AChR
Gli inibitori del recettore dell'acetilcolina (AChR) sono composti che bloccano l'attività dei recettori dell'acetilcolina, fondamentali per la neurotrasmissione nei sistemi nervoso centrale e periferico. Gli AChR svolgono un ruolo cruciale nella contrazione muscolare, nella memoria e nelle funzioni cognitive. Gli inibitori degli AChR vengono utilizzati per studiare condizioni come la miastenia grave, l'Alzheimer e altri disturbi neurologici. Modulando l'attività degli AChR, questi inibitori possono aiutare a svelare le complessità della segnalazione colinergica nel cervello. Presso CymitQuimica, offriamo una gamma di inibitori degli AChR per supportare la tua ricerca in neuroscienze, farmacologia e malattie neurodegenerative.
Trovati 617 prodotti di "AChR"
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Oxyphenonium bromide
CAS:<p>Oxyphenonium bromide is an anticholinergic used to study and treat ulcers and relieve visceral spasms.</p>Formula:C21H34BrNO3Purezza:98.96%Colore e forma:SolidPeso molecolare:428.404Dronedarone
CAS:<p>Dronedarone (SR 33589) is an amiodarone analogue which has an effective and promising treatment for Atrial fibrillation.</p>Formula:C31H44N2O5SPurezza:98.85% - 99.58%Colore e forma:SolidPeso molecolare:556.76EB-3D
CAS:EB-3D is a potent and selective choline kinase alpha 1 (ChoKα1) inhibitor(IC50 : 1 μM).with anti-cancer activity.Formula:C30H36Br2N4O2Purezza:99.48%Colore e forma:SolidPeso molecolare:644.4Propantheline
CAS:Propantheline: oral muscarinic receptor blocker for smooth muscle issues, hyperhidrosis, and bladder control.Formula:C23H30NO3Colore e forma:SolidPeso molecolare:368.49MC-Val-Cit-PABC-PNP
CAS:MC-Val-Cit-PABC-PNP, also known as Mc-Val-Cit-PABC-PNP, is a cathepsin cleavable ADC peptide linker.Formula:C35H43N7O11Purezza:97.2% - 98.055%Colore e forma:SolidPeso molecolare:737.76Bestim
CAS:Bestim is an immunomodulatory dipeptide that is synthetic.Formula:C16H19N3O5Purezza:99.76%Colore e forma:SolidPeso molecolare:333.34Pempidine HCl
CAS:Pempidine HCl, a nicotinic antagonist and former hypertension treatment, now mainly serves as a lab tool.Formula:C10H22ClNColore e forma:SolidPeso molecolare:191.74Rivanicline hemioxalate
<p>Rivanicline hemioxalate is a selective α4β2 nicotinic receptor agonist (K i =26 nM), over 1,000x preference to α7 (K i =3.6 μM), with limited side effects.</p>Formula:C12H16N2O4Purezza:98%Colore e forma:SolidPeso molecolare:207.23VU0152099
CAS:VU0152099 is a potent and selective M4 mAChR allosteric potentiator(EC50 = 380 ± 93 nM).Formula:C18H17N3O3SPurezza:98.46%Colore e forma:SolidPeso molecolare:355.41Adiphenine
CAS:Adiphenine is an inhibitor of nicotinic receptors.Formula:C20H25NO2Colore e forma:SolidPeso molecolare:311.42Coluracetam
CAS:Coluracetam (MKC-231)(MKC-231) is a Choline Uptake Enhancer.Formula:C19H23N3O3Purezza:99.96%Colore e forma:SolidPeso molecolare:341.4Aclidinium bromide
CAS:<p>Aclidinium bromide (LAS-W 330) is a synthetic anticholinergic agent that is used as an inhalant for treatment of acute bronchospasm due to chronic bronchitis.</p>Formula:C26H30NO4S2·BrPurezza:99.53% - 99.69%Colore e forma:SolidPeso molecolare:564.55Encenicline hydrochloride
CAS:Encenicline hydrochloride (EVP-6124 hydrochloride) is a new-type partial agonist of α7 neuronal nicotinic acetylcholine receptors (nAChRs).Formula:C16H17ClN2OS·HClPurezza:98.34% - 99.85%Colore e forma:SolidPeso molecolare:357.3suvn-911
CAS:suvn-911 is a potent and selective antagonist of neuronal nicotinic acetylcholine α4β2 receptor (Ki = 1.5 nM) with antidepressant activity.Formula:C11H14Cl2N2OPurezza:98.88%Colore e forma:SolidPeso molecolare:261.15JHU37152
CAS:JHU37152 is a DREADD agonist; Ki: 1.8 nM at hM3Dq, 8.7 nM at hM4Di; EC50: 5 nM (hM3Dq), 0.5 nM (hM4Di) in HEK-293 cell assays.Formula:C19H20ClFN4Purezza:99.72%Colore e forma:SolidPeso molecolare:358.84Umeclidinium bromide
CAS:Umeclidinium bromide (GSK573719A) is a novel mAChR antagonist.Formula:C29H34BrNO2Purezza:98.4% - 99.89%Colore e forma:SolidPeso molecolare:508.49VU0238441
CAS:VU0238441 is agonist of Muscarinic acetylcholine receptor M5 (human) with EC50 of 2.1μM.Formula:C16H9ClF3NO2Purezza:100%Colore e forma:SolidPeso molecolare:339.7(S)-UFR2709
CAS:(S)-UFR2709, a nAChR competitive antagonist, favors α4β2 over α7, reduces anxiety and alcohol use in rats.Formula:C13H17NO2Colore e forma:SolidPeso molecolare:219.284Oxyphencyclimine
CAS:Oxyphencyclimine is a muscarinic receptor antagonist (MRA) anticholinergic drug used to treat peptic ulcers.Formula:C20H28N2O3Colore e forma:SolidPeso molecolare:344.45mAChR-IN-1 hydrochloride
CAS:mAChR-IN-1 hydrochloride is a potent muscarinic cholinergic receptor (mAChR) antagonist, with an IC50 of 17 Nm.Formula:C23H26ClIN2O2Purezza:99.87%Colore e forma:SolidPeso molecolare:524.82Benzetimide hydrochloride
CAS:Benzetimide hydrochloride (R4929) is an antagonist of muscarinic acetylcholine receptor.treatment neuroleptic-induced parkinsonism.Formula:C23H27ClN2O2Purezza:99.32%Colore e forma:Off-White PowderPeso molecolare:398.93Batefenterol Succinate
CAS:Batefenterol Succinate is a first-in-class inhaled bifunctional bronchodilator possessing muscarinic receptor antagonist and β2-adrenoceptor agonist properties.Formula:C44H48ClN5O11Colore e forma:SolidPeso molecolare:858.34Solifenacin
CAS:Solifenacin (YM905 free base) (YM905 free base) is a novel muscarinic receptor antagonist, its pKis for M1, M2 and M3 receptors is of 7.6, 6.9 and 8.0,Formula:C23H26N2O2Purezza:99.87%Colore e forma:SolidPeso molecolare:362.46Pirmenol
CAS:Pirmenol is a new antiarrhythmic drugFormula:C22H30N2OPurezza:97.24%Colore e forma:SolidPeso molecolare:338.49LY2119620
CAS:LY2119620 is a specific, and allosteric agonist of human M2 and M4 muscarinic acetylcholine receptors.Formula:C19H24ClN5O3SPurezza:99.7%Colore e forma:SolidPeso molecolare:437.94Cyclodrine hydrochloride
CAS:Cyclodrine hydrochloride is a dual cholinergic muscarinic receptor (mAChR) and nicotinic receptor (nAChR) antagonist that can be used in the study ofFormula:C19H30ClNO3Purezza:98.59%Colore e forma:SolidPeso molecolare:355.9Ilmetropium iodide
CAS:Ilmetropium iodide is a bronchodilator.Formula:C20H30INO3Purezza:98.45%Colore e forma:SolidPeso molecolare:459.36Darifenacin
CAS:Darifenacin (UK-88525) is a muscarinic receptor M3 antagonist with anticonvulsant activity and can be used to study urinary incontinence and overactive bladder.Formula:C28H30N2O2Purezza:99.78%Colore e forma:SolidPeso molecolare:426.55BNC210
CAS:BNC210 (IW-2143) is a α7 nAChR negative allosteric modulator. BNC210 has potent activity in animal models of anxiety and depression.Formula:C17H23N3O3Purezza:97.05% - >99.99%Colore e forma:SolidPeso molecolare:317.38Brompheniramine
CAS:Brompheniramine, an alkylamine antihistamine, targets H1 receptors (Kd=6.06nM) and has anticholinergic/depressant qualities. Blocks Ca/Na/hERG channels.Formula:C16H19BrN2Colore e forma:SolidPeso molecolare:319.24Harman hydrochloride
CAS:Harman hydrochloride triggers CYP1A1 gene via AhR, potentially causing mutations and cancer.Formula:C12H11ClN2Purezza:99.35%Colore e forma:SolidPeso molecolare:218.68Nor-benzetimide
CAS:Norbenzetimide, an organic compound, is prepared from benzetimide by catalytic transfer hydrogenolysis.Formula:C16H20N2O2Purezza:98.63%Colore e forma:SolidPeso molecolare:272.34Ursulcholic acid
CAS:Ursulcholic acid (Ursulcholic) is a water-soluble anticholinergic compound.Formula:C24H40O10S2Purezza:98%Colore e forma:SolidPeso molecolare:552.7W-84 dibromide
CAS:<p>W-84 dibromide (HDMPPA) is a M2-receptor selective modulator.</p>Formula:C32H44Br2N4O4Purezza:95.56%Colore e forma:SolidPeso molecolare:708.52Nitrocaramiphen hydrochloride
CAS:Nitrocaramiphen hydrochloride is a selective M1 muscarinic antagonist and inhibits binding to sigma sites in brain.Formula:C18H27ClN2O4Purezza:99.74%Colore e forma:SolidPeso molecolare:370.87CCMI
CAS:<p>CCMI (AVL-3288) is a potent and selective modulator of α7 nAChR-positive allosteric.</p>Formula:C19H15Cl2N3O2Purezza:>99.99%Colore e forma:SolidPeso molecolare:388.25SEN12333
CAS:<p>SEN12333 is an α7 nicotinic acetylcholine receptor (nAChR) agonist</p>Formula:C20H25N3O2Purezza:99.02%Colore e forma:SolidPeso molecolare:339.43Glycopyrrolate
CAS:Glycopyrrolate: muscarinic antagonist, antispasmodic for GI issues, reduces salivation with anesthesia.Formula:C19H28BrNO3Purezza:99.41% - 99.64%Colore e forma:SolidPeso molecolare:398.339-Ethyladenine
CAS:9-Ethyladenine (6-Amino-9-ethylpurine) is a partially potent APRT (adenine phosphoribosyltransferase) inhibitor [1].Formula:C7H9N5Purezza:99.35% - 99.37%Colore e forma:SolidPeso molecolare:163.184BP-TQS
CAS:4BP-TQS is an allosteric agonist of α7 nAChRs.Formula:C18H17BrN2O2SPurezza:99.96%Colore e forma:SolidPeso molecolare:405.31PNU-282987 S enantiomer free base
CAS:PNU-282987 S enantiomer free base is an agonist of α7 nicotinic acetylcholine receptor (α7 nAChR).Formula:C14H17ClN2OPurezza:99.74%Colore e forma:SolidPeso molecolare:264.75BQCA
CAS:<p>BQCA (benzylquinolone carboxylic acid) a highly selective allosteric M1 mAChR modulator.</p>Formula:C18H15NO4Purezza:97.22%Colore e forma:SolidPeso molecolare:309.32TBPB
CAS:<p>TBPB is an allosteric M1 mAChR agonist.</p>Formula:C25H32N4OPurezza:97.87% - 99.9%Colore e forma:SolidPeso molecolare:404.55Piperidolate
CAS:Piperidolate inhibits intestinal cramp induced by acetylcholineFormula:C21H25NO2Purezza:98.45%Colore e forma:SolidPeso molecolare:323.43Dicyclomine
CAS:Dicyclomine: oral muscarinic antagonist, eases GI muscle spasms, high affinity for M1/M2 receptors, Ki of 5.1 nM/54.6 nM.Formula:C19H35NO2Colore e forma:SolidPeso molecolare:309.49A 582941 HCl (848591-90-2(free base))
<p>A-582941 is a alpha7 neuronal nicotinic receptor agonist with broad spectrum cognition-enhancing properties</p>Formula:C17H21ClN4Purezza:99.83%Colore e forma:SolidPeso molecolare:316.83DMAB-anabaseine dihydrochloride
CAS:<p>DMAB-anabaseine dihydrochloride (N,N-dimethyl-4-[(E)-(6-pyridin-3-yl-3,4-dihydro-2H-pyridin-5-ylidene)methyl]aniline;dihydrochloride) is an α7-containing</p>Formula:C19H23Cl2N3Purezza:99.91%Colore e forma:SolidPeso molecolare:364.31Revefenacin
CAS:Revefenacin (TD-4208) is a mAChR antagonist has a high affinity on M3 receptor( Ki : 0.18 nM),and potentially useful for the treatment of respiratory disease.Formula:C35H43N5O4Purezza:98.12%Colore e forma:SolidPeso molecolare:597.75Ethyl (triphenylphosphoranylidene) acetate
CAS:<p>Ethyl (triphenylphosphoranylidene) acetate ((Carbethoxymethylene)triphenylphosphorane) may act as an cholinesterase inhibitor that inhibits AChE and BChE.</p>Formula:C22H21O2PPurezza:97.985%Colore e forma:White Or Slight Yellow PowderPeso molecolare:348.37Fesoterodine
CAS:Fesoterodine is an oral mAChR blocker (pKi: 7.3-8.0) for M1-M5, used to treat OAB.Formula:C26H37NO3Purezza:97.1%Colore e forma:SolidPeso molecolare:411.58
