AChR
Gli inibitori del recettore dell'acetilcolina (AChR) sono composti che bloccano l'attività dei recettori dell'acetilcolina, fondamentali per la neurotrasmissione nei sistemi nervoso centrale e periferico. Gli AChR svolgono un ruolo cruciale nella contrazione muscolare, nella memoria e nelle funzioni cognitive. Gli inibitori degli AChR vengono utilizzati per studiare condizioni come la miastenia grave, l'Alzheimer e altri disturbi neurologici. Modulando l'attività degli AChR, questi inibitori possono aiutare a svelare le complessità della segnalazione colinergica nel cervello. Presso CymitQuimica, offriamo una gamma di inibitori degli AChR per supportare la tua ricerca in neuroscienze, farmacologia e malattie neurodegenerative.
Trovati 617 prodotti di "AChR"
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Biperiden lactate
CAS:<p>Biperiden lactate is a biochemical.</p>Formula:C24H35NO4Colore e forma:SolidPeso molecolare:401.54AN317
CAS:AN317 is a selective agonist for the nicotinic acetylcholine receptor (nAChR) containing α6β2, with dissociation constants (Ki) of 6.2 nM and 4.1 nM for the α6/α3β2β3 and α4β2 receptor subtypes, respectively. It induces dopamine release in rat striatal synaptosomes, enhances the activity of dopaminergic neurons in the substantia nigra, and exhibits protective effects against the dopaminergic neurotoxin MPP+ in rat neurons. AN317 also demonstrates favorable pharmacokinetic properties in rats and permeability across the blood-brain barrier (BB).Formula:C13H19N3Colore e forma:SolidPeso molecolare:217.31Azacyclonol hydrochloride
CAS:Azacyclonol hydrochloride can be used in the treatment of chronic schizophrenia.Formula:C18H22ClNOColore e forma:Off White Crystalline PowderPeso molecolare:303.83Oxantel
CAS:<p>Oxantel is a fumarate reductase inhibitor with anthelmintic activity.</p>Formula:C13H16N2OPurezza:98%Colore e forma:SolidPeso molecolare:216.28Sulindac sulfide
CAS:Sulindac sulfide: NSAID targeting COX-1, inhibits Ras-Raf-1 and gamma-secretase (IC50: 20.2 μM), active sulinic acid metabolite.Formula:C20H17FO2SPurezza:99.35%Colore e forma:SolidPeso molecolare:340.41BTM-1086
CAS:BTM-1086 is a potent gastric secretory inhibitor and an anti-ulcer agent.Formula:C21H25N3OSPurezza:98%Colore e forma:SolidPeso molecolare:367.51CP-601932
CAS:CP-601932 (free base) is a selective base α( 4) β( 2) Nicotinic acetylcholine receptor agonist.Formula:C12H12F3NColore e forma:SolidPeso molecolare:227.23Eucatropine
CAS:Eucatropine, an anticholinergic agent, acts as a potent inhibitor of the muscarinic acetylcholine receptor (mAChR) with an IC 50 value of 0.583 μM.Formula:C17H25NO3Colore e forma:SolidPeso molecolare:291.39Thiochrome
CAS:Thiochrome is a selective enhancer of M4 muscarinic receptor of acetylcholine (ACh) affinity.Formula:C12H14N4OSPurezza:98%Colore e forma:SolidPeso molecolare:262.33GAT107
CAS:GAT107, a strong α7 nicotinic receptor modulator, aids inflammation and neuropathic pain in mice.Formula:C18H17BrN2O2SPurezza:99.33%Colore e forma:SolidPeso molecolare:405.31VU0090157
CAS:VU0090157, a novel allosteric potentiators of M1 muscarinic receptor, may provide novel treatments for schizophrenia and Alzheimer's disease.Formula:C19H21N3O7Purezza:98%Colore e forma:SolidPeso molecolare:403.39S-(+)-Mecamylamine hydrochloride
CAS:Dexmecamylamine( TC-5214, NIH-11008) is used as a nicotinic channel modulator with antidepressant activity.Formula:C11H22ClNColore e forma:SolidPeso molecolare:203.75T761-0184
CAS:T761-0184 is a potent antagonist of α7 nicotinic receptor (nAChR) [1].Formula:C16H20FN3OColore e forma:SolidPeso molecolare:289.35Revatropate
CAS:Revatropate, a selective muscarinic antagonist, is an antimuscarinic drug.Formula:C19H27NO4SColore e forma:SolidPeso molecolare:365.49Rispenzepine
CAS:Rispenzepine, a novel mAChRs M1/M3 antagonist, treats immune, infections, and respiratory issues.Formula:C19H20N4O2Purezza:98%Colore e forma:SolidPeso molecolare:336.39SCH 57790
CAS:SCH 57790: selective muscarinic M2 blocker, boosts acetylcholine & cognition, may treat Alzheimer's.Formula:C25H31N3O2SPurezza:99.12% - 99.69%Colore e forma:SolidPeso molecolare:437.6Tarafenacin
CAS:Tarafenacin is a highly selective M3 muscarinic receptor antagonist (Ki= 0.19 nM), ~200 fold selectivity over the M2 receptor.Formula:C21H20F4N2O2Purezza:98%Colore e forma:SolidPeso molecolare:408.39Milameline
CAS:Milameline is a muscarinic receptor agonist that improves cognition.Formula:C8H14N2OColore e forma:SolidPeso molecolare:154.21Biricodar dicitrate
CAS:Biricodar dicitrate (VX-710) is a potent MDR inhibitor with no anticancer activity and can be used to study prostate cancer.Formula:C46H57N3O21Purezza:97.78% - 99.78%Colore e forma:SolidPeso molecolare:987.95Sofiniclin
CAS:Sofiniclin (ABT 894) is an agonist of nicotinic acetylcholine receptor (nAChR). It is used for the research for attention-deficit/hyperactivity disorder (ADHD).Formula:C10H11Cl2N3Purezza:98%Colore e forma:SolidPeso molecolare:244.12SR 16584
CAS:α3β4 nAChR antagonistFormula:C17H22N2OPurezza:99.84%Colore e forma:SolidPeso molecolare:270.37Bibn 99
CAS:<p>Bibn 99, a lipophilic and selective muscarinic M2 receptor antagonist, has applications in cognitive performance and Alzheimer's Disease.</p>Formula:C31H42ClN5O3Colore e forma:SolidPeso molecolare:568.15VU 6008667
CAS:VU 6008667 is a selective negative allosteric M5 NAM modulator (IC50s: 1.2 μM and 1.6 μM for human M5 and rat M5, respectively).Formula:C24H17ClF2N2O2Purezza:98%Colore e forma:SolidPeso molecolare:438.85Rivanicline
CAS:Rivanicline is a selective α4β2 nicotinic receptor agonist (Ki=26 nM), with >1,000x less affinity for α7 receptors.Formula:C10H14N2Purezza:98%Colore e forma:SolidPeso molecolare:162.23Rapacuronium bromide
CAS:Rapacuronium bromide is an allosteric muscarinic acetylcholine receptor (mAChR) modulator.Formula:C37H61BrN2O4Purezza:98%Colore e forma:SolidPeso molecolare:677.8ML375
CAS:ML375 is a potent, selective and CNS penetrant M5 negative allosteric modulator (NAM).Formula:C23H15ClF2N2O2Colore e forma:SolidPeso molecolare:424.83Sch412348
CAS:Sch412348: potent A2A receptor antagonist, Ki=0.6 nM, >1000-fold selectivity vs. other adenosine receptors.Formula:C22H21F2N9OPurezza:98%Colore e forma:SolidPeso molecolare:465.46CP-601927
CAS:CP-601927 is a nicotinic acetylcholine receptor (NACHR) agonist with permeability, high affinity, and selectivity.Formula:C12H12F3NColore e forma:SolidPeso molecolare:227.23Arecaidine propargyl ester tosylate
CAS:Arecaidine propargyl ester tosylate is a muscarinic receptor agonist.Formula:C17H21NO5SPurezza:98%Colore e forma:SolidPeso molecolare:351.42VMY-2-95
CAS:VMY-2-95 is an α4β2 nicotinic acetylcholine receptors (nAChRs) selective desensitizer.Formula:C17H16N2OColore e forma:SolidPeso molecolare:264.32RJR 2429 dihydrochloride
CAS:nAChR agonist that displays selectivity for α4β2Formula:C12H18Cl2N2Purezza:98%Colore e forma:SolidPeso molecolare:261.19J 104129 fumarate
CAS:M3 muscarinic receptor antagonistFormula:C24H36N2O2Purezza:98%Colore e forma:SolidPeso molecolare:384.55Alvameline maleate
CAS:Alvameline maleate is used as a Partial M1 Agonist and M2/M3 Antagonist.Formula:C13H19N5O4Colore e forma:SolidPeso molecolare:309.32Vinconate
CAS:Vinconate is an indolonaphthyridine derivative and can stimulate the muscarinic acetylcholine receptor.Formula:C18H20N2O2Purezza:98%Colore e forma:SolidPeso molecolare:296.36AT-1001
CAS:AT-1001 is an α3β4 nAChR partial agonist reducing nicotine relapse and withdrawal with negligible impact on food response and dopamine release.Formula:C15H21BrN2Colore e forma:SolidPeso molecolare:309.24PD-102807
CAS:PD-102807 is a selective and competitive M4 muscarinic receptor antagonist for Parkinson's disease research, inhibit airway smooth muscle (ASM) contraction.Formula:C23H24N2O4Purezza:98.90%Colore e forma:SolidPeso molecolare:392.45Rivanicline oxalate
CAS:Rivanicline oxalate is an agonist of neuronal nicotinic receptor, showing high selectivity for the α4β2 subtype (Ki=26 nM).Formula:C12H16N2O4Purezza:98%Colore e forma:SolidPeso molecolare:252.27Bradanicline HCl
CAS:Bradanicline(TC-5619) is the agonist of Alpha-7 Nicotinic Receptor.Formula:C22H24ClN3O2Colore e forma:SolidPeso molecolare:397.9S 24795
CAS:S 24795 (Catestatin acetate(142211-96-9 free base)) is an α7 nAChR partial agonist.Formula:C14H13BrINOPurezza:99.934%Colore e forma:SolidPeso molecolare:418.07DREADD agonist 21 dihydrochloride
CAS:DREADD agonist 21 dihydrochloride is a potent human muscarinic acetylcholine M3 receptors ( hM3Dq ) agonist with EC 50 of 1.7 nM [1].Formula:C17H20Cl2N4Purezza:98%Colore e forma:SolidPeso molecolare:351.27BPIPP
CAS:guanylyl cyclase (GC) and adenylyl cyclase (AC) inhibitorFormula:C22H16BrN3O3Purezza:98%Colore e forma:SolidPeso molecolare:450.28Procyclidine
CAS:Procyclidine is an anticholinergic, muscarinic and NMDA antagonist used in Parkinson's and psychiatric disorder studies.Formula:C19H29NOColore e forma:SolidPeso molecolare:287.44Oxybutynin R-isomer HCl
CAS:Aroxybutynin, R-isomer of oxybutynin, is a muscarinic antagonist with antispasmodic effects on bladder muscle, weaker than atropine.Formula:C22H32ClNO3Colore e forma:SolidPeso molecolare:393.95VU0455691
CAS:VU0455691 is a selective M1 Muscarinic Receptor Allosteric Modulators.Formula:C24H25N5O3SPurezza:98%Colore e forma:SolidPeso molecolare:463.55Ambutonium bromide
CAS:Ambutonium bromide is an antagonist of acetylcholine.Formula:C20H27BrN2OPurezza:98%Colore e forma:SolidPeso molecolare:391.35(±)-Muscarine chloride
CAS:(±)-Muscarine chloride is the racemate of Muscarine chloride. Muscarine is a prototypical agonist for the muscarinic acetylcholine receptor [1] [2].Formula:C9H20ClNO2Colore e forma:SolidPeso molecolare:209.71Methapyrilene
CAS:Methapyrilene is a histamine H1 antagonist with sedative action.Formula:C14H19N3SColore e forma:Liquid Physical Description Clear Colorless Liquid (Ntp 1992)Peso molecolare:261.39Milameline hydrochloride
CAS:Milameline hydrochloride is a Muscarinic receptor agonist.Formula:C8H15ClN2OPurezza:98%Colore e forma:SolidPeso molecolare:190.67Cycrimine
CAS:Cycrimine: oral M1 mAChR blocker, lowers acetylcholine, antispasmodic, for Parkinson's and mental disorder studies.Formula:C19H29NOColore e forma:SolidPeso molecolare:287.44Parapenzolate bromide
CAS:Parapenzolate bromide is an orally active mAChR antagonist. parapenzolate bromide is an anticholinergic and antitussive agent.Formula:C21H26BrNO3Colore e forma:SolidPeso molecolare:420.347
