c-Fms
Gli inibitori di c-Fms prendono di mira il recettore del fattore stimolante delle colonie-1 (c-Fms), una tirosina chinasi coinvolta nella regolazione dei macrofagi e di altre cellule immunitarie. La segnalazione di c-Fms svolge un ruolo nella proliferazione, differenziazione e sopravvivenza di queste cellule. La disregolazione di c-Fms è associata a malattie come il cancro, condizioni infiammatorie e osteoporosi. Presso CymitQuimica, offriamo inibitori di c-Fms per supportare la tua ricerca in immunologia, oncologia e malattie infiammatorie.
Trovati 108 prodotti di "c-Fms"
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Anumigilimab
CAS:<p>Anumigilimab (CSL-324) is a fully human therapeutic anti-G-CSFR antibody with potential anti-tumor activity for the study of inflammation.</p>Purezza:95.75% (SEC-HPLC) - 98.43% (SEC-HPLC)Colore e forma:LiquidPeso molecolare:143.86 kDaLenzilumab
CAS:<p>Lenzilumab (KB 003) is a humanized GM-CSF neutralizing antibody for the study of COVID-19.</p>Purezza:98.9% (SDS-PAGE); 98.5% (SEC-HPLC) - 98.9% (SDS-PAGE); 98.5% (SEC-HPLC)Colore e forma:LiquidNamilumab
CAS:<p>Namilumab (AMG203) is a humanised IgG1 monoclonal antibody that neutralises GM-CSF. rheumatoid arthritis and active axial spondyloarthritis.</p>Purezza:95%Colore e forma:LiquidTrabikibart
CAS:<p>Trabikibart (CSL311) is a human βc-specific antibody inhibiting IL-3, GM-CSF and IL-5, regulating eosinophil survival in chronic inflammatory disease research.</p>Purezza:95% - 95%Colore e forma:LiquidCabiralizumab
CAS:<p>Cabiralizumab is an anti-CSF1R monoclonal antibody that enhances T cell infiltration, inhibits osteoclasts, and is used in RA and immune-oncology research.</p>Purezza:95% - 95%Colore e forma:LiquidAnti-Mouse GM-CSF Antibody (MP1-22E9)
<p>Anti-Mouse GM-CSF Antibody is a rat-derived IgG2a isotype inhibitor that targets mouse granulocyte-macrophage colony-stimulating factor (GM-CSF).</p>Purezza:98%Colore e forma:Odour LiquidCSF1R-IN-19
CAS:<p>CSF1R-IN-19 is a robust inhibitor of CSF1R that influences the exchange of inflammatory factors between TAMs and glioma cells. It holds potential for cancer research [1].</p>Formula:C20H27N7OColore e forma:SolidPeso molecolare:381.47Sotuletinib dihydrochloride
CAS:<p>Sotuletinib (BLZ945) dihydrochloride is an orally administered, blood-brain barrier-permeable inhibitor specifically targeting CSF1-R with an IC50 of 1 nM.</p>Formula:C20H24Cl2N4O3SPurezza:98%Colore e forma:SolidPeso molecolare:471.4c-Fms-IN-9
CAS:<p>c-Fms-IN-9 inhibits c-FMS/uFMS and uKIT with IC50 <0.01μM and 0.1-1μM, from patent WO2014145023A1.</p>Formula:C21H23N7O2Purezza:98%Colore e forma:SolidPeso molecolare:405.45Leustroducsin A
CAS:<p>Leustroducsin A is an inducer of colony-stimulating factors (CSFs) extracted from Streptomyces platensis SANK 60191.</p>Formula:C32H52NO10PColore e forma:SolidPeso molecolare:641.73c-Fms-IN-7
CAS:<p>c-Fms-IN-7 is a cFMS inhibitor (IC50: 18.5 nM).</p>Formula:C26H24N6OSPurezza:98%Colore e forma:SolidPeso molecolare:468.57c-Fms-IN-8
CAS:<p>c-Fms-IN-8 is a colony-stimulating factor-1 receptor (CSF-1R, c-FMS) Type II inhibitor (IC50: 9.1 nM). It is compound 4a in the reference.</p>Formula:C27H30N2O5Purezza:98%Colore e forma:SolidPeso molecolare:462.54JNJ-28312141
CAS:<p>JNJ-28312141: oral CSF1R/FLT3 inhibitor, potential for treating acute myeloid leukemia, tumors, and bone events.</p>Formula:C26H32N6O2Purezza:98%Colore e forma:SolidPeso molecolare:460.57CSF1R-IN-4
CAS:<p>CSF1R-IN-4, a potent CSF-1R inhibitor, may impact TAM/glioma cell communication, with cancer research potential. (WO2021197276A1, compound 104)</p>Formula:C23H20N6O3Colore e forma:SolidPeso molecolare:428.44c-Fms-IN-10
CAS:<p>c-Fms-IN-10 is a thieno[3,2-d]pyrimidine derivative, an FMS kinase inhibitor with IC50 of 2 nM, exhibiting anti-tumor properties.</p>Formula:C22H19N7OSPurezza:98%Colore e forma:SolidPeso molecolare:429.5CSF1R-IN-13
CAS:<p>CSF1R-IN-13: potent cancer research CSF1R inhibitor impacting cell growth regulation.</p>Formula:C21H20N4O3Colore e forma:SolidPeso molecolare:376.41CSF1R-IN-8
CAS:<p>CSF1R-IN-8 (Compound 22) is a CSF-1R inhibitor (IC50: 0.012 μM).</p>Formula:C24H22N4O4Colore e forma:SolidPeso molecolare:430.46CSF1R-IN-10
CAS:<p>CSF1R-IN-10 (Compound 48) is a CSF-1R inhibitor (IC50: 0.005 μM).</p>Formula:C25H22N4O3Colore e forma:SolidPeso molecolare:426.47Leustroducsin C
CAS:<p>Leustroducsin C is an inducer of colony-stimulating factors CSF extracted from Streptomyces platensis SANK 60191.</p>Formula:C34H56NO10PColore e forma:SolidPeso molecolare:669.78CSF1R-IN-14
CAS:<p>CSF1R-IN-14, an isoindolinone derivative, powerfully inhibits CSF1R, with potential in cancer research. See WO2019134662A1, compound 1.</p>Formula:C23H22F3N5OColore e forma:SolidPeso molecolare:441.45
