AChR
Gli inibitori del recettore dell'acetilcolina (AChR) sono composti che bloccano l'attività dei recettori dell'acetilcolina, fondamentali per la neurotrasmissione nei sistemi nervoso centrale e periferico. Gli AChR svolgono un ruolo cruciale nella contrazione muscolare, nella memoria e nelle funzioni cognitive. Gli inibitori degli AChR vengono utilizzati per studiare condizioni come la miastenia grave, l'Alzheimer e altri disturbi neurologici. Modulando l'attività degli AChR, questi inibitori possono aiutare a svelare le complessità della segnalazione colinergica nel cervello. Presso CymitQuimica, offriamo una gamma di inibitori degli AChR per supportare la tua ricerca in neuroscienze, farmacologia e malattie neurodegenerative.
Trovati 617 prodotti di "AChR"
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SSR180711 hydrochloride
CAS:SSR180711 hydrochloride (SSR-180711A HCl) is an Alpha7 nicotinic acetylcholine partial agonist that can be used to study neurolysis.Formula:C14H18BrClN2O2Purezza:99.22%Colore e forma:SolidPeso molecolare:361.66Varenicline Hydrochloride
CAS:Varenicline Hydrochloride (CP 526555) is an orally active partial agonist of the α4β2 nicotinic acetylcholine receptor (α4β2 nAChR, IC50 = 250 nM).Formula:C13H14ClN3Purezza:99.854%Colore e forma:SolidPeso molecolare:247.72Cevimeline hydrochloride
CAS:Cevimeline HCl is a muscarinic agonist enhancing salivary and sweat gland secretion.Formula:C10H18ClOSColore e forma:SolidPeso molecolare:235.77Glycerophosphoinositol choline
CAS:Glycerophosphoinositol choline is the salt of choline and glycerophosphoinositol.Formula:C14H32NO12PColore e forma:SolidPeso molecolare:437.38Ispronicline
CAS:Ispronicline (TC-1734) An orally active, selective, and potent α4β2 nAChR partial agonist with antidepressant, neuroprotective, and long-lasting cognitiveFormula:C14H22N2OPurezza:97.70% - 99.16%Colore e forma:SolidPeso molecolare:234.34ABT-107
CAS:ABT-107: α7 neuronal receptor agonist; protects rats' brains from 6-OHDA-induced damage.Formula:C19H20N4OColore e forma:SolidPeso molecolare:320.396NSC 23766
CAS:NSC 23766 is a Rac1 GTPase inhibitor by targeting GEFs, inhibiting cell proliferation.NSC23766 competitively inhibits M2 mAChR-induced Rac1 activation.Formula:C24H35N7Purezza:99.49%Colore e forma:SolidPeso molecolare:421.58(±)-Darifenacin
CAS:(±)-Darifenacin is the racemate of Darifenacin. Darifenacin is a selective antagonist of M3 muscarinic receptor.Formula:C28H30N2O2Colore e forma:SolidPeso molecolare:426.55VU0467485
CAS:VU0467485 boosts ACh at M4 receptors (EC50: 26.6 nM rat, 78.8 nM human), selective for M4 over M1/2/3/5.Formula:C17H17FN4O2SPurezza:98%Colore e forma:SolidPeso molecolare:360.41NKH477
CAS:NKH477 (Colforsin dapropate hydrochloride) is a derivative of forskolin with antidepressant activity.Formula:C27H44ClNO8Purezza:98% - 98%Colore e forma:SolidPeso molecolare:546.09Tolterodine
CAS:Tolterodine ((R)-(+)-Tolterodine) is an mACh antagonist used in the treatment of detrusor instability and overactive bladder syndrome.Formula:C22H31NOPurezza:99.71%Colore e forma:White Like Or Light Brown Crystalline PowderPeso molecolare:325.49Clorprenaline
CAS:Clorprenaline is a β-adrenergic receptor agonist that activates adenylate cyclase, relaxation of bronchial smooth muscle cells. anti-inflammatory.Formula:C11H16ClNOPurezza:98.9%Colore e forma:SolidPeso molecolare:213.7NBTGR
CAS:NBTGR is a potent nucleoside transport inhibitor(adenosine uptake ,Ki of 70 nM).Formula:C17H18N6O6SPurezza:98%Colore e forma:SolidPeso molecolare:434.43Cevimeline
CAS:Cevimeline: muscarinic agonist, treats dry mouth & Sjögren's, boosts saliva post-cancer radiotherapy.Formula:C10H17NOSColore e forma:Off-White SolidPeso molecolare:199.31Pirmenol hydrochloride
CAS:Pirmenol hydrochloride functions by inhibiting I_K.ACh through the blockade of muscarinic receptors, demonstrating a potent effect with an IC_50 value of 0.1 μMFormula:C22H31ClN2OColore e forma:SolidPeso molecolare:374.95DL-Cystine
CAS:DL-Cystine is a cysteine derivative that inhibits endothelial cell proliferation by regulating TGFβ1. a GPR inhibitor and nAChR agonist .Formula:C6H12N2O4S2Colore e forma:SolidPeso molecolare:240.3NS3861 fumarate
CAS:NS3861 fumarate, a partial α3β4 nAChR agonist, binds α3β2, α4β4, α4β2 with Ki values of 0.62, 25, 7.8, 55 nM.Formula:C16H18BrNO4SColore e forma:SolidPeso molecolare:400.29Sabcomeline hydrochloride
CAS:Sabcomeline is a selective M1 receptor partial agonist.Formula:C10H16ClN3OColore e forma:SolidPeso molecolare:229.71Tebanicline dihydrochloride
CAS:Tebanicline dihydrochloride: oral analgesic, nAChR modulator, Ki=37 pM at α4β2 receptors, inhibits cytisine binding.Formula:C9H13Cl3N2OColore e forma:SolidPeso molecolare:271.57Biperiden
CAS:Biperiden is a muscarinic antagonist for Parkinson's and drug-induced extrapyramidal symptoms.Formula:C21H29NOPurezza:99.65%Colore e forma:Crystals SolidPeso molecolare:311.46Tebanicline hydrochloride
CAS:Tebanicline hydrochloride (Ebanicline hydrochloride) , is an effective synthetic nicotinic (non-opioid) analgesic drug.Formula:C9H12Cl2N2OPurezza:91.74% - 98.78%Colore e forma:SolidPeso molecolare:235.11VU0119498
CAS:VU0119498 is a M1 muscarinic receptor agonist (EC50 = 3.1 μM) and pan mAChR M3, M5 positive allosteric modulator (PAM),and is a neuroprotective agent.Formula:C15H10BrNO2Purezza:97.56%Colore e forma:SolidPeso molecolare:316.15BNC210
CAS:BNC210 (IW-2143) is a α7 nAChR negative allosteric modulator. BNC210 has potent activity in animal models of anxiety and depression.Formula:C17H23N3O3Purezza:97.05% - >99.99%Colore e forma:SolidPeso molecolare:317.38Harman hydrochloride
CAS:Harman hydrochloride triggers CYP1A1 gene via AhR, potentially causing mutations and cancer.Formula:C12H11ClN2Purezza:99.35%Colore e forma:SolidPeso molecolare:218.68Nitrobenzylthioinosine
CAS:<p>Nitrobenzylthioinosine (NBMPR) is an inhibitor of ENT1 transporter that binds to ENT1 transporter with high affinity.</p>Formula:C17H17N5O6SPurezza:99.69% - 99.74%Colore e forma:Off-White SolidPeso molecolare:419.41VU0152100
CAS:<p>VU0152100 is an effective and selective allosteric potentiator of M4 mAChR (EC50: 380 ± 93 nM).</p>Formula:C18H19N3O2SPurezza:99.56%Colore e forma:SolidPeso molecolare:341.43NS9283
CAS:<p>NS9283, a positive allosteric modulator selective for the α4β2 form, reduces ethanol consumption.</p>Formula:C14H8N4OPurezza:99.12%Colore e forma:SolidPeso molecolare:248.24ML380
CAS:<p>ML380 is a highly potent and the first CNS penetrant M5 positive allosteric modulator (PAM).</p>Formula:C23H25F3N4O3SPurezza:99.69%Colore e forma:SolidPeso molecolare:494.53Isopropamide Iodide
CAS:<p>Isopropamide iodide: long-acting anticholinergic, treats peptic ulcers, GI disorders, Alzheimer's.</p>Formula:C23H33IN2OPurezza:99.67%Colore e forma:SolidPeso molecolare:480.43Mecamylamine hydrochloride
CAS:Mecamylamine hydrochloride (Mevasin) is a nicotinic antagonist, used as a ganglionic blocker in hypertension.Formula:C11H22ClNPurezza:99.76% - >99.99%Colore e forma:White SolidPeso molecolare:203.75Nitenpyram
CAS:<p>Nitenpyram (Capstar) is a nicotinic acetylcholine receptor (AchR) agonist, used as veterinary medicine to treat parasites of livestock and pets.</p>Formula:C11H15ClN4O2Purezza:99.03%Colore e forma:Light-Yellow CrystalPeso molecolare:270.72Encenicline
CAS:Encenicline (EVP-6124), a selective α7 nAChRs agonist, targets cognitive impairment in schizophrenia and Alzheimer's.Formula:C16H17ClN2OSPurezza:99.20%Colore e forma:SolidPeso molecolare:320.84Mc-Val-Ala-PAB
CAS:<p>Mc-Val-Ala-PAB, an effective linker, is utilized in antibody-drug-conjugate (ADC).</p>Formula:C25H34N4O6Purezza:98.34% - 99.24%Colore e forma:SolidPeso molecolare:486.56Solifenacin
CAS:Solifenacin (YM905 free base) (YM905 free base) is a novel muscarinic receptor antagonist, its pKis for M1, M2 and M3 receptors is of 7.6, 6.9 and 8.0,Formula:C23H26N2O2Purezza:99.87%Colore e forma:SolidPeso molecolare:362.46Solifenacin hydrochloride
CAS:Solifenacin Hcl is a muscarinic receptor antagonist.Formula:C23H27ClN2O2Purezza:98%Colore e forma:SolidPeso molecolare:398.93Oxyphencyclimine Hydrochloride
CAS:<p>Oxyphencyclimine Hydrochloride (Ulcociclinina) is a synthetic tertiary amine and antimuscarinic agent with antispasmodic and antisecretory activities.</p>Formula:C20H29ClN2O3Purezza:99.55%Colore e forma:SolidPeso molecolare:380.91VU0467154
CAS:VU0467154 is a positive allosteric modulator of the M4 muscarinic acetylcholine receptor.Formula:C17H15F3N4O3S2Purezza:99.51% - 99.53%Colore e forma:SolidPeso molecolare:444.45Mecamylamine
CAS:<p>Mecamylamine: oral, noncompetitive nAChR blocker, crosses blood-brain barrier, for neuropsychiatric and hypertension research.</p>Formula:C11H21NColore e forma:SolidPeso molecolare:167.29Ethyl (triphenylphosphoranylidene) acetate
CAS:<p>Ethyl (triphenylphosphoranylidene) acetate ((Carbethoxymethylene)triphenylphosphorane) may act as an cholinesterase inhibitor that inhibits AChE and BChE.</p>Formula:C22H21O2PPurezza:97.985%Colore e forma:White Or Slight Yellow PowderPeso molecolare:348.37Propiverine
CAS:Propiverine reduces muscle spasms by limiting calcium influx, targeting bladder smooth muscles, aiding OAB research.Formula:C23H29NO3Colore e forma:SolidPeso molecolare:367.48NS 1738
CAS:NS 1738 (NSC-213859) is a positive allosteric modulator of the α7-containing neuronal nicotinic acetylcholine receptors (nAChRs)Formula:C14H9Cl2F3N2O2Purezza:99.11%Colore e forma:SolidPeso molecolare:365.13Oxyphenonium bromide
CAS:<p>Oxyphenonium bromide is an anticholinergic used to study and treat ulcers and relieve visceral spasms.</p>Formula:C21H34BrNO3Purezza:98.96%Colore e forma:SolidPeso molecolare:428.404Fesoterodine
CAS:Fesoterodine is an oral mAChR blocker (pKi: 7.3-8.0) for M1-M5, used to treat OAB.Formula:C26H37NO3Purezza:97.1%Colore e forma:SolidPeso molecolare:411.58DMAB-anabaseine dihydrochloride
CAS:<p>DMAB-anabaseine dihydrochloride (N,N-dimethyl-4-[(E)-(6-pyridin-3-yl-3,4-dihydro-2H-pyridin-5-ylidene)methyl]aniline;dihydrochloride) is an α7-containing</p>Formula:C19H23Cl2N3Purezza:99.91%Colore e forma:SolidPeso molecolare:364.31Propantheline
CAS:Propantheline: oral muscarinic receptor blocker for smooth muscle issues, hyperhidrosis, and bladder control.Formula:C23H30NO3Colore e forma:SolidPeso molecolare:368.49MC-Val-Cit-PABC-PNP
CAS:MC-Val-Cit-PABC-PNP, also known as Mc-Val-Cit-PABC-PNP, is a cathepsin cleavable ADC peptide linker.Formula:C35H43N7O11Purezza:97.2% - 98.055%Colore e forma:SolidPeso molecolare:737.76Batefenterol Succinate
CAS:Batefenterol Succinate is a first-in-class inhaled bifunctional bronchodilator possessing muscarinic receptor antagonist and β2-adrenoceptor agonist properties.Formula:C44H48ClN5O11Colore e forma:SolidPeso molecolare:858.34Cyclopentolate Hydrochloride
CAS:Cyclopentolate Hydrochloride is a muscarinic acetylcholine receptors antagonist with Kis of 1.62, 27.5, and 2.63 nM for M1, M2, and M3 receptors, respectively.Formula:C17H26ClNO3Purezza:99.91%Colore e forma:SolidPeso molecolare:327.85A-867744
CAS:<p>A-867744 is an effective and selective type II positive allosteric modulator of the α7 nAChR (EC50: 1.0 μM).</p>Formula:C20H19ClN2O3SPurezza:95.66%Colore e forma:SolidPeso molecolare:402.89Bestim
CAS:Bestim is an immunomodulatory dipeptide that is synthetic.Formula:C16H19N3O5Purezza:99.76%Colore e forma:SolidPeso molecolare:333.34
