AChR
Gli inibitori del recettore dell'acetilcolina (AChR) sono composti che bloccano l'attività dei recettori dell'acetilcolina, fondamentali per la neurotrasmissione nei sistemi nervoso centrale e periferico. Gli AChR svolgono un ruolo cruciale nella contrazione muscolare, nella memoria e nelle funzioni cognitive. Gli inibitori degli AChR vengono utilizzati per studiare condizioni come la miastenia grave, l'Alzheimer e altri disturbi neurologici. Modulando l'attività degli AChR, questi inibitori possono aiutare a svelare le complessità della segnalazione colinergica nel cervello. Presso CymitQuimica, offriamo una gamma di inibitori degli AChR per supportare la tua ricerca in neuroscienze, farmacologia e malattie neurodegenerative.
Trovati 617 prodotti di "AChR"
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α-Conotoxin MII acetate
α-Conotoxin MII acetate is a 16-amino acid peptide from the venom of the marine snail Conus magus.Formula:C69H107N23O24S4Purezza:94.82% - 97.79%Colore e forma:SolidPeso molecolare:1770.99Anisotropine Methylbromide
CAS:Anisotropine Methylbromide is an anticholinergic agent and has been used for relief of gastrointestinal spasm and for the suppression of gastric acid secretion.Formula:C17H32BrNO2Purezza:99.73%Colore e forma:Crystals From Acetone SolidPeso molecolare:362.35ST034307
CAS:ST034307 is an effective and selective inhibitor of adenylyl cyclase 1 (IC50: 2.3 μM).Formula:C10H4Cl4O2Purezza:99.28%Colore e forma:SolidPeso molecolare:297.95Adiphenine
CAS:Adiphenine is an inhibitor of nicotinic receptors.Formula:C20H25NO2Colore e forma:SolidPeso molecolare:311.42Cyclodrine hydrochloride
CAS:Cyclodrine hydrochloride is a dual cholinergic muscarinic receptor (mAChR) and nicotinic receptor (nAChR) antagonist that can be used in the study ofFormula:C19H30ClNO3Purezza:98.59%Colore e forma:SolidPeso molecolare:355.9PHA 568487
CAS:PHA 568487: α-7 nAChR agonist, rapid brain uptake, lessens oxidative stress & neuroinflammation.Formula:C20H24N2O7Colore e forma:SolidPeso molecolare:404.419PHA 568487 free base
CAS:<p>PHA 568487 free base, an α7 nicotinic receptor agonist, designed to reduce bioactivation and improve in vivo tolerability.</p>Formula:C16H20N2O3Purezza:99.74%Colore e forma:SolidPeso molecolare:288.34Mc-Val-Ala-PAB
CAS:<p>Mc-Val-Ala-PAB, an effective linker, is utilized in antibody-drug-conjugate (ADC).</p>Formula:C25H34N4O6Purezza:98.34% - 99.24%Colore e forma:SolidPeso molecolare:486.56Oxyphencyclimine
CAS:Oxyphencyclimine is a muscarinic receptor antagonist (MRA) anticholinergic drug used to treat peptic ulcers.Formula:C20H28N2O3Colore e forma:SolidPeso molecolare:344.45suvn-911
CAS:suvn-911 is a potent and selective antagonist of neuronal nicotinic acetylcholine α4β2 receptor (Ki = 1.5 nM) with antidepressant activity.Formula:C11H14Cl2N2OPurezza:98.88%Colore e forma:SolidPeso molecolare:261.15Propantheline
CAS:Propantheline: oral muscarinic receptor blocker for smooth muscle issues, hyperhidrosis, and bladder control.Formula:C23H30NO3Colore e forma:SolidPeso molecolare:368.49Piperidolate hydrochloride
CAS:Piperidolate hydrochloride, an antimuscarinic, reduces acetylcholine-induced intestinal spasms in rats and dogs.Formula:C21H26ClNO2Purezza:99.5%Colore e forma:SolidPeso molecolare:359.89TQS
CAS:TQS (4-Naphthalen-1-yl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-8-sulfonamide) is a positive allosteric modulator of α7 nACh receptors.Formula:C22H20N2O2SPurezza:98.56%Colore e forma:SolidPeso molecolare:376.47KH7
CAS:KH7 is a soluble inhibitor of adenylyl cyclase (sAC)-specific.Formula:C17H15BrN4O2SPurezza:98.43%Colore e forma:SolidPeso molecolare:419.3Succinylcholine Chloride Dihydrate
CAS:<p>Succinylcholine Chloride Dihydrate (Succinyldicholine dichloride) is a nicotinic AChR agonist and also acts as a depolarizing neuromuscular blocker.</p>Formula:C14H30N2O4·2Cl·2H2OPurezza:99.87%Colore e forma:White SolidPeso molecolare:397.34Nitenpyram
CAS:<p>Nitenpyram (Capstar) is a nicotinic acetylcholine receptor (AchR) agonist, used as veterinary medicine to treat parasites of livestock and pets.</p>Formula:C11H15ClN4O2Purezza:99.03%Colore e forma:Light-Yellow CrystalPeso molecolare:270.72Procyclidine hydrochloride
CAS:<p>Procyclidine hydrochloride ((±)-Procyclidine hydrochlorid) is a potent anticholinergic agent and also have NMDA antagonist properties.</p>Formula:C19H30ClNOPurezza:99.24% - 99.88%Colore e forma:Crystals From Petroleum Ether White PowderPeso molecolare:323.9NS9283
CAS:<p>NS9283, a positive allosteric modulator selective for the α4β2 form, reduces ethanol consumption.</p>Formula:C14H8N4OPurezza:99.12%Colore e forma:SolidPeso molecolare:248.24Sofpironium bromide
CAS:<p>Sofpironium bromide (BBI4000) belongs to a class of drugs called anticholinergics, which exert their effect by blocking the action of acetylcholine.</p>Formula:C22H32BrNO5Purezza:98.85%Colore e forma:SolidPeso molecolare:470.4Batefenterol
CAS:<p>Batefenterol (GSK961081) is a muscarinic antagonist and β2-agonist with high affinity (Ki: 1.4/1.3/3.7 nM).</p>Formula:C40H42ClN5O7Purezza:97.94% - 98.4%Colore e forma:SolidPeso molecolare:740.24Nanofin
CAS:<p>Nanofin (Lupetidine) is a neuropathic blocker, with antihypertensive effect.</p>Formula:C7H15NPurezza:97.38% - 99.818%Colore e forma:Clear Colorless To Slightly Yellow LiquidPeso molecolare:113.2MC-Val-Cit-PABC-PNP
CAS:MC-Val-Cit-PABC-PNP, also known as Mc-Val-Cit-PABC-PNP, is a cathepsin cleavable ADC peptide linker.Formula:C35H43N7O11Purezza:97.2% - 98.055%Colore e forma:SolidPeso molecolare:737.76Blarcamesine
CAS:<p>Blarcamesine (AVex-73) is a muscarinic M1 agonist potentially for the treatment of Alzheimer's disease.</p>Formula:C19H23NOPurezza:99.87%Colore e forma:SolidPeso molecolare:281.39ML380
CAS:<p>ML380 is a highly potent and the first CNS penetrant M5 positive allosteric modulator (PAM).</p>Formula:C23H25F3N4O3SPurezza:99.69%Colore e forma:SolidPeso molecolare:494.53PNU-120596
CAS:<p>PNU-120596 (NSC-216666) is a positive allosteric modulator of α7 nAChR with EC50 of 216 nM.</p>Formula:C13H14ClN3O4Purezza:99.82%Colore e forma:SolidPeso molecolare:311.72NS 1738
CAS:NS 1738 (NSC-213859) is a positive allosteric modulator of the α7-containing neuronal nicotinic acetylcholine receptors (nAChRs)Formula:C14H9Cl2F3N2O2Purezza:99.11%Colore e forma:SolidPeso molecolare:365.13Nitrocaramiphen hydrochloride
CAS:Nitrocaramiphen hydrochloride is a selective M1 muscarinic antagonist and inhibits binding to sigma sites in brain.Formula:C18H27ClN2O4Purezza:99.74%Colore e forma:SolidPeso molecolare:370.87A 582941 HCl (848591-90-2(free base))
<p>A-582941 is a alpha7 neuronal nicotinic receptor agonist with broad spectrum cognition-enhancing properties</p>Formula:C17H21ClN4Purezza:99.83%Colore e forma:SolidPeso molecolare:316.83Solifenacin
CAS:Solifenacin (YM905 free base) (YM905 free base) is a novel muscarinic receptor antagonist, its pKis for M1, M2 and M3 receptors is of 7.6, 6.9 and 8.0,Formula:C23H26N2O2Purezza:99.87%Colore e forma:SolidPeso molecolare:362.46Syn-Ake acetate
CAS:Syn-Ake acetate (Dipeptide diaminobutyroyl benzylamide) is a muscarinic acetylcholine receptor antagonist.Formula:C19H29N5O3·2(C2H4O2)Purezza:99.60%Colore e forma:SolidPeso molecolare:495.58Velufenacin
CAS:Velufenacin is an antagonist of muscarinic receptor[1].Formula:C19H20ClFN2O2Purezza:99.65%Colore e forma:SolidPeso molecolare:362.83Mepenzolate Bromide
CAS:<p>Mepenzolate Bromide (Colibantil) is a muscarinic antagonist used to treat gastrointestinal conditions.</p>Formula:C21H26BrNO3Purezza:95.73% - 99.21%Colore e forma:SolidPeso molecolare:420.34AF-710B
CAS:<p>AF710B is an enantiomer of AF710. AF-710B is also a sigma and M1 muscarinic receptors agonist.</p>Formula:C20H27N3OSPurezza:98.62% - 99.89%Colore e forma:SolidPeso molecolare:357.51Pentoxyverine
CAS:Pentoxyverine (Carbetapentan) is an orally available cough suppressant, an antagonist of muscarinic receptor M1 and an agonist of the σ1 receptor.Formula:C20H31NO3Purezza:97.11%Colore e forma:SolidPeso molecolare:333.47Xanomeline tartrate
CAS:Xanomeline tartrate (LY 246708 tartrate) 是 M1和 M4 mAChR 激动剂，具有抗精神病样活性，可改善认知，可用于研究精神分裂症和阿尔茨海默病。Formula:C18H29N3O7SPurezza:99.19% - 99.99%Colore e forma:SolidPeso molecolare:431.5Pipecuronium bromide
CAS:Pipecuronium bromide (RGH-1106) is an nAChR antagonist that also acts as a non-depolarising steroidal neuromuscular blocker that causes muscle relaxation.Formula:C35H62Br2N4O4Purezza:>99.99%Colore e forma:PowderPeso molecolare:762.7Monepantel
CAS:Monepantel (AAD1566) is an organic anthelmintic and an antagonist of nAChRs from roundworms and esophageostomy.Formula:C20H13F6N3O2SPurezza:99.83%Colore e forma:White PowderPeso molecolare:473.39Varenicline
CAS:Varenicline (CP 526555) is a selective partial agonist of the α4β2 nAChR and a full agonist of the α3β4 nAChR and α7 nAChR.Formula:C13H13N3Purezza:99.76%Colore e forma:SolidPeso molecolare:211.26Atropine hydrobromide
CAS:Atropine hydrobromide is a biochemical.Formula:C17H24BrNO3Colore e forma:SolidPeso molecolare:370.28Pyrantel
CAS:Pyrantel: Nicotinic agonist; causes spastic paralysis in nematodes by depolarizing block.Formula:C11H14N2SPurezza:98%Colore e forma:Crystals From Methanol Yellowish Crystalline PowderPeso molecolare:206.31Anatabine dicitrate
Anatabine dicitrate is a tobacco alkaloid that can cross the blood-brain barrier.Formula:C22H28N2O14Purezza:98%Colore e forma:SolidPeso molecolare:544.46Flavoxate
CAS:<p>Flavoxate is an anticholinergic with antimuscarinic effects.</p>Formula:C24H25NO4Colore e forma:SolidPeso molecolare:391.46(±)-Atropine-d3 (N-methyl-d3)
CAS:(±)-Atropine-d3 (N-methyl-d3) is a deuterated compound of (±)-Atropine. (±)-Atropine has a CAS number of 51-55-8. Atropine Sulfate is the sulfate salt of atropine, a naturally-occurring alkaloid isolated from the plant Atropa belladonna. Atropine functions as a sympathetic, competitive antagonist of muscarinic cholinergic receptors, thereby abolishing the effects of parasympathetic stimulation.Formula:C17H20D3NO3Peso molecolare:292.39Diphenidol
CAS:<p>Diphenidol, a muscarinic antagonist, is employed as an antivertigo and antiemetic agent.</p>Formula:C21H27NOColore e forma:Needles From Petroleum Ether SolidPeso molecolare:309.45VU0029767
CAS:<p>VU0029767 is an allosteric enhancer of the M1 muscarinic receptor, capable of modulating the receptor's activity. This compound enhances M1 receptor activity by increasing agonist affinity. However, VU0029767 demonstrates distinct characteristics from other compounds, particularly under varying experimental conditions such as its interaction with mutated M1 receptors and its effects on downstream signaling pathways.</p>Formula:C21H21N3O3Colore e forma:SolidPeso molecolare:363.41Catestatin
CAS:Non-competitive inhibitor of nicotinic receptors; blocks cationic signalling and catecholamine release; stimulates histamine release. IC50 ~200-250nM.Formula:C107H173N37O26SPurezza:98%Colore e forma:SolidPeso molecolare:2425.84N-Biotinyl p-aminophenyl arsenic acid
CAS:N-Biotinyl p-aminophenyl arsenic acid is a bifunctional reagent that binds to streptavidin and disulfide compounds. It diminishes the binding sites of rbungarotoxin on reduced nicotinic receptors with an IC50 ranging from 10-300 nM, thus shielding the receptors from irreversible alkylation by bromoacetylcholine.Formula:C16H22AsN3O4SColore e forma:SolidPeso molecolare:427.35Phenglutarimide hydrochloride
CAS:Phenglutarimide hydrochloride is an anticholinergic. It is used as an antiparkinsonian agent.Formula:C17H25ClN2O2Colore e forma:SolidPeso molecolare:324.85Aprofene
CAS:<p>Aprofene blocks acetylcholine receptors, used for peptic ulcers, endarteritis, cholecystitis, and colitis.</p>Formula:C21H27NO2Colore e forma:SolidPeso molecolare:325.44Dianicline dihydrochloride
CAS:Dianicline dihydrochloride is a partial agonist of α4β2 nicotinic acetylcholine receptor. It increases cessation rates in a dose-dependent manner.Formula:C13H16N2OPurezza:98%Colore e forma:SolidPeso molecolare:216.28
