Proteasi/Proteasoma
Gli inibitori delle proteasi e del proteasoma sono composti che bloccano l'attività delle proteasi e del proteasoma, che sono coinvolti nella degradazione e nel turnover delle proteine. Questi inibitori sono fondamentali per studiare la regolazione dell'omeostasi proteica, il controllo del ciclo cellulare e l'apoptosi. Gli inibitori delle proteasi e del proteasoma vengono anche utilizzati nel trattamento di malattie come il cancro, dove la degradazione anomala delle proteine svolge un ruolo nella progressione della malattia. Inibendo le proteasi o il proteasoma, questi composti possono indurre la morte cellulare nelle cellule tumorali e sono strumenti critici sia per la ricerca di base che per lo sviluppo terapeutico. Presso CymitQuimica, offriamo una vasta gamma di inibitori delle proteasi e del proteasoma di alta qualità per supportare la tua ricerca in biochimica, biologia cellulare e sviluppo di farmaci.
Sottocategorie di "Proteasi/Proteasoma"
- Acetil-CoA carbossilasi(36 prodotti)
- Cisteina proteasi(110 prodotti)
- DPP-4(20 prodotti)
- Glutaminasi(45 prodotti)
- Proteasi HIV(506 prodotti)
- PAI-1(26 prodotti)
- Inibitori della proteasi(50 prodotti)
- Ricettore attivato dalla proteasi(54 prodotti)
- Proteasoma(95 prodotti)
- Proteasi serina(55 prodotti)
- p97(15 prodotti)
Mostrare 3 più sottocategorie
Trovati 1095 prodotti di "Proteasi/Proteasoma"
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Melagatran
CAS:<p>Melagatran is an orally available, direct synthetic thrombin inhibitor that does not require endogenous cofactors other than thrombin.Cost-effective and quality-assured.</p>Formula:C22H31N5O4Purezza:98.29% - >99.99%Colore e forma:SolidPeso molecolare:429.51PG-116800
CAS:PG-116800 (PG-530742) is a matrix metalloproteinase (MMP) inhibitor. PG-116800 can be used in studies about the treatment of osteoarthritis.Formula:C24H27N3O7SPurezza:98.03% - 99.66%Colore e forma:SolidPeso molecolare:501.55BDCRB
BDCRB disrupts HCMV DNA maturation by altering terminase cleavage, extending packaging 30 kb until second site.Formula:C12H11BrCl2N2O4Purezza:99.41% - 99.85%Colore e forma:SoildPeso molecolare:398.04Sovaprevir
CAS:Sovaprevir is a non-structural 3 (NS3) protease inhibitor with antiviral activity for the treatment of HCV infection.Formula:C43H53N5O8SPurezza:99.89%Colore e forma:SolidPeso molecolare:799.97Ref: TM-T28830
1mg266,00€5mg655,00€10mg934,00€25mg1.388,00€50mg1.872,00€100mg2.517,00€1mL*10mM (DMSO)1.035,00€Setrobuvir
CAS:Setrobuvir (ANA-598) is an orally active non-nucleoside HCV NS5B polymerase inhibitor with inhibitory effects on de novo RNA synthesis and primer extension withFormula:C25H25FN4O6S2Purezza:99.95% - 99.97%Colore e forma:SolidPeso molecolare:560.62Ref: TM-T28762
1mg229,00€5mg570,00€10mg812,00€25mg1.216,00€50mg1.663,00€100mg2.242,00€500mg4.494,00€1mL*10mM (DMSO)737,00€BMS-488043
CAS:BMS-488043 is a novel and unique oral small molecule HIV fusion inhibitor that inhibits the attachment of Human Immunodeficiency Virus type 1 (HIV-1) to CD4(+)Formula:C22H22N4O5Purezza:99.95%Colore e forma:SolidPeso molecolare:422.43UPGL00004
CAS:UPGL00004: potent GAC inhibitor, IC50=29 nM, Kd=27 nM, suppresses triple-negative breast cancer cell growth.Formula:C25H26N8O2S2Purezza:97.93%Colore e forma:SolidPeso molecolare:534.66BAY-43-9695
CAS:BAY-43-9695 is a non-nucleoside compound with anti-human cytomegalovirus (HCMV) activity. It is the major metabolite of BAY-38-4766.Formula:C22H25N3O4SPurezza:99.50% - 99.98%Colore e forma:SolidPeso molecolare:427.52MK-8325
CAS:MK-8325 is a potent and orally available HCV NS5A inhibitor with replicative activity against a wide range of genotypes.MK-8325 has demonstrated bioavailabilityFormula:C43H54Cl2F2N8O6SiPurezza:99.61%Colore e forma:SolidPeso molecolare:915.93BILB-1941
CAS:BILB-1941 (BILB-1941ZW) is an inhibitor of HCV NS5B polymerase and can be used in studies about HCV infection.Formula:C34H34N4O4Purezza:99.51% - 99.65%Colore e forma:SolidPeso molecolare:562.66Ref: TM-T26815
1mg313,00€5mg758,00€10mg1.035,00€25mg1.568,00€50mg2.118,00€100mg2.783,00€1mL*10mM (DMSO)1.103,00€NP-313
CAS:NP-313 (NSC-4264) is a potent antithrombotic that blocks platelet aggregation via thromboxane A2 synthesis inhibition and targets SOCC-mediated Ca2+ efflux.Formula:C12H8ClNO3Purezza:99.92%Colore e forma:SolidPeso molecolare:249.652'-C-Methyladenosine
CAS:<p>2'-C-Methyladenosine from C. renalis inhibits HCV, NS5B RNA synthesis (IC50: 0.3, 1.9µM), and LRV1 in L. guyanensis, L. braziliensis.</p>Formula:C11H15N5O4Purezza:99.85%Colore e forma:SolidPeso molecolare:281.27KM-023
CAS:KM-023 is a new second-generation non-nucleoside reverse transcriptase inhibitor for the study of human immunodeficiency virus (HIV) type 1 infection.Formula:C18H19N3O3Purezza:99.03% - 99.47%Colore e forma:SolidPeso molecolare:325.36Ref: TM-T67804
1mg150,00€5mg361,00€10mg542,00€25mg870,00€50mg1.188,00€100mg1.596,00€500mg3.202,00€1mL*10mM (DMSO)359,00€MMP-2/MMP-9 Inhibitor I
CAS:<p>MMP-2/MMP-9-IN-1: oral IV collagenase inhibitor; IC50: 0.24 μM (MMP-9), 0.31 μM (MMP-2); targets cancer.</p>Formula:C21H19NO4SPurezza:99.74%Colore e forma:SolidPeso molecolare:381.44Tyrosinase-IN-2
CAS:Tyrosinase-IN-2, a potent tyrosinase inhibitor, may help in skin lightening and food preservation research.Formula:C8H8N4O2SPurezza:99.78%Colore e forma:SolidPeso molecolare:224.24Ref: TM-T60278
5mg48,00€10mg71,00€25mg135,00€50mg212,00€100mg340,00€200mg467,00€1mL*10mM (DMSO)49,00€Gemigliptin
CAS:Gemigliptin (LC15-0444) is a potent dipeptidyl peptidase-4 (DPP-4) inhibitor(KD : 7.25 nM.)Formula:C18H19F8N5O2Purezza:99.72%Colore e forma:SolidPeso molecolare:489.36Ref: TM-T7369
2mg40,00€5mg60,00€10mg87,00€25mg157,00€50mg259,00€100mg406,00€500mg920,00€1mL*10mM (DMSO)88,00€Etarotene
CAS:Etarotene (Arotinoid ethyl sulphone) is an ethylsulfonyl derivative of aloe acid with differentiation-inducing and potentially antitumor activity.Etarotene is aFormula:C25H32O2SPurezza:99.58% - 99.98%Colore e forma:SolidPeso molecolare:396.59HIV-1 integrase inhibitor 8
CAS:<p>HIV-1 integrase inhibitor 8 is an inhibitor of HIV-1 integrase. Integration is a required step in HIV replication [1].</p>Formula:C21H24O2Purezza:98.91%Colore e forma:SolidPeso molecolare:308.41AGPS-IN-2i
CAS:AGPS-IN-2i inhibits alkylglycerol phosphate synthase, affecting ether lipid metabolism and reducing cancer cell migration and proliferation.Formula:C18H17F2N3O2Purezza:98.92%Colore e forma:SolidPeso molecolare:345.34Ref: TM-T69685
1mg74,00€5mg188,00€10mg311,00€25mg525,00€50mg747,00€100mg1.017,00€1mL*10mM (DMSO)154,00€UK-396082
CAS:UK-396082 is a TAFI inhibitor that inhibits Carboxypeptidase B and can be used in the study of thrombosis, atherosclerosis, cancer and fibrotic conditions.Formula:C12H21N3O2Purezza:99.89%Colore e forma:SolidPeso molecolare:239.31Emivirine
CAS:Emivirine (MKC-442) is a potent and selective nonnucleoside reverse transcriptase inhibitor of human immunodeficiency virus type 1.Formula:C17H22N2O3Purezza:99.8%Colore e forma:SolidPeso molecolare:302.37Z-DEVD-CMK
CAS:Z-DEVD-CMK irreversibly inhibits various cathepsins in vitro [1].Formula:C27H35ClN4O12Colore e forma:SolidPeso molecolare:643.04AZD-9819
CAS:AZD-9819 is a neutrophil elastase (HNE) inhibitor applicable for research into chronic obstructive pulmonary disease (COPD).Formula:C25H19F3N6O2Purezza:100% - 99.18%Colore e forma:SolidPeso molecolare:492.45H-Gly-Pro-Hyp-OH acetate
CAS:H-Gly-Pro-Hyp-OH, a peptide dipeptidyl peptidase 4 (DPP-4) inhibitor with an inhibition concentration (IC50) of 2.51 mM, effectively hinders the activity of the DPP-4 enzyme.Formula:C12H19N3O5C2H4O2Colore e forma:SolidPeso molecolare:345.35(Rac)-Neurodegenerative Disorder-Targeting Compound 1
CAS:(Rac)-Neurodegenerative Disorder-Targeting Compound 1 is a calpain inhibitor.Formula:C28H28N4O4Colore e forma:SolidPeso molecolare:484.55Ro 31-9790
CAS:Ro 31-9790 is a synthetic inhibitor of metalloproteinase (MMP).Formula:C15H29N3O4Purezza:98%Colore e forma:SolidPeso molecolare:315.41Thrombin inhibitor 1
CAS:<p>Thrombin inhibitor 1 is a potent inhibitor of thrombin (Ki: 0.66 nM, 2xaPTT=0.43 μM).</p>Formula:C22H20Cl2F2N4O3Purezza:98%Colore e forma:SolidPeso molecolare:497.32AA74-1
CAS:AA74-1 is a potent, selective APEH inhibitor that significantly enhances T-cell proliferation by inhibiting APEH activity [1].Formula:C16H28N4O2Purezza:98%Colore e forma:SolidPeso molecolare:308.42JW 480
CAS:JW480 is a potent and selective inhibitor of KIAA1363, a serine hydrolase enzyme.Formula:C22H23NO2Purezza:99.72%Colore e forma:SolidPeso molecolare:333.42Ref: TM-T22883
2mg38,00€5mg51,00€10mg84,00€25mg169,00€50mg273,00€100mg439,00€200mg620,00€1mL*10mM (DMSO)60,00€Flovagatran sodium
CAS:Flovagatran sodium, a thrombin inhibitor, is used potentially for the treatment of thrombosis.Formula:C27H36BN3NaO7Purezza:98%Colore e forma:SolidPeso molecolare:548.4BAY-320
CAS:BAY-320 is a Bub1 inhibitor. With an IC50 of 680 nM for human Bub1 in the presence of 2 mM ATP.Formula:C26H26F2N6O2Purezza:98%Colore e forma:SolidPeso molecolare:492.52SQ 32056
CAS:SQ 32056 is a cathepsin E inhibitor.Formula:C37H56N4O5Purezza:98%Colore e forma:SolidPeso molecolare:636.86BMS-189664 HCl
CAS:BMS-189664 HCl is a selective and orally active thrombin active site inhibitor.Formula:C22H35ClN6O4SPurezza:98%Colore e forma:SolidPeso molecolare:515.07Tyropeptin A-4
CAS:Tyropeptin A-4 is used as a proteasome inhibitor.Formula:C31H41N3O6Purezza:98%Colore e forma:SolidPeso molecolare:551.67LM-030
CAS:LM-030, also known as BPR277, is a novel inhibitor of kallikrein-related peptidase 7 (KLK7) and epidermal elastase 2 (ELA2).Formula:C46H72N8O12Colore e forma:SolidPeso molecolare:929.11M190S
CAS:M109S is a novel small molecule that shields cells from mitochondria-dependent apoptosis, demonstrating effectiveness both in vitro and in vivo.Formula:C21H21N5O2Purezza:98%Colore e forma:SolidPeso molecolare:375.42NS5A-IN-3
CAS:NS5A-IN-3 is a potent NS5A inhibitor with high efficacy against HCV 1b, good activity on 3a, and strong metabolic stability; superior to daclatasvir.Formula:C44H44N6O8Purezza:98%Colore e forma:SolidPeso molecolare:784.86Azt-pmap
CAS:AZT-PMPA, an aryl phosphate derivative of AZT and a nucleoside analogue, demonstrates anti-HIV activity[1].Formula:C20H25N6O8PPurezza:98%Colore e forma:SolidPeso molecolare:508.42HIV-1 protease-IN-11
CAS:HIV-1 protease-IN-11 (compound 34a), an HIV-1 protease inhibitor, demonstrates potent inhibition with an IC50 of 0.41 nM and maintains substantial efficacyFormula:C26H37N3O5SPurezza:98%Colore e forma:SolidPeso molecolare:503.65HIV-1 protease-IN-8
CAS:HIV-1 protease-IN-8 (compound 34b) is a potent inhibitor of the HIV-1 protease enzyme, exhibiting an IC50 of 0.32 nM.Formula:C25H35N3O5SPurezza:98%Colore e forma:SolidPeso molecolare:489.63HIV-1 protease-IN-7
CAS:HIV-1 protease-IN-7 (compound 16) is an orally active inhibitor of HIV-1 protease, exhibiting an IC50 of 3.52 nM and an EC50 of 37 nM [1].Formula:C68H104N10O12SPurezza:98%Colore e forma:SolidPeso molecolare:1285.68HIV-1 protease-IN-12
CAS:HIV-1 protease-IN-12 (compound 35b) serves as a potent inhibitor of HIV-1 protease, exhibiting an IC50 value of 0.51 nM, and demonstrates efficacy against drug-Formula:C25H35N3O5SPurezza:98%Colore e forma:SolidPeso molecolare:489.63NS5A-IN-2
CAS:NS5A-IN-2, a potent inhibitor, is highly effective against HCV 1b and shows increased activity for GT 3a with good metabolic stability.Formula:C46H45N7O7Purezza:98%Colore e forma:SolidPeso molecolare:807.89NCI-B16
CAS:NCI-B16 is a small-molecule RNA binder that inhibits HCV (hepatitis C virus) replication [1].Formula:C27H26N8O4Colore e forma:SolidPeso molecolare:526.55HIV-1 protease-IN-9
CAS:HIV-1 protease-IN-9 (compound 5b), a potent HIV-1 protease inhibitor, exhibits strong antiviral efficacy with a dissociation constant (K_i) of 0.028 nM and aFormula:C37H41N7O4SPurezza:98%Colore e forma:SolidPeso molecolare:679.83TP0556351
CAS:TP0556351: potent MMP2 inhibitor with 0.2 nM IC50, reduces collagen in pulmonary fibrosis mice.Formula:C50H70N10O16Purezza:98%Colore e forma:SolidPeso molecolare:1067.15HCV-IN-44
CAS:HCV-IN-44 (compound 28) is an inhibitor of the HCV NS5B protein, efficacious in suppressing HCV virus replication and useful for researching HCV infection [1].Formula:C24H26FN3O5SColore e forma:SolidPeso molecolare:487.54(1R,4S)-Yimitasvir diphosphate
CAS:Yimitasvir diphosphate, also known as Emitasvir, is an orally-administered inhibitor of the hepatitis C virus (HCV) nonstructural protein 5A (NS5A).Formula:C49H64N8O14P2Colore e forma:SolidPeso molecolare:1051.03MeOSuc-AAPV-CMK
CAS:MeOSuc-AAPV-CMK (Elastase Inhibitor III) serves as an inhibitor of elastase, as well as cathepsin G and proteinase 3, and impedes leukocyte elastase-mediatedFormula:C22H35ClN4O7Colore e forma:SolidPeso molecolare:502.99Ecallantide
CAS:Ecallantide (DX-88) is a recombinant inhibitor specifically targeting plasma kallikrein, which serves to impede the synthesis of bradykinin.Formula:C305H448N88O91S8Colore e forma:SolidPeso molecolare:7059.88
