor of nAChR and inhibits nAChRs lacking α5, α6, or β3 subunits. TMPH can be used in studies about nAChR dysfunction or neurological disorders.Formula:C16H31NO2Purezza:99.78%Colore e forma:SoildPeso molecolare:269.428-Aminoadenine
CAS:<p>8-Aminoadenine (7H-purine-6,8-diamine) is a ligand for Adenine Receptor with Ki of 0.0341 μM.</p>Formula:C5H6N6Purezza:99.82%Colore e forma:SolidPeso molecolare:150.14M3/PDE4 modulator-1
M3/PDE4 Modulator-1 (compound 10f) serves as a bifunctional entity functioning both as an M3 mAChR antagonist and a PDE4 inhibitor.Formula:C38H41Cl2N3O8SColore e forma:SolidPeso molecolare:770.72Doxacurium Chloride
CAS:Doxacurium Chloride is a muscarinic acetylcholine receptor M2 antagonist.Formula:C56H78ClN2O16Purezza:98%Colore e forma:SolidPeso molecolare:1070.69nAChR modulator-2
CAS:nAChR modulator-2, a insecticide, is a insect nAChR orthosteric modulator [1] .Formula:C12H8ClN3O2Colore e forma:SolidPeso molecolare:261.66nAChR agonist CMPI hydrochloride
CAS:CMPI hydrochloride: Potent α4:α4 nAChR PAM; EC50 0.26 μM for (α4)3(β2)2 response to ACh; may aid nicotine dependence, neuropsychiatric research.Formula:C18H20Cl2N4OColore e forma:SolidPeso molecolare:379.29MK-0969
CAS:MK-0969 (J-104135) is a possible M3 antagonist for the treatment of chronic obstructive pulmonary disease.Formula:C24H30F2N4O2Colore e forma:SolidPeso molecolare:444.52Atracurium
CAS:Atracurium (BW-33A) is a competitive AChR antagonist and non-depolarizing muscle relaxant that may cause bronchoconstriction.Formula:C53H72N2O122Colore e forma:SolidPeso molecolare:929.14α-Conotoxin PIA
CAS:Selective antagonist of α6-containing nicotinic receptors that discriminates between the closely related α6 and α3 subunits (IC50 values are 0.95 and 74.2 nMFormula:C79H125N27O25S4Purezza:98%Colore e forma:SolidPeso molecolare:1981.3α-Conotoxin PIA TFA
α-Conotoxin PIA TFA, targeting nicotinic acetylcholine receptor (nAChR) subtypes with α6 and α3 subunits, acts as an antagonist.Formula:C81H126F3N27O27S4Purezza:98.81%Colore e forma:SolidPeso molecolare:2095.3Epiboxidine hydrochloride
CAS:Epiboxidine HCl: potent α4β2 nAChR agonist; Ki 0.46 nM (rat), 1.2 nM (human); Epibatidine analog.Formula:C10H15ClN2OColore e forma:SolidPeso molecolare:214.69Navafenterol
CAS:AZD-8871, a potential COPD and asthma treatment, may work well with ICS.Formula:C38H42N6O6S2Colore e forma:SolidPeso molecolare:742.91α-Conotoxin AuIB
CAS:Selective antagonist of α3β4 nicotinic acetylcholine receptors.Formula:C65H89N17O21S4Purezza:98%Colore e forma:SolidPeso molecolare:1572.76α-Conotoxin imi
CAS:alpha-Conotoxin imi is a nicotinic acetylcholine receptor ligand.Formula:C52H78N20O15S4Purezza:98%Colore e forma:SolidPeso molecolare:1351.56AC1-IN-1
CAS:<p>AC1-IN-1 is a selective inhibitor of adenylyl cyclase type 1 (AC1, IC50 = 0.54 µM).</p>Formula:C18H18FN5O2Purezza:99.89%Colore e forma:SolidPeso molecolare:355.37Heliosupine N-oxide
Heliosupine N-oxide is a useful organic compound for research related to life sciences and the catalog number is T125058.Formula:C20H31NO8Colore e forma:SolidPeso molecolare:413.467rac-Desethyl Oxybutynin (hydrochloride)
CAS:<p>rac-Desethyl oxybutynin, active oxybutynin metabolite, binds to mAChRs; K_i values 3.12-16 nM; lowers rat micturition pressure.</p>Formula:C20H28ClNO3Colore e forma:SolidPeso molecolare:365.89α-Bungarotoxin
CAS:<p>Neurotoxin that blocks neuromuscular transmission via irreversible inhibition of nicotinic ACh receptors (nAChRs).</p>Formula:C338H529N97O105S11Purezza:98%Colore e forma:SolidPeso molecolare:7984.14DSPE-PEG5000-RVG29
DSPE-PEG5000-RVG29 is a PEG compound comprised of DSPE and rabies virus glycoprotein 29 (RVG29). RVG29 specifically binds to nicotinic acetylcholine receptors (nAChR) at the blood-brain barrier (BBB) and facilitates passage through the BBB.Colore e forma:Odour Solid
