Wnt/beta-catenina
Gli inibitori della via Wnt/beta-catenina sono composti che inibiscono la via di segnalazione Wnt/beta-catenina, cruciale per la regolazione dello sviluppo embrionale, della proliferazione cellulare e del mantenimento delle cellule staminali. La disfunzione di questa via è legata a vari tipi di cancro e malattie degenerative. Gli inibitori della segnalazione Wnt/beta-catenina sono preziosi per la ricerca volta a comprendere il ruolo di questa via nelle malattie e a sviluppare terapie mirate. Presso CymitQuimica, offriamo inibitori di Wnt/beta-catenina per supportare la tua ricerca in biologia delle cellule staminali, biologia dello sviluppo e ricerca sul cancro.
Trovati 62 prodotti di "Wnt/beta-catenina"
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PRI-724
CAS:PRI-724 is a second-generation, selective small molecule inhibitor of the β-catenin/CBP interaction.Cost-effective and quality-assured.
Formula:C33H35N6O7PPurezza:98.25% - 99.11%Colore e forma:SoildPeso molecolare:658.64ZW4864 free base
CAS:ZW4864 (free base) is an orally active and selective β catenin/B-Cell lymphoma 9 protein protein interaction ( β catenin/BCL9 PPI ) inhibitor.
Formula:C33H42N6O3Purezza:99.81%Colore e forma:SolidPeso molecolare:570.72β-catenin/CBP-IN-1
CAS:β-catenin/CBP-IN-1 is a potent and selective inhibitor of CBP/β-cateninFormula:C33H35N6O7PPurezza:98%Colore e forma:SolidPeso molecolare:658.64Wnt pathway activator 2
CAS:Wnt pathway activator 2 is a potent Wnt activator with an IC50 of 13 nM.Formula:C17H15NO4Purezza:99.41%Colore e forma:SolidPeso molecolare:297.31Ref: TM-T13345
1mg52,00€5mg100,00€10mg160,00€25mg329,00€50mg533,00€100mg770,00€200mg1.035,00€1mL*10mM (DMSO)111,00€GB1874
CAS:GB1874 is an inhibitor of the Wnt pathway targeting β-catenin-TCF4 protein-protein interaction (PPI), affecting proliferation in Wnt-dependent CRC cells.Formula:C24H27N3O2SColore e forma:SolidPeso molecolare:421.56FzM1
CAS:FzM1, a negative allosteric modulator (NAM) of the Frizzled receptor FZD4, diminishes WNT5A-dependent WNT responsive element (WRE) activity (log EC50inh=−6.2)Formula:C21H16N2O2SPurezza:99.37% - 99.89%Colore e forma:SolidPeso molecolare:360.43Ref: TM-T24076
1mg42,00€5mg64,00€10mg99,00€25mg188,00€50mg328,00€100mg528,00€500mg1.130,00€1mL*10mM (DMSO)62,00€FzM1.8
CAS:FzM1.8: allosteric FZD4 agonist, pEC50=6.4; boosts TCF/LEF, activates WNT/β-catenin with no WNT needed.Formula:C18H14N2O4Purezza:99.89%Colore e forma:SolidPeso molecolare:322.31Ref: TM-T15363
2mg38,00€5mg55,00€10mg87,00€25mg165,00€50mg264,00€100mg411,00€200mg593,00€1mL*10mM (DMSO)89,00€Wnt/β-catenin agonist 4
CAS:Wnt/β-catenin agonist 4 is an agonist of Wnt that activates Wnt/β-catenin signaling and directs signaling.Formula:C16H15FN4O2Purezza:99.96%Colore e forma:SolidPeso molecolare:314.31Ref: TM-T60803
1mg34,00€5mg66,00€10mg98,00€25mg172,00€50mg295,00€100mg485,00€200mg682,00€1mL*10mM (DMSO)77,00€JW 67
CAS:JW 67 is an inhibitor of canonical Wnt pathway signaling.Formula:C21H18N2O6Purezza:99.02%Colore e forma:SolidPeso molecolare:394.38Ref: TM-T22884
1mg43,00€2mg56,00€5mg93,00€10mg130,00€25mg259,00€50mg416,00€100mg613,00€1mL*10mM (DMSO)92,00€β-Catenin modulator-8
CAS:β-Catenin modulator-8 (Compound Ⅸa) is a specific β-catenin modulator for use in cancer research.Formula:C17H20N2O2SPurezza:99.97%Colore e forma:SolidPeso molecolare:316.42Ref: TM-T205083
1mg201,00€5mg497,00€10mg701,00€25mg1.094,00€50mg1.508,00€100mg1.931,00€200mg2.637,00€Carboxylesterase-IN-3
CAS:Carboxylesterase-IN-3 is a potent inhibitor of Carboxylesterase Notum (IC50 ≤ 10 nM).Carboxylesterase-IN-3 has the potential to study cancer diseases.
Formula:C11H6Cl2N4OSPurezza:97.49% - 98.47%Colore e forma:SolidPeso molecolare:313.16NRX-103095
CAS:NRX-103095 increases β-catenin binding to SCFβ-TrCP E3 ligase; EC50 is 163 nM for pSer33/Ser37 affinity boost.Formula:C22H16Cl2F3N3O3SPurezza:99.85% - 99.95%Colore e forma:SolidPeso molecolare:530.35Ref: TM-T63730
1mg150,00€5mg364,00€10mg588,00€25mg1.169,00€50mg1.882,00€100mg2.822,00€1mL*10mM (DMSO)426,00€
