AChR
Gli inibitori del recettore dell'acetilcolina (AChR) sono composti che bloccano l'attività dei recettori dell'acetilcolina, fondamentali per la neurotrasmissione nei sistemi nervoso centrale e periferico. Gli AChR svolgono un ruolo cruciale nella contrazione muscolare, nella memoria e nelle funzioni cognitive. Gli inibitori degli AChR vengono utilizzati per studiare condizioni come la miastenia grave, l'Alzheimer e altri disturbi neurologici. Modulando l'attività degli AChR, questi inibitori possono aiutare a svelare le complessità della segnalazione colinergica nel cervello. Presso CymitQuimica, offriamo una gamma di inibitori degli AChR per supportare la tua ricerca in neuroscienze, farmacologia e malattie neurodegenerative.
Trovati 617 prodotti di "AChR"
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VU6005806
CAS:VU6005806 is a potent M4 PAM with EC50s: 94 nM (human), 28 nM (rat), 87 nM (dog), 68 nM (cyno); studied for neuropsychiatric disorders.Formula:C17H16F3N7O2SPurezza:98%Colore e forma:SolidPeso molecolare:439.41VU6016235
CAS:VU6016235 is a structurally unique, orally available, and highly selective tricyclic M4 muscarinic acetylcholine receptor positive allosteric modulator.Formula:C21H22N4OSColore e forma:SolidPeso molecolare:378.49LY593093
CAS:LY593093 is a selective partial orthosteric agonist of M1 muscarinic acetylcholine receptor.Formula:C32H30FN3O2Purezza:98%Colore e forma:SolidPeso molecolare:507.6UB 165
CAS:Subtype-selective nicotinic agonistFormula:C13H15ClN2Purezza:98%Colore e forma:SolidPeso molecolare:234.721,9-Dideoxyforskolin
CAS:The compound is an inactive analog of forskolin(an adenylyl cyclase activator).Formula:C22H34O5Purezza:98%Colore e forma:SolidPeso molecolare:378.5Metoquizine
CAS:Metoquizine is an anticholinergic compound. It is a muscarinic acetylcholine receptor antagonist that has been used to treat ulcers.Formula:C22H27N5OPurezza:98%Colore e forma:SolidPeso molecolare:377.48(+)-Cevimeline hydrochloride hemihydrate
(+)-Cevimeline HCl hemihydrate is a muscarinic agonist for dry mouth in Sjogren's with rapid absorption, differing metabolism in species.Formula:C10H19ClNO1·5SPurezza:98%Colore e forma:SolidPeso molecolare:244.78Acetylethylcholine mustard hydrochloride
CAS:Acetylethylcholine mustard hydrochloride is a choline acetyl-transferase inhibitor that decreases muscle contraction frequency by inhibiting the synthesis of acetyl-beta-methylcholine (Ach), with a half-maximal inhibitory concentration (IC50) of 1.22 mM. It serves as an irreversible ligand for the high-affinity choline transport system and functions as a specific presynaptic long-acting cholinergic toxin. Additionally, acetylethylcholine mustard hydrochloride is a precursor to the ethylcholine mustard aziridinium ion.Formula:C8H17Cl2NO2Peso molecolare:230.132Lu 26-046
CAS:Lu 26-046 is a muscarinic receptor agonist.Formula:C10H12N2OSColore e forma:SolidPeso molecolare:208.28(-)-Cevimeline hydrochloride hemihydrate
(-)-Cevimeline HCl hemihydrate, a muscarinic agonist, treats Sjogren's xerostomia. Quick absorption, species-dependent metabolism.Formula:C10H19ClNO1·5SPurezza:98%Colore e forma:SolidPeso molecolare:244.78nAChR antagonist 1
CAS:Compound B15, a potent α7 nAChR antagonist, IC50 = 3.3 μM, promising for research on schizophrenia, Alzheimer's, and inflammation.Formula:C19H22N4O2Colore e forma:SolidPeso molecolare:338.4Dihydro-β-erythroidine
CAS:Dihydro-β-erythroidine, a competitive nicotinic receptor antagonist, effectively blocks the discriminative stimulus properties and inhibits the anxiolyticFormula:C16H21NO3Colore e forma:SolidPeso molecolare:275.34AChE/BChE-IN-10
CAS:<p>AChE/BChE-IN-10 inhibits AChE/BChE (IC50: 0.176/0.47 μM), crosses the blood-brain barrier, and prevents Aβ-aggregation.</p>Formula:C26H30N2O2Purezza:99.55% - 99.88%Colore e forma:SoildPeso molecolare:402.53VU6000918
CAS:<p>VU6000918 is a positive allosteric modulator that targets the muscarinic acetylcholine receptor subtype M4. It exhibits a half maximal effective concentration (EC50) of 19 nM for the human M4 receptor.</p>Formula:C18H17F2N5OSColore e forma:SolidPeso molecolare:389.42Lupinine
CAS:<p>Lupinine is an alkaloid capable of counteracting ethanol anesthesia. Lupinine is an AChE and BChE inhibitor and potential CD69 activator found in species of Loranthus, Calia, and Lupinus. It may also inhibit heparin.</p>Formula:C10H19NOPurezza:99.95%Colore e forma:SolidPeso molecolare:169.26Oxitropium Bromide
CAS:Oxitropium bromide, a mAChR blocker, treats asthma and COPD as an anticholinergic bronchodilator.Formula:C19H26BrNO4Purezza:98%Colore e forma:SolidPeso molecolare:412.32Ref: TM-T16417
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