DPP-4
Gli inibitori di DPP-4 sono composti che inibiscono la Dipeptidil Peptidasi-4, un enzima coinvolto nell'inattivazione degli ormoni incretinici, che regolano il metabolismo del glucosio. Inibendo la DPP-4, questi composti aiutano a prolungare l'azione degli ormoni incretinici, migliorando la secrezione di insulina e riducendo i livelli di glucosio nel sangue. Gli inibitori di DPP-4 sono ampiamente utilizzati nel trattamento del diabete di tipo 2 e nella ricerca sui disturbi metabolici. Presso CymitQuimica, offriamo inibitori di DPP-4 per supportare la tua ricerca in endocrinologia, gestione del diabete e malattie metaboliche.
Trovati 94 prodotti per "DPP-4".
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Retagliptin Phosphate
CAS:Retagliptin Phosphate (SP 2086) is pharmaceutical composition of DPP-4 inhibitor, for treating type-2 diabetes.Formula:C19H21F6N4O7PPurezza:98.70%Colore e forma:SolidPeso molecolare:562.3568Begelomab
CAS:Begelomab (SAND-26) is a mouse-derived monoclonal antibody targeting DPP-4/CD26. Begelomab can be used to study severe refractory inflammatory myopathies.Purezza:97.8% (SDS-PAGE); 98.3% (SEC-HPLC) - 97.8% (SDS-PAGE); 98.3% (SEC-HPLC)Colore e forma:Transparent LiquidPeso molecolare:146.20 kDa (Predicted)DBPR108
CAS:DBPR108 is an orally bioavailable dipeptide-derived DPP4 inhibitor (IC50: 15 nM) and it has no inhibition on DDP8 and DPP9.Formula:C16H25FN4O2Purezza:99.68%Colore e forma:SolidPeso molecolare:324.3937Denagliptin
CAS:Denagliptin is a small molecule dipeptidyl peptidase IV (DPP-4) inhibitor for the treatment of endocrine Ü metabolic diseases and can be used in the study ofFormula:C20H18F3N3OPurezza:99.12%Colore e forma:SolidPeso molecolare:373.3716Saxagliptin hydrate
CAS:Saxagliptin hydrate (Onglyza hydrate) is a selective and reversible DPP4 inhibitor (IC50: 26 nM; Ki: 1.3 nM).Formula:C18H27N3O3Purezza:99.52%Colore e forma:SolidPeso molecolare:333.4253Trelagliptin
CAS:Trelagliptin (SYR-472) is a highly specific and long-acting DPP-4 inhibitor.Formula:C18H20FN5O2Purezza:98.88%Colore e forma:SolidPeso molecolare:357.3821Fotagliptin
CAS:Fotagliptin is a dipeptidyl peptidase IV inhibitor.Formula:C17H19FN6OColore e forma:SolidPeso molecolare:342.37Linagliptin Methyldimer
CAS:Linagliptin Methyldimer is a potent dipeptidyl peptidase IV inhibitor, IC50=6 pM.Formula:C50H56N16O4Purezza:99.91%Colore e forma:SolidPeso molecolare:945.0844AMG-222
CAS:AMG-222 (ALS-2-0426, ALS-20426) is a DPP-4 inhibitor and may be used in the treatment of type 2 diabetes.Formula:C32H39N9O3Colore e forma:SolidPeso molecolare:597.71(-)-Sitagliptin Carbamoyl Glucuronide
CAS:Minor phase II metabolite of DPP-4 inhibitor sitagliptin, found in rat and dog plasma.Formula:C23H23F6N5O9Colore e forma:SolidPeso molecolare:627.453DPP-4/GPR119 modulator 1
CAS:Orally active DPP-4 inhibitor/GPR119 agonist, Compound 22 lowers glucose, moderate hERG inhibition, IC50 4.9 µM, for diabetes research.Formula:C30H39ClN10O3Colore e forma:SolidPeso molecolare:623.15Sitagliptin fenilalanil hydrochloride
CAS:Sitagliptin fenilalanil hydrochloride is an orally active DPP-4 inhibitor. Sitagliptin fenilalanil hydrochloride is used in diabetes research.Formula:C25H25ClF6N6O2Purezza:98.32%Colore e forma:White SolidPeso molecolare:590.955-Hydroxy saxagliptin hydrochloride
5-Hydroxy saxagliptin hydrochloride is the active metabolite of Saxagliptin and serves as a potent and selective DPP-4 inhibitor. The Ki values for 5-Hydroxy saxagliptin hydrochloride are 2.6 nM in humans and 2.9 nM in cynomolgus monkeys. This compound is applicable in the research of type 2 diabetes.Talabostat isomer mesylate
Talabostat isomer mesylate, a PT100/Val-boroPro variant, is a potent oral DPP-IV inhibitor (Ki: 0.18 nM).Formula:C10H23BN2O6SPurezza:98%Colore e forma:SolidPeso molecolare:310.18SGLT2-IN-6
SGLT2-IN-6 (Compound 101) is an orally active SGLT2 inhibitor with IC₅₀ values of 0.8 nM, 6.7 nM, and 72 nM for SGLT2, SGLT1, and DPP4, respectively. In diabetic rat models, SGLT2-IN-6 controls blood glucose levels and increases active GLP-1 levels. It is suitable for research on type 2 diabetes.HAEGT
CAS:HAEGT is the first N-terminal 1-5 residues of GLP-1 peptide.Formula:C20H31N7O9Purezza:98%Colore e forma:SolidPeso molecolare:513.5016SGLT2-IN-5
SGLT2-IN-5 (Compound 99) is an orally active SGLT2 inhibitor with IC₅₀ values of 0.8 nM for SGLT2, 23 nM for SGLT1, and 58 nM for DPP4. In diabetic rat models, SGLT2-IN-5 effectively regulates blood glucose and increases the levels of active GLP-1. It is suitable for research on type 2 diabetes.Dutogliptin tartrate
CAS:Dutogliptin tartrate is an effective and selective oral dipeptide-peptide-4 (DPP4) inhibitor for the treatment of type 2 diabetes mellitus.Formula:C14H26BN3O9Purezza:98%Colore e forma:SolidPeso molecolare:391.18Ellipyrone A
Ellipyrone A: γ-pyrone macrocycle, inhibits DPP-4 (IC50=0.35mM), α-glucosidase (IC50=0.74mM), α-amylase (IC50=0.59mM).Formula:C25H34O8Colore e forma:SolidPeso molecolare:462.53Camegliptin
CAS:Cameglipti, a dipeptidyl peptidase IV (DPP-4) inhibitor, is used potentially for the treatment of type 2 diabetes.Formula:C20H28FN3O3Colore e forma:SolidPeso molecolare:377.45
