VEGFR
Gli inibitori del recettore del fattore di crescita endoteliale vascolare (VEGFR) sono composti che bloccano la segnalazione del VEGFR, un recettore chiave nella via VEGF, cruciale per l'angiogenesi. Gli inibitori del VEGFR impediscono la formazione di nuovi vasi sanguigni che forniscono nutrienti e ossigeno ai tumori, inibendo così la crescita tumorale. Questi inibitori sono ampiamente utilizzati nella terapia e nella ricerca sul cancro per studiare i meccanismi dell'angiogenesi e sviluppare trattamenti anticancro. Presso CymitQuimica, offriamo una gamma completa di inibitori del VEGFR di alta qualità per supportare la tua ricerca in oncologia, biologia vascolare e angiogenesi.
Trovati 250 prodotti di "VEGFR"
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Conbercept
CAS:Conbercept (KH902) is a fusion protein comprising the second immunoglobulin C-like domain of FLT1 and the third and fourth immunoglobulin C-like domains of KDRPurezza:98%Colore e forma:LiquidAngiogenesis related Compound Library
<p>A unique collection of 1353 proangiogenic and antiangiogenic compounds for new targets identification, research in mechanisms of angiogenesis, and high</p>Colore e forma:Odour SolidSU 4981
CAS:<p>SU 4981 is an inhibitor of VEGFR and a modulator of tyrosine kinase activity.</p>Formula:C19H18N2O2Purezza:95.4%Colore e forma:SoildPeso molecolare:306.36FDA-Approved Kinase Inhibitor Library
<p>A unique collection of 263 kinase inhibitors/regulators for specific targeting of kinases, ready for high-throughput screening and high-content screening.</p>Colore e forma:Liquid5Z-7-Oxozeaenol
CAS:<p>5Z-7-Oxozeaenol: TGF-β-activated kinase 1 inhibitor, IC50 8.1 nM; VEGF-R2 inhibitor, IC50 52 nM; weak MEK1 inhibitor, IC50 411 nM.</p>Formula:C19H22O7Purezza:99%Colore e forma:SolidPeso molecolare:362.37Kinase Inhibitor Library
<p>A unique collection of 2720 kinase inhibitors/regulators for high throughput screening and high content screening for drug discovery in kinase related diseases;</p>Colore e forma:Odour SolidTovecimig
Tovecimig is a G1-scFvlh_L-κ type bispecific antibody targeting VEGFA/DLL4.Colore e forma:Odour LiquidVEGF-IN-1
VEGF-IN-1 (compound 6) reduces the release of VEGF in U87-MG cells and inhibits angiogenesis in vitro. Additionally, it suppresses cell proliferation by inducing autophagy in tumor cells, with an IC50 value of 28.35 μM against U87-MG cells.Formula:C27H22Cl2N4RuColore e forma:SolidPeso molecolare:574.47VEGFR-2-IN-29
CAS:VEGFR-2-IN-29 is a VEGFR2 inhibitor.Formula:C16H11N3O3Purezza:99.59%Colore e forma:SolidPeso molecolare:293.28VEGFR-2-IN-35
VEGFR-2-IN-35 (compound 7) is a potent inhibitor of VEGFR-2, exhibiting an IC50 of 37 nM.Formula:C25H19N3O3Purezza:98%Colore e forma:SolidPeso molecolare:409.44VEGFR-2-IN-59
VEGFR-2-IN-59 (Compound 3h) is an inhibitor of VEGFR2 with an IC50 of 3.73 µM. It exhibits cytotoxicity in cancer cell lines A549, HT-29, A375, MCF7, and NHDF, with IC50 values of 20.91, 19.70, 9.63, 17.43, and 20.71 μM, respectively. VEGFR-2-IN-59 also inhibits tubular structure formation and demonstrates anti-angiogenic properties.Formula:C19H20N6O4Colore e forma:SolidPeso molecolare:396.4VEGFR-2-IN-55
VEGFR-2-IN-55 (Compound 30) is an effective VEGFR-2 kinase inhibitor with an IC50 of 1.24 nM and exhibits anti-tumor activity.Colore e forma:Odour SolidAntiproliferative agent-57
<p>Antiproliferative agent-57 (compound M2) is a tumor angiogenesis inhibitor that suppresses VEGF secretion in SiHa cells under hypoxic conditions without inducing cytotoxicity (IC50=0.68 μM). It modulates the PI3K/AKT/mTOR and MAPK signaling pathways in tumor cells, thereby inhibiting the expression of HIF-1α and VEGF within tumor tissues.</p>Colore e forma:Odour SolidAbicipar pegol
CAS:<p>Abicipar pegol is an anti-VEGF DARPin for ocular diseases, reducing retinal thickness and leakage.</p>Colore e forma:LiquidArginyl-Glutamine
CAS:Arginyl-Glutamine (Arg-Gln) is a dipeptide nutritional supplement that protects neonatal mice from hyperoxia-induced lung injury, lowering VEGF levels.Formula:C11H22N6O4Purezza:95.2%Colore e forma:SolidPeso molecolare:302.33GNQWFI
CAS:GNQWFI, an anti-Flt1 peptide, functions as a VEGFR1-specific antagonist. It inhibits interactions between VEGFR1 and various ligands, such as VEGFA, VEGFB, and placental growth factor (PIGF), and suppresses VEGF-induced endothelial cell migration and tubulogenesis. GNQWFI holds potential for research in cancer, asthma, and other ocular diseases.Formula:C37H49N9O9Colore e forma:SolidPeso molecolare:763.84Acrizanib
CAS:Acrizanib (LHA510) is a VEGFR-2 inhibitor, with an IC50 of 17.4 nM for BaF3-VEGFR-2.Formula:C20H18F3N7O2Purezza:98.71% - 99.64%Colore e forma:SolidPeso molecolare:445.4Sozinibercept
CAS:Sozinibercept (OPT 302; VGX-300), a VEGFR-3 inhibitor, blocks VEGF-C/D to curb angiogenesis and vascular leakage, and treats rat diabetic retinal edema.Colore e forma:LiquidRanibizumab
CAS:Ranibizumab is a humanized monoclonal antibody fragment designed to target and inhibit vascular endothelial growth factor (VEGF), including VEGF110, VEGF121,Purezza:98%Colore e forma:LiquidPeso molecolare:149.19KDElpamotide
CAS:Elpamotide is a vaccine consisting of a VEGFR2-169 peptide.Formula:C47H76N16O13Purezza:98%Colore e forma:SolidPeso molecolare:1073.21
