Recettore di Ephrin
Gli inibitori del recettore Ephrin sono diretti ai recettori Eph, una famiglia di tirosina chinasi recettoriali che interagiscono con ligandi ephrin legati alla membrana. La segnalazione ephrin è cruciale per il posizionamento cellulare, la modellazione dei tessuti e l'angiogenesi. La disregolazione di questa via è implicata nel cancro, nelle malattie neurodegenerative e nei disturbi dello sviluppo. Presso CymitQuimica, offriamo inibitori dei recettori Ephrin per supportare la tua ricerca in biologia dello sviluppo, oncologia e neurobiologia.
Trovati 24 prodotti di "Recettore di Ephrin"
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AWL-II-38.3
CAS:AWL-II-38.3 is a highly potent EphA3 inhibitor with potent kinase inhibitory activity against EphA3.Cost-effective and quality-assured.Formula:C23H18F3N5O3Purezza:99.03% - 99.57%Colore e forma:SolidPeso molecolare:469.42EphA2 agonist 1
CAS:Compound 7bg is a potent, selective EphA2 agonist targeting overexpressed glioblastoma cells.Formula:C50H58N12O12Colore e forma:SolidPeso molecolare:1019.07Nuzefatide
CAS:Nuzefatide is a peptide that binds to liver protein receptors.Formula:C105H162N32O27S3Colore e forma:SolidPeso molecolare:2400.80ALW-II-49-7
CAS:<p>ALW-II-49-7 is a selective and potent inhibitor of EphB2 kinase with an EC50 value of 40 nM in cell.</p>Formula:C21H17F3N4O2Purezza:99.72%Colore e forma:SoildPeso molecolare:414.38SA-PA
SA-PA, a self-assembled intracellular PROTAC leveraging azide-alkyne click chemistry, selectively degrades VEGFR-2, PDGFR-β, and EphB4 proteins within U87 cellsFormula:C40H32ClF3N10O8Purezza:98%Colore e forma:SolidPeso molecolare:873.19PKMYT1-IN-8
<p>PKMYT1-IN-8 (Compound 137) is an inhibitor of PKMYT1, with an IC50 value of 9 nM. It also inhibits EPHB3, EPHA1, KIT, EPHB1, EPHA2, EPHA3, and EPHB2, exhibiting IC50 values of 1.79, 3.17, 4.29, 6.32, 6.83, 8.10, and 10.9 μM, respectively. Additionally, PKMYT1-IN-8 suppresses the proliferation of cancer cells OVCAR3 with a GI50 of 2.02 μM.</p>Formula:C17H16F3N5O2Colore e forma:SolidPeso molecolare:379.336AZ12672857
CAS:<p>AZ12672857 is an inhibitor of EphB4 with IC50 of 1.3 nM.</p>Formula:C26H30N8O2Purezza:98.99%Colore e forma:SolidPeso molecolare:486.57UniPR1449
<p>UniPR1449 is an EphA2 receptor antagonist with a KD of 3.8±2.4 μM, which is significant in cancer pathophysiology [1].</p>Purezza:98%Colore e forma:Odour SolidKYL peptide
CAS:EphA4 inhibitor, Kd 0.8 μM, blocks EphA4-EphrinA5; avoids AβO damage, preserves spines & LTP; long half-life (8-12h), neuroprotective.Formula:C74H108N14O17Purezza:98%Colore e forma:SolidPeso molecolare:1465.75Ehp-inhibitor-2
CAS:<p>Ehp-inhibitor-2 is an Eph family tyrosine kinase inhibitor targeting Eph receptors.</p>Formula:C17H13N5OPurezza:97.88%Colore e forma:SolidPeso molecolare:303.32NVP-BHG712 isomer
CAS:NVP-BHG712 isomer shows conserved non-bonded binding to EPHA2 and EPHB4.Formula:C26H20F3N7OPurezza:99.14%Colore e forma:SolidPeso molecolare:503.48JI-101
CAS:JI-101 (CGI-1842) is an oral multi-kinase inhibitor that targets VEGFR-2, PDGFR-β, and EphB4.Formula:C22H20BrN5O2Purezza:99.41% - 99.97%Colore e forma:SolidPeso molecolare:466.33NVP-BHG712
CAS:NVP-BHG712 is a specific EphB4 inhibitor with ED50 of 25 nM that discriminates between VEGFR and EphB4 inhibition; also shows activity against c-Raf, c-Src andFormula:C26H20F3N7OPurezza:97.32% - 98.63%Colore e forma:SolidPeso molecolare:503.48Eph inhibitor 2
CAS:Eph inhibitor 2 is an Eph family tyrosine kinase inhibitor targeting Eph receptors.Formula:C18H15N5OPurezza:99.01%Colore e forma:SolidPeso molecolare:317.34Tesevatinib
CAS:Tesevatinib (XL-647) is an oral, multi-targeted tyrosine kinase inhibitor.Cost-effective and quality-assured.Formula:C24H25Cl2FN4O2Purezza:97.89% - 98.66%Colore e forma:SolidPeso molecolare:491.39KYL acetate(676657-00-4 free base)
EphA4 inhibitor, Kd: 0.8 μM, IC50: 6.34 μM. Protects synapses and spines, maintains LTP. Long half-life: 8-12h. Neuroprotective.Formula:C76H112N14O19Purezza:99.75%Colore e forma:SolidPeso molecolare:1525.78ALW-II-41-27
CAS:ALW-II-41-27 (Eph receptor tyrosine kinase inhibitor), an Eph receptor tyrosine kinase inhibitor, is used for cancer therapy.Formula:C32H32F3N5O2SPurezza:97.01% - 99.52%Colore e forma:SolidPeso molecolare:607.69123C4
CAS:123C4 is a potent, selective and competitive agonist of the receptor tyrosine kinase EPHA4 (Ki=0.65 μM)[1].Formula:C43H47ClN8O6Purezza:98.94%Colore e forma:SolidPeso molecolare:807.34UniPR129
CAS:UniPR129 is a competitive Eph-ephrin antagonist agent that acts by blocking in vitro angiogenesis at low micromolar concentrations.Formula:C36H52N2O4Purezza:98%Colore e forma:SolidPeso molecolare:576.81EphA2 agonist 2
CAS:EphA2 agonist 2 (Lead compound) is a selective agonist targeting the EphA2 receptor, exhibiting antitumor properties and the ability to cross the blood-brainFormula:C40H56N10O6Colore e forma:SolidPeso molecolare:772.94
