c-Fms
Gli inibitori di c-Fms prendono di mira il recettore del fattore stimolante delle colonie-1 (c-Fms), una tirosina chinasi coinvolta nella regolazione dei macrofagi e di altre cellule immunitarie. La segnalazione di c-Fms svolge un ruolo nella proliferazione, differenziazione e sopravvivenza di queste cellule. La disregolazione di c-Fms è associata a malattie come il cancro, condizioni infiammatorie e osteoporosi. Presso CymitQuimica, offriamo inibitori di c-Fms per supportare la tua ricerca in immunologia, oncologia e malattie infiammatorie.
Trovati 116 prodotti per "c-Fms".
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Anti-CSF1R Antibody (5B661)
Anti-CSF1R Antibody (5B661) is a Mouse antibody targeting CSF1R. Anti-CSF1R Antibody (5B661) can be used in ELISA,ELISA(Cap).Colore e forma:Odour LiquidCSF1R Protein, Human, Recombinant
CSF1R Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 55.1 kDa and the accession number is P07333-1.Colore e forma:Lyophilized PowderPeso molecolare:55.1 kDa (predicted); 80-90 kDa (reducing condition, due to glycosylation)CSF1R Protein, Human, Recombinant (hFc & Avi), Biotinylated
CSF1R Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag.Colore e forma:Lyophilized PowderPeso molecolare:83.04 kDa (predicted); 110.87 kDa (reducing conditions)CSF1R Protein, Human, Recombinant (His & Avi)
M-CSFR/CSF1R/CD115 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag.Colore e forma:Lyophilized PowderPeso molecolare:57.4 kDa (predicted). Due to glycosylation, the protein migrates to 75-105 kDa based on Tris-Bis PAGE result.CSF1R Protein, Human, Recombinant (His & GST)
CSF1R Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag.Colore e forma:Lyophilized PowderPeso molecolare:76 kDa (predicted); 75 kDa (reducing conditions)PLX647
CAS:PLX647 is a highly selective dual FMS/KIT kinase inhibitor (IC50: 28/16 nM).Formula:C21H17F3N4Purezza:99.38%Colore e forma:White SolidPeso molecolare:382.38Ref: TM-T1925
2mg39,00€5mg57,00€1mL*10mM (DMSO)60,00€10mg86,00€25mg127,00€50mg178,00€100mg264,00€200mg389,00€AZD7507
CAS:AZD7507 is a CSF-1R inhibitor with an IC50 of 32 nM. AZD7507 has antitumor activity.Formula:C23H27FN6O3Purezza:99.55% - 99.78%Colore e forma:SolidPeso molecolare:454.5Ref: TM-T14380
1mg50,00€5mg110,00€1mL*10mM (DMSO)127,00€10mg161,00€25mg289,00€50mg419,00€100mg583,00€200mg787,00€Dovitinib
CAS:Dovitinib is an orally active, multi-targeted tyrosine kinase (RTK) inhibitor with anti-tumor effects.Cost-effective and quality-assured.
Formula:C21H21FN6OPurezza:99.35% - 99.92%Colore e forma:SolidPeso molecolare:392.43Ref: TM-T6289
500mgPrezzo su richiesta5mg47,00€10mg70,00€25mg126,00€50mg202,00€100mg328,00€200mg490,00€Sotuletinib
CAS:Sotuletinib (BLZ945) is an orally active, effective and specific CSF-1R inhibitor, >1000-fold selective against its closest receptor tyrosine kinase homologs.Formula:C20H22N4O3SPurezza:97.43% - 99.82%Colore e forma:Yellow SolidPeso molecolare:398.48Ref: TM-T6119
1mg34,00€5mg74,00€1mL*10mM (DMSO)82,00€10mg105,00€25mg163,00€50mg205,00€100mg358,00€500mg822,00€Edicotinib HCl
CAS:Edicotinib (JNJ-40346527), an oral CSF1R inhibitor, may block FMS autophosphorylation, impeding tumor cell growth.Formula:C27H36ClN5O2Colore e forma:SolidPeso molecolare:498.07PF 477736
CAS:PF 477736 (PF-736,PF-00477736) is a specifc, effective and ATP-competitive Chk1 inhibitor (Ki: 0.49 nM ) and also inhibits FGFR3, Aurora-A, VEGFR2, Flt3, Fms (Formula:C22H25N7O2Purezza:97.58% - 99.94%Colore e forma:Yellow SolidPeso molecolare:419.48GW2580
CAS:GW2580 (SC-203877) is a specific, oral-bioavailable CSF-1R inhibitor for c-FMS.Formula:C20H22N4O3Purezza:99.48% - >99.99%Colore e forma:Yellow SolidPeso molecolare:366.41Seralutinib
CAS:Seralutinib (GB002) is an inhibitor of inhaled PDGFRα and PDGFRβ. It is used in the study for pulmonary arterial hypertension.Formula:C27H27N5O3Purezza:99.09%Colore e forma:SolidPeso molecolare:469.54Ref: TM-T8900
1mg47,00€2mg62,00€5mg92,00€1mL*10mM (DMSO)92,00€10mg137,00€25mg236,00€50mg313,00€100mg497,00€PLX5622
CAS:PLX5622 is a selective, orally active and blood-brain barrier permeable CSF1R inhibitor. PLX5622 induces elimination of microglia. Cost effective and quality assured.Formula:C21H19F2N5OPurezza:98% - 99.97%Colore e forma:SolidPeso molecolare:395.41Ref: TM-T7100
1mg43,00€1mL*10mM (DMSO)77,00€5mg81,00€10mg118,00€25mg230,00€50mg385,00€100mg502,00€200mg710,00€29g11.700,00€PRN1371
CAS:PRN1371 is a specific and potent FGFR1-4 and CSF1R inhibitor (IC50s: 0.6/1.3/4.1/19.3/8.1 nM for FGFR1/2/3/4 and CSF1R).Formula:C26H30Cl2N6O4Purezza:98.65%Colore e forma:SolidPeso molecolare:561.46Ref: TM-TQ0015
1mg77,00€2mg100,00€5mg166,00€1mL*10mM (DMSO)200,00€10mg289,00€25mg492,00€50mg710,00€100mg973,00€GW786034B
CAS:Pazopanib HCl (Votrient) inhibits VEGFR1-3, PDGFR, FGFR, c-Kit, c-Fms with IC50 range 10-146 nM in cell-free assays.Formula:C21H23N7O2S·HClPurezza:99.87%Colore e forma:SolidPeso molecolare:473.98cFMS Receptor Inhibitor II
CAS:cFMS Receptor Inhibitor II is a CSF1R kinase inhibitorFormula:C23H20N4OPurezza:99.8%Colore e forma:SolidPeso molecolare:368.43Ref: TM-T5586
1mg47,00€2mg62,00€5mg92,00€1mL*10mM (DMSO)101,00€10mg145,00€25mg241,00€50mg356,00€100mg517,00€Vimseltinib
CAS:Vimseltinib (DCC-3014) is a c-FMS (CSF-IR) and c-Kit dual inhibitor (IC50s: <0.01 μM and 0.1-1 μM).Formula:C23H25N7O2Purezza:99.05% - 99.57%Colore e forma:SolidPeso molecolare:431.49Ref: TM-T10652
1mg87,00€5mg178,00€1mL*10mM (DMSO)203,00€10mg295,00€25mg505,00€50mg690,00€100mg888,00€Linifanib
CAS:Linifanib (AL-39324) (ABT-869) is a novel, potent ATP-competitive VEGFR/PDGFR inhibitor for KDR (IC50: 4 nM), CSF-1R (IC50: 3 nM), Flt-1/3 (IC50: 3/4 nM) andFormula:C21H18FN5OPurezza:98% - 98.24%Colore e forma:White SolidPeso molecolare:375.4Ref: TM-T2514
5mg48,00€1mL*10mM (DMSO)50,00€10mg80,00€25mg119,00€50mg178,00€100mg259,00€200mg477,00€500mg772,00€OSI-930
CAS:OSI-930 is an oral c-Kit/VEGFR-2 inhibitor targeting tumor growth and angiogenesis.Formula:C22H16F3N3O2SPurezza:99.67%Colore e forma:White SolidPeso molecolare:443.44
