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Recettore di Ephrin

Recettore di Ephrin

Gli inibitori del recettore Ephrin sono diretti ai recettori Eph, una famiglia di tirosina chinasi recettoriali che interagiscono con ligandi ephrin legati alla membrana. La segnalazione ephrin è cruciale per il posizionamento cellulare, la modellazione dei tessuti e l'angiogenesi. La disregolazione di questa via è implicata nel cancro, nelle malattie neurodegenerative e nei disturbi dello sviluppo. Presso CymitQuimica, offriamo inibitori dei recettori Ephrin per supportare la tua ricerca in biologia dello sviluppo, oncologia e neurobiologia.

Trovati 25 prodotti di "Recettore di Ephrin"

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  • EphA2 agonist 1

    CAS:
    Compound 7bg is a potent, selective EphA2 agonist targeting overexpressed glioblastoma cells.
    Formula:C50H58N12O12
    Colore e forma:Solid
    Peso molecolare:1019.07

    Ref: TM-T74611

    5mg
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    50mg
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  • Nuzefatide

    CAS:
    Nuzefatide is a peptide that binds to liver protein receptors.
    Formula:C105H162N32O27S3
    Colore e forma:Solid
    Peso molecolare:2400.80

    Ref: TM-TP3269

    10mg
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    50mg
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  • ALW-II-49-7

    CAS:
    <p>ALW-II-49-7 is a selective and potent inhibitor of EphB2 kinase with an EC50 value of 40 nM in cell.</p>
    Formula:C21H17F3N4O2
    Purezza:99.72%
    Colore e forma:Soild
    Peso molecolare:414.38

    Ref: TM-T67736

    1mg
    71,00€
    5mg
    166,00€
    10mg
    243,00€
    25mg
    439,00€
    50mg
    647,00€
    100mg
    920,00€
    500mg
    1.853,00€
  • SA-PA


    SA-PA, a self-assembled intracellular PROTAC leveraging azide-alkyne click chemistry, selectively degrades VEGFR-2, PDGFR-β, and EphB4 proteins within U87 cells
    Formula:C40H32ClF3N10O8
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:873.19

    Ref: TM-T79530

    5mg
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    50mg
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  • PKMYT1-IN-8


    <p>PKMYT1-IN-8 (Compound 137) is an inhibitor of PKMYT1, with an IC50 value of 9 nM. It also inhibits EPHB3, EPHA1, KIT, EPHB1, EPHA2, EPHA3, and EPHB2, exhibiting IC50 values of 1.79, 3.17, 4.29, 6.32, 6.83, 8.10, and 10.9 μM, respectively. Additionally, PKMYT1-IN-8 suppresses the proliferation of cancer cells OVCAR3 with a GI50 of 2.02 μM.</p>
    Formula:C17H16F3N5O2
    Colore e forma:Solid
    Peso molecolare:379.336

    Ref: TM-T204125

    10mg
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    50mg
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  • AZ12672857

    CAS:
    <p>AZ12672857 is an inhibitor of EphB4 with IC50 of 1.3 nM.</p>
    Formula:C26H30N8O2
    Purezza:98.99%
    Colore e forma:Solid
    Peso molecolare:486.57

    Ref: TM-T9650

    1mg
    70,00€
    2mg
    93,00€
    5mg
    155,00€
    10mg
    259,00€
    25mg
    424,00€
    50mg
    662,00€
    100mg
    894,00€
  • UniPR1449


    UniPR1449 is an EphA2 receptor antagonist with a KD of 3.8±2.4 μM, which is significant in cancer pathophysiology [1].
    Purezza:98%
    Colore e forma:Odour Solid

    Ref: TM-T80896

    5mg
    Prezzo su richiesta
    50mg
    Prezzo su richiesta
  • KYL peptide

    CAS:
    EphA4 inhibitor, Kd 0.8 μM, blocks EphA4-EphrinA5; avoids AβO damage, preserves spines & LTP; long half-life (8-12h), neuroprotective.
    Formula:C74H108N14O17
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:1465.75

    Ref: TM-TP1895

    1mg
    775,00€
  • AWL-II-38.3

    CAS:
    AWL-II-38.3 is a highly potent EphA3 inhibitor with potent kinase inhibitory activity against EphA3.Cost-effective and quality-assured.
    Formula:C23H18F3N5O3
    Purezza:99.03% - 99.57%
    Colore e forma:Solid
    Peso molecolare:469.42

    Ref: TM-T38511

    1mg
    81,00€
    5mg
    170,00€
    10mg
    264,00€
    25mg
    543,00€
    50mg
    780,00€
    100mg
    1.074,00€
    500mg
    2.167,00€
    1mL*10mM (DMSO)
    177,00€
  • 123C4

    CAS:
    123C4 is a potent, selective and competitive agonist of the receptor tyrosine kinase EPHA4 (Ki=0.65 μM)[1].
    Formula:C43H47ClN8O6
    Purezza:98.94%
    Colore e forma:Solid
    Peso molecolare:807.34

    Ref: TM-TP1561

    1mg
    144,00€
    5mg
    311,00€
    10mg
    512,00€
    25mg
    815,00€
    50mg
    1.093,00€
    100mg
    1.473,00€
    1mL*10mM (DMSO)
    507,00€
  • Ehp-inhibitor-2

    CAS:
    Ehp-inhibitor-2 is an Eph family tyrosine kinase inhibitor targeting Eph receptors.
    Formula:C17H13N5O
    Purezza:97.88%
    Colore e forma:Solid
    Peso molecolare:303.32

    Ref: TM-T5452

    2mg
    38,00€
    5mg
    58,00€
    10mg
    92,00€
    25mg
    155,00€
    50mg
    221,00€
    100mg
    325,00€
    200mg
    469,00€
    1mL*10mM (DMSO)
    65,00€
  • NVP-BHG712 isomer

    CAS:
    NVP-BHG712 isomer shows conserved non-bonded binding to EPHA2 and EPHB4.
    Formula:C26H20F3N7O
    Purezza:99.14%
    Colore e forma:Solid
    Peso molecolare:503.48

    Ref: TM-T19487

    1mg
    43,00€
    2mg
    56,00€
    5mg
    88,00€
    10mg
    150,00€
    25mg
    259,00€
    50mg
    376,00€
    100mg
    560,00€
    1mL*10mM (DMSO)
    87,00€
  • JI-101

    CAS:
    JI-101 (CGI-1842) is an oral multi-kinase inhibitor that targets VEGFR-2, PDGFR-β, and EphB4.
    Formula:C22H20BrN5O2
    Purezza:99.41% - 99.97%
    Colore e forma:Solid
    Peso molecolare:466.33

    Ref: TM-T3476

    1mg
    37,00€
    5mg
    79,00€
    10mg
    111,00€
    25mg
    187,00€
    50mg
    303,00€
    100mg
    472,00€
    1mL*10mM (DMSO)
    87,00€
  • NVP-BHG712

    CAS:
    NVP-BHG712 is a specific EphB4 inhibitor with ED50 of 25 nM that discriminates between VEGFR and EphB4 inhibition; also shows activity against c-Raf, c-Src and
    Formula:C26H20F3N7O
    Purezza:97.32% - 98.63%
    Colore e forma:Solid
    Peso molecolare:503.48

    Ref: TM-T6348

    1mg
    35,00€
    5mg
    79,00€
    10mg
    111,00€
    25mg
    212,00€
    50mg
    393,00€
    100mg
    587,00€
    200mg
    833,00€
    1mL*10mM (DMSO)
    88,00€
  • Eph inhibitor 2

    CAS:
    Eph inhibitor 2 is an Eph family tyrosine kinase inhibitor targeting Eph receptors.
    Formula:C18H15N5O
    Purezza:99.01%
    Colore e forma:Solid
    Peso molecolare:317.34

    Ref: TM-T5451

    1mg
    95,00€
    2mg
    125,00€
    5mg
    188,00€
    10mg
    284,00€
    25mg
    515,00€
    50mg
    742,00€
    100mg
    1.035,00€
    500mg
    2.080,00€
    1mL*10mM (DMSO)
    187,00€
  • Tesevatinib

    CAS:
    Tesevatinib (XL-647) is an oral, multi-targeted tyrosine kinase inhibitor.Cost-effective and quality-assured.
    Formula:C24H25Cl2FN4O2
    Purezza:97.89% - 98.66%
    Colore e forma:Solid
    Peso molecolare:491.39

    Ref: TM-TQ0166

    1mg
    107,00€
    2mg
    156,00€
    5mg
    236,00€
    10mg
    457,00€
    25mg
    750,00€
    50mg
    1.026,00€
    1mL*10mM (DMSO)
    255,00€
  • KYL acetate(676657-00-4 free base)


    EphA4 inhibitor, Kd: 0.8 μM, IC50: 6.34 μM. Protects synapses and spines, maintains LTP. Long half-life: 8-12h. Neuroprotective.
    Formula:C76H112N14O19
    Purezza:99.75%
    Colore e forma:Solid
    Peso molecolare:1525.78

    Ref: TM-TP1895L1

    1mg
    131,00€
    5mg
    286,00€
    10mg
    430,00€
    25mg
    710,00€
    50mg
    998,00€
    100mg
    1.349,00€
  • Tivozanib

    CAS:
    Tivozanib (KRN951) is an oral VEGFRs 1-3 inhibitor with potential antiangiogenic and cancer-fighting properties.
    Formula:C22H19ClN4O5
    Purezza:98.08% - 99.67%
    Colore e forma:Solid
    Peso molecolare:454.86

    Ref: TM-T2456

    2mg
    38,00€
    5mg
    57,00€
    10mg
    79,00€
    25mg
    135,00€
    50mg
    226,00€
    100mg
    405,00€
    200mg
    597,00€
    1mL*10mM (DMSO)
    63,00€
  • ALW-II-41-27

    CAS:
    ALW-II-41-27 (Eph receptor tyrosine kinase inhibitor), an Eph receptor tyrosine kinase inhibitor, is used for cancer therapy.
    Formula:C32H32F3N5O2S
    Purezza:97.01% - 99.52%
    Colore e forma:Solid
    Peso molecolare:607.69

    Ref: TM-T4344

    1mg
    63,00€
    5mg
    159,00€
    10mg
    236,00€
    25mg
    371,00€
    50mg
    522,00€
    100mg
    713,00€
    200mg
    982,00€
    1mL*10mM (DMSO)
    216,00€
  • UniPR129

    CAS:
    UniPR129 is a competitive Eph-ephrin antagonist agent that acts by blocking in vitro angiogenesis at low micromolar concentrations.
    Formula:C36H52N2O4
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:576.81

    Ref: TM-T26310

    25mg
    870,00€
    50mg
    1.130,00€
    100mg
    1.805,00€
  • EphA2 agonist 2

    CAS:
    EphA2 agonist 2 (Lead compound) is a selective agonist targeting the EphA2 receptor, exhibiting antitumor properties and the ability to cross the blood-brain
    Formula:C40H56N10O6
    Colore e forma:Solid
    Peso molecolare:772.94

    Ref: TM-T72765

    25mg
    1.444,00€
    50mg
    1.882,00€
    100mg
    2.375,00€
  • LDN-211904 oxalate

    CAS:
    LDN-211904 oxalate (LDN211904 oxalate) is a selective and efficient EphB3 inhibitor with antitumor activity, useful in neurodegenerative disease research.
    Formula:C21H21ClN4O5
    Purezza:99.87%
    Colore e forma:Solid
    Peso molecolare:444.87

    Ref: TM-T21762

    1mg
    120,00€
    5mg
    288,00€
    10mg
    432,00€
    25mg
    695,00€
    50mg
    949,00€
    1mL*10mM (DMSO)
    329,00€
  • UniPR505

    CAS:
    <p>UniPR505 is a potent EphA2 antagonist (IC50: 0.95 µM), a novel 3α-carbamoyloxy derivative with antiangiogenic properties.</p>
    Formula:C39H57N3O5
    Purezza:98.23%
    Colore e forma:Solid
    Peso molecolare:647.89

    Ref: TM-T73368

    1mg
    492,00€
    5mg
    1.111,00€
    25mg
    1.825,00€
    50mg
    2.262,00€
    100mg
    2.945,00€
  • UniPR1447

    CAS:
    UniPR1447 is a dual antagonist for both EphA2 and EphB2 receptors, exhibiting an IC50 value of 6.6 μM against EphA2-ephrin-A1 binding [1].
    Formula:C36H50N2O4
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:574.79

    Ref: TM-T80897

    5mg
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    50mg
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  • UniPR500

    CAS:
    UniPR500, a derivative of UniPR129, is a competitive antagonist for the EphA2 receptor, with a Ki of 0.78 μM. It reduces the binding of biotinylated Ephrin-A1 to EphA2 in a dose-dependent manner, exhibiting an IC50 value of 1.1 μM.
    Formula:C36H51N3O4
    Colore e forma:Solid
    Peso molecolare:589.808

    Ref: TM-T204989

    10mg
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    50mg
    Prezzo su richiesta