Cellule staminali e Derivati
Gli inibitori delle cellule staminali sono composti che bersagliano specificamente le vie di segnalazione e le proteine coinvolte nel mantenimento, nella differenziazione e nella proliferazione delle cellule staminali. Questi inibitori sono cruciali per comprendere la biologia delle cellule staminali e per sviluppare strategie per manipolare le cellule staminali a fini terapeutici, come la medicina rigenerativa e il trattamento del cancro. Controllando il destino delle cellule staminali, questi inibitori possono aiutare a guidare la differenziazione delle cellule staminali in tipi cellulari specifici o a prevenire una crescita cellulare indesiderata. Presso CymitQuimica, offriamo una selezione di inibitori delle cellule staminali di alta qualità per supportare la tua ricerca in biologia delle cellule staminali, biologia dello sviluppo e medicina rigenerativa.
Sottocategorie di "Cellule staminali e Derivati"
- Gamma-secretasi(59 prodotti)
- Proteina Hedgehog/Smoothened(44 prodotti)
- Via di segnalazione Hippo(6 prodotti)
- JAK(245 prodotti)
- Proteina Porcupine(9 prodotti)
- ROCK(70 prodotti)
- STAT(98 prodotti)
- Cellule staminali(486 prodotti)
- TGF-beta/Smad(58 prodotti)
- Wnt/beta-catenina(66 prodotti)
Mostrare 2 più sottocategorie
Trovati 695 prodotti di "Cellule staminali e Derivati"
Ordinare per
Purezza (%)
0
100
|
0
|
50
|
90
|
95
|
100
Afuresertib hydrochloride
CAS:<p>Afuresertib hydrochloride is an inhibitor of Akt kinase (Kis of 0.08/2/2.6 nM for Akt1/Akt2/Akt3 respectively)</p>Formula:C18H18Cl3FN4OSPurezza:99.96%Colore e forma:SolidPeso molecolare:463.8Lats-IN-1
CAS:<p>Lats-IN-1 is a potent and ATP-competitive Lats1 and Lats2 kinases inhibitor. It promotes Yap-dependent proliferation in postmitotic mammalian tissues.</p>Formula:C18H14N4OSPurezza:97.54% - 99.79%Colore e forma:SolidPeso molecolare:334.39Ritlecitinib tosylate
CAS:<p>Ritlecitinib (PF-06651600) is a potent, selective JAK3 inhibitor with proven in vivo efficacy, low clearance, and has undergone clinical trials.</p>Formula:C22H27N5O4SColore e forma:SolidPeso molecolare:457.549AR-A014418
CAS:<p>AR-A014418 (GSK 3β inhibitor VIII) is an ATP-competitive, and selective GSK3β inhibitor.</p>Formula:C12H12N4O4SPurezza:>99.99% - ≥95%Colore e forma:SolidPeso molecolare:308.31BP-1-102
CAS:<p>BP-1-102 is an orally active, effective and specific STAT3 inhibitor.</p>Formula:C29H27F5N2O6SPurezza:99.25% - 99.44%Colore e forma:SolidPeso molecolare:626.59GLPG0634 analog
CAS:<p>GLPG0634 analog (GLPG0634 analogue) is a specific JAK1 inhibitor with IC50 of 10/28/810/116 nM for JAK1/2/3 and TYK2, respectively.</p>Formula:C23H18N6O2Purezza:99.52% - >99.99%Colore e forma:SolidPeso molecolare:410.43XL019
CAS:<p>XL019 is a potent and selective JAK2 inhibitor with IC50 of 2.2 nM, 100 fold selectivity over JAK1.</p>Formula:C25H28N6O2Purezza:99.19%Colore e forma:SolidPeso molecolare:444.53Momelotinib HCl
CAS:<p>Momelotinib HCl is a JAK1/2 inhibitor, reducing anemia in myelofibrosis (MF) patients.</p>Formula:C23H24Cl2N6O2Colore e forma:SolidPeso molecolare:487.38iCRT 14
CAS:<p>iCRT 14 is a novel potent inhibitor of β-catenin-responsive transcription (CRT)(IC50= 40.3 nM in assays of Wnt pathway activity).</p>Formula:C21H17N3O2SPurezza:99.8% - 99.97%Colore e forma:SolidPeso molecolare:375.44Atractylenolide I
CAS:<p>Atractylenolide-I reduces inflammation, improves sepsis, liver, and kidney function, and enhances EOC cell sensitivity to paclitaxel.</p>Formula:C15H18O2Purezza:97.55% - 99.92%Colore e forma:SolidPeso molecolare:230.3(E/Z)-GSK-3β inhibitor 1
CAS:<p>(E/Z)-GSK-3β inhibitor 1 is a glycogen synthase kinase 3β (GSK-3β) inhibitor and demonstrates high antidiabetic efficacy.</p>Formula:C14H10N2OPurezza:98.60%Colore e forma:SolidPeso molecolare:222.24CMD178 TFA
<p>CMD178 (TFA) is a lead peptide that consistently reduces the expression of Foxp3 and STAT5 induced by IL-2/s IL-2Rα signaling.</p>Formula:C48H60F3N9O9Purezza:>99.99%Colore e forma:SolidPeso molecolare:964.05URMC-099
CAS:<p>URMC-099: oral, brain-accessible MLK/LRRK2 inhibitor; IC50 – MLK1/2/3/DLK: 19/42/14/150 nM, LRRK2: 11 nM.</p>Formula:C27H27N5Purezza:99.32% - 99.98%Colore e forma:SolidPeso molecolare:421.54Crenigacestat
CAS:<p>Crenigacestat (LY3039478) is an orally bioavailable Notch inhibitor with an IC50 of ~1 nM in most of the tumor cell lines tested.</p>Formula:C22H23F3N4O4Purezza:97.27% - 98.99%Colore e forma:SolidPeso molecolare:464.44WHI-P154
CAS:<p>WHI-P154 (Jak3 inhibitor ii) is a potent JAK3 inhibitor.</p>Formula:C16H14BrN3O3Purezza:98% - 99.67%Colore e forma:SolidPeso molecolare:376.2SKL2001
CAS:<p>SKL2001, an agonist of the Wnt/β-catenin pathway, can disrupt the Axin/β-catenin interaction.</p>Formula:C14H14N4O3Purezza:97.46% - 99.5%Colore e forma:SolidPeso molecolare:286.29XMU-MP-1
CAS:<p>XMU-MP-1 is a reversible and selective MST1/2 kinase inhibitor, IC50 values for MST1 and MST2 are 71.1 nM and 38.1 nM, respectively. High-Quality, Low-Cost!</p>Formula:C17H16N6O3S2Purezza:99.68% - 99.79%Colore e forma:SolidPeso molecolare:416.48NVP-BSK805 trihydrochloride
CAS:<p>NVP-BSK805 trihydrochloride inhibits JAK2 (0.48 nM IC50); also affects JAK1, JAK3, TYK2.</p>Formula:C27H31Cl3F2N6OColore e forma:SolidPeso molecolare:599.93Pacritinib hydrochloride
CAS:<p>Pacritinib HCl: strong JAK2/Wild-type & JAK2V617F inhibitor (IC50: 23/19 nM), used in AML & MF research.</p>Formula:C28H32N4O3·xClHColore e forma:SolidBMS-911543
CAS:<p>BMS-911543 is a potent and selective inhibitor of JAK2 with IC50 of 1.1 nM, ~350-, 75- and 65-fold selective to JAK1, JAK3 and TYK2, respectively. Phase 1/2.</p>Formula:C23H28N8OPurezza:97.69% - 99.98%Colore e forma:SolidPeso molecolare:432.52Fosciclopirox
CAS:<p>Fosciclopirox (CPX-POM), the phosphoryloxymethyl ester of CPX (Ciclopirox Prodrug, CPX-POM), selectively delivers the active metabolite, CPX, to the entire</p>Formula:C13H20NO6PPurezza:99.83%Colore e forma:SolidPeso molecolare:317.27SAR407899 hydrochloride
CAS:<p>SAR407899 hydrochloride is a selective, potent and ATP-competitive ROCK inhibitor, with an IC50 of 135 nM for ROCK-2, and Kis of 36 nM and 41 nM for human and</p>Formula:C14H17ClN2O2Purezza:99.15%Colore e forma:SolidPeso molecolare:280.75Cardiogenol C
CAS:<p>Cardiogenol C is a cardiomyogenesis inducer in embryonic stem cells.</p>Formula:C13H16N4O2Purezza:98.46%Colore e forma:SolidPeso molecolare:260.29AZD1080
CAS:<p>AZD1080 is a selective, orally active, brain permeable GSK3 inhibitor.</p>Formula:C19H18N4O2Purezza:97.72% - 99.75%Colore e forma:SolidPeso molecolare:334.37IMR-1A
CAS:<p>IMR-1A is the metabolite of IMR-1 which is a novel class of Notch inhibitors targeting the transcriptional activation with IC50 of 6 μMol/L.</p>Formula:C13H11NO5S2Purezza:97.1% - 99.76%Colore e forma:SolidPeso molecolare:325.36RKI1313
CAS:<p>RKI1313 (RKI-1313) was a selective inhibitor for ROCK-dependent signaling, cytoskeletal changes, anchorage-independent colony formation, migration, and invasion</p>Formula:C17H16N4O2SPurezza:99.53% - ≥95%Colore e forma:SolidPeso molecolare:340.4FH535
CAS:<p>FH535, a Wnt/β-catenin signaling and PPAR inhibitor, exhibits anti-tumor activities.</p>Formula:C13H10Cl2N2O4SPurezza:98.25% - 99.5%Colore e forma:SolidPeso molecolare:361.2I3MT-3
CAS:<p>I3MT-3 (HMPSNE) is a selective inhibitor of 3MST, targeting active site cysteine residues and permeating cell membranes.</p>Formula:C17H14N2O2SPurezza:99.76%Colore e forma:SolidPeso molecolare:310.37Teplinovivint
CAS:<p>Teplinovivint is a potent inhibitor of the Wnt/β-catenin signaling pathway, demonstrating anti-inflammatory properties with potential utility in tendinopathy</p>Formula:C25H26N6O2Purezza:97.21%Colore e forma:SolidPeso molecolare:442.512,6-Dichloro-N-(2-(cyclopropanecarboxamido)pyridin-4-yl)benzamide
CAS:<p>2,6-Dichloro-N-(2-(cyclopropanecarboxamido)pyridin-4-yl)benzamide (GDC046), a potent lead analog, has good kinase selectivity and physicochemical properties.</p>Formula:C16H13Cl2N3O2Purezza:98.77%Colore e forma:SolidPeso molecolare:350.2ML116
CAS:<p>ML116 is a potent and selective STAT3 inhibitor.</p>Formula:C18H19N3SPurezza:99.49%Colore e forma:SolidPeso molecolare:309.43TTP 22
CAS:<p>TTP 22: ATP-competitive CK2 inhibitor; IC50/Ki: 0.1 μM/40 nM; >250x selective over JNK3, ROCK1, MET.</p>Formula:C16H14N2O2S2Purezza:97.08% - 97.78%Colore e forma:SolidPeso molecolare:330.42Cucurbitacin I
CAS:<p>Cucurbitacin I (JSI-124), a natural compound, is a selective inhibitor of JAK2/STAT3 with anti-cancer activity.</p>Formula:C30H42O7Purezza:96.69% - 99.8%Colore e forma:SolidPeso molecolare:514.65β-catenin-IN-2
CAS:<p>β-catenin-IN-2 is a potent inhibitor of β-catenin that can be used in colorectal cancer research.</p>Formula:C15H14FN3Purezza:99.93%Colore e forma:SolidPeso molecolare:255.29SH-4-54
CAS:<p>SH-4-54 is a most potent, small molecule, nonphosphorylated STAT3 inhibitor.</p>Formula:C29H27F5N2O5SPurezza:98% - 99.12%Colore e forma:SolidPeso molecolare:610.59TDZD-8
CAS:<p>TDZD-8 (NP 01139) is an inhibitor of GSK-3β, with an IC50 of 2 μM; minimal inhibitory effect observed on CDK1, casein kinase II, PKA and PKC.</p>Formula:C10H10N2O2SPurezza:97.13% - 99.61%Colore e forma:White SolidPeso molecolare:222.26JI130
CAS:<p>JI130 hinders Hes1 transcription repression; notably shrinks pancreatic tumor volume in mice.</p>Formula:C23H24N2O3Purezza:99.61%Colore e forma:SolidPeso molecolare:376.45GS87
CAS:<p>GS87 is a highly specific inhibitor of GSK3 (glycogen synthase kinase 3) that induces extensive differentiation of AML cells.</p>Formula:C16H11N5O2SPurezza:98.86%Colore e forma:SolidPeso molecolare:337.36WAY 316606
CAS:<p>WAY 316606 is an inhibitor of the secreted protein sFRP-1, an endogenous antagonist of the secreted glycoprotein Wnt.</p>Formula:C18H19F3N2O4S2Purezza:99.65%Colore e forma:SolidPeso molecolare:448.48ZM39923 hydrochloride
CAS:<p>ZM39923 hydrochloride (JAK3 Inhibitor IV) is an JAK1/3 inhibitor, almost no activity to JAK2 and modestly potent to EGFR; also is sensitive to transglutaminase.</p>Formula:C23H25NO·HClPurezza:98.05%Colore e forma:SolidPeso molecolare:367.91Tegatrabetan
CAS:<p>Tegatrabetan (BC2059) is a small molecule inhibitor of the Wnt/beta-catenin pathway with potential antineoplastic activity.</p>Formula:C28H36N4O6S2Purezza:98.01% - 99.18%Colore e forma:SolidPeso molecolare:588.74Baricitinib
CAS:<p>Baricitinib (INCB028050) is an orally JAK1 and JAK2 inhibitor. Baricitinib has anti-inflammatory and anti-tumor activity. Cost-effective and quality-assured.</p>Formula:C16H17N7O2SPurezza:99% - >99.99%Colore e forma:SolidPeso molecolare:371.42Hydroxyfasudil
CAS:<p>Hydroxyfasudil (Hydroxy-Fasudil) is a ROCK inhibitor(IC50s of 0.73 and 0.72 μM for ROCK1 and ROCK2, respectively).</p>Formula:C14H17N3O3SPurezza:98.13%Colore e forma:SolidPeso molecolare:307.37GDC-0214
CAS:<p>GDC-0214 is an inhaled small-molecule JAK1 inhibitor and reduces fractional exhaled nitric oxide (Feno).</p>Formula:C28H28ClF2N9O3Purezza:99.75%Colore e forma:SolidPeso molecolare:612.03IWP-O1
CAS:<p>IWP-O1 is a highly potent Porcupine (Porcn) inhibitor (EC50: 80 pM), effectively suppresses the phosphorylation of Dvl2/3 and LRP6 in HeLa cells.</p>Formula:C26H20N6OPurezza:99.12%Colore e forma:SolidPeso molecolare:432.48LY3200882
CAS:<p>LY3200882 is a highly selective inhibitor of TGF-β receptor type 1 (TGFβRI).</p>Formula:C24H29N5O3Purezza:99.46% - 99.63%Colore e forma:SolidPeso molecolare:435.52YO-01027
CAS:<p>YO-01027 (DBZ) is a potent γ-secretase inhibitor.</p>Formula:C26H23F2N3O3Purezza:97.21% - 99.58%Colore e forma:SolidPeso molecolare:463.48AS1517499
CAS:<p>AS1517499 is a blood-brain barrier permeable inhibitor of STAT6 phosphorylation (IC50= 21 nM). High-Quality, Low-Cost!</p>Formula:C20H20ClN5O2Purezza:98.27% - 98.7%Colore e forma:SolidPeso molecolare:397.86Porcn-IN-1
CAS:<p>Porcn-IN-1 (Porcupine-IN-1) is an effective porcupine inhibitor (IC50: 0.5±0.2 nM).</p>Formula:C25H19FN4OPurezza:99.15%Colore e forma:SolidPeso molecolare:410.44GNF4877
CAS:<p>GNF4877 inhibits DYRK1A/GSK3β (IC50: 6/16 nM), blocks NFATc export, and boosts β-cell growth.</p>Formula:C25H27FN6O4Purezza:98.68% - 99.40%Colore e forma:SolidPeso molecolare:494.52
