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Cellule staminali

Cellule staminali

Gli inibitori delle cellule staminali sono composti che mirano specificamente alle cellule staminali e alle loro vie di segnalazione, influenzando la loro capacità di autorinnovarsi e differenziarsi. Questi inibitori sono cruciali nella ricerca focalizzata sul controllo del comportamento delle cellule staminali, sulla comprensione dei processi di sviluppo e sullo sviluppo di terapie per malattie come il cancro, dove si ritiene che le cellule staminali svolgano un ruolo chiave. Presso CymitQuimica, offriamo una varietà di inibitori delle cellule staminali per supportare la tua ricerca in medicina rigenerativa, biologia dello sviluppo e oncologia.

Trovati 463 prodotti di "Cellule staminali"

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  • Casein kinase 1δ-IN-5
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    Casein kinase 1δ-IN-5

    CAS:
    Casein kinase 1δ-IN-5 is a potent and selective CK-1δ inhibitor, exhibiting an IC50 of 47 nM, and demonstrates neuroprotective and anti-inflammatory effects in
    Formula:C16H11F3N2OS
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:336.33

    Ref: TM-T79154

  • TCS 21311
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    TCS 21311

    CAS:
    <p>TCS 21311 (NIBR3049) selectively inhibits JAK3 (IC50: 8 nM) and PKCα/θ &amp; GSK3β; &gt;100x selective over JAK1, JAK2, TYK2.</p>
    Formula:C27H25F3N4O4
    Purezza:99.39% - ≥98%
    Colore e forma:Solid
    Peso molecolare:526.51

    Ref: TM-T17019

  • MRK-560
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    MRK-560

    CAS:
    MRK-560 is an effective and brain-penetrant inhibitor of γ-secretase.
    Formula:C19H17ClF5NO4S2
    Purezza:98.87%
    Colore e forma:Solid
    Peso molecolare:517.92

    Ref: TM-T16133

  • TP0427736
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    TP0427736

    CAS:
    TP0427736: ALK5 inhibitor, IC50=2.72 nM, 300x > ALK3 selectivity; counters TGF-β in human cells, extends anagen in mice.
    Formula:C14H10N4S2
    Purezza:97.26%
    Colore e forma:Solid
    Peso molecolare:298.39

    Ref: TM-T24897

  • STAT3-IN-B9
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    STAT3-IN-B9

    CAS:
    STAT3-IN-B9 (B9) is an inhibitor of abnormal STAT3 activation and inhibits the proliferation of tumor cells including MDA-MB-468, MDA-MB-231, and DU145.
    Formula:C20H13NO5S
    Purezza:98.19%
    Colore e forma:Solid
    Peso molecolare:379.39

    Ref: TM-T28865

  • ML115
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    ML115

    CAS:
    ML115 is a potent and selective activator of transcription 3 (STAT3), with abn EC50 of 2.0 nM, and is inactive against the related STAT1 and NFκB anti-targets.
    Formula:C15H15ClN2O4
    Purezza:99.97%
    Colore e forma:Solid
    Peso molecolare:322.74

    Ref: TM-T35544

  • LX7101
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    LX7101

    CAS:
    LX7101 is an effective inhibitor of LIMK and ROCK2 (IC50: 24, 1.6, and 10 nM for LIMK1, LIMK2, and ROCK2, respectively). It also inhibits PKA (IC50 <1 nM).
    Formula:C23H29N7O3
    Purezza:99.08%
    Colore e forma:Solid
    Peso molecolare:451.52

    Ref: TM-T15798

  • BMS-983970
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    BMS-983970

    CAS:
    BMS-983970 is an oral inhibitor of pan-Notch, and for the treatment of multiplecancers.
    Formula:C26H26F4N4O3
    Colore e forma:Solid
    Peso molecolare:518.5

    Ref: TM-T14683

  • Stafib-2
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    Stafib-2

    CAS:
    <p>Stafib-2 is a potent and selective inhibitor of the transcription factor STAT5b.Stafib-2 inhibits STAT5b and STAT5a with IC50 values of 82 nM and 1.7 μM,</p>
    Formula:C28H26N2O12P2
    Purezza:98.48%
    Colore e forma:Solid
    Peso molecolare:644.46

    Ref: TM-T9646

  • JW 67
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    JW 67

    CAS:
    <p>JW 67 is an inhibitor of canonical Wnt pathway signaling.</p>
    Formula:C21H18N2O6
    Purezza:99.02%
    Colore e forma:Solid
    Peso molecolare:394.38

    Ref: TM-T22884

  • ROCK2-IN-2
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    ROCK2-IN-2

    CAS:
    ROCK2-IN-2 is a selective inhibitor of ROCK2 (IC50 of <1 μM).
    Formula:C18H12N6OS
    Purezza:99.65%
    Colore e forma:Solid
    Peso molecolare:360.39

    Ref: TM-T12747

  • TM2 TEAD inhibitor
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    TM2 TEAD inhibitor

    CAS:
    TM2 TEAD inhibitor, a robust and reversible inhibitor of the TEA domain transcription factor, presents dual inhibitory concentrations (IC50) of 38 nM for TEAD4
    Formula:C26H33N3O3
    Purezza:99.91%
    Colore e forma:Solid
    Peso molecolare:435.57

    Ref: TM-T83951

  • JAK-IN-31
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    JAK-IN-31

    CAS:
    JAK-IN-31 (Example 75), a JAK inhibitor, demonstrates IC50 values of ≤0.01 µM for JAK1, ≤0.01 µM for JAK2, 0.01-0.1 µM for JAK3, and ≤0.01 µM for Tyk2,
    Formula:C21H19N7O2S2
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:465.55

    Ref: TM-T79882

  • 3,7-DMF
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    3,7-DMF

    CAS:
    3,7-Dimethylfumarate (3,7-DMF) serves as an oral inhibitor of transforming growth factor-beta 1 (TGF-β1)-mediated hepatic stellate cell (HSC) activation.
    Formula:C17H14O4
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:282.29

    Ref: TM-T79603

  • DT-6
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    DT-6

    CAS:
    <p>DT-6, a potent TGF-β1 inhibitor, impedes M2 macrophage-induced epithelial-to-mesenchymal transition and the invasive migration of cancer cells, thereby showing</p>
    Formula:C89H130N20O29S2
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:2008.23

    Ref: TM-T79789

  • QL-1200186
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    QL-1200186

    CAS:
    QL-1200186 is an orally active, selective TYK2 inhibitor that, upon dose-dependent oral administration, suppresses interferon-γ (IFNγ) production following
    Formula:C26H27N7O3
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:485.54

    Ref: TM-T81331

  • JAK kinase-IN-1
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    JAK kinase-IN-1

    CAS:
    <p>JAK kinase-IN-1 (Example 1) functions as a potent inhibitor targeting the JAK family, which includes TYK2, JAK1, JAK2, and JAK3, with IC50 values of 4.2 nM, 32</p>
    Formula:C17H19F2N7OS
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:407.44

    Ref: TM-T79807

  • JAK2-IN-4
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    JAK2-IN-4

    CAS:
    JAK2-IN-4 is a selective JAK2/JAK3 inhibitor, with IC50 values of 0.7 nM and 23.2 nM for JAK2 and JAK3, respectively.
    Formula:C23H27N5O4S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:469.56

    Ref: TM-T11708

  • ROCK-IN-8
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    ROCK-IN-8

    CAS:
    ROCK-IN-8 (Example 4), a ROCK inhibitor, exhibits anti-inflammatory properties and is suitable for respiratory and gastro-intestinal disease research,
    Formula:C30H25FN4O4S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:556.61

    Ref: TM-T79809

  • ROCK-IN-1
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    ROCK-IN-1

    CAS:
    <p>ROCK-IN-1 is a potent ROCK inhibitor that inhibits ROCK2-mediated signaling with an IC50 value of 1.2 nM.ROCK-IN-1 can be used in the study of neurological</p>
    Formula:C20H18FN3O
    Purezza:>99.99%
    Colore e forma:Solid
    Peso molecolare:335.37

    Ref: TM-T13419