c-Fms
Gli inibitori di c-Fms prendono di mira il recettore del fattore stimolante delle colonie-1 (c-Fms), una tirosina chinasi coinvolta nella regolazione dei macrofagi e di altre cellule immunitarie. La segnalazione di c-Fms svolge un ruolo nella proliferazione, differenziazione e sopravvivenza di queste cellule. La disregolazione di c-Fms è associata a malattie come il cancro, condizioni infiammatorie e osteoporosi. Presso CymitQuimica, offriamo inibitori di c-Fms per supportare la tua ricerca in immunologia, oncologia e malattie infiammatorie.
Trovati 108 prodotti di "c-Fms"
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PLX647
CAS:<p>PLX647 is a highly selective dual FMS/KIT kinase inhibitor (IC50: 28/16 nM).</p>Formula:C21H17F3N4Purezza:99.38%Colore e forma:SolidPeso molecolare:382.38CSF1R Protein, Human, Recombinant (His & Avi)
<p>M-CSFR/CSF1R/CD115 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag.</p>Colore e forma:Lyophilized PowderPeso molecolare:57.4 kDa (predicted). Due to glycosylation, the protein migrates to 75-105 kDa based on Tris-Bis PAGE result.Anti-CSF1R Antibody (4Y587)
<p>Anti-CSF1R Antibody (4Y587) is a Mouse antibody targeting CSF1R. Anti-CSF1R Antibody (4Y587) can be used in FCM.</p>Colore e forma:Odour LiquidGW786034B
CAS:<p>Pazopanib HCl (Votrient) inhibits VEGFR1-3, PDGFR, FGFR, c-Kit, c-Fms with IC50 range 10-146 nM in cell-free assays.</p>Formula:C21H23N7O2S·HClPurezza:99.87%Colore e forma:SolidPeso molecolare:473.98Seralutinib
CAS:<p>Seralutinib (GB002) is an inhibitor of inhaled PDGFRα and PDGFRβ. It is used in the study for pulmonary arterial hypertension.</p>Formula:C27H27N5O3Purezza:99.09%Colore e forma:SolidPeso molecolare:469.54AZD7507
CAS:<p>AZD7507 is a CSF-1R inhibitor with an IC50 of 32 nM. AZD7507 has antitumor activity.</p>Formula:C23H27FN6O3Purezza:99.55% - 99.78%Colore e forma:SolidPeso molecolare:454.5PRN1371
CAS:<p>PRN1371 is a specific and potent FGFR1-4 and CSF1R inhibitor (IC50s: 0.6/1.3/4.1/19.3/8.1 nM for FGFR1/2/3/4 and CSF1R).</p>Formula:C26H30Cl2N6O4Purezza:98.65%Colore e forma:SolidPeso molecolare:561.46Pexidartinib
CAS:<p>Pexidartinib (PLX-3397) is a capsule formulation containing a small-molecule receptor tyrosine kinase (RTK) inhibitor of KIT, CSF1R and FLT3 with potential</p>Formula:C20H15ClF3N5Purezza:98.34% - 99.45%Colore e forma:SolidPeso molecolare:417.81cFMS Receptor Inhibitor II
CAS:<p>cFMS Receptor Inhibitor II is a CSF1R kinase inhibitor</p>Formula:C23H20N4OPurezza:99.8%Colore e forma:SolidPeso molecolare:368.43PF 477736
CAS:<p>PF 477736 (PF-736,PF-00477736) is a specifc, effective and ATP-competitive Chk1 inhibitor (Ki: 0.49 nM ) and also inhibits FGFR3, Aurora-A, VEGFR2, Flt3, Fms (</p>Formula:C22H25N7O2Purezza:97.58% - 99.94%Colore e forma:SolidPeso molecolare:419.48Ki20227
CAS:<p>Ki-20227 is a specific c-Fms tyrosine kinase(CSF1R) inhibitor (IC50: 2 nM).</p>Formula:C24H24N4O5SPurezza:98.97% - 99.88%Colore e forma:SolidPeso molecolare:480.54Vimseltinib
CAS:<p>Vimseltinib (DCC-3014) is a c-FMS (CSF-IR) and c-Kit dual inhibitor (IC50s: <0.01 μM and 0.1-1 μM).</p>Formula:C23H25N7O2Purezza:99.05% - 99.57%Colore e forma:SolidPeso molecolare:431.49Sotuletinib
CAS:<p>Sotuletinib (BLZ945) is an orally active, effective and specific CSF-1R inhibitor, >1000-fold selective against its closest receptor tyrosine kinase homologs.</p>Formula:C20H22N4O3SPurezza:97.43% - 99.82%Colore e forma:SolidPeso molecolare:398.48AZ304
CAS:<p>AZ304 is an ATP-competitive dual BRAF kinase inhibitor, potently inhibits BRAF (WT), BRAF (V600E), and wild type CRAF (IC50s: 79/38/68 nM).</p>Formula:C27H25N5O2Purezza:99.82%Colore e forma:SolidPeso molecolare:451.52GW2580
CAS:<p>GW2580 (SC-203877) is a specific, oral-bioavailable CSF-1R inhibitor for c-FMS.</p>Formula:C20H22N4O3Purezza:99.48% - >99.99%Colore e forma:SolidPeso molecolare:366.41PLX5622
CAS:<p>PLX5622 is a selective, orally active and blood-brain barrier permeable CSF1R inhibitor. PLX5622 induces elimination of microglia. Cost effective and quality assured.</p>Formula:C21H19F2N5OPurezza:98% - 99.92%Colore e forma:SolidPeso molecolare:395.41Linifanib
CAS:<p>Linifanib (AL-39324) (ABT-869) is a novel, potent ATP-competitive VEGFR/PDGFR inhibitor for KDR (IC50: 4 nM), CSF-1R (IC50: 3 nM), Flt-1/3 (IC50: 3/4 nM) and</p>Formula:C21H18FN5OPurezza:98% - 98.24%Colore e forma:SolidPeso molecolare:375.4Nampt-IN-1
CAS:<p>Nampt-IN-1 (LSN3154567) (LSN3154567) is a potent and selective NAMPT inhibitor. Nampt-IN-1 inhibits purified NAMPT with an IC50 of 3.1 nM.</p>Formula:C20H25N3O5SPurezza:99.28% - 99.4%Colore e forma:SolidPeso molecolare:419.49OSI-930
CAS:<p>OSI-930 is an oral c-Kit/VEGFR-2 inhibitor targeting tumor growth and angiogenesis.</p>Formula:C22H16F3N3O2SPurezza:99.67%Colore e forma:SolidPeso molecolare:443.44Dovitinib
CAS:<p>Dovitinib is an orally active, multi-targeted tyrosine kinase (RTK) inhibitor with anti-tumor effects.Cost-effective and quality-assured.</p>Formula:C21H21FN6OPurezza:99.35% - 99.92%Colore e forma:SolidPeso molecolare:392.43
