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c-Fms

c-Fms

Gli inibitori di c-Fms prendono di mira il recettore del fattore stimolante delle colonie-1 (c-Fms), una tirosina chinasi coinvolta nella regolazione dei macrofagi e di altre cellule immunitarie. La segnalazione di c-Fms svolge un ruolo nella proliferazione, differenziazione e sopravvivenza di queste cellule. La disregolazione di c-Fms è associata a malattie come il cancro, condizioni infiammatorie e osteoporosi. Presso CymitQuimica, offriamo inibitori di c-Fms per supportare la tua ricerca in immunologia, oncologia e malattie infiammatorie.

Trovati 108 prodotti di "c-Fms"

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  • CSF1R-IN-12
    Targetmol
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    CSF1R-IN-12

    CAS:
    <p>CSF1R-IN-12 is an effective CSF1R inhibitor. CSF1R-IN-12 has research potential in cancer diseases.</p>
    Formula:C21H17F3N4O
    Colore e forma:Solid
    Peso molecolare:398.38

    Ref: TM-T61893

  • CSF1R-IN-7
    Targetmol
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    CSF1R-IN-7

    CAS:
    <p>CSF1R-IN-7 is a highly selective CSF-1R inhibitor with good brain penetration for treatment of diseases associated with microglia-mediated neuroinflammation.</p>
    Formula:C22H22N6O3
    Purezza:99.41% - 99.93%
    Colore e forma:Solid
    Peso molecolare:418.45

    Ref: TM-T62190

  • CSF1R-IN-9
    Targetmol
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    CSF1R-IN-9

    CAS:
    <p>CSF1R-IN-9 (Compound 46) is a CSF-1R inhibitor (IC50: 0.028 μM).</p>
    Formula:C26H26N4O2
    Colore e forma:Solid
    Peso molecolare:426.51

    Ref: TM-T62318

  • CSF1R-IN-6
    Targetmol
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    CSF1R-IN-6

    CAS:
    <p>CSF1R-IN-6, a compound, effectively inhibits macrophage CSF1R essential for survival and differentiation.</p>
    Formula:C20H18N8O3
    Colore e forma:Solid
    Peso molecolare:418.41

    Ref: TM-T62187

  • c-Fms-IN-2
    Targetmol
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    c-Fms-IN-2

    CAS:
    <p>c-Fms-IN-2 is an inhibitor of c-FMS kinase (IC50 = 24 nM).</p>
    Formula:C19H21N3O3
    Purezza:99.56%
    Colore e forma:Solid
    Peso molecolare:339.39

    Ref: TM-T10775

  • ABD-295
    Targetmol
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    ABD-295

    CAS:
    <p>ABD-295, a biphenylsulfide derivative, inhibits osteoclasts and prevents bone loss in vitro and in vivo.</p>
    Formula:C17H19F2NO3S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:355.4

    Ref: TM-T26512

  • c-Fms-IN-6
    Targetmol
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    c-Fms-IN-6

    CAS:
    <p>c-Fms-IN-6 is a potent inhibitor of c-FMS (IC50 ≤10 nM for unphosphorylated c-FMS) and also weakly inhibits unphosphorylated c-KIT and PDGFR (IC50: &gt; 1 μM).</p>
    Formula:C22H25N7O2
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:419.48

    Ref: TM-T10645

  • IACS-9439
    Targetmol
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    IACS-9439

    CAS:
    <p>IACS-9439 is a potent, selective, and orally active inhibitor of CSF1R, exhibiting a K(i) of 1 nM.</p>
    Formula:C23H26ClN7O3S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:516.02

    Ref: TM-T69759

  • c-Fms-IN-1
    Targetmol
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    c-Fms-IN-1

    CAS:
    <p>c-Fms-IN-1 is an inhibitor of c-FMS kinase (IC50 = 0.8 nM).</p>
    Formula:C22H27N5O2
    Purezza:99.94%
    Colore e forma:Solid
    Peso molecolare:393.48

    Ref: TM-T10643

  • Chiauranib
    Targetmol
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    Chiauranib

    CAS:
    <p>Chiauranib, a potent anticancer agent, inhibits angiogenesis kinases (VEGFR1-3, PDGFRα, c-Kit), Aurora B, and CSF1R with IC50 values of 1-9 nM.</p>
    Formula:C27H21N3O3
    Purezza:99.22%
    Colore e forma:Solid
    Peso molecolare:435.47

    Ref: TM-T35570

  • c-Fms-IN-3
    Targetmol
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    c-Fms-IN-3

    CAS:
    <p>c-Fms-IN-3 is a novel inhibitor of the c-FMS and can be used in studies about antirheumatic and anti-inflammatory diseases.</p>
    Formula:C23H30N6O
    Purezza:99.87%
    Colore e forma:Solid
    Peso molecolare:406.52

    Ref: TM-T10649

  • c-Fms-IN-13
    Targetmol
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    c-Fms-IN-13

    CAS:
    <p>c-Fms-IN-13 (compound 14) is a potent FMS kinase inhibitor (IC50= 17 nM). c-Fms-IN-13 is an anti-inflammatory agent.</p>
    Formula:C22H26N4O2
    Purezza:99.93% - 99.97%
    Colore e forma:Solid
    Peso molecolare:378.47

    Ref: TM-T61589

  • Pimicotinib
    Targetmol
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    Pimicotinib

    CAS:
    <p>Pimicotinib (ABSK021) is a potent CSF1R inhibitor with antitumor activity and can be used to study advanced solid tumors.</p>
    Formula:C22H24N6O3
    Purezza:99.8%
    Colore e forma:Solid
    Peso molecolare:420.46

    Ref: TM-T79157

  • CSF1R-IN-3
    Targetmol
    + Info

    CSF1R-IN-3

    CAS:
    <p>CSF1R-IN-3 is an orally effective CSF-1R inhibitor with an IC50 value of 2.1 nM.</p>
    Formula:C30H38N8O4
    Purezza:97.31%
    Colore e forma:Solid
    Peso molecolare:574.67

    Ref: TM-T64066

  • c-Fms-IN-14
    Targetmol
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    c-Fms-IN-14

    CAS:
    <p>c-Fms-IN-14 (Example 76) is a potent inhibitor of the c-Fms kinase with an IC50 of 4 nM, utilized in cancer and autoimmune disease research [1].</p>
    Formula:C26H24N6O
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:436.51

    Ref: TM-T79815

  • Axl/Mer/CSF1R-IN-2
    Targetmol
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    Axl/Mer/CSF1R-IN-2

    CAS:
    <p>Axl/Mer/CSF1R-IN-2 (Comp 4) serves as an inhibitor for Axl, Mer, and CSF1R [1].</p>
    Formula:C24H22F3N5O5
    Colore e forma:Solid
    Peso molecolare:517.46

    Ref: TM-T85780

  • Axl/Mer/CSF1R-IN-1
    Targetmol
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    Axl/Mer/CSF1R-IN-1

    CAS:
    <p>Axl/Mer-IN-1 is a compound that functions as an inhibitor for Axl/Mer receptor tyrosine kinase (Axl/Mer RTK) and CSF1R, exhibiting dissociation constants (Kds)</p>
    Formula:C25H24F3N5O5
    Colore e forma:Solid
    Peso molecolare:531.48

    Ref: TM-T72574

  • Ataquimast
    Targetmol
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    Ataquimast

    CAS:
    <p>Ataquimast is used in curing advanced receptor-positive breast cancer.</p>
    Formula:C11H14ClN3O
    Purezza:99.92%
    Colore e forma:Solid
    Peso molecolare:239.7

    Ref: TM-T30190

  • JTE-952
    Targetmol
    + Info

    JTE-952

    CAS:
    <p>JTE-952: oral, selective Type II CSF-1R inhibitor, IC50 = 13 nM for CSF1R, 261 nM for TrkA, effective in mouse arthritis model.</p>
    Formula:C30H34N2O6
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:518.6

    Ref: TM-T11729

  • CSF1R-IN-5
    Targetmol
    + Info

    CSF1R-IN-5

    CAS:
    <p>CSF1R-IN-5: Potent CSF1R inhibitor, may alter TAM/glioma inflammatory exchanges, potential cancer research tool. (WO2021197276A1, Compound 11)</p>
    Formula:C22H19N7O3
    Colore e forma:Solid
    Peso molecolare:429.43

    Ref: TM-T62364