Cellule staminali e Derivati

Gli inibitori delle cellule staminali sono composti che bersagliano specificamente le vie di segnalazione e le proteine coinvolte nel mantenimento, nella differenziazione e nella proliferazione delle cellule staminali. Questi inibitori sono cruciali per comprendere la biologia delle cellule staminali e per sviluppare strategie per manipolare le cellule staminali a fini terapeutici, come la medicina rigenerativa e il trattamento del cancro. Controllando il destino delle cellule staminali, questi inibitori possono aiutare a guidare la differenziazione delle cellule staminali in tipi cellulari specifici o a prevenire una crescita cellulare indesiderata. Presso CymitQuimica, offriamo una selezione di inibitori delle cellule staminali di alta qualità per supportare la tua ricerca in biologia delle cellule staminali, biologia dello sviluppo e medicina rigenerativa.

Sottocategorie di "Cellule staminali e Derivati"

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Trovati 695 prodotti di "Cellule staminali e Derivati"

Purezza (%)

100

prodotti per pagina.

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TTP 22
CAS:
- 329907-28-0
TTP 22: ATP-competitive CK2 inhibitor; IC50/Ki: 0.1 μM/40 nM; >250x selective over JNK3, ROCK1, MET.
Formula:C₁₆H₁₄N₂O₂S₂
Purezza:97.08% - 97.78%
Colore e forma:Solid
Peso molecolare:330.42
Ref: TM-T1828
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SH-4-54
CAS:
- 1456632-40-8
SH-4-54 is a most potent, small molecule, nonphosphorylated STAT3 inhibitor.
Formula:C₂₉H₂₇F₅N₂O₅S
Purezza:98% - 99.12%
Colore e forma:Solid
Peso molecolare:610.59
Ref: TM-T6669
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TDZD-8
CAS:
- 327036-89-5
TDZD-8 (NP 01139) is an inhibitor of GSK-3β, with an IC50 of 2 μM; minimal inhibitory effect observed on CDK1, casein kinase II, PKA and PKC.
Formula:C₁₀H₁₀N₂O₂S
Purezza:97.13% - 99.61%
Colore e forma:White Solid
Peso molecolare:222.26
Ref: TM-T6187
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JI130
CAS:
- 2234271-86-2
JI130 hinders Hes1 transcription repression; notably shrinks pancreatic tumor volume in mice.
Formula:C₂₃H₂₄N₂O₃
Purezza:99.61%
Colore e forma:Solid
Peso molecolare:376.45
Ref: TM-T9588
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GS87
CAS:
- 919936-70-2
GS87 is a highly specific inhibitor of GSK3 (glycogen synthase kinase 3) that induces extensive differentiation of AML cells.
Formula:C₁₆H₁₁N₅O₂S
Purezza:98.86%
Colore e forma:Solid
Peso molecolare:337.36
Ref: TM-T8605
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Tegatrabetan
CAS:
- 1227637-23-1
Tegatrabetan (BC2059) is a small molecule inhibitor of the Wnt/beta-catenin pathway with potential antineoplastic activity.
Formula:C₂₈H₃₆N₄O₆S₂
Purezza:98.01% - 99.18%
Colore e forma:Solid
Peso molecolare:588.74
Ref: TM-T5642
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Baricitinib
CAS:
- 1187594-09-7
Baricitinib (INCB028050) is an orally JAK1 and JAK2 inhibitor. Baricitinib has anti-inflammatory and anti-tumor activity. Cost-effective and quality-assured.
Formula:C₁₆H₁₇N₇O₂S
Purezza:99% - >99.99%
Colore e forma:Solid
Peso molecolare:371.42
Ref: TM-T2485
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Hydroxyfasudil
CAS:
- 105628-72-6
Hydroxyfasudil (Hydroxy-Fasudil) is a ROCK inhibitor(IC50s of 0.73 and 0.72 μM for ROCK1 and ROCK2, respectively).
Formula:C₁₄H₁₇N₃O₃S
Purezza:98.13%
Colore e forma:Solid
Peso molecolare:307.37
Ref: TM-T4276L
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Porcn-IN-1
CAS:
- 2036044-77-4
Porcn-IN-1 (Porcupine-IN-1) is an effective porcupine inhibitor (IC50: 0.5±0.2 nM).
Formula:C₂₅H₁₉FN₄O
Purezza:99.15%
Colore e forma:Solid
Peso molecolare:410.44
Ref: TM-T4438
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Thiazovivin
CAS:
- 1226056-71-8
Thiazovivin, a ROCK inhibitor (IC50: 0.5 μM), increases the survival rate of hESC.
Formula:C₁₅H₁₃N₅OS
Purezza:98.00%
Colore e forma:Solid
Peso molecolare:311.36
Ref: TM-T2155
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GDC-0214
CAS:
- 1831144-46-7
GDC-0214 is an inhaled small-molecule JAK1 inhibitor and reduces fractional exhaled nitric oxide (Feno).
Formula:C₂₈H₂₈ClF₂N₉O₃
Purezza:99.75%
Colore e forma:Solid
Peso molecolare:612.03
Ref: TM-T9826
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IWP-O1
CAS:
- 2074607-48-8
IWP-O1 is a highly potent Porcupine (Porcn) inhibitor (EC50: 80 pM), effectively suppresses the phosphorylation of Dvl2/3 and LRP6 in HeLa cells.
Formula:C₂₆H₂₀N₆O
Purezza:99.12%
Colore e forma:Solid
Peso molecolare:432.48
Ref: TM-T5342
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2,6-Dichloro-N-(2-(cyclopropanecarboxamido)pyridin-4-yl)benzamide
CAS:
- 1258292-64-6
2,6-Dichloro-N-(2-(cyclopropanecarboxamido)pyridin-4-yl)benzamide (GDC046), a potent lead analog, has good kinase selectivity and physicochemical properties.
Formula:C₁₆H₁₃Cl₂N₃O₂
Purezza:98.77%
Colore e forma:Solid
Peso molecolare:350.2
Ref: TM-T22338
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(E/Z)-GO289
CAS:
- 694522-87-7
(E/Z)-GO289, which strongly lengthened circadian period, is a potent and selective inhibitor of CK2.
Formula:C₁₇H₁₅BrN₄O₂S
Purezza:98.1%
Colore e forma:Solid
Peso molecolare:419.3
Ref: TM-T9356
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BIO-013077-01
CAS:
- 746667-48-1
BIO-013077-01 is a potent TGFbeta family type I receptors antagonist.
Formula:C₁₇H₁₃N₅
Purezza:99.87%
Colore e forma:Solid
Peso molecolare:287.32
Ref: TM-T8330
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AS-252424
CAS:
- 900515-16-4
AS-252424 is a potent and selective inhibitor of PI3Kγ with IC50 of 33 nM; >10 fold selectivity for PI3Kγ versus PI3Kα.
Formula:C₁₄H₈FNO₄S
Purezza:99.06% - 99.09%
Colore e forma:Solid
Peso molecolare:305.28
Ref: TM-T6208
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Filgotinib
CAS:
- 1206161-97-8
Filgotinib (GLPG0634) is a selective JAK1 inhibitor. The IC50 values against JAK1, JAK2, JAK3, and TYK2 are 10 nM, 28 nM, 810 nM, and 116 nM, respectively.
Formula:C₂₁H₂₃N₅O₃S
Purezza:98.03% - ≥95%
Colore e forma:Solid
Peso molecolare:425.5
Ref: TM-T1929
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Upadacitinib
CAS:
- 1310726-60-3
Upadacitinib (ABT-494), a selective JAK1 inhibitor, is researched for autoimmune diseases; IC50: 43 nM.
Formula:C₁₇H₁₉F₃N₆O
Purezza:98.96% - 99.94%
Colore e forma:Solid
Peso molecolare:380.37
Ref: TM-T7503
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KenPaullone
CAS:
- 142273-20-9
KenPaullone (9-Bromopaullone), a potent CDK1, CDK2 and CDK5 inhibitor, as new enhancer for iTreg cell differentiation.
Formula:C₁₆H₁₁BrN₂O
Purezza:97.14% - 98.99%
Colore e forma:Tan Solid
Peso molecolare:327.18
Ref: TM-T2247
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Crenigacestat
CAS:
- 1421438-81-4
Crenigacestat (LY3039478) is an orally bioavailable Notch inhibitor with an IC50 of ~1 nM in most of the tumor cell lines tested.
Formula:C₂₂H₂₃F₃N₄O₄
Purezza:97.27% - 98.99%
Colore e forma:Solid
Peso molecolare:464.44
Ref: TM-T3633