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Recettore del fattore di crescita dei fibroblasti (FGFR)

Recettore del fattore di crescita dei fibroblasti (FGFR)

Gli inibitori dei recettori del fattore di crescita dei fibroblasti (FGFR) sono terapie mirate che bloccano l'attività dei FGFR, coinvolti nella proliferazione cellulare, differenziazione e angiogenesi. La segnalazione FGFR contribuisce alla formazione di nuovi vasi sanguigni nei tumori, promuovendo la loro crescita e sopravvivenza. Inibire i FGFR può quindi ridurre l'angiogenesi e la progressione del tumore. Presso CymitQuimica, offriamo una gamma di inibitori FGFR di alta qualità per supportare la tua ricerca in oncologia, biologia dello sviluppo e angiogenesi.

Trovati 169 prodotti di "Recettore del fattore di crescita dei fibroblasti (FGFR)"

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  • FGFR2-IN-3 hydrochloride
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    FGFR2-IN-3 hydrochloride

    CAS:
    <p>FGFR2-IN-3 hydrochloride is a selective, orally active FGFR2 inhibitor.</p>
    Formula:C28H25ClFN7O2
    Colore e forma:Solid
    Peso molecolare:546.0

    Ref: TM-T63850

  • FIIN-3
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    FIIN-3

    CAS:
    <p>FIIN-3 is an irreversible inhibitor of FGFR.</p>
    Formula:C34H36Cl2N8O4
    Purezza:97.63% - 98.92%
    Colore e forma:Solid
    Peso molecolare:691.61

    Ref: TM-T3466

  • EOC317
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    EOC317

    CAS:
    <p>EOC317 (ACTB-1003) is an oral kinase inhibitor (IC50: 6/2/4 nM, for FGFR1/VEGFR2/Tie-2).</p>
    Formula:C27H26F5N7O3
    Purezza:98.00% - 99.26%
    Colore e forma:Solid
    Peso molecolare:591.53

    Ref: TM-T4318

  • Derazantinib
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    Derazantinib

    CAS:
    <p>Derazantinib (ARQ-087) is a potent, ATP-competitive, orally active tyrosine kinase inhibitor.Cost-effective and quality-assured.</p>
    Formula:C29H29FN4O
    Purezza:99.71%
    Colore e forma:Solid
    Peso molecolare:468.57

    Ref: TM-TQ0228

  • Zoligratinib
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    Zoligratinib

    CAS:
    Zoligratinib (CH5183284) is a selective and orally available FGFR inhibitor, which is for FGFR1, FGFR2, FGFR3, and FGFR4, respectively.
    Formula:C20H16N6O
    Purezza:95.28% - 99.51%
    Colore e forma:Solid
    Peso molecolare:356.38

    Ref: TM-T6024

  • KHS 101
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    KHS 101

    CAS:
    <p>KHS101 is a novel inhibitor of transforming acidic coiled-coil protein 3 (TACC3). It is a selective inducer of neuronal differentiation.</p>
    Formula:C18H21N5S
    Purezza:99.63%
    Colore e forma:Solid
    Peso molecolare:339.46

    Ref: TM-T4968

  • PD173074
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    PD173074

    CAS:
    <p>PD173074 inhibits FGFR1 (IC50: 25 nM) and VEGFR2 (100-200 nM); ~1000x more selective for FGFR1 over PDGFR/c-Src.</p>
    Formula:C28H41N7O3
    Purezza:98.15% - 98.21%
    Colore e forma:Yellow Solid
    Peso molecolare:523.67

    Ref: TM-T2642

  • PD-161570
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    PD-161570

    CAS:
    <p>PD-161570 is a potent and ATP-competitive human FGF-1 receptor inhibitor with an IC50 of 39.9 nM and a Ki of 42 nM.</p>
    Formula:C26H35Cl2N7O
    Purezza:99.92%
    Colore e forma:Solid
    Peso molecolare:532.51

    Ref: TM-T23127

  • Erdafitinib
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    Erdafitinib

    CAS:
    <p>Erdafitinib (JNJ-42756493) is a quinoxaline derivative compound, acts on FGFR1/2/3/4.</p>
    Formula:C25H30N6O2
    Purezza:97.00% - 99.07%
    Colore e forma:Solid
    Peso molecolare:446.54

    Ref: TM-T3726

  • S49076
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    S49076

    CAS:
    <p>S49076 is a novel, potent inhibitor of MET, AXL/MER, and FGFR1/2/3, blocking cellular phosphorylation of MET, AXL, and FGFRs.</p>
    Formula:C22H22N4O4S
    Purezza:95.35% - 97.4%
    Colore e forma:Solid
    Peso molecolare:438.5

    Ref: TM-T3274

  • ASP5878
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    ASP5878

    CAS:
    <p>ASP5878 potently inhibited the tyrosine kinase activities of recombinant FGFR1, 2, 3, and 4 with IC50 values of 0.47, 0.60, 0.74, and 3.5 nmol/L.</p>
    Formula:C18H19F2N5O4
    Purezza:99.8% - 99.89%
    Colore e forma:Solid
    Peso molecolare:407.37

    Ref: TM-T5473

  • Heparan Sulfate
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    Heparan Sulfate

    CAS:
    <p>Heparan sulfate is a natural product, a linear polysaccharide. Heparan sulfate occurs as a proteoglycan (HSPG). Cost effective and quality assured.</p>
    Formula:C12H19NO20S3(monomer)
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:593.47(monomer)

    Ref: TM-T19355

  • Nintedanib esylate
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    Nintedanib esylate

    CAS:
    <p>Nintedanib esylate (BIBF 1120 esylate) is a potent triple angiokinase inhibitor for VEGFR1/2/3, FGFR1/2/3 and PDGFRα/β</p>
    Formula:C31H33N5O4·C2H6O3S
    Purezza:99.43% - 99.96%
    Colore e forma:Solid
    Peso molecolare:649.76

    Ref: TM-T5001

  • Gandotinib
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    Gandotinib

    CAS:
    <p>LY2784544(Gandotinib (LY2784544)) is a potent JAK2 inhibitor (IC50: 3 nM), effective in JAK2V617F(Ki: 0.245 nM).</p>
    Formula:C23H25ClFN7O
    Purezza:99.33% - 99.86%
    Colore e forma:Solid
    Peso molecolare:469.94

    Ref: TM-T2638

  • Fisogatinib
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    Fisogatinib

    CAS:
    <p>Fisogatinib (BLU-554) is a highly potent, selective, and orally active FGFR4 inhibitor.Cost-effective and quality-assured.</p>
    Formula:C24H24Cl2N4O4
    Purezza:99.27% - ≥95%
    Colore e forma:Solid
    Peso molecolare:503.38

    Ref: TM-T3456

  • Orantinib
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    Orantinib

    CAS:
    <p>Orantinib (NSC 702827) , a excellent effective against PDGFR autophosphorylation with Ki of 8 nM, also highly inhibits Flk-1 and FGFR1 trans-phosphorylation.</p>
    Formula:C18H18N2O3
    Purezza:98.92% - 99.52%
    Colore e forma:Solid
    Peso molecolare:310.35

    Ref: TM-T6184

  • FIIN-2
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    FIIN-2

    CAS:
    <p>FIIN-2, an irreversible, pan-FGFR inhibitor, inhibits FGFR1/2/3/4 with IC50 of 3.09 nM, 4.3 nM, 27 nM and 45.3 nM, respectively.</p>
    Formula:C35H38N8O4
    Purezza:97.82% - 99.65%
    Colore e forma:Crystalline Solid
    Peso molecolare:634.73

    Ref: TM-T6836

  • LY2874455
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    LY2874455

    CAS:
    <p>LY2874455 has been used in trials studying the treatment of Advanced Cancer.</p>
    Formula:C21H19Cl2N5O2
    Purezza:97.22% - 99.46%
    Colore e forma:Solid
    Peso molecolare:444.31

    Ref: TM-T2361

  • AZD4547
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    AZD4547

    CAS:
    <p>AZD4547 is an FGFR family inhibitor, and is able to act on FGFR1, FGFR2, FGFR3 and FGFR4. IC50:165 nM).Cost-effective and quality-assured.</p>
    Formula:C26H33N5O3
    Purezza:99.37% - 99.88%
    Colore e forma:Solid
    Peso molecolare:463.57

    Ref: TM-T1948

  • R1530
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    R1530

    CAS:
    <p>R1530 is a multikinase inhibitor with antineoplastic and antiangiogenesis activities.</p>
    Formula:C18H14ClFN4O
    Purezza:98.422%
    Colore e forma:Solid
    Peso molecolare:356.78

    Ref: TM-TQ0317