AChR
Gli inibitori del recettore dell'acetilcolina (AChR) sono composti che bloccano l'attività dei recettori dell'acetilcolina, fondamentali per la neurotrasmissione nei sistemi nervoso centrale e periferico. Gli AChR svolgono un ruolo cruciale nella contrazione muscolare, nella memoria e nelle funzioni cognitive. Gli inibitori degli AChR vengono utilizzati per studiare condizioni come la miastenia grave, l'Alzheimer e altri disturbi neurologici. Modulando l'attività degli AChR, questi inibitori possono aiutare a svelare le complessità della segnalazione colinergica nel cervello. Presso CymitQuimica, offriamo una gamma di inibitori degli AChR per supportare la tua ricerca in neuroscienze, farmacologia e malattie neurodegenerative.
Trovati 617 prodotti di "AChR"
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Dicloromezotiaz
CAS:Dicloromezotiaz: Potent insecticide targeting nAChRs, controls various lepidoptera.Formula:C19H12Cl3N3O2SColore e forma:SolidPeso molecolare:452.74α-Conotoxin PIA TFA
α-Conotoxin PIA TFA, targeting nicotinic acetylcholine receptor (nAChR) subtypes with α6 and α3 subunits, acts as an antagonist.Formula:C81H126F3N27O27S4Purezza:98.81%Colore e forma:SolidPeso molecolare:2095.3Atracurium
CAS:Atracurium (BW-33A) is a competitive AChR antagonist and non-depolarizing muscle relaxant that may cause bronchoconstriction.Formula:C53H72N2O122Colore e forma:SolidPeso molecolare:929.14M 8218
CAS:M 8218 is a bioactive chemical.Formula:C20H29NO2Colore e forma:SolidPeso molecolare:315.45DSPE-PEG1000-RVG29
DSPE-PEG1000-RVG29 is a PEG compound composed of DSPE and rabies virus glycoprotein 29 (RVG29). RVG29 can specifically bind to nicotinic acetylcholine receptors (nAChR) at the blood-brain barrier (BBB) and cross the BBB.Colore e forma:Odour Solidα-Conotoxin EI
CAS:Selective antagonist of neuromuscular nicotinic receptors α1β1γδFormula:C83H125N27O27S5Purezza:98%Colore e forma:SolidPeso molecolare:2093.37Navafenterol
CAS:AZD-8871, a potential COPD and asthma treatment, may work well with ICS.Formula:C38H42N6O6S2Colore e forma:SolidPeso molecolare:742.91Muscarinic toxin 3
CAS:Muscarinic toxin 3 (MT3), a potent non-competitive antagonist of mAChR and adrenoceptors, exhibits pIC50 values of 6.71 for M1, 8.79 for M4, 8.86 for α1A, 7.57Formula:C319H489N89O97S8Purezza:98%Colore e forma:SolidPeso molecolare:7379.35nAChR agonist CMPI hydrochloride
CAS:CMPI hydrochloride: Potent α4:α4 nAChR PAM; EC50 0.26 μM for (α4)3(β2)2 response to ACh; may aid nicotine dependence, neuropsychiatric research.Formula:C18H20Cl2N4OColore e forma:SolidPeso molecolare:379.29(-)-OPC-51803
CAS:(-)-OPC-51803 is an antidiuretic hormone V2 receptor agonist used in the treatment of nocturia and urinary incontinence.Formula:C26H32ClN3O2Purezza:98.73% - 99.59%Colore e forma:SoildPeso molecolare:454MK-0969
CAS:MK-0969 (J-104135) is a possible M3 antagonist for the treatment of chronic obstructive pulmonary disease.Formula:C24H30F2N4O2Colore e forma:SolidPeso molecolare:444.52Biperiden Hydrochloride
CAS:<p>Biperiden HCl is an anti-Parkinson's drug, blocks M1 receptors, manages all Parkinson's types, and is FDA-approved. Non-toxic at 0.11 mg/kg to rats' cognition.</p>Formula:C21H30ClNOPurezza:98%Colore e forma:SolidPeso molecolare:347.92Emraclidine
CAS:Emraclidine (CVL-231) is a novel, highly selective allosteric modulator of the muscarinic M4 receptor positive receptor.Cost-effective and quality-assured.Formula:C20H21F3N4OPurezza:99.96%Colore e forma:SolidPeso molecolare:390.4TIP 39, Tuberoinfundibular Neuropeptide
CAS:TIP39 is a synthetic neuropeptide agonist for human and rat PTH2 receptors from the hypothalamus.Formula:C202H325N61O54SPurezza:98%Colore e forma:SolidPeso molecolare:4504.2Albanin A
<p>Albanin A is a useful organic compound for research related to life sciences and the catalog number is T124310.</p>Formula:C20H18O6Colore e forma:SolidPeso molecolare:354.358Anabaseine
CAS:Anabaseine is a broad nicotinic agonist, favoring alpha-7 AChRs in muscle/brain, and weakly stimulates alpha-4 beta-2 nAChRs.Formula:C10H12N2Colore e forma:SolidPeso molecolare:160.22Flupyradifurone
CAS:<p>Flupyradifurone (flupyradifurone) is a systemic insecticide and nicotinic acetylcholine receptor (nAChR) agonist interfer nervous system of insects.</p>Formula:C12H11ClF2N2O2Purezza:99.83%Colore e forma:SolidPeso molecolare:288.68Anagyrine hydrochloride
CAS:<p>Anagyrine hydrochloride, a quinolizidine from Lupinus albus, targets muscarinic/nicotinic receptors; IC50: 132/2096 µM. It desensitizes nAChR directly.</p>Formula:C15H21ClN2OColore e forma:SolidPeso molecolare:280.79Fentonium bromide
CAS:<p>Fentonium bromide is a biochemical.</p>Formula:C31H34BrNO4Colore e forma:SolidPeso molecolare:564.51Small Cardioactive Peptide B (SCPB)
CAS:SCPB: neurally active peptide, boosts adenylate cyclase in heart/gills, EC50s: 0.1 μM (heart), 1.0 μM (gills).Formula:C52H80N14O11S2Purezza:98%Colore e forma:SolidPeso molecolare:1141.41Muscarine
CAS:Muscarine is a toxic alkaloid found in Amanita muscaria and other fungi of the Inocybe species.Formula:C9H20NO2Purezza:98%Colore e forma:SolidPeso molecolare:174.26Mant-GTPγS
CAS:<p>Mant-GTPγS, an effective GTP analog, displays strong competitive inhibition of adenylyl cyclase (AC). Additionally, it acts as a potent inhibitor of YdeH.</p>Formula:C18H23N6O14P3SColore e forma:SolidPeso molecolare:672.39N-Ethyl-N-(3-pyridylmethyl)amine
CAS:N-Ethyl-N-(3-pyridylmethyl)amine has affinity for nAChR (Ki = 0.97 µM) and can be used in related research in the field of life sciences.Formula:C8H12N2Purezza:99.65%Colore e forma:SolidPeso molecolare:136.19NNC 11-1607
CAS:NNC 11-1607 is a functionally selective agonist of M(1)/M(4) mAChR.Formula:C30H32N6O2S2Colore e forma:SolidPeso molecolare:572.74[D-Trp7,9,10]-Substance P
CAS:<p>Substance P analog that inhibits activation of Gq/11 by M1 muscarinic ACh receptors. Does not inhibit Gi/o activation by M2 ACh receptors.</p>Formula:C79H105N21O13SPurezza:98%Colore e forma:SolidPeso molecolare:1588.89GeX-2
CAS:<p>GeX-2 is a truncated analogue of αO-conotoxin. It has the ability to activate GABAB receptors and inhibit α9α10nAChR as well as CaV2.2 channels. Additionally, GeX-2 is effective in alleviating pain in a rat model of chronic constriction injury.</p>Formula:C103H169N43O27Colore e forma:SolidPeso molecolare:2441.72Aceclidine (hydrochloride)
CAS:agonist of muscarinic receptorsFormula:C9H16ClNO2Purezza:98%Colore e forma:SolidPeso molecolare:205.68DSPE-PEG5000-RVG29
DSPE-PEG5000-RVG29 is a PEG compound comprised of DSPE and rabies virus glycoprotein 29 (RVG29). RVG29 specifically binds to nicotinic acetylcholine receptors (nAChR) at the blood-brain barrier (BBB) and facilitates passage through the BBB.Colore e forma:Odour SolidPerlapine
CAS:Perlapine is an effective and selective HM3DQ DREADD agonist (EC50 = 2.8 nM).Formula:C19H21N3Colore e forma:SolidPeso molecolare:291.39Bensultap
CAS:Bensultap is an agricultural chemical typically used as a pesticide.Formula:C17H21NO4S4Purezza:98%Colore e forma:SolidPeso molecolare:431.61PDE4-IN-4
CAS:PDE4-IN-4 is a compound acting as both a potent M3 antagonist (p IC 50 = 10.2) and a PDE4 inhibitor (p IC 50 = 8.8), designed for inhalation-based treatment ofFormula:C36H37Cl2N3O7SColore e forma:SolidPeso molecolare:726.67Destomycin A
CAS:Destomycin A, an aminoglycoside antibiotic, exhibits activity against bacterial (Gram-positive and Gram-negative), antifungal, and anthelmintic agents. It inhibits peptide synthesis in Escherichia coli cells and stimulates adenylate cyclase in animal tissues.Formula:C20H37N3O13Colore e forma:SolidPeso molecolare:527.52CDD0102 HCl
CAS:CDD0102 HCl is a selective and potent M1 muscarinic receptor agonist for the treatment of Alzheimer's disease.Formula:C8H13ClN4OPurezza:99.7%Colore e forma:SoildPeso molecolare:216.67VU6028418
CAS:VU6028418 is a highly selective, potent, orally active M4mAChR antagonist that acts on hM4 (IC50: 4.1 nM).Colore e forma:SolidThiothixene
CAS:Thiothixene has a wide range of applications in life science related research.Formula:C23H29N3O2S2Colore e forma:SolidPeso molecolare:443.62ANQ-9040
CAS:<p>ANQ-9040 is a nondepolarizing neuromuscular relaxant of the steroid class.</p>Formula:C36H58N2O5SColore e forma:SolidPeso molecolare:630.92(S)-Dinotefuran
CAS:(S)-Dinotefuran, a neonicotinoid, more toxic to bees than its R-isomer, targets α8 nAChR.Formula:C7H14N4O3Colore e forma:SolidPeso molecolare:202.21Proadrenomedullin (1-20), human
CAS:Endogenous peptide; agonist of MRGPRX2 (EC50=251 nM); noncompetitive inhibitor of nicotinic receptors; reduces catecholamine secretion; antihypertensive.Formula:C112H178N36O27Purezza:98%Colore e forma:SolidPeso molecolare:2460.84R-(+)-Cotinine
CAS:<p>R-(+)-Cotinine, an inactive nicotine metabolite, boosts Ach-induced current in human α7 nAChRs.</p>Formula:C10H12N2OColore e forma:SolidPeso molecolare:176.22bPiDDB
CAS:<p>bPiDDB (N,N'-Dodecylbis-Picolinium Bromide) is a nicotinic receptor (nAChR) antagonist.</p>Formula:C24H38Br2N2Purezza:98.72%Colore e forma:SolidPeso molecolare:514.38LtIA-F
LtIA-F, a fluorescent LtIA derivative, aids study of α3β2 nAChR's structure, distribution, and binding domain.Formula:C86H121N25O22S4Colore e forma:SolidPeso molecolare:1985.31Bencycloquidium Bromide
CAS:Bencycloquidium bromide is an M3 muscarinic antagonist that reduces nasal secretion in allergic rhinitis and has high affinity for M3 receptors.Formula:C21H32BrNO2Colore e forma:SolidPeso molecolare:410.39PF-06827443
PF-06827443 is a orally bioavailable, CNS-penetrant M1-selective PAM with minimal agonist activity.Formula:C24H24N2O4Colore e forma:SolidPeso molecolare:404.47Guanylyl Imidodiphosphate (lithium salt)
CAS:Guanylyl Imidodiphosphate (lithium salt) is a non-hydrolyzable GTP analog that increases adenylate cyclase activity.Formula:C10H13Li4N6O13P3Colore e forma:SolidPeso molecolare:545.93Irsogladine maleate
CAS:Compound PDK0375, with CAS No. 84504-69-8, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0375 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.Formula:C9H7Cl2N5Colore e forma:SolidPeso molecolare:256.09trans-Cevimeline hydrochloride
CAS:<p>AF 102A hydrochloride is a biochemical.</p>Formula:C10H18ClNOSColore e forma:SolidPeso molecolare:235.77Hydroxybupropion
CAS:Hydroxybupropion is the major active metabolite of Bupropion and an antagonist of nACh receptor. Hydroxybupropion inhibits norepinephrine uptake (IC50 = 1.7 μM).Formula:C13H18ClNO2Purezza:99.73%Colore e forma:Off-White SolidPeso molecolare:255.74Br-PBTC
CAS:Br-PBTC modulates nAChRs; targets α2/β2,4 subtypes; potent with 0.1-0.6 μM EC50; binds α subunit c-tail.Formula:C14H15BrN2OSColore e forma:SolidPeso molecolare:339.25M4 mAChR agonist-1
CAS:<p>M4 mAChR agonist-1 (4-Piperidinecarboxamide, 1-(5,6-dimethylthieno[2,3-d]pyrimidin-4-yl)-) is an effective agonist of M4 mAChR (EC50 >10 μM).</p>Formula:C14H18N4OSPurezza:99.14%Colore e forma:SolidPeso molecolare:290.38Ebiratide
CAS:Ebiratide is an analog of ACTH 4-9.Formula:C48H73N11O10SPurezza:98%Colore e forma:SolidPeso molecolare:996.23
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