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Cellule staminali

Cellule staminali

Gli inibitori delle cellule staminali sono composti che mirano specificamente alle cellule staminali e alle loro vie di segnalazione, influenzando la loro capacità di autorinnovarsi e differenziarsi. Questi inibitori sono cruciali nella ricerca focalizzata sul controllo del comportamento delle cellule staminali, sulla comprensione dei processi di sviluppo e sullo sviluppo di terapie per malattie come il cancro, dove si ritiene che le cellule staminali svolgano un ruolo chiave. Presso CymitQuimica, offriamo una varietà di inibitori delle cellule staminali per supportare la tua ricerca in medicina rigenerativa, biologia dello sviluppo e oncologia.

Trovati 463 prodotti di "Cellule staminali"

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  • 1-Azakenpaullone
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    1-Azakenpaullone

    CAS:
    1-Azakenpaullone (azakenpaullone) is a potent and selective GSK-3β inhibitor with IC50 of 18 nM, >100-fold selectivity over CDK1/cyclin B and CDK5/p25.
    Formula:C15H10BrN3O
    Purezza:99.73%
    Colore e forma:Tan Solid
    Peso molecolare:328.16

    Ref: TM-T6358

  • SD-1029
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    SD-1029

    CAS:
    SD-1029 is a JAK2 inhibitor and a novel Stat3 activation inhibitor that inhibits Stat3 phosphorylation and JAK-STAT signaling.
    Formula:C25H32Br2Cl2N2O3
    Colore e forma:Solid
    Peso molecolare:639.25

    Ref: TM-T24774

  • CJJ300
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    CJJ300

    CAS:
    <p>CJJ300 is a TGF-β inhibitor disrupting TGF-β-TβR complex formation, with an IC50 of 5.3 μM, and halts cell migration.</p>
    Formula:C30H33N3
    Purezza:99.80%
    Colore e forma:Solid
    Peso molecolare:435.6

    Ref: TM-T62483

  • GSK3-IN-2
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    GSK3-IN-2

    CAS:
    <p>GSK3-IN-2 is a potent GSK3 inhibitor for the treatment of diabetes and neurodegenerative diseases.</p>
    Formula:C17H19N3OS
    Purezza:98.8%
    Colore e forma:Solid
    Peso molecolare:313.42

    Ref: TM-T73270

  • CAY10746
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    CAY10746

    CAS:
    CAY10746 selectively inhibits ROCK I/II with IC50s: 0.014/0.003 μM, useful for diabetic retinopathy research.
    Formula:C26H23N3O5
    Purezza:99.71%
    Colore e forma:Solid
    Peso molecolare:457.48

    Ref: TM-T36196

  • Aloisine B
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    Aloisine B

    CAS:
    <p>Aloisine B (AloisineB) inhibited cyclin-dependent kinase and glycogen synthase kinase with IC50 values of 0.85 µM and 0.75 µM, respectively.</p>
    Formula:C15H14ClN3
    Purezza:95.15%
    Colore e forma:Solid
    Peso molecolare:271.74

    Ref: TM-T69188

  • JAK3i
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    JAK3i

    CAS:
    <p>JAK3i selectively inhibits JAK3 kinase, targeting the second, vital wave of STAT5 phosphorylation for T cell growth.</p>
    Formula:C18H15FN4O3
    Purezza:98.61% - 99.81%
    Colore e forma:Solid
    Peso molecolare:354.34

    Ref: TM-T27650

  • BRD0209
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    BRD0209

    CAS:
    <p>BRD0209 is a highly selective and potent GSK3 inhibitor.</p>
    Formula:C22H25N3O
    Purezza:99.92%
    Colore e forma:Solid
    Peso molecolare:347.45

    Ref: TM-T26894

  • VT103
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    VT103

    CAS:
    VT103, an oral TEAD1 palmitoylation inhibitor, shows promise against various cancers by disrupting YAP/TAZ-TEAD interactions.
    Formula:C18H17F3N4O2S
    Purezza:99.58%
    Colore e forma:Solid
    Peso molecolare:410.41

    Ref: TM-T62077

  • PIMPC
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    PIMPC

    CAS:
    PIMPC, a compound endowed with antioxidant and metal-chelating properties, acts as a novel inhibitor of glycogen synthase kinase 3 (GSK-3), and exhibits
    Formula:C21H19N5O
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:357.41

    Ref: TM-T79693

  • Logo CymitQuimica
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    AF-2112

    <p>AF-2112, a TEAD inhibitor derived from Flufenamic acid, significantly diminishes the expression of CTGF, Cyr61, Axl, and NF2.</p>
    Formula:C21H18FNO3
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:351.37

    Ref: TM-T79428

  • SR-1277
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    SR-1277

    CAS:
    SR-1277 is a potent, highly selective and ATP-competitive CK1δ/ε inhibitor, regulating Wee1 activity at the G2/M cell-cycle interface, and antiproliferative.
    Formula:C21H19N9O3S
    Colore e forma:Solid
    Peso molecolare:477.5

    Ref: TM-T38927

  • JA310
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    JA310

    CAS:
    JA310 is a highly selective inhibitor of the MST3 kinase, demonstrating significant cellular potency with an EC50 value of 106 nM [1].
    Formula:C17H19N7O
    Colore e forma:Solid
    Peso molecolare:337.38

    Ref: TM-T86752

  • JAK1-IN-4
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    JAK1-IN-4

    CAS:
    JAK1-IN-4 selectively blocks JAK1 (IC50 = 85 nM) over JAK2/JAK3 and halts STAT3 phosphorylation in NCI-H 1975 cells (IC50 = 227 nM).
    Formula:C26H32FN9O2
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:521.59

    Ref: TM-T15606

  • JAK-IN-11
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    JAK-IN-11

    CAS:
    JAK-IN-11 (R-348) is a potent and selective inhibitor of JAK, has the potential for the skin disorders treatment.
    Formula:C23H22FN5O4S
    Purezza:99.75%
    Colore e forma:Solid
    Peso molecolare:483.52

    Ref: TM-T12549

  • TEAD-IN-2
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    TEAD-IN-2

    CAS:
    <p>TEAD-IN-2 is a potent and bifunctional TEAD inhibitor to induce TEAD protein degradation via the ubiquitination pathway, with anticancer potential.</p>
    Formula:C16H18BrF3N2O
    Colore e forma:Solid
    Peso molecolare:391.23

    Ref: TM-T61776

  • GSK-3β inhibitor 12
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    GSK-3β inhibitor 12

    CAS:
    GSK-3β inhibitor 12 is a selective GSK-3β inhibitor.GSK-3β inhibitor 12 inhibits 49.11% of 25 μM GSK-3β activity and 37.11% of 50 μM GSK-3β activity.GSK-3β
    Formula:C14H13N3OS
    Purezza:98.58%
    Colore e forma:Solid
    Peso molecolare:271.34

    Ref: TM-T60472

  • JAK3/BTK-IN-2
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    JAK3/BTK-IN-2

    CAS:
    <p>JAK3/ BTk-in-2 is a potent JAK3/BTK inhibitor.</p>
    Formula:C25H32N8O2
    Purezza:99.64% - 99.87%
    Colore e forma:Solid
    Peso molecolare:476.57

    Ref: TM-T9813

  • Chromenone 1
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    Chromenone 1

    CAS:
    Chromenone 1 is a potent potentiator of osteogenic bone morphogenetic protein (BMP).
    Formula:C18H10F3N3O2
    Purezza:99.83% - 99.93%
    Colore e forma:Solid
    Peso molecolare:357.29

    Ref: TM-T61301

  • γ-secretase modulator 1
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    γ-secretase modulator 1

    CAS:
    gamma-secretase modulator 1 is a modulator of γ secretase and can be used in studies about the treatment of Alzheimer's disease.
    Formula:C24H24N4OS
    Purezza:99.75% - 99.96%
    Colore e forma:Solid
    Peso molecolare:416.54

    Ref: TM-T11358