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Recettore del fattore di crescita dei fibroblasti (FGFR)

Recettore del fattore di crescita dei fibroblasti (FGFR)

Gli inibitori dei recettori del fattore di crescita dei fibroblasti (FGFR) sono terapie mirate che bloccano l'attività dei FGFR, coinvolti nella proliferazione cellulare, differenziazione e angiogenesi. La segnalazione FGFR contribuisce alla formazione di nuovi vasi sanguigni nei tumori, promuovendo la loro crescita e sopravvivenza. Inibire i FGFR può quindi ridurre l'angiogenesi e la progressione del tumore. Presso CymitQuimica, offriamo una gamma di inibitori FGFR di alta qualità per supportare la tua ricerca in oncologia, biologia dello sviluppo e angiogenesi.

Trovati 169 prodotti di "Recettore del fattore di crescita dei fibroblasti (FGFR)"

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  • NSC 12
    Targetmol
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    NSC 12

    CAS:
    <p>NSC 12 is an orally active pan-FGF trap that binds FGF2 and interferes with its interaction with FGFR1 with potential FGF-dependent antitumor activity.</p>
    Formula:C24H34F6O3
    Purezza:99.51%
    Colore e forma:Solid
    Peso molecolare:484.52

    Ref: TM-T36292

  • Nintedanib
    TCI
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    Nintedanib

    CAS:
    Formula:C31H33N5O4
    Purezza:>95.0%(T)(HPLC)
    Colore e forma:White to Yellow to Yellow green powder to crystal
    Peso molecolare:539.64

    Ref: 3B-N1313

    1g
    266,00€
    200mg
    78,00€
  • SM27
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    SM27

    CAS:
    <p>SM27 is a fibroblast growth factor 2 (FGF2) inhibitor with anti-angiogenic activity and can be used to study tumours.</p>
    Formula:C21H16N2O9S2
    Purezza:98.83%
    Colore e forma:Solid
    Peso molecolare:504.49

    Ref: TM-T24804

  • (Z)-Orantinib
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    (Z)-Orantinib

    CAS:
    <p>(Z)-Orantinib, oral ATP-competitive blocker for Flk-1/KDR, PDGFRβ, FGFR1 (IC50: 2.1, 0.008, 1.2 μM), is a strong antiangiogenic, antitumor drug.</p>
    Formula:C18H18N2O3
    Colore e forma:Solid
    Peso molecolare:310.35

    Ref: TM-T9684

  • PD-161570
    TCI
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    PD-161570

    CAS:
    Formula:C26H35Cl2N7O
    Purezza:>98.0%(HPLC)
    Colore e forma:White to Light yellow powder to crystal
    Peso molecolare:532.51

    Ref: 3B-P2531

    5mg
    99,00€
    25mg
    335,00€
  • FIIN-3
    Targetmol
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    FIIN-3

    CAS:
    <p>FIIN-3 is an irreversible inhibitor of FGFR.</p>
    Formula:C34H36Cl2N8O4
    Purezza:97.63% - 98.92%
    Colore e forma:Solid
    Peso molecolare:691.61

    Ref: TM-T3466

  • Masitinib
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    Masitinib

    CAS:
    <p>Masitinib (AB1010) is a tyrosine-kinase inhibitor used in the treatment of mast cell tumors in animals, specifically dogs.</p>
    Formula:C28H30N6OS
    Purezza:97.56% - >99.99%
    Colore e forma:Solid
    Peso molecolare:498.64

    Ref: TM-T2609

  • S49076 HCl
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    S49076 HCl

    CAS:
    <p>S49076 HCl (S-49076 Hydrochloride) is an effective inhibitor of MET, AXL/MER, and FGFR1/2/3.</p>
    Formula:C22H18ClN3O5
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:439.85

    Ref: TM-T3512

  • Dovitinib lactate
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    Dovitinib lactate

    CAS:
    <p>Dovitinib lactate (TKI-258 lactate)(TKI258) lactate is a potent inhibitor of fibroblast growth factor receptor 3 (FGFR3) (IC50 :5 nM).</p>
    Formula:C24H27FN6O4
    Purezza:99.54% - 99.77%
    Colore e forma:Solid
    Peso molecolare:482.51

    Ref: TM-T7104

  • R1530
    Targetmol
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    R1530

    CAS:
    <p>R1530 is a multikinase inhibitor with antineoplastic and antiangiogenesis activities.</p>
    Formula:C18H14ClFN4O
    Purezza:98.422%
    Colore e forma:Solid
    Peso molecolare:356.78

    Ref: TM-TQ0317

  • PRN1371
    Targetmol
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    PRN1371

    CAS:
    <p>PRN1371 is a specific and potent FGFR1-4 and CSF1R inhibitor (IC50s: 0.6/1.3/4.1/19.3/8.1 nM for FGFR1/2/3/4 and CSF1R).</p>
    Formula:C26H30Cl2N6O4
    Purezza:98.65%
    Colore e forma:Solid
    Peso molecolare:561.46

    Ref: TM-TQ0015

  • KHS 101
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    KHS 101

    CAS:
    <p>KHS101 is a novel inhibitor of transforming acidic coiled-coil protein 3 (TACC3). It is a selective inducer of neuronal differentiation.</p>
    Formula:C18H21N5S
    Purezza:99.63%
    Colore e forma:Solid
    Peso molecolare:339.46

    Ref: TM-T4968

  • SU4984
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    SU4984

    CAS:
    <p>SU4984 is a cell-permeable, ATP-competitive and reversible inhibitor of the fibroblast growth factor receptor 1 (FGFR1).</p>
    Formula:C20H19N3O2
    Purezza:97.20%
    Colore e forma:Solid
    Peso molecolare:333.38

    Ref: TM-T9030

  • PF 477736
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    PF 477736

    CAS:
    <p>PF 477736 (PF-736,PF-00477736) is a specifc, effective and ATP-competitive Chk1 inhibitor (Ki: 0.49 nM ) and also inhibits FGFR3, Aurora-A, VEGFR2, Flt3, Fms (</p>
    Formula:C22H25N7O2
    Purezza:97.58% - 99.94%
    Colore e forma:Solid
    Peso molecolare:419.48

    Ref: TM-T6028

  • Masitinib mesylate
    Targetmol
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    Masitinib mesylate

    CAS:
    <p>Masitinib mesylate (AB-1010 mesylate) is a selective and orally bioavailable c-Kit inhibitor (IC50 of 200 nM,540/800 nM,510 nM for human recombinant c-Kit;</p>
    Formula:C29H34N6O4S2
    Purezza:97.67% - 98.44%
    Colore e forma:Solid
    Peso molecolare:594.75

    Ref: TM-T8544

  • Ferulic acid sodium
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    Ferulic acid sodium

    CAS:
    <p>Ferulic acid sodium (Sodium ferulic) is an agent used in the treatment of cardiovascular and cerebrovascular diseases and to prevent thrombosis.</p>
    Formula:C10H9NaO4
    Purezza:99.58%
    Colore e forma:White Crystalline Powder
    Peso molecolare:216.16

    Ref: TM-T2S0007

  • Alofanib
    Targetmol
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    Alofanib

    CAS:
    <p>Alofanib (RPT835) selectively inhibits FGFR2 in KATO III cells with IC50 &lt;10 nM; doesn’t affect FGFR1/3 or FGF2-FGFR2 binding.</p>
    Formula:C19H15N3O6S
    Purezza:99.53% - 99.81%
    Colore e forma:Solid
    Peso molecolare:413.4

    Ref: TM-T5122

  • Futibatinib
    Targetmol
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    Futibatinib

    CAS:
    Futibatinib (TAS-120) is an orally active, potent,and irreversible FGFR inhibitor of FGFR1, FGFR2, FGFR3, and FGFR4.Cost-effective and quality-assured.
    Formula:C22H22N6O3
    Purezza:97.66% - 99.44%
    Colore e forma:Solid
    Peso molecolare:418.45

    Ref: TM-T5044

  • GW786034B
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    GW786034B

    CAS:
    <p>Pazopanib HCl (Votrient) inhibits VEGFR1-3, PDGFR, FGFR, c-Kit, c-Fms with IC50 range 10-146 nM in cell-free assays.</p>
    Formula:C21H23N7O2S·HCl
    Purezza:99.87%
    Colore e forma:Solid
    Peso molecolare:473.98

    Ref: TM-T6930

  • Dovitinib lactate hydrate
    Targetmol
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    Dovitinib lactate hydrate

    CAS:
    <p>Dovitinib lactate hydrate (TKI258) is the Lactate of Dovitinib, which is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit).</p>
    Formula:C24H27FN6O4
    Purezza:99.82%
    Colore e forma:Solid
    Peso molecolare:482.51

    Ref: TM-T6479