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Ricettore attivato dalla proteasi

Ricettore attivato dalla proteasi

Gli inibitori del Recettore Attivato dalle Proteasi (PAR) sono composti che bersagliano e inibiscono l'attività dei PAR, una famiglia di recettori accoppiati a proteine G attivati dalla scissione proteolitica. Questi recettori svolgono un ruolo in vari processi fisiologici, tra cui la coagulazione, l'infiammazione e la riparazione dei tessuti. Gli inibitori dei PAR sono strumenti preziosi per studiare i meccanismi di questi processi e il loro coinvolgimento in malattie come il cancro, i disturbi cardiovascolari e l'infiammazione cronica. Presso CymitQuimica, offriamo inibitori dei PAR per supportare la tua ricerca nella trasduzione del segnale, risposta immunitaria e scoperta terapeutica.

Trovati 53 prodotti di "Ricettore attivato dalla proteasi"

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  • FLLRN
    Targetmol
    + Info

    FLLRN

    CAS:
    <p>FLLRN is a biologically active peptide serving as a PAR1-specific antagonist.</p>
    Formula:C31H51N9O7
    Colore e forma:Solid
    Peso molecolare:661.79

    Ref: TM-T78545

  • YFLLRNP
    Targetmol
    + Info

    YFLLRNP

    CAS:
    <p>YFLLRNP is a biologically active peptide functioning as a partial agonist of PAR-1, selectively activating the G12/13 signaling pathway.</p>
    Formula:C45H67N11O10
    Colore e forma:Solid
    Peso molecolare:922.08

    Ref: TM-T80235

  • TRAP-5 amide
    Targetmol
    + Info

    TRAP-5 amide

    CAS:
    <p>TRAP-5 amide is a peptide agonist for protease-activated receptor 1 (PAR 1) [1].</p>
    Formula:C30H51N9O6
    Colore e forma:Solid
    Peso molecolare:633.78

    Ref: TM-T80111

  • Logo CymitQuimica
    Targetmol
    + Info

    PAR 4 (1-6) (TFA)

    <p>PAR 4 (1-6) TFA (GYPGQV TFA), a hexapeptide derived from protease-activated receptor 4 (PAR 4), serves as a specific agonist for PAR 4.</p>
    Formula:C28H41N7O9·xC2HF3O2
    Colore e forma:Solid

    Ref: TM-T75904

  • Logo CymitQuimica
    Targetmol
    + Info

    P4pal10 TFA

    <p>P4pal10 TFA, the TFA salt form of P4pal10, serves as an antagonist of the protease-activated receptor 4 (PAR4). This compound inhibits platelet aggregation and thrombin generation induced by tissue factor (TF), exhibiting anticoagulant and antithrombotic activities. Additionally, P4pal10 TFA alleviates carrageenan-induced edema and neutrophil infiltration, and ameliorates damage in rat myocardial ischemia/reperfusion (I/R) models.</p>
    Colore e forma:Odour Solid

    Ref: TM-TP2784

  • TRAP-6 amide TFA
    Targetmol
    + Info

    TRAP-6 amide TFA

    CAS:
    <p>TRAP-6 amide TFA is a PAR-1 thrombin receptor agonist peptide.</p>
    Formula:C36H58F3N11O10
    Colore e forma:Solid
    Peso molecolare:861.922

    Ref: TM-T38887

  • TFLLR-NH2(TFA)
    Targetmol
    + Info

    TFLLR-NH2(TFA)

    CAS:
    <p>TFLLR-NH2 (TFA) is a selective PAR1 agonist with an EC50 of 1.9 μM. EC50: 1.9 μM (PAR1)</p>
    Formula:C33H54F3N9O8
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:761.83

    Ref: TM-TP1334

  • SLIGRL-NH2
    Targetmol
    + Info

    SLIGRL-NH2

    CAS:
    <p>SLIGRL-NH2 (Protease-Activated Receptor-2 Activating Peptide) is a PAR-2 agonist that induces non-histaminergic pruritus.</p>
    Formula:C29H56N10O7
    Purezza:98.29%
    Colore e forma:Solid
    Peso molecolare:656.82

    Ref: TM-TP1046

  • AZ3451
    Targetmol
    + Info

    AZ3451

    CAS:
    <p>AZ3451 is an allosteric antagonist of protease-activated receptor-2 (PAR2, IC50: 23 nM).</p>
    Formula:C30H27BrN4O3
    Purezza:98.12%
    Colore e forma:Solid
    Peso molecolare:571.46

    Ref: TM-TQ0012

  • PAR-2-IN-1
    Targetmol
    + Info

    PAR-2-IN-1

    CAS:
    <p>PAR-2-IN-1 (IUN76750) is a PAR- 2 signaling pathway inhibitor with anti-inflammatory and anticancer effects.</p>
    Formula:C12H14ClN3O2
    Purezza:99.75%
    Colore e forma:Solid
    Peso molecolare:267.71

    Ref: TM-T8917

  • Vorapaxar
    Targetmol
    + Info

    Vorapaxar

    CAS:
    <p>Vorapaxar (MK-5348) (SCH 530348) is an effective and orally active thrombin receptor (PAR-1) antagonist (Ki: 8.1 nM).</p>
    Formula:C29H33FN2O4
    Purezza:98.77% - 99.93%
    Colore e forma:Solid
    Peso molecolare:492.58

    Ref: TM-T7013

  • Vorapaxar sulfate
    Targetmol
    + Info

    Vorapaxar sulfate

    CAS:
    <p>Vorapaxar sulfate (Zontivity) is a potent and orally active thrombin receptor (PAR-1) antagonist.</p>
    Formula:C29H35FN2O8S
    Purezza:99.9% - >99.99%
    Colore e forma:Solid
    Peso molecolare:590.66

    Ref: TM-T3098

  • I-191
    Targetmol
    + Info

    I-191

    CAS:
    <p>I-191 is a potent antagonist of protease-activated receptor 2 (PAR2), inhibits multiple signaling functions in human cancer cells.</p>
    Formula:C23H26FN5O2
    Purezza:99.8%
    Colore e forma:Solid
    Peso molecolare:423.48

    Ref: TM-T7137

  • TRAP-6
    Targetmol
    + Info

    TRAP-6

    CAS:
    <p>TRAP-6 (Thrombin Receptor Activator Peptide 6)(2TFA) is an agonist of protease-activated receptor 1 (PAR1).</p>
    Formula:C34H56N10O9
    Purezza:>99.99%
    Colore e forma:Solid
    Peso molecolare:748.87

    Ref: TM-T7625

  • PAR-4 Agonist Peptide, amide TFA
    Targetmol
    + Info

    PAR-4 Agonist Peptide, amide TFA

    CAS:
    <p>PAR-4 agonist peptide doesn't affect PAR-1/PAR-2; blocked by PAR-4 antagonist.</p>
    Formula:C36H49F3N8O9
    Purezza:99.72%
    Colore e forma:Solid
    Peso molecolare:794.82

    Ref: TM-TP1065

  • Protease-Activated Receptor-1, PAR-1 Agonist acetate
    Targetmol
    + Info

    Protease-Activated Receptor-1, PAR-1 Agonist acetate

    <p>PAR-1 Agonist acetate is a selective PAR-1 agonist that mimics thrombin action.</p>
    Formula:C37H62N10O11
    Purezza:98.1800%
    Colore e forma:Solid
    Peso molecolare:822.95

    Ref: TM-T38836L

  • PAR-2 Activating Peptide acetate
    Targetmol
    + Info

    PAR-2 Activating Peptide acetate

    <p>PAR-2 Activating Peptide acetate (SLIGRL-NH2 acetate) is an agonist of Protease-Activated Receptor-2 (PAR-2).</p>
    Formula:C31H60N10O9
    Purezza:98.5% - 99.92%
    Colore e forma:Solid
    Peso molecolare:716.88

    Ref: TM-TP1046L

  • AC-55541
    Targetmol
    + Info

    AC-55541

    CAS:
    <p>AC-55541 (AOB2796), a PAR2 agonist, activates PAR2 in cellular proliferation assays, phosphatidylinositol hydrolysis assays, and Ca(2+) mobilization assays.</p>
    Formula:C25H20BrN5O3
    Purezza:98% - 99.33%
    Colore e forma:Solid
    Peso molecolare:518.36

    Ref: TM-T2370

  • LRGILS-NH2 acetate
    Targetmol
    + Info

    LRGILS-NH2 acetate

    <p>LRGILS-NH2 acetate is a PAR-2-inactive reversed peptide.</p>
    Formula:C29H56N10O7
    Purezza:96.65%
    Colore e forma:Solid
    Peso molecolare:656.82

    Ref: TM-T22933L

  • FSLLRY-NH2 TFA(245329-02-6 free base)
    Targetmol
    + Info

    FSLLRY-NH2 TFA(245329-02-6 free base)

    <p>FSLLRY-NH2 TFA inhibits PAR2, reverses taxol-induced pain, and reduces itch in mice; blocks ERK and collagen in fibroblasts.</p>
    Formula:C41H61F3N10O10
    Purezza:99.32%
    Colore e forma:Solid
    Peso molecolare:910.99

    Ref: TM-TP1904L